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29 p, 401.7 KB |
Epigenetic targets in B- and T-cell lymphomas : latest developments
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Ribeiro, Marcelo L. (Sao Francisco University Medical School) ;
Sánchez Vinces, Salvador (Sao Francisco University Medical School) ;
Mondragón, Laura (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Roué, Gaël (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras)
Non-Hodgkin's lymphomas (NHLs) comprise a diverse group of diseases, either of mature B-cell or of T-cell derivation, characterized by heterogeneous molecular features and clinical manifestations. While most of the patients are responsive to standard chemotherapy, immunotherapy, radiation and/or stem cell transplantation, relapsed and/or refractory cases still have a dismal outcome. [...]
2023 -  10.1177/20406207231173485
Therapeutic Advances in Hematology, Vol. 14 (1-12 2023)
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10 p, 3.0 MB |
Applicability and validation of different prognostic scores in allogeneic hematopoietic cell transplant (HCT) in the post-transplant cyclophosphamide era
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Salas, María Queralt (Hospital Clínic i Provincial de Barcelona) ;
Rodríguez Lobato, Luis Gerardo (Hospital Clínic i Provincial de Barcelona) ;
Charry, Paola (Hospital Clínic i Provincial de Barcelona) ;
Suárez-Lledó, Maria (Hospital Clínic i Provincial de Barcelona) ;
Pedraza, Alexandra (Hospital Clínic i Provincial de Barcelona) ;
Solano, María Teresa (Hospital Clínic i Provincial de Barcelona) ;
Arcarons, Jordi (Hospital Clínic i Provincial de Barcelona) ;
Cid, Joan (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Lozano, Miquel (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Rosiñol, Laura (Hospital Clínic i Provincial de Barcelona) ;
Esteve, Jordi (Hospital Clínic i Provincial de Barcelona) ;
Carreras, Enric (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Fernandez Aviles, Francesc (Hospital Clínic i Provincial de Barcelona) ;
Martínez, Carmen (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Rovira Tarrats, Montserrat (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras)
We investigated the predictive capacity of six prognostic indices [Karnofsky Performance Status (KPS), Hematopoietic Cell Transplant-Specific Comorbidity Index (HCT-CI), Disease Risk Index (DRI), European Bone Marrow Transplantation (EBMT) and Revised Pre-Transplantation Assessment of Mortality (rPAM) Scores and Endothelial Activation and Stress Index (EASIX)] in 205 adults undergoing post-transplant cyclophosphamide (PTCy)-based allo-HCT. [...]
2023 - 10.1016/j.htct.2023.07.008
Hematology, Transfusion and Cell Therapy, 2023
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7 p, 660.3 KB |
Clinical characteristics of patients with central nervous system relapse in BCR-ABL1-positive acute lymphoblastic leukemia : the importance of characterizing ABL1 mutations in cerebrospinal fluid
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Sanchez, R. (Hospital 12 de Octubre (Madrid)) ;
Ayala, Rosa (Hospital 12 de Octubre (Madrid)) ;
Alonso, R.A. (Hospital 12 de Octubre (Madrid)) ;
Martínez, M.P. (Hospital 12 de Octubre (Madrid)) ;
Ribera, Jordi (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
García, Olga (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Sanchez-Pina, J. (Hospital 12 de Octubre (Madrid)) ;
Mercadal, S. (ICO-Hospital Duran i Reynals (Bellvitge)) ;
Montesinos, P. (Hospital Universitari i Politècnic La Fe de València) ;
Martino Bofarull, Rodrigo (Institut d'Investigació Biomèdica Sant Pau) ;
Barba, Pere (Hospital Universitari Vall d'Hebron) ;
González-Campos, J. (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Barrios, M. (Hospital Regional Universitario Carlos Haya (Málaga)) ;
Lavilla, E. (Hospital Universitario Lucus Augusti (Lugo)) ;
Gil, C. (Hospital General Universitario de Alicante (Alacant, País Valencià)) ;
Bernal, T. (Hospital Universitario Central de Asturias) ;
Escoda, L. (Hospital Universitari Joan XXIII de Tarragona) ;
Abella Monreal, Eugenia (Hospital del Mar (Barcelona, Catalunya)) ;
Amigo, María-Luz (Hospital General Universitario Morales Meseguer (Múrcia)) ;
Moreno, M.J. (Hospital Universitario Virgen de la Victoria (Màlaga, Andalusia)) ;
Bravo, P. (Hospital de Fuenlabrada) ;
Guàrdia, R. (Hospital Universitari de Girona Doctor Josep Trueta) ;
Hernández-Rivas, J.M. (Hospital Universitario de Salamanca) ;
García-Guiñón, A. (Hospital Universitari Arnau de Vilanova) ;
Piernas, Sonia (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Ribera, José Maria (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Martínez-López, J. (Hospital 12 de Octubre (Madrid)) ;
Universitat Autònoma de Barcelona
We investigated the frequency, predictors, and evolution of acute lymphoblastic leukemia (ALL) in patients with CNS relapse and introduced a novel method for studying BCR-ABL1 protein variants in cDNA from bone marrow (BM) and cerebrospinal fluid (CSF) blast cells. [...]
