Dipòsit Digital de Documents de la UAB 22 registres trobats  1 - 10següentfinal  anar al registre: La cerca s'ha fet en 0.01 segons. 
1.
17 p, 2.8 MB Soluble AXL is a novel blood marker for early detection of pancreatic ductal adenocarcinoma and differential diagnosis from chronic pancreatitis / Martínez Bosch, Neus (Institut Hospital del Mar d'Investigacions Mèdiques) ; Cristóbal, Helena (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Iglesias, Mar (Universitat Autònoma de Barcelona. Departament de Ciències Morfològiques) ; Gironella, Meritxell (Hospital Clínic i Provincial de Barcelona) ; Barranco, Luis (Institut Hospital del Mar d'Investigacions Mèdiques) ; Visa, Laura (Hospital del Mar (Barcelona, Catalunya)) ; Calafato, Domenico (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Jiménez-Parrado, Silvia (Centro Nacional de Investigaciones Oncológicas, Madrid) ; Earl, Julie (Instituto Ramón y Cajal de Investigación Sanitaria (Madrid)) ; Carrato, Alfredo (Instituto Ramón y Cajal de Investigación Sanitaria (Madrid)) ; Manero-Rupérez, Noemí (Institut Hospital del Mar d'Investigacions Mèdiques) ; Moreno Merino, Mireia (Institut Hospital del Mar d'Investigacions Mèdiques) ; Morales, Albert (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Guerra, Carmen (Centro Nacional de Investigaciones Oncológicas, Madrid) ; Navarro, Pilar (Institut d'Investigacions Biomèdiques de Barcelona) ; García de Frutos, Pablo (Institut d'Investigacions Biomèdiques de Barcelona)
Early diagnosis is crucial for patients with pancreatic ductal adenocarcinoma (PDAC). The AXL receptor tyrosine kinase is proteolytically processed releasing a soluble form (sAXL) into the blood stream. [...]
2021 - 10.1016/j.ebiom.2021.103797
EBioMedicine, Vol. 75 (december 2021)  
2.
12 p, 2.0 MB Personalised, image-guided, noninvasive brain stimulation in gliomas : Rationale, challenges and opportunities / Sprugnoli, Giulia (Harvard Medical School. Berenson-Allen Center for Noninvasive Brain Stimulation) ; Rossi, Simone (University of Siena. Department of Medicine, Surgery and Neuroscience, Neurology and Clinical Neurophysiology Unit) ; Rotenberg, Alexander (Harvard Medical School. Department of Neurology and Division of Epilepsy and Clinical Neurophysiology) ; Pascual-Leone, Alvaro (Institut Germans Trias i Pujol. Institut Guttmann) ; El-Fakhri, Georges (Harvard Medical School, Boston. Department of Radiology) ; Golby, Alexandra J. (Harvard Medical School. Department of Neurosurgery and Radiology) ; Santarnecchi, Emiliano (Harvard Medical School. Berenson-Allen Center for Noninvasive Brain Stimulation) ; Universitat Autònoma de Barcelona
Malignant brain tumours are among the most aggressive human cancers, and despite intensive efforts made over the last decades, patients' survival has scarcely improved. Recently, high-grade gliomas (HGG) have been found to be electrically integrated with healthy brain tissue, a communication that facilitates tumour mitosis and invasion. [...]
2021 - 10.1016/j.ebiom.2021.103514
EBioMedicine, Vol. 70 (august 2021)  
3.
12 p, 3.7 MB The four horsemen of a viral Apocalypse : The pathogenesis of SARS-CoV-2 infection (COVID-19) / Domingo, Pere (Institut d'Investigació Biomèdica Sant Pau) ; Mur, Isabel (Institut d'Investigació Biomèdica Sant Pau) ; Pomar, Virginia (Institut d'Investigació Biomèdica Sant Pau) ; Corominas, Hèctor (Institut d'Investigació Biomèdica Sant Pau) ; Casademont i Pou, Jordi (Institut d'Investigació Biomèdica Sant Pau) ; Benito, Natividad (Institut d'Investigació Biomèdica Sant Pau) ; Universitat Autònoma de Barcelona
The pathogenesis of coronavirus disease 2019 (COVID-19) may be envisaged as the dynamic interaction between four vicious feedback loops chained or happening at once. These are the viral loop, the hyperinflammatory loop, the non-canonical renin-angiotensin system (RAS) axis loop, and the hypercoagulation loop. [...]
2020 - 10.1016/j.ebiom.2020.102887
EBioMedicine, Vol. 58 (august 2020) , p. 102887  
4.
