UAB Digital Repository of Documents 51 records found  1 - 10nextend  jump to record: Search took 0.01 seconds. 
1.
20 p, 1.6 MB Immune Dysregulation and the Increased Risk of Complications and Mortality Following Respiratory Tract Infections in Adults With Down Syndrome / Illouz, Tomer (Bar-Ilan University) ; Biragyn, Arya (National Institute on Aging, National Institute of Health, Baltimore) ; Iulita, M. Florencia (Institut d'Investigació Biomèdica Sant Pau) ; Flores-Aguilar, Lisi (McGill University) ; Dierssen, Mara (Centro de Investigación Biomédica en Red de Enfermedades Raras) ; De Toma, Ilario (Centro de Investigación Biomédica en Red de Enfermedades Raras) ; Antonarakis, Stylianos E. (iGE3 Institute of Genetics and Genomics of Geneva) ; Yu, Eugene (State University of New York at Buffalo) ; Herault, Yann (Université de Strasbourg) ; Potier, Marie-Claude (Paris Brain Institute (ICM)) ; Botté, Alexandra (Paris Brain Institute (ICM)) ; Roper, Randall (Indiana University-Purdue University Indianapolis) ; Sredni, Benjamin (Bar-Ilan University) ; London, Jacqueline (Université de Paris) ; Mobley, William (University of California, San Diego) ; Strydom, Andre (South London and Maudsley NHS Foundation Trust) ; Okun, Eitan (Bar-Ilan University) ; Universitat Autònoma de Barcelona
The risk of severe outcomes following respiratory tract infections is significantly increased in individuals over 60 years, especially in those with chronic medical conditions, i. e. , hypertension, diabetes, cardiovascular disease, dementia, chronic respiratory disease, and cancer. [...]
2021 - 10.3389/fimmu.2021.621440
Frontiers in immunology, Vol. 12 (june 2021)  
2.
15 p, 16.2 MB Interaction of Type 1 Porcine Reproductive and Respiratory Syndrome Virus With In Vitro Derived Conventional Dendritic Cells / Li, Yanli (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals) ; Mateu de Antonio, Enrique María (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal)
The present study delineates the interaction of a typical PRRSV1. 1 isolate 3267 (moderate virulence) with in vitro derived pig conventional dendritic cells, cDC1, cDC2, and a CD14 + population (designated as CD14 + DCs). [...]
2021 - 10.3389/fimmu.2021.674185
Frontiers in immunology, Vol. 12 (june 2021)  
3.
4 p, 256.4 KB Hemadsorption as a Treatment Option for Multisystem Inflammatory Syndrome in Children Associated With COVID-19. A Case Report / Ruiz-Rodríguez, Juan Carlos (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Chiscano-Camón, Luis (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Palmada, Clara (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Ruiz-Sanmartin, Adolf (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; García-de-Acilu, Marina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Plata-Menchaca, Erika (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Perurena-Prieto, Janire (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Hernandez-Gonzalez, Manuel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Pérez-Carrasco, Marcos (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Soler-Palacin, Pere (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Ferrer, Ricard (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Universitat Autònoma de Barcelona
Multisystem Inflammatory Syndrome in Children (MIS-C) associated with COVID-19 is characterized by hypercytokinemia leading to overwhelming inflammation. We describe the use of a hemadsorption device as part of the supportive treatment for cytokine storm.
2021 - 10.3389/fimmu.2021.665824
Frontiers in immunology, Vol. 12 (june 2021)  
4.