2017 - 10.1007/s00277-017-3002-1
Annals of Hematology, Vol. 96 Núm. 7 (january 2017) , p. 1069-1075
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The PML-RARA fusion is not detectable in historical blood samples of acute promyelocytic leukaemia patients
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Dunn, W.G. (Cambridge University Hospitals NHS Trust) ;
Nomdedeu, Josep (Institut d'Investigació Biomèdica Sant Pau) ;
Koumas, L. (Karaiskakio Foundation) ;
Nicolaou, K. (Karaiskakio Foundation) ;
Chi, J. (Karaiskakio Foundation) ;
Costeas, P. (Cyprus Cancer Research Institute) ;
Vassiliou, G.S. (Cyprus Cancer Research Institute) ;
Gu, M.S. (Wellcome Trust Sanger Institute (Regne Unit)) ;
Fabre, M.A. (Wellcome Trust Sanger Institute (Regne Unit)) ;
Cooper, J. (Wellcome Trust Sanger Institute (Regne Unit)) ;
Universitat Autònoma de Barcelona
2022 - 10.1007/s00277-021-04472-5
Annals of Hematology, Vol. 101 Núm. 2 (february 2022) , p. 443-445
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10 p, 786.4 KB |
Haploidentical transplantation is associated with better overall survival when compared to single cord blood transplantation : An EBMT-Eurocord study of acute leukemia patients conditioned with thiotepa, busulfan, and fludarabine
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Giannotti, Federica (Saint-Antoine Hospital) ;
Labopin, Myriam (Hôpital Saint-Antoine (Paris, França)) ;
Shouval, Roni (Chaim Sheba Medical Center (Israel)) ;
Sanz, Jaime (Instituto de Salud Carlos III) ;
Arcese, William (Rome Transplant Network tor Vergatä) ;
Angelucci, Emanuele (Ospedale Policlinico San Martino) ;
Malouf Sierra, Jorge 1971- (Institut d'Investigació Biomèdica Sant Pau) ;
Ribera, Jose-Maria (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Santarone, Stella (Ospedale Civile) ;
Benedetto, Bruno (S.S.C.V.D Trapianto di Cellule Staminali A.O.U Citta della Salute e della Scienza di Torino) ;
Rambaldi, Alessandro (Azienda Ospedaliera Papa Giovanni XXIII) ;
Saccardi, Riccardo (Azienda Ospedaliera Universitaria Careggi) ;
Blaise, Didier (Institut Paoli Calmettes) ;
Carella, Michele Angelo (IRCCS) ;
Rocha, Vanderson (Universidade de São Paulo) ;
Baron, Frederic (University of Liege) ;
Mohty, Mohamad (Hospital Saint- Antoine) ;
Ruggeri, Annalisa (Ospedale Pediatrico Bambino Gesù (Roma, Itàlia)) ;
Nagler, Arnon (Tel-Aviv University) ;
Universitat Autònoma de Barcelona
Thiotepa-busulfan-fludarabine (TBF) is a widely used conditioning regimen in single umbilical cord blood transplantation (SUCBT). More recently, it was introduced in the setting of non-T cell depleted haploidentical stem cell transplantation (NTD-Haplo). [...]
