|
1.
|
|
9 p, 1.5 MB |
Trabectedin and RAdiotherapy in Soft Tissue Sarcoma (TRASTS) : Results of a Phase I Study in Myxoid Liposarcoma from Spanish (GEIS), Italian (ISG), French (FSG) Sarcoma Groups
/
Gronchi, Alessandro (Fondazione IRCCS Istituto Nazionale dei Tumori) ;
Hindi, Nadia (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Cruz, Josefina (University Hospital Canarias) ;
Blay, Jean-Yves (Center Leon Berard (Lyon)) ;
López Pousa, Antonio (Institut d'Investigació Biomèdica Sant Pau) ;
Italiano, Antoine (Institute Bergonie - Bourdeaux) ;
Alvarez, Rosa (Hospital General Universitario Gregorio Marañón) ;
Gutierrez, Antonio (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ;
Rincón, Inmaculada (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Sangalli, Claudia (Fondazione IRCCS Istituto Nazionale dei Tumori) ;
Pérez Aguiar, José Luis (Hospital Universitario Canarias) ;
Romero, Jesús (Hospital Universitario Puerta de Hierro Majadahonda (Madrid)) ;
Morosi, Carlo (Fondazione IRCCS Istituto Nazionale dei Tumori) ;
Sunyach, Marie Pierre (Center Leon Berard) ;
Sanfilippo, Roberta (Fondazione IRCCS Istituto Nazionale dei Tumori) ;
Romagosa, Cleofe (Hospital Universitari Vall d'Hebron) ;
Ranchere-Vince, Dominique (Center Leon Berard) ;
Dei Tos, Angelo (University of Padova) ;
Casali, Paolo G. (University of Milan) ;
Martin-Broto, Javier (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Universitat Autònoma de Barcelona
Myxoid liposarcoma (ML) exhibits a special sensitivity to trabectedin (T) and radiation therapy (RT). Preclinical data suggest a synergistic effect. We aimed to study safety, feasibility and activity of the administration of pre-operative concurrent T and RT in patients affected by localized resectable ML. [...]
2019 -  10.1016/j.eclinm.2019.03.007
EClinicalMedicine, Vol. 9 (march 2019) , p. 35-43
|
|
|
2.
|
|
11 p, 1.4 MB |
Aspirin for primary prevention of ST segment elevation myocardial infarction in persons with diabetes and multiple risk factors
/
Bugiardini, Raffaele (University of Bologna) ;
Pavasović, S. (Department for Cardiovascular Diseases. University Hospital Centre Zagreb. University of Zagreb) ;
Yoon, J. (Google Cloud AI) ;
van der Schaar, M. (University of Cambridge) ;
Kedev, S. (University "Ss. Cyril and Methodius") ;
Vavlukis, M. (University "Ss. Cyril and Methodius") ;
Vasiljevic, Z. (University of Belgrade) ;
Bergami, M. (University of Bologna) ;
Miličić, D. (University of Zagreb) ;
Manfrini, O. (University of Bologna) ;
Cenko, Edina (University of Bologna) ;
Badimon, Lina (Institut d'Investigació Biomèdica Sant Pau)
Controversy exists as to whether low-dose aspirin use may give benefit in primary prevention of cardiovascular (CV) events. We hypothesized that the benefits of aspirin are underevaluated. We investigated 12,123 Caucasian patients presenting to hospital with acute coronary syndromes as first manifestation of CV disease from 2010 to 2019 in the ISACS-TC multicenter registry (ClinicalTrials. [...]
2020 - 10.1016/j.eclinm.2020.100548
EClinicalMedicine, Vol. 27 (october 2020) , p. 100548
|
|
|
3.