8 p, 3.5 MB Evaluation of the Immune Response Induced by CoronaVac 28-Day Schedule Vaccination in a Healthy Population Group / Escobar, Alejandro (Universidad de Chile. Instituto de Investigación en Ciencias Odontológicas) ; Reyes-López, Felipe E. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Acevedo, Mónica L. (Universidad de Chile. Institute of Biomedical Sciences) ; Alonso-Palomares, Luis (Universidad de Chile. Institute of Biomedical Sciences) ; Valiente-Echeverría, Fernando (Universidad de Chile. Institute of Biomedical Sciences) ; Soto-Rifo, Ricardo (Universidad de Chile. Institute of Biomedical Sciences) ; Portillo, Hugo (Universidad de Chile. Instituto de Investigación en Ciencias Odontológicas) ; Gatica, Jimena (Universidad de Chile. Instituto de Investigación en Ciencias Odontológicas) ; Flores, Ivan (Universidad de Chile. Instituto de Investigación en Ciencias Odontológicas) ; Nova-Lamperti, Estefanía (University of Concepcion. Department of Clinical Biochemistry and Immunology) ; Barrera-Avalos, Carlos (Universidad de Santiago de Chile. Centro de Biotecnología Acuícola) ; Bono, María Rosa (Universidad de Chile. Departamento de Biología) ; Vargas, Leonardo (Universidad de Chile. Departamento de Biología) ; Simon, Valeska (Universidad de Chile. Departamento de Biología) ; Leiva-Salcedo, Elias (Universidad de Santiago de Chile. Centro de Biotecnología Acuícola) ; Vial, Cecilia (Clínica Alemana Universidad del Desarrollo. Instituto de Ciencias e Innovación en Medicina) ; Hormazabal, Juan (Clínica Alemana Universidad del Desarrollo. Instituto de Ciencias e Innovación en Medicina) ; Cortes, Lina Jimena (Clínica Alemana Universidad del Desarrollo. Instituto de Ciencias e Innovación en Medicina) ; Valdés, Daniel (Universidad de Santiago de Chile. Centro de Biotecnología Acuícola) ; Sandino, Ana María (Universidad de Santiago de Chile. Centro de Biotecnología Acuícola) ; Imarai, Mónica (Universidad de Santiago de Chile. Centro de Biotecnología Acuícola) ; Acuña-Castillo, Claudio (Universidad de Santiago de Chile. Centro de Biotecnología Acuícola)
CoronaVac vaccine from Sinovac Life Science is currently being used in several countries. In Chile, the effectiveness of preventing hospitalization is higher than 80% with a vaccination schedule. However, to date, there are no data about immune response induction or specific memory. [...]
2022 - 10.3389/fimmu.2021.766278
Frontiers in immunology, Vol. 12 (january 2022)  
5.
5 p, 380.6 KB Anti-TIF-1γ Antibody Detection Using a Commercial Kit vs In-House Immunoblot : Usefulness in Clinical Practice / Mariscal, Anaís (Institut d'Investigació Biomèdica Sant Pau) ; Milán, Milena (Institut d'Investigació Biomèdica Sant Pau) ; Baucells, Andrés (Institut d'Investigació Biomèdica Sant Pau) ; Martínez, Maria Angeles (Institut d'Investigació Biomèdica Sant Pau) ; Guillen, Andrea Garcia (Institut d'Investigació Biomèdica Sant Pau) ; Trallero-Araguás, Ernesto (Hospital Universitari Vall d'Hebron) ; Alvarado-Cardenas, Marcelo (Hospital Universitari Vall d'Hebron) ; Martinez-Martinez, Laura (Institut d'Investigació Biomèdica Sant Pau) ; Alserawan, Leticia (Institut d'Investigació Biomèdica Sant Pau) ; Franco-Leyva, Teresa (Institut d'Investigació Biomèdica Sant Pau) ; Sanz-Martínez, María Teresa (Hospital Universitari Vall d'Hebron) ; Viñas-Giménez, Laura (Hospital Universitari Vall d'Hebron) ; Corominas, Hèctor (Institut d'Investigació Biomèdica Sant Pau) ; Juarez, Candido (Institut d'Investigació Biomèdica Sant Pau) ; Castellvi, Ivan (Institut d'Investigació Biomèdica Sant Pau) ; Selva O'Callaghan, Albert (Hospital Universitari Vall d'Hebron) ; Universitat Autònoma de Barcelona
Anti-TIF-1γ autoantibody detection is important for cancer screening in patients with dermatomyositis. The gold standard for anti-TIF-1γ detection, immunoprecipitation, is only available from a few specialized laboratories worldwide, so commercial ELISA/immunoblot tests have emerged in recent years. [...]