2018 - 10.1186/s13045-018-0655-8
Journal of hematology & oncology, Vol. 11 Núm. 1 (30 2018) , p. 110
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9 p, 1.3 MB |
Single-agent ibrutinib versus chemoimmunotherapy regimens for treatment-naïve patients with chronic lymphocytic leukemia : A cross-trial comparison of phase 3 studies
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Robak, Tadeusz (Medical University of Lodz) ;
Burger, Jan A. (The University of Texas MD Anderson Cancer Center) ;
Tedeschi, Alessandra (ASST Grande Ospedale Metropolitano Niguarda) ;
Barr, Paul M. (University of Rochester Cancer Center) ;
Owen, Carolyn (University of Calgary) ;
Bairey, Osnat (Tel Aviv University) ;
Hillmen, Peter (St. James's Institute of Oncology) ;
Simpson, David (North Shore Hospital) ;
Grosicki, Sebastian (Silesian Medical University) ;
Devereux, Stephen (King's College Hospital NHS Foundation Trust) ;
McCarthy, Helen (Royal Bournemouth Hospital) ;
Coutre, Steven E (Stanford University School of Medicine) ;
Quach, Hang (St. Vincent's Hospital) ;
Gaidano, Gianluca (Amedeo Avogadro University of Eastern Piedmont) ;
Maslyak, Zvenyslava (Institute of Blood Pathology and Transfusion Medicine of the Academy of Medical Sciences of Ukraine) ;
Stevens, Don A. (Norton Cancer Institute) ;
Moreno, Carol (Institut d'Investigació Biomèdica Sant Pau) ;
Gill, Devinder S. (Princess Alexandra Hospital) ;
Flinn, Ian W. (Sarah Cannon Research Institute/Tennessee Oncology) ;
Gribben, John G. (Queen Mary University of London) ;
Mokatrin, Ahmad (Pharmacyclics LLC. an AbbVie Company) ;
Cheng, Mei (Pharmacyclics LLC. an AbbVie Company) ;
Styles, Lori (Pharmacyclics LLC. an AbbVie Company) ;
James, Danelle F. (Pharmacyclics LLC. an AbbVie Company) ;
Kipps, Thomas J (University of California San Diego) ;
Ghia, Paolo (Università Vita-Salute San Raffaele and IRCCS Istituto Scientifico San Raffaele) ;
Universitat Autònoma de Barcelona
Chemoimmunotherapy (CIT) and targeted therapy with single-agent ibrutinib are both recommended first-line treatments for chronic lymphocytic leukemia (CLL), although their outcomes have not been directly compared. [...]
2018 - 10.1002/ajh.25259
American Journal of Hematology, Vol. 93 Núm. 11 (november 2018) , p. 1402-1410
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3 p, 208.2 KB |
Silent T-cell receptor cutaneous T-cell lymphoma associated to a clonal plasma cell proliferation
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Caballero, Ana Carolina (Institut d'Investigació Biomèdica Sant Pau) ;
Novelli, Silvana (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Mozos, Ana (Institut d'Investigació Biomèdica Sant Pau) ;
Garcia Muret, Maria Pilar (Institut d'Investigació Biomèdica Sant Pau) ;
Sierra, Jorge (Institut d'Investigació Biomèdica Sant Pau) ;
Briones Meijide, Javier (Institut d'Investigació Biomèdica Sant Pau) ;
Universitat Autònoma de Barcelona
Within T-cell lymphomas (TCL) there are 2 entities expressing gamma-delta TCR: hepatosplenic gamma-delta T-cell lymphoma (HSGDTL) and the primary cutaneous gamma-delta T-cell lymphoma (PCGDTL). PCGDTL is a rare form of Tcell lymphoma with specific tropism for skin that have a dismal prognosis. [...]
