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30 p, 1.2 MB Monoaminergic descending pathways contribute to modulation of neuropathic pain by increasing-intensity treadmill exercise after peripheral nerve injury / López-Álvarez, Víctor M. (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Puigdomenech Poch, Maria (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Navarro, X. (Xavier) (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Cobianchi, Stefano (Universitat Autònoma de Barcelona. Institut de Neurociències)
This study characterizes the impact of increasing-intensity treadmill exercise (iTR) on noradrenergic (NE) and serotonergic (5HT) modulation of neuropathic pain. Following sciatic nerve transection and repair (SNTR) rats developed significant mechanical and thermal hyperalgesia that was partially prevented by iTR performed during the first 2 weeks after injury. [...]
2018 - 10.1016/j.expneurol.2017.10.007
Experimental Neurology, Vol. 299, Part A (January 2018) , p. 42-55  

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