Dipòsit Digital de Documents de la UAB 10 registres trobats  La cerca s'ha fet en 0.01 segons. 
1.
7 p, 933.0 KB The repertoires of peptides presented by MHC-II in the thymus and in peripheral tissue : A clue for autoimmunity? / Collado Miguens, Javier Alonso (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Guitart, Carolina (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Ciudad García, María Teresa (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Alvarez Pérez, Ignacio Gerardo (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Jaraquemada, Dolores (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí"
T-cell tolerance to self-antigens is established in the thymus through the recognition by developing thymocytes of self-peptide-MHC complexes and induced and maintained in the periphery. Efficient negative selection of auto-reactive T cells in the thymus is dependent on the in situ expression of both ubiquitous and tissue-restricted self-antigens and on the presentation of derived peptides. [...]
2013 - 10.3389/fimmu.2013.00442
Frontiers in Immunology, Vol. 4 (December 2013) , art. 442  
2.
15 p, 2.0 MB Monitoring t-cell responses in translational studies: optimization of Dye-Based Proliferation Assay for Evaluation of Antigen-specific responses / Brinke, Anja ten (Sanquin Research (Amsterdam)) ; Marek-Trzonkowska,Natalia (Medical University of Gdansk. Department of Family Medicine) ; Mansilla, Maria J. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Turksma, Annelies W. (Sanquin Research (Amsterdam)) ; Piekarska, Karolina (Medical University of Gdansk. Department of Family Medicine) ; Iwaszkiewicz-Grzes, Dorota (Medical University of Gdansk. Department of Clinical Immunology and Transplantology) ; Passerini, Laura (IRCCS San Raffaele Scientific Institute) ; Locafaro, Grazia (IRCCS San Raffaele Scientific Institute) ; Puñet Ortiz, Joan (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; van Ham, S. Marieke (Sanquin Research (Amsterdam)) ; Hernandez Fuentes, Maria P. (MRC Centre for Transplantation, King's College London) ; Martínez Cáceres, Eva M. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Gregori, Silvia (IRCCS San Raffaele Scientific Institute) ; Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia
Adoptive therapy with regulatory T cells or tolerance-inducing antigen (Ag)- presenting cells is innovative and promising therapeutic approach to control undesired and harmful activation of the immune system, as observed in autoimmune diseases, solid organ and bone marrow transplantation. [...]
2017
Frontiers in immunology, Vol. 8 (december 2017) , p. 1-15  
3.
13 p, 6.0 MB Mesenchymal stem cells induce expression of cD73 in human monocytes in vitro and in a swine model of myocardial infarction in vivo / Monguió-Tortajada, Marta (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Roura, Santiago (Institut Germans Trias i Pujol) ; Gálvez-Montón, Carolina (Institut Germans Trias i Pujol) ; Franquesa, Marcella (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Bayes-Genis, Antoni (Universitat Autònoma de Barcelona. Departament de Medicina) ; Borràs,Francesc E. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, Fisiologia i Immunologia)
The ectoenzymes CD39 and CD73 regulate the purinergic signaling through the hydrolysis of adenosine triphosphate (ATP)/ADP to AMP and to adenosine (Ado), respectively. This shifts the pro-inflammatory milieu induced by extracellular ATP to the anti- inflammatory regulation by Ado. [...]
2017 - 10.3389/fimmu.2017.01577
Frontiers in immunology, Vol. 8 (november 2017) , p. 1-13  
4.
15 p, 5.9 MB Prenatal administration of Betamethasone causes changes in the T cell receptor repertoire influencing Development of autoimmunity / Gieras, Anna (University Medical Center Hamburg-Eppendorf. Department of Immunology) ; Gehbauer, Christina (University Medical Center Hamburg-Eppendorf. Department of Immunology) ; Perna-Barrull, David (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Engler, Jan Broder (Institute of Neuroimmunology and Multiple Sclerosis. Center for Molecular Neurobiology Hamburg) ; Diepenbruck, Ines (University Medical Center Hamburg-Eppendorf. Department of Immunology) ; Glau, Laura (University Medical Center Hamburg-Eppendorf. Department of Immunology) ; Joosse, Simon A. (University Medical Center Hamburg-Eppendorf. Department of Tumor Biology) ; Kersten, Nora (University Medical Center Hamburg-Eppendorf. Department of Immunology) ; Klinge, Stefanie (University Medical Center Hamburg-Eppendorf. Department of Immunology) ; Mittrücker, Hans-Willi (University Medical Center Hamburg-Eppendorf. Department of Immunology) ; Friese, Manuel A. (Institute of Neuroimmunology and Multiple Sclerosis, Center for Molecular Neurobiology Hamburg) ; Vives-Pi, Marta (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Tolosa, Eva (University Medical Center Hamburg-Eppendorf. Department of Immunology) ; Universitat Autònoma de Barcelona
Prenatal glucocorticoids are routinely administered to pregnant women at risk of preterm delivery in order to improve survival of the newborn. However, in half of the cases, birth occurs outside the beneficial period for lung development. [...]
2017 - 10.3389/fimmu.2017.01505
Frontiers in immunology, Vol. 8 (november 2017) , p. 1-15  
5.