2019 - 10.4081/hr.2019.7841
Hematology Reports, Vol. 11 Núm. 1 (19 2019) , p. 6-8
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11 p, 893.9 KB |
SARS-CoV-2 vaccine response and rate of breakthrough infection in patients with hematological disorders
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Piñana, José Luis (Fundación INCLIVA. Instituto de Investigación Sanitaria Hospital Clínico Universitario de Valencia) ;
López-Corral, Lucía (Hospital Clínico Universitario (Salamanca)) ;
Martino Bofarull, Rodrigo (Institut d'Investigació Biomèdica Sant Pau) ;
Vazquez, Lourdes (Hospital Clínico Universitario (Salamanca)) ;
Pérez, Ariadna (Fundación INCLIVA. Instituto de Investigación Sanitaria Hospital Clínico Universitario de Valencia) ;
Martin-Martin, Gabriel Andres (Hospital Clínico Universitario (Salamanca)) ;
Gago, Beatriz (Hospital Regional Universitario Carlos Haya (Málaga)) ;
Sanz-Linares, Gabriela (Institut Català Oncologia-Hospital Duran i Reynals. Institut d'Investigació Biomèdica de Bellvitge) ;
Sánchez Salinas, Andrés (Hospital Clínico Universitario Virgen de la Arrixaca (El Palmar, Múrcia)) ;
Villalon, Lucia B. (Hospital Universitario Fundación Alcorcón) ;
Conesa-García, Venancio (Hospital General Universitario de Elche) ;
Olave, María Teresa (Hospital Clínico Universitario Lozano Blesa. Instituto de Investigacón Sanitaria Aragón) ;
Corona de Lapuerta, Magdalena (Hospital Universitario Ramón y Cajal (Madrid)) ;
Marcos-Corrales, Sara (Hospital Clínico Universitario (Salamanca)) ;
Tormo, Mar (Instituto de Investigación Sanitaria Fundación Para la Investigación del Hospital Clínico de Valencia) ;
Hernandez-Rivas, JA (Hospital Universitario Infanta Leonor) ;
Montoro, Juan B. (Hospital Universitari y politècnic La Fe (València)) ;
Rodríguez-Fernández, Alicia (Hospital Universitario Virgen Macarena (Sevilla, Andalusia)) ;
Risco-Gálvez, Irene (Hospital Arnau de Vilanova (València)) ;
Rodríguez-Belenguer, Pablo (Research Program on Biomedical Informatics (GRIB). Institut Hospital del Mar d'Investigacions Mèdiques. Universitat Pompeu Fabra) ;
Hernandez-Boluda, Juan Carlos (Hospital Clínic Universitari (València)) ;
Garcia Cadenas, Irene (Institut d'Investigació Biomèdica Sant Pau) ;
Ruíz-García, Montserrat M. (Hospital General Universitario de Elche) ;
Muñoz-Bellido, Juan Luis (Hospital Clínico Universitario (Salamanca)) ;
Solano, Carlos (Hospital Clínic Universitari (València)) ;
Cedillo Cedillo, Angel (Hematopoietic Stem Cell Transplantation and Cell Therapy Group) ;
Sureda, Anna (Institut Català Oncologia-Hospital Duran i Reynals. Institut d'Investigació Biomèdica de Bellvitge) ;
Navarro, David (Hospital Clínic Universitari (València))
Background: The clinical efficacy of SARS-CoV-2 vaccines according to antibody response in immunosuppressed patients such as hematological patients has not yet been established. Patients and methods: A prospective multicenter registry-based cohort study conducted from December 2020 to December 2021 by the Spanish transplant and cell therapy group was used to analyze the relationship of antibody response at 3-6 weeks after full vaccination (2 doses) with breakthrough SARS-CoV-2 infection in 1394 patients with hematological disorders. [...]