|
|
13 p, 1.8 MB |
Determinants of long-term survival in late HIV presenters : The prospective PISCIS cohort study
/
Martin-Iguacel, Raquel (Odense University Hospital (Dinamarca)) ;
Reyes-Urueña, Juliana (Institut Germans Trias i Pujol. Centre d'Estudis Epidemiològics sobre les Infeccions de Transmissió Sexual i Sida de Catalunya) ;
Bruguera Riera, Andreu (Institut Germans Trias i Pujol. Centre d'Estudis Epidemiològics sobre les Infeccions de Transmissió Sexual i Sida de Catalunya) ;
Aceitón, Jordi (Institut Germans Trias i Pujol. Centre d'Estudis Epidemiològics sobre les Infeccions de Transmissió Sexual i Sida de Catalunya) ;
Díaz, Yesika (Institut Germans Trias i Pujol. Centre d'Estudis Epidemiològics sobre les Infeccions de Transmissió Sexual i Sida de Catalunya) ;
Moreno-Fornés, Sergio (Institut Germans Trias i Pujol. Centre d'Estudis Epidemiològics sobre les Infeccions de Transmissió Sexual i Sida de Catalunya) ;
Domingo, Pere (Institut d'Investigació Biomèdica Sant Pau) ;
Burgos, Joaquín (Hospital Universitari Vall d'Hebron) ;
Tiraboschi, Juan Manuel (Hospital Universitari de Bellvitge) ;
Johansen, Isik Somuncu (Odense University Hospital (Dinamarca)) ;
Álvarez, Hortensia (Complejo Hospitalario Universitario de Ferrol) ;
Miró, Josep M. (Instituto de Salud Carlos III) ;
Casabona-Barbarà, Jordi (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Llibre, Josep M.. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Universitat Autònoma de Barcelona
Late HIV diagnosis (i. e CD4≤350 cells/µL) is associated with poorer outcomes. However, determinants of long-term mortality and factors influencing immune recovery within the first years after antiretroviral treatment (ART) initiation are poorly defined. [...]
2022 - 10.1016/j.eclinm.2022.101600
EClinicalMedicine, Vol. 52 (august 2022)
|
|
|
4.
|
|
14 p, 1.7 MB |
Immunogenic dynamics and SARS-CoV-2 variant neutralisation of the heterologous ChAdOx1-S/BNT162b2 vaccination : Secondary analysis of the randomised CombiVacS study
/
García-Pérez, Javier (Instituto de Salud Carlos III) ;
González-Pérez, María (Instituto de Salud Carlos III) ;
Castillo de la Osa, María (Instituto de Salud Carlos III) ;
Borobia, Alberto M. (Universidad Autónoma de Madrid) ;
Castaño, Luis (Hospital Universitario de Cruces (Barakaldo, País Basc)) ;
Bertrán, María Jesús (Hospital Clínic i Provincial de Barcelona) ;
Campins Martí, Magda (Hospital Universitari Vall d'Hebron) ;
Portolés, Antonio (Universidad Complutense de Madrid) ;
Lora, David (Universidad Complutense de Madrid) ;
Bermejo, Mercedes (Instituto de Salud Carlos III) ;
Conde, Patricia (Instituto de Salud Carlos III) ;
Hernández-Gutierrez, Lourdes (Instituto de Salud Carlos III) ;
Carcas, Antonio (Hospital Universitario La Paz (Madrid)) ;
Arana-Arri, Eunate (Hospital Universitario de Cruces (Barakaldo, País Basc)) ;
Tortajada, Marta (Hospital Clínic i Provincial de Barcelona) ;
Fuentes Camps, Inmaculada (Hospital Universitari Vall d'Hebron) ;
Ascaso, Ana (Hospital Clínico San Carlos (Madrid)) ;
García-Morales, María Teresa (Universidad Complutense de Madrid) ;
Erick de la Torre-Tarazona, Humberto (Instituto de Salud Carlos III) ;
Arribas, Jose (Hospital Universitario La Paz (Madrid)) ;
Imaz-Ayo, Natale (Hospital Universitario de Cruces (Barakaldo, País Basc)) ;
Mellado-Pau, Eugènia (Hospital Clínic i Provincial de Barcelona) ;
Agustí Escasany, M. Antònia (Hospital Universitari Vall d'Hebron) ;
Pérez-Ingidua, Carla (Hospital Clínico San Carlos (Madrid)) ;
Gómez de la Cámara, Agustín (Universidad Complutense de Madrid) ;
Ochando, Jordi (Instituto de Salud Carlos III) ;
Belda-Iniesta, Cristobal (Instituto de Salud Carlos III) ;
Frías, Jesús (Hospital Universitario La Paz (Madrid)) ;
Alcami, Jose (Instituto de Salud Carlos III) ;
Pérez-Olmeda, Mayte (Instituto de Salud Carlos III) ;
Universitat Autònoma de Barcelona
The CombiVacS study was designed to assess immunogenicity and reactogenicity of the heterologous ChAdOx1-S/BNT162b2 combination, and 14-day results showed a strong immune response. The present secondary analysis addresses the evolution of humoral and cellular response up to day 180. [...]