2021 - 10.3389/fimmu.2020.625896
Frontiers in immunology, Vol. 11 (february 2021)  
6.
794.3 KB Searching for the Transcriptomic Signature of Immune Tolerance Induction-Biomarkers of Safety and Functionality for Tolerogenic Dendritic Cells and Regulatory Macrophages / Navarro-Barriuso, Juan (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Mansilla, María José (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Martínez-Cáceres, Eva M. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol)
The last years have witnessed a breakthrough in the development of cell-based tolerance-inducing cell therapies for the treatment of autoimmune diseases and solid-organ transplantation. Indeed, the use of tolerogenic dendritic cells (tolDC) and regulatory macrophages (Mreg) is currently being tested in Phase I and Phase II clinical trials worldwide, with the aim of finding an effective therapy able to abrogate the inflammatory processes causing these pathologies without compromising the protective immunity of the patients. [...]
2018 - 10.3389/fimmu.2018.02062
Frontiers in immunology, Vol. 9 (september 2018)  
7.
17 p, 8.0 MB Genomic Multiple Sclerosis Risk Variants Modulate the Expression of the ANKRD55 - IL6ST Gene Region in Immature Dendritic Cells / Mena, Jorge (Instituto de Investigación Sanitaria Biocruces Bizkaia) ; Alloza, Iraide (Instituto de Investigación Sanitaria Biocruces Bizkaia) ; Tulloch Navarro, Raquel (Instituto de Investigación Sanitaria Biocruces Bizkaia) ; Aldekoa, Ane (Instituto de Investigación Sanitaria Biocruces Bizkaia) ; Díez García, Javier (Biocruces-Bizkaia Health Research Institute) ; Villanueva Etxebarria, Ane (Hospital de Galdakao (Biscaia)) ; Lindskog, Cecilia (Uppsala University) ; Antigüedad, Alfredo (Instituto de Investigación Sanitaria Biocruces Bizkaia) ; Boyero, Sabas (Instituto de Investigación Sanitaria Biocruces Bizkaia) ; Mendibe-Bilbao, María del Mar (Instituto de Investigación Sanitaria Biocruces Bizkaia) ; Álvarez de Arcaya, Amaya (Instituto de Investigación Sanitaria Bioaraba (País Basc)) ; Sánchez Menoyo, José Luis (Instituto de Investigación Sanitaria Biocruces Bizkaia) ; Midaglia, Luciana (Hospital Universitari Vall d'Hebron) ; Villarrubia, Noelia (Instituto Ramón y Cajal de Investigación Sanitaria (Madrid)) ; Malhotra, Sunny (Hospital Universitari Vall d'Hebron) ; Montalban, Xavier (Hospital Universitari Vall d'Hebron) ; Villar, Luisa María (Instituto Ramón y Cajal de Investigación Sanitaria (Madrid)) ; Comabella, Manuel (Hospital Universitari Vall d'Hebron) ; Vandenbroeck, Koen (Basque Foundation for Science) ; Universitat Autònoma de Barcelona
Intronic single-nucleotide polymorphisms (SNPs) in the ANKRD55 gene are associated with the risk for multiple sclerosis (MS) and rheumatoid arthritis by genome-wide association studies (GWAS). The risk alleles have been linked to higher expression levels of ANKRD55 and the neighboring IL6ST (gp130) gene in CD4 + T lymphocytes of healthy controls. [...]
2022 - 10.3389/fimmu.2021.816930
Frontiers in immunology, Vol. 12 (january 2022)  
8.