2022 - 10.1186/s13045-022-01275-7
Journal of hematology & oncology, Vol. 15 Núm. 1 (december 2022) , p. 54
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6 p, 3.4 MB |
Outcome of infection with omicron -2 variant in patients with hematological malignancies : An survey report
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Blennow, Ola (Karolinska University Hospital and Karolinska Institutet (Suècia)) ;
Salmanton-García, Jon (University of Cologne) ;
Nowak, Piotr (Karolinska Institutet (Suecia)) ;
Itri, Federico (San Luigi Gonzaga Hospital - Orbassano) ;
van Doesum, Jaap A (Department of Hematology, University Medical Center Groningen) ;
López-García, Alberto (Fundacion Jimenez Diaz University Hospital) ;
Farina, Francesca (Istituto Scientifico San Raffaele) ;
Jakšić, Ozren (University Hospital Dubrava) ;
Pinczés, László Imre (University of Debrecen) ;
Bilgin, Yavuz M. (ADRZ) ;
Falces-Romero, Iker (Instituto de Salud Carlos III) ;
Jiménez, Moraima (Vall d'Hebron Institut d'Oncologia) ;
Ormazabal-Vélez, Irati (Complejo Hospitalario de Navarra) ;
Weinbergerová, Barbora (University Hospital Brno (República Txeca)) ;
Duléry, Rémy (Sorbonne Université) ;
Stojanoski, Zlate (University of Skopje) ;
Lahmer, Tobias (TU München) ;
Fernández, Noemí (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ;
Hernández-Rivas, José-Ángel (Hospital Universitario Infanta Leonor) ;
Petzer, Verena (Medical University of Innsbruck) ;
De Jonge, Nick (Vrije Universiteit Amsterdam) ;
Glenthøj, Andreas (Copenhagen University Hospital Rigshospitalet) ;
De Ramón-Sánchez, Cristina (Instituto de Investigación Biomédica de Salamanca) ;
Biernat, Monika M. (Wroclaw Medical University) ;
Fracchiolla, Nicola (Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico) ;
Aujayeb, Avinash (Northumbria Healthcare) ;
Van Praet, Jens (AZ Sint-Jan Brugge-Oostende AV) ;
Schönlein, Martin (University Medical Center Hamburg-Eppendorf) ;
Méndez, Gustavo-Adolfo (Hospital Escuela de Agudos Dr. Ramón Madariaga) ;
Cattaneo, Chiara (ASST-Spedali Civili) ;
Guidetti, Anna (Fondazione IRCCS Istituto Nazionale dei Tumori) ;
Sciumè, Mariarita (Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico) ;
Ammatuna, Emanuele (University Medical Center Groningen) ;
Cordoba, Raul (Fundacion Jimenez Diaz University Hospital) ;
García-Poutón, Nicole (Hospital Clínic i Provincial de Barcelona) ;
Gräfe, Stefanie (Universitätsklinikum Hamburg Eppendorf) ;
Cabirta, Alba (Vall d'Hebron Institut d'Oncologia) ;
Wolf, Dominik (Medical University of Innsbruck) ;
Nordlander, Anna (Karolinska University Hospital and Karolinska Institutet (Suècia)) ;
García-Sanz, Ramón (Instituto de Investigación Biomédica de Salamanca) ;
Delia, Mario (AOUC Policlinico) ;
Berg Venemyr, Caroline (Copenhagen University Hospital Rigshospitalet) ;
Brones, Clara (Centre Hospitalier de Versailles) ;
Di Blasi, Roberta (Hopital Saint Louis) ;
De Kort, Elizabeth (Radboud University Medical Center) ;
Meers, Stef (AZ KLINA) ;
Lamure, Sylvain (University Hospital of Montpellier (França)) ;
Serrano, Laura (Hospital Universitario de Cabueñes (Gijón)) ;
Merelli, Maria (ASU FC Udine Hospital) ;
Coppola, Nicola (Universitry of Campania) ;
Bergantim, Rui (Centro Hospitalar e Universitário de São João) ;
Besson, Caroline (Centre Hospitalier de Versailles) ;
Kohn, Milena (Centre Hospitalier de Versailles) ;
Petiti, Jessica (University of Turin) ;
Garcia-Vidal, Carolina (Hospital Clínic i Provincial de Barcelona) ;
Dargenio, Michelina ("Vito Fazzi" Hospital) ;
Danion, François (CHU de Strasbourg) ;
Machado, Marina (Hospital General Universitario Gregorio Marañón) ;
Bailén, Rebeca (Hospital General Universitario Gregorio Marañón) ;
Hoenigl, Martin (Medical University of Graz) ;
Dragonetti, Giulia (Fondazione Policlinico Universitario Agostino Gemelli) ;
Chai, Louis Yi Ann (National University Health System) ;
Kho, Chi Shan (Pamela Youde Nethersole Eastern Hospital) ;
Bonanni, Matteo (Università Cattolica del Sacro Cuore) ;
Liévin, Raphaël (Hopital Saint Louis) ;
Marchesi, Francesco (IRCCS Regina Elena National Cancer Institute) ;
Cornely, Oliver A. (German Centre for Infection Research) ;
Pagano, Livio (Università Cattolica del Sacro Cuore) ;
Universitat Autònoma de Barcelona
2022 - 10.1002/ajh.26626
American Journal of Hematology, Vol. 97 (june 2022) , p. E312-E317
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