2022 - 10.1016/j.eclinm.2022.101529
EClinicalMedicine, Vol. 50 (july 2022)
|
|
|
5.
|
|
11 p, 519.8 KB |
Prevalence and clinical impact of alcohol withdrawal syndrome in alcohol-associated hepatitis and the potential role of prophylaxis : a multinational, retrospective cohort study
/
Marti-Aguado, David (Institut d'Investigació Biomèdica (INCLIVA)) ;
Gougol, Amir (University of California) ;
Gomez-Medina, Concepcion (Institut d'Investigació Biomèdica (INCLIVA)) ;
Jamali, Arsia (University of Pittsburgh Medical Center) ;
Abo-Zed, Abdelrhman (University of Pittsburgh Medical Center) ;
Morales-Arraez, Dalia (Hospital Universitario de Canarias (La Laguna)) ;
Jimenez-Sosa, Alejandro (Hospital Universitario de Canarias (La Laguna)) ;
Burns, Keith (University of Pittsburgh Medical Center) ;
Bawa, Aditi (University of Pittsburgh Medical Center) ;
Hernández, Anjara (Hospital Universitario de Canarias (La Laguna)) ;
Pujol, Claudia (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Alvarado-Tapias, Edilmar (Institut d'Investigació Biomèdica Sant Pau) ;
Szafranska, Justyna (Institut d'Investigació Biomèdica Sant Pau) ;
Chiu, Wai Kan (University of Pittsburgh Medical Center) ;
Villagrasa, Ares (Hospital Universitari Vall d'Hebron) ;
Ventura-Cots, Meritxell (Hospital Universitari Vall d'Hebron) ;
Gandicheruvu, Haritha (University of Pittsburgh Medical Center) ;
Lluch, Paloma (Institut d'Investigació Biomèdica (INCLIVA)) ;
Chen, Hui-Wei (Allegheny General Hospital) ;
Rachakonda, Vikrant (University of California) ;
Duarte-Rojo, Andres (University of Pittsburgh Medical Center) ;
Bataller, Ramon (Hospital Clínic i Provincial de Barcelona) ;
Universitat Autònoma de Barcelona
The prevalence and impact of alcohol withdrawal syndrome (AWS) in patients with alcohol-associated hepatitis (AH) are unknown. In this study, we aimed to investigate the prevalence, predictors, management, and clinical impact of AWS in patients hospitalized with AH. [...]
2023 - 10.1016/j.eclinm.2023.102046
EClinicalMedicine, Vol. 61 (june 2023)
|
|
|
6.
|
|
14 p, 836.1 KB |
Predictive performance of interferon-gamma release assays and the tuberculin skin test for incident tuberculosis : an individual participant data meta-analysis
/
Hamada, Yohhei (University College London) ;
Gupta, Rishi K. (University College London) ;
Quartagno, Matteo (MRC Clinical Trials Unit) ;
Izzard, Abbie (University College London) ;
Acuna-Villaorduna, Carlos (Boston University Medical Center) ;
Altet, Neus (Unitat de TDO de la Tuberculosis 'Servicios Clínicos' (Espanya)) ;
Diel, Roland (Universitätsklinikum Schleswig-Holstein (Alemanya)) ;
Domínguez, José (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Floyd, Sian (London School of Hygiene & Tropical Medicine) ;
Gupta, Amita (Johns Hopkins University School of Medicine) ;
Huerga, Helena (Epicentre (França)) ;
Jones-López, Edward C. (University of Southern California) ;
Kinikar, Aarti (Sassoon General Hospital (India)) ;
Lange, Christoph (Tuberculosis Network European Trials Group (Alemanya)) ;
van Leth, Frank (Amsterdam Public Health Research Institute) ;
Liu, Qiao (Center for Disease Control and Prevention of Jiangsu Province) ;
Lu, Wei (Center for Disease Control and Prevention of Jiangsu Province) ;
Lu, Peng (Center for Disease Control and Prevention of Jiangsu Province) ;
Rueda, Irene Latorre (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Martinez, Leonardo (Boston University) ;
Mbandi, Stanley Kimbung (South African Tuberculosis Vaccine Initiative) ;
Muñoz, Laura (Universitat de Barcelona) ;
Padilla, Elisabeth Sánchez (Epicentre (França)) ;
Paradkar, Mandar (Johns Hopkins India (India)) ;
Scriba, Thomas (South African Tuberculosis Vaccine Initiative) ;
Sester, Martina (Saarland University) ;
Shanaube, Kwame (Zambart, Zambia) ;
Sharma, Surendra K. (Datta Meghe Institute of Medical Sciences (India)) ;
Sloot, Rosa (Stellenbosch University (Sud Àfrica)) ;
Sotgiu, Giovanni (University of Sassari) ;
Thiruvengadam, Kannan (Indian Council of Medical Research) ;
Vashishtha, Richa (All India Institute of Medical Sciences (Nova Delhi, Índia)) ;
Abubakar, Ibrahim (University College London) ;
Rangaka, Molebogeng X. (University of Cape Town) ;
Universitat Autònoma de Barcelona
Aquest document està subjecte a una llicència d'ús Creative Commons. Es permet la reproducció total o parcial, la distribució, la comunicació pública de l'obra i la creació d'obres derivades, fins i tot amb finalitats comercials, sempre i quan es reconegui l'autoria de l'obra original.