13 p, 6.6 MB Inflammatory conditions dictate the effect of Mesenchymal stem or Stromal cells on B cell function. / Luk, Franka (Erasmus University Medical Center, Rotterdam) ; Carreras-Planella, Laura (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Korevaar, Sander S. (Erasmus University Medical Center, Rotterdam) ; de Witte, Samantha F. H. (Erasmus University Medical Center, Rotterdam) ; Borràs, Francesc E. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, Fisiologia i Immunologia) ; Betjes, Michiel G. H. (Erasmus University Medical Center, Rotterdam) ; Baan, Carla C. (Erasmus University Medical Center, Rotterdam) ; Hoogduijn, Martin J. (Erasmus University Medical Center, Rotterdam) ; Franquesa, Marcella (Erasmus University Medical Center, Rotterdam)
The immunomodulatory capacity of mesenchymal stem or stromal cells (MSC) makes them a promising tool for treatment of immune disease and organ transplantation. The effects of MSC on B cells are characterized by an abrogation of plasmablast formation and induction of regulatory B cells (Bregs). [...]
2017 - 10.3389/fimmu.2017.01042
Frontiers in immunology, Vol. 8 (august 2017) , p. 1-13  
6.
11 p, 2.1 MB What we have learned and what we have missed in tuberculosis pathophysiology fos a new vaccine design: searching for the "pink swan" / Cardona, Pere-Joan (Institut Germans Trias i Pujol) ; Universitat Autònoma de Barcelona
This is a call to encourage the search for a new vaccine to stop the progression of Mycobacterium tuberculosis infection to tuberculosis (TB) disease. TB is a highly discreet and stigmatized disease, with a massive impact on human health. [...]
2017 - 10.3389/fimmu.2017.00556
Frontiers in Immunology, Vol. 8 Núm. 556 (may 2017) , p. 1-11  
7.
12 p, 4.0 MB Protein nanoparticles Made of recombinant Viral antigens : A Promising Biomaterial for Oral Delivery of Fish Prophylactics / Thwaite, Rosemary (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Jie, Ji (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Torrealba, Debora (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Coll, Julio (Instituto Nacional Investigaciones y Tecnologías Agrarias y Alimentarias (INIA), Departamento de Biotecnología) ; Sabés i Xamaní, Manel, dir. (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Villaverde, Antonio (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Roher, Nerea (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
In the search for an eminently practical strategy to develop immunostimulants and vaccines for farmed fish, we have devised recombinant viral antigens presented as “nanopellets" (NPs). These are inclusion bodies of fish viral antigenic proteins produced in Escherichia coli. [...]
2018 - 10.3389/fimmu.2018.01652
Frontiers in Immunology, Vol. doi: 10.33 (2018)  
8.
17 p, 2.4 MB Phosphatidylserine-liposomes promote tolerogenic features on dendritic cells in human type 1 diabetes by apoptotic mimicry / Rodriguez Fernandez, Silvia (Institut Germans Trias i Pujol) ; Pujol-Autonell, Irma (Institut Germans Trias i Pujol) ; Brianso, Ferran (Universitat de Barcelona. Departament de Genètica, Microbiologia i Estadística) ; Perna Barrull, David (Institut Germans Trias i Pujol) ; Cano Sarabia, Antonia María (Institut Català de Nanociència i Nanotecnologia) ; Garcia Jimeno, Sonia (Institut Català de Nanociència i Nanotecnologia) ; Villalba Felipe, Adrián (Institut Germans Trias i Pujol) ; Sanchez, Alex (Universitat de Barcelona. Departament de Genètica, Microbiologia i Estadística) ; Aguilera, Eva (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Vazquez, Federico (Hospital Universitari Germans Trias i Pujol. Servei d'Endocrinologia) ; Verdaguer, Joan (Universitat de Lleida. Departament de Medicina Experimental) ; Maspoch Comamala, Daniel (Institució Catalana de Recerca i Estudis Avançats) ; Vives-Pi, Marta (Institut Germans Trias i Pujol)
Type 1 diabetes (T1D) is a metabolic disease caused by the autoimmune destruction of insulin-producing β-cells. With its incidence increasing worldwide, to find a safe approach to permanently cease autoimmunity and allow β-cell recovery has become vital. [...]
2018 - 10.3389/fimmu.2018.00253
Frontiers in immunology, Vol. 9 (Feb. 2018) , art. 253  
9.
12 p, 2.4 MB Mucosal Immunity and B Cells in Teleosts : Effect of Vaccination and Stress / Parra, David (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia. Àrea de Fisiologia) ; Reyes-Lopez, Felipe E. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia. Àrea de Fisiologia) ; Tort, Lluis (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia. Àrea de Fisiologia)
Fish are subjected to several insults from the environment, which may endanger animal survival. Mucosal surfaces are the first line of defense against these threats, acting as a physical barrier to protect the animal but also functioning as an active immune tissue. [...]
2015 - 10.3389/fimmu.2015.00354
Frontiers in Immunology, Vol. 6 (july 2015)  
10.
12 p, 984.2 KB Human leukocyte antigen (HLA)-DRB1*15:01 and HLA-DRB5*01:01 present complementary peptide repertoires / Scholz, Erika Margaret (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Marcilla, Miguel (Centro Nacional de Biotecnología (Espanya). Unidad de Proteómica) ; Daura i Ribera, Xavier (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Arribas-Layton, David (Benaroya Research Institute at Virginia Mason) ; James, Eddie A. (Benaroya Research Institute at Virginia Mason) ; Álvarez, Iñaki (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia. Unitat de Fisiologia)
Human leukocyte antigen (HLA)-DR15 is a haplotype associated with multiple sclerosis. It contains the two DRB* genes DRB1*1501 (DR2b) and DRB5*0101 (DR2a). The reported anchor motif of the corresponding HLA-DR molecules was determined in 1994 based on a small number of peptide ligands and binding assays. [...]
2017 - 10.3389/fimmu.2017.00984
Frontiers in immunology, Vol. 8 (Aug. 2017) , art. 984  

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