9 p, 1.6 MB Differential miRNAs in acute spontaneous coronary artery dissection : Pathophysiological insights from a potential biomarker / Lozano-Prieto, Marta (Hospital Universitario de la Princesa (Madrid)) ; Adlam, David (NIHR Leicester Biomedical Research Centre) ; García-Guimaraes, Marcos (Hospital del Mar (Barcelona, Catalunya)) ; Sanz-García, Ancor (Hospital Universitario de la Princesa (Madrid)) ; Vera-Tomé, Paula (Hospital Universitario de la Princesa (Madrid)) ; Rivero, Fernando (Hospital Universitario de la Princesa (Madrid)) ; Cuesta, Javier (Hospital Universitario de la Princesa (Madrid)) ; Bastante, Teresa (Hospital Universitario de la Princesa (Madrid)) ; Baranowska-Clarke, Anna A. (NIHR Leicester Biomedical Research Centre) ; Vara, Alicia (Hospital Universitario de la Princesa (Madrid)) ; Martin-Gayo, Enrique (Hospital Universitario de la Princesa (Madrid)) ; Vicente-Manzanares, Miguel (Instituto de Biología Molecular y Celular del Cáncer USAL-CSIC) ; Martín, Pilar (Centro Nacional de Investigaciones Cardiovasculares, Madrid) ; Samani, Nilesh J (NIHR Leicester Biomedical Research Centre) ; Sánchez-Madrid, Francisco (Hospital Universitario de la Princesa (Madrid)) ; Alfonso, Fernando (NIHR Leicester Biomedical Research Centre) ; de la Fuente, Hortensia (Hospital Universitario de la Princesa (Madrid)) ; Universitat Autònoma de Barcelona
Spontaneous Coronary Artery Dissection (SCAD) is an important cause of acute coronary syndromes, particularly in young to middle-aged women. Differentiating acute SCAD from coronary atherothrombosis remains a major clinical challenge. [...]
2021 - 10.1016/j.ebiom.2021.103338
EBioMedicine, Vol. 66 (april 2021)  
5.
8 p, 1.4 MB Efficacy of linezolid on Treponema pallidum, the syphilis agent : A preclinical study / Haynes, Austin M. (University of Washington. Department of Medicine) ; Giacani, Lorenzo (University of Washington. Department of Global Health) ; Mayans, Marti Vall (Institut Germans Trias i Pujol. Fundació de Lluita Contra la Sida) ; Ubals, Maria (Institut Germans Trias i Pujol. Fundació de Lluita Contra la Sida) ; Nieto, Carles (Laboratorio Reig Jofre) ; Pérez-Mañá, Clara (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ; Quintó, Llorenç (Hospital Clínic i Provincial de Barcelona) ; Romeis, Emily (University of Washington. Department of Medicine) ; Mitjà, Oriol (Institut Germans Trias i Pujol. Fundació de Lluita Contra la Sida)
Penicillin G, the current standard treatment for syphilis, has important drawbacks, but virtually no preclinical or clinical studies have been performed to identify viable alternatives. We tested, both in vitro and in vivo, three marketed antibiotics with adequate pharmacological properties to treat syphilis. [...]
2021 - 10.1016/j.ebiom.2021.103281
EBioMedicine, Vol. 65 (march 2021)  
6.
12 p, 2.8 MB Efficacy of adeno-associated virus gene therapy in a MNGIE murine model enhanced by chronic exposure to nucleosides / Vila-Julià, Ferran (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Cabrera-Pérez, Raquel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Cámara, Yolanda (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Molina-Berenguer, Miguel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Lope-Piedrafita, Silvia (Universitat Autònoma de Barcelona. Servei de Ressonància Magnètica Nuclear) ; Hirano, Michio (Department of Neurology, H. Houston Merritt Neuromuscular Research Center, Columbia University Irving Medical Center) ; Mingozzi, Federico (Spark Therapeutics) ; Torres-Torronteras, Javier (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Martí, Ramon A. (Hospital Universitari Vall d'Hebron. Institut de Recerca)
Preclinical studies have shown that gene therapy is a feasible approach to treat mitochondrial neurogastrointestinal encephalomyopathy (MNGIE). However, the genetic murine model of the disease (Tymp/Upp1 double knockout, dKO) has a limited functional phenotype beyond the metabolic imbalances, and so the studies showing efficacy of gene therapy have relied almost exclusively on demonstrating correction of the biochemical phenotype. [...]
2020 - 10.1016/j.ebiom.2020.103133
EBioMedicine, Vol. 62 (november 2020)  
7.