Evidence on the comparative performance of purified protein derivative tuberculin skin tests (TST) and interferon-gamma release assays (IGRA) for predicting incident active tuberculosis (TB) remains conflicting. [...]
2023 - 10.1016/j.eclinm.2022.101815
EClinicalMedicine, Vol. 56 (january 2023)
|
|
|
7.
|
|
13 p, 653.0 KB |
Subcutaneous anti-COVID-19 hyperimmune immunoglobulin for prevention of disease in asymptomatic individuals with SARS-CoV-2 infection : a double-blind, placebo-controlled, randomised clinical trial
/
Alemany, Andrea (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Millat-Martinez, Pere (Hospital Clínic i Provincial de Barcelona) ;
Corbacho-Monné, Marc (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Suñer, Clara (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Galván-Casas, Cristina (Hospital Universitario de Móstoles (Madrid)) ;
Carrera, Caty (Institut Català de la Salut) ;
Ouchi, Dan (Universitat Autònoma de Barcelona) ;
Prat, Núria (Institut Català de la Salut) ;
Ara del Rey, Jordi (Institut Català de la Salut) ;
Nadal, Nuria (Institut Català de la Salut) ;
Riel, Ricard (Institut Català de la Salut) ;
Funollet, Blanca (Institut Català de la Salut) ;
Ojeda-Ciurana, Carmen (Institut Català de la Salut) ;
Balague, Lluis Esteve (Institut Català de la Salut) ;
Salvador-González, Betlem (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Forcada Arcarons, Anna (Institut Català de la Salut) ;
Vidal-Alaball, Josep (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Del Cura-González, María Isabel (Red de Investigación en Cronicidad, Atención Primaria y Prevención y Promoción de la Salud) ;
Barrientos, Ricardo Rodríguez (Red de Investigación en Cronicidad, Atención Primaria y Promoción de la Salud) ;
Ramos, Rafel (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Bou, Alberto Alum (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Mondou, Elsa (Grifols (Barcelona, Catalunya)) ;
Torres, Mireia (Grifols (Barcelona, Catalunya)) ;
Campins, Neus (Grifols (Barcelona, Catalunya)) ;
Sanz, Ana (Grifols (Barcelona, Catalunya)) ;
Tang, Yonggiang (Grifols (Barcelona, Catalunya)) ;
Rodriguez-Arias, Miquel Àngel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Bassat, Quique (Hospital Clínic i Provincial de Barcelona) ;
Clotet Sala, Bonaventura (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Mitjà, Oriol (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
Anti-COVID-19 hyperimmune immunoglobulin (hIG) can provide standardized and controlled antibody content. Data from controlled clinical trials using hIG for the prevention or treatment of COVID-19 outpatients have not been reported. [...]
2023 - 10.1016/j.eclinm.2023.101898
EClinicalMedicine, Vol. 57 (march 2023)
|
|
|
8.