11 p, 1.8 MB CDK11 Promotes Cytokine-Induced Apoptosis in Pancreatic Beta Cells Independently of Glucose Concentration and Is Regulated by Inflammation in the NOD Mouse Model / Sala, Ester (Institut de Recerca Biomèdica de Lleida) ; Vived, Celia (Institut de Recerca Biomèdica de Lleida) ; Luna, Júlia (Institut de Recerca Biomèdica de Lleida) ; Saavedra-Ávila, Noemí Alejandra (Institut de Recerca Biomèdica de Lleida) ; Sengupta, Upasana (Institut de Recerca Biomèdica de Lleida) ; Castaño, A. Raúl (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Villar-Pazos, Sabrina (St. Jude Children's Research Hospital) ; Haba, Laura (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Verdaguer, Joan (Institut de Recerca Biomèdica de Lleida) ; Ropero, Ana B. (Instituto de Bioingeniería, Universidad Miguel Hernández) ; Stratmann, Thomas (Universitat de Barcelona. Departament de Biologia Cel·lular, Fisiologia i Immunologia) ; Pizarro, Javier (Hospital Sant Joan de Déu (Manresa)) ; Vázquez-Carrera, Manuel (Hospital Sant Joan de Déu (Manresa)) ; Nadal, Angel (Universidad Miguel Hernández de Elche) ; Lahti, Jill M. (St. Jude Children's Research Hospital) ; Mora, Conchi (Institut de Recerca Biomèdica de Lleida)
Pancreatic islets are exposed to strong pro-apoptotic stimuli: inflammation and hyperglycemia, during the progression of the autoimmune diabetes (T1D). We found that the Cdk11(Cyclin Dependent Kinase 11) is downregulated by inflammation in the T1D prone NOD (non-obese diabetic) mouse model. [...]
2021 - 10.3389/fimmu.2021.634797
Frontiers in immunology, Vol. 12 (February 2021)  
9.
11 p, 2.4 MB Acute Graft-vs.-Host Disease-Associated Endothelial Activation in vitro Is Prevented by Defibrotide / Martinez-Sanchez, Julia (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Hamelmann, H. (Berlin Institute of Health. Department of Hematology and Oncology) ; Palomo, Marta (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Mir, Enrique (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Moreno-Castaño, A.B. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Torramade, S. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Rovira, M. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Escolar, G. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Cordes, S. (Berlin Institute of Health. Department of Hematology and Oncology) ; Kalupa, M. (Berlin Institute of Health. Department of Hematology and Oncology) ; Mertlitz, S. (Berlin Institute of Health. Department of Hematology and Oncology) ; Riesner, K. (Berlin Institute of Health. Department of Hematology and Oncology) ; Carreras, Enric (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Penack, O. (Berlin Institute of Health. Department of Hematology and Oncology) ; Díaz-Ricart, Maribel (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Universitat Autònoma de Barcelona
Angiogenesis and endothelial activation and dysfunction have been associated with acute graft-vs. -host disease (aGVHD), pointing to the endothelium as a potential target for pharmacological intervention. [...]
2019 - 10.3389/fimmu.2019.02339
Frontiers in immunology, Vol. 10 (september 2019) , p. 2339  
10.
9 p, 742.8 KB The Genome in a Three-Dimensional Context : Deciphering the Contribution of Noncoding Mutations at Enhancers to Blood Cancer / Rovirosa Mulet, Llorenç (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Ramos-Morales, Alberto (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Javierre, BM (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Universitat Autònoma de Barcelona
Associations between blood cancer and genetic predisposition, including both inherited variants and acquired mutations and epimutations, have been well characterized. However, the majority of these variants affect noncoding regions, making their mechanisms difficult to hypothesize and hindering the translation of these insights into patient benefits. [...]
2020 - 10.3389/fimmu.2020.592087
Frontiers in immunology, Vol. 11 (july 2020) , p. 592087  

UAB Digital Repository of Documents : 51 records found   1 - 10nextend  jump to record:
Interested in being notified about new results for this query?
Set up a personal email alert or subscribe to the RSS feed.