10 p, 757.2 KB Shorter androgen receptor polyQ alleles protect against life-threatening COVID-19 disease in European males / Baldassarri, Margherita (University of Siena. Department of Medical Biotechnologies) ; Picchiotti, Nicola (University of Pavia. Department of Mathematics) ; Fava, Francesca (Azienda Ospedaliero-Universitaria Senese (Itàlia)) ; Fallerini, Chiara (University of Siena. Department of Medical Biotechnologies) ; Benetti, Elisa (University of Siena. Department of Medical Biotechnologies) ; Daga, Sergio (University of Siena. Department of Medical Biotechnologies) ; Valentino, Floriana (University of Siena. Department of Medical Biotechnologies) ; Doddato, Gabriella (University of Siena. Department of Medical Biotechnologies) ; Furini, Simone (University of Siena. Department of Medical Biotechnologies) ; Giliberti, Annarita (University of Siena. Department of Medical Biotechnologies) ; Tita, Rossella (Azienda Ospedaliero-Universitaria Senese (Itàlia)) ; Amitrano, Sara (Azienda Ospedaliero-Universitaria Senese (Itàlia)) ; Bruttini, Mirella (Azienda Ospedaliero-Universitaria Senese (Itàlia)) ; Croci, Susanna (University of Siena. Department of Medical Biotechnologies) ; Meloni, Ilaria (University of Siena. Department of Medical Biotechnologies) ; Pinto, Anna Maria (Azienda Ospedaliero-Universitaria Senese (Itàlia)) ; Iuso, Nicola (University of Siena. Department of Medical Biotechnologies) ; Gabbi, Chiara ; Sciarra, Francesca (Sapienza University of Rome. Department of Experimental Medicine) ; Venneri, Mary Anna (Sapienza University of Rome. Department of Experimental Medicine) ; Gori, Marco (Université Côte d'Azur) ; Sanarico, Maurizio ; Crawley, Francis P. (Good Clinical Practice Alliance-Europe (GCPA) and Strategic Initiative for Developing Capacity in Ethical Review-Europe (SIDCER) (Leuven, Bèlgica)) ; Pagotto, Uberto (University of Bologna. Department of Medical and Surgical Sciences) ; Fanelli, Flaminia (University of Bologna. Department of Medical and Surgical Sciences) ; Mezzullo, Marco (University of Bologna. Department of Medical and Surgical Sciences) ; Dominguez-Garrido, Elena (Fundación Rioja Salud. Molecular Diagnostic Unit) ; Planas-Serra, Laura (Spanish Covid HGE) ; Schlüter, Agatha (Spanish Covid HGE) ; Colobrán Oriol, Roger (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Soler-Palacín, Pere (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Lapunzina, Pablo (Hospital Universitario La Paz (Madrid)) ; Tenorio, Jair (Hospital Universitario La Paz (Madrid)) ; Pujol, Aurora (Institució Catalana de Recerca i Estudis Avançats) ; Castagna, Maria Grazia (University of Siena. Department of Medical, Surgical and Neurological Sciences) ; Marcelli, Marco (Baylor College of Medicine (Houston, Estats Units d'Amèrica). Department of Medicine) ; Isidori, Andrea M. (Sapienza University of Rome. Department of Experimental Medicine) ; Renieri, Alessandra (Azienda Ospedaliero-Universitaria Senese (Itàlia)) ; Frullanti, Elisa (University of Siena. Department of Medical, Surgical and Neurological Sciences) ; Mari, Francesca (Azienda Ospedaliero-Universitaria Senese (Itàlia)) ; Universitat Autònoma de Barcelona
While SARS-CoV-2 similarly infects men and women, COVID-19 outcome is less favorable in men. Variability in COVID-19 severity may be explained by differences in the host genome. We compared poly-amino acids variability from WES data in severely affected COVID-19 patients versus SARS-CoV-2 PCR-positive oligo-asymptomatic subjects. [...]
2021 - 10.1016/j.ebiom.2021.103246
EBioMedicine, Vol. 65 (february 2021) , p. 103246  
8.