|
|
11 p, 1.2 MB |
A randomised, placebo-controlled phase 3 study to evaluate the efficacy and safety of ASP0113, a DNA-based CMV vaccine, in seropositive allogeneic haematopoietic cell transplant recipients
/
Ljungman, Per (Karolinska Institutet (Estocolm, Suècia)) ;
Bermúdez, Arancha (Instituto de Investigación Sanitaria Valdecilla (Santander, Cantàbria)) ;
Logan, Aaron C. (Division of Hematology and Blood and Marrow Transplantation. Department of Medicine. University of California) ;
Kharfan-Dabaja, Mohamed A. (Department of Blood and Marrow Transplantation. H. Lee Moffitt Cancer Center and Research Institute and University of South Florida) ;
Chevallier, Patrice (Service d'Hématologie Clinique. CHU de Nantes. 44093. Nantes. France and CRCINA / INSERM UMR1232 / CNRS ERL6001 IRS UN - 8) ;
Martino Bofarull, Rodrigo (Institut d'Investigació Biomèdica Sant Pau) ;
Wulf, Gerald (Department of Hematology and Medical Oncology. University Medical Center Göttingen) ;
Selleslag, Dominik (Department of Hematology. AZ Sint-Jan Brugge-Oostende) ;
Kakihana, Kazuhiko (Hematology Division. Tokyo Metropolitan Komagome Hospital) ;
Langston, Amelia (Winship Cancer Institute. Emory University) ;
Lee, Dong-Gun. (Division of Infectious Diseases. Department of Internal Medicine. Catholic Hematology Hospital and Seoul St. Mary's Hospital. College of Medicine. The Catholic University of Korea) ;
Solano, Carlos (Instituto de Investigación Sanitaria INCLIVA (València, Comunitat Valenciana)) ;
Okamoto, Shinichiro (Division of Hematology. Department of Medicine. Kelo University School of Medicine) ;
Smith, Larry R. (Vical) ;
Boeckh, Michael (Vaccine and Infectious Disease Division. Fred Hutchinson Cancer Research Center and University of Washington) ;
Wingard, John Reid (Division of Hematology & Oncology. Department of Medicine. University of Florida) ;
Cywin, Beth (Astellas Pharma Global Development) ;
Fredericks, Christine (Astellas Pharma Global Development) ;
Lademacher, Christopher (Astellas Pharma Global Development) ;
Wang, Xuegong (Astellas Pharma Global Development) ;
Young, James (Astellas Pharma Global Development) ;
Maertens, Johan (K.U. Leuven and Department of Hematology)
Background: Cytomegalovirus (CMV) is a complication of allogeneic haematopoietic cell transplantation (allo-HCT). ASP0113, a DNA-based vaccine, contains two plasmids encoding human CMV glycoprotein B and phosphoprotein 65 (pp65). [...]
2021 - 10.1016/j.eclinm.2021.100787
EClinicalMedicine, Vol. 33 (march 2021) , p. 100787
|
|
|
9.
|
|
12 p, 844.6 KB |
Epigenetic profiling linked to multisystem inflammatory syndrome in children (MIS-C) : A multicenter, retrospective study
/
Davalos, Veronica (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
García-Prieto, Carlos A (Barcelona Supercomputing Center) ;
Ferrer, Gerardo (Centro de Investigación Biomédica en Red de Cáncer) ;
Aguilera-Albesa, Sergio (Complejo Hospitalario de Navarra) ;
Valencia-Ramos, Juan (Hospital Universitario de Burgos) ;
Rodríguez-Palmero, Agustí (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Ruiz, Montserrat (Centro de Investigación Biomédica en Red de Enfermedades Raras) ;
Planas-Serra, Laura (Centro de Investigación Biomédica en Red de Enfermedades Raras) ;
Jordán García, Iolanda (Hospital Sant Joan de Déu (Barcelona, Catalunya)) ;
Alegría, Iosune (Complejo Hospitalario de Navarra) ;
Flores-Pérez, Patricia (Pediatrics Department. Hospital Universitario Niño Jesús) ;
Cantarín, Verónica (Pediatrics Department. Hospital Universitario Niño Jesús) ;
Fumadó, Victoria (Unitat de Malalties Infeccioses i Importades. Servei de Pediatría. Infectious and Imported Diseases. Pediatric Unit. Hospital Universitari Sant Joan de Deú) ;
Viadero, Maria Teresa (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ;
Rodrigo, Carlos (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Méndez-Hernández, Maria (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
López-Granados, Eduardo (Instituto de Investigación Sanitaria del Hospital Universitario La Paz) ;
Colobrán Oriol, Roger (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Rivière, Jacques G.. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Soler-Palacín, Pere (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Pujol, Aurora 1968- (Institució Catalana de Recerca i Estudis Avançats) ;
Esteller, M (Universitat de Barcelona. Departament de Ciències Fisiològiques) ;
Universitat Autònoma de Barcelona.
Departament de Pediatria, d'Obstetrícia i Ginecologia i de Medicina Preventiva
Background: Most children and adolescents infected with the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) remain asymptomatic or develop a mild coronavirus disease 2019 (COVID-19) that usually does not require medical intervention. [...]
2022 - 10.1016/j.eclinm.2022.101515
EClinicalMedicine, Vol. 50 (august 2022) , art. 101515
|
|
|
10.
|
|
visitante ::
identificación
alerta personal vía correo electrónico o subscríbase al 
canal RSS.