12 p, 1.1 MB Extremely low viral reservoir in treated chronically HIV-1-infected individuals / Gálvez, Cristina (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Urrea, Víctor (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Dalmau, Judith (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Jiménez Valero, Montserrat (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Pérez-Álvarez, Núria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Monceaux, Valérie (Institut Pasteur, Unité HIV Inflammation et Persistance, Paris, France) ; Huot, Nicolas (Institut Pasteur, Unité HIV Inflammation et Persistance, Paris, France) ; Leal, Lorna (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; González Soler, Victoria (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ; González-Cao, Maria (Translational Cancer Research Unit, Instituto Oncológico Dr Rosell, Dexeus University Hospital, Barcelona, Spain) ; Müller-Trutwin, Michaela (Institut Pasteur, Unité HIV Inflammation et Persistance, Paris, France) ; Sáez-Cirión, Asier (Institut Pasteur, Unité HIV Inflammation et Persistance, Paris, France) ; García, Felipe (Institut Pasteur, Unité HIV Inflammation et Persistance, Paris, France) ; Blanco, Julià (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Martínez Picado, Francisco Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Salgado, Maria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Universitat Autònoma de Barcelona
Small viral reservoirs are found predominantly in HIV-1 controllers and individuals treated during acute/early HIV-1 infection. However, other HIV + individuals could naturally also harbour low viral reservoirs. [...]
2020 - 10.1016/j.ebiom.2020.102830
EBioMedicine, Vol. 57 (june 2020)  
9.
11 p, 2.3 MB First-in-human PeriCord cardiac bioimplant : scalability and GMP manufacturing of an allogeneic engineered tissue graft / Prat-Vidal, Cristina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Rodríguez-Gómez, Luciano (Cell Therapy Service, Banc de Sang i Teixits, Edifici Dr. Frederic Duran i Jordà) ; Aylagas, Miriam (Hospital Universitari Vall d'Hebron) ; Nieto-Nicolau, Nuria (Banc de Sang i Teixits (Barcelona, Catalunya)) ; Gastelurrutia, Paloma (Institut d'Investigació Biomèdica de Bellvitge) ; Agustí, Elba (Banc de Sang i Teixits (Barcelona, Catalunya)) ; Gálvez-Montón, Carolina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Jorba, Ignasi (Institut de Bioenginyeria de Catalunya) ; Teis, Albert (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Monguió-Tortajada, Marta (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Rudilla, F (Centro de Investigación Biomédica en Red en Enfermedades Cardiovasculares) ; Vives Armengol, Joaquim (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Torrents-Zapata, Silvia (Banc de Sang i Teixits (Barcelona, Catalunya)) ; Coca, María Isabel (Banc de Sang i Teixits (Barcelona, Catalunya)) ; Reales, Laura (Banc de Sang i Teixits (Barcelona, Catalunya)) ; Cámara-Rosell, María Luisa (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Cediel, Germán (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Farré, Ramon (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Coll, Ruth (Research and Education. Banc de Sang i Teixits) ; Navajas, Daniel (Institut de Bioenginyeria de Catalunya) ; Vilarrodona, Anna (Banc de Sang i Teixits (Barcelona, Catalunya)) ; García López, Joan (Banc de Sang i Teixits (Barcelona, Catalunya)) ; Muñoz-Guijosa, Christian (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Querol, Sergi (Hospital Universitari Vall d'Hebron) ; Bayés-Genís, Antoni (Universitat Autònoma de Barcelona. Departament de Medicina) ; Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol ; VHIR Vall d'Hebron Institut de Recerca ; Universitat Autònoma de Barcelona. Departament de Medicina
Small cardiac tissue engineering constructs show promise for limiting post-infarct sequelae in animal models. This study sought to scale-up a 2-cm 2 preclinical construct into a human-size advanced therapy medicinal product (ATMP; PeriCord), and to test it in a first-in-human implantation. [...]
2020 - 10.1016/j.ebiom.2020.102729
EBioMedicine, Vol. 54 (april 2020)  
10.
14 p, 3.9 MB Age-related metabolic changes limit efficacy of deoxynucleoside-based therapy in thymidine kinase 2-deficient mice / Blázquez-Bermejo, Cora (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Molina-Granada, David (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Vila-Julià, Ferran (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Jiménez-Heis, Daniel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Zhou, Xiaoshan (Karolinska University Hospital and Karolinska Institutet (Suècia)) ; Torres-Torronteras, Javier (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Karlsson, Anna (Karolinska University Hospital and Karolinska Institutet (Suècia)) ; Martí, Ramon A. (Centro de Investigación Biomédica en Red de Enfermedades Raras) ; Cámara, Yolanda (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Universitat Autònoma de Barcelona
Thymidine kinase 2 (TK2) catalyses the phosphorylation of deoxythymidine (dThd) and deoxycytidine (dCtd) within mitochondria. TK2 deficiency leads to mtDNA depletion or accumulation of multiple deletions. [...]
2019 - 10.1016/j.ebiom.2019.07.042
EBioMedicine, Vol. 46 (july 2019) , p. 342-355  

Dipòsit Digital de Documents de la UAB : 22 registres trobats   1 - 10següentfinal  anar al registre:
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