UAB Digital Repository of Documents 38 records found  1 - 10nextend  jump to record: Search took 0.02 seconds. 
1.
16 p, 641.2 KB Machine learning to understand the immune-inflammatory pathways in fibromyalgia / Andrés-Rodríguez, Laura (Universitat Autònoma de Barcelona) ; Borràs i Hernández, Francesc Xavier (Universitat Autònoma de Barcelona) ; Feliu Soler, Albert (Universitat Autònoma de Barcelona) ; Pérez-Aranda, Adrián (Parc Sanitari Sant Joan de Déu) ; Rozadilla-Sacanell, Antoni (Parc Sanitari Sant Joan de Déu) ; Arranz, Belén (Parc Sanitari Sant Joan de Déu) ; Montero-Marín, Jesús (RedIAPP (Red de Investigación en Actividades Preventivas y Promoción de la Salud)) ; García-Campayo, Javier (RedIAPP (Red de Investigación en Actividades Preventivas y Promoción de la Salud)) ; Angarita Osorio, Natalia (Parc Sanitari Sant Joan de Déu) ; Maes, Michael (Chulalongkorn University) ; Luciano, Juan V. (Parc Sanitari Sant Joan de Déu)
Fibromyalgia (FM) is a chronic syndrome characterized by widespread musculoskeletal pain, and physical and emotional symptoms. Although its pathophysiology is largely unknown, immune-inflammatory pathways may be involved. [...]
2019 - 10.3390/ijms20174231
International Journal of Molecular Sciences, Vol. 20, núm. 17 (2019) , p. 4231  
2.
12 p, 2.5 MB Lgr5 Does Not Vary Throughout the Menstrual Cycle in Endometriotic Human Eutopic Endometrium / Vallvé Juanico, Júlia (Hospital Universitari Vall d'Hebron) ; Barón, Cristian (Hospital Universitari Vall d'Hebron) ; Suárez Salvador, Elena (Hospital Universitari Vall d'Hebron) ; Castellví Vives, Josep (Hospital Universitari Vall d'Hebron) ; Ballesteros, Agustín (Hospital Universitari Vall d'Hebron) ; Gil Moreno, Antonio (Universitat Autònoma de Barcelona) ; Santamaria, Xavier (Igenomix Foundation)
Endometriosis is characterized by the abnormal presence of endometrium outside of the uterus, resulting in pelvic pain and infertility. The leucine-rich repeat-containing G protein-coupled receptor 5 (LGR5) has been postulated to be a marker of stem cells in the endometrium. [...]
2019 - 10.3390/ijms20010022
International Journal of Molecular Sciences, Vol. 20, Núm. 1 (January 2019) , art. 22  
3.
10 p, 1.7 MB Omalizumab is equally effective in persistent allergic oral corticosteroid-dependent asthma caused by either seasonal or perennial allergens : A pilot study / Domingo, Christian (Universitat Autònoma de Barcelona. Department de Medicina) ; Pomares, Xavier (CIBER de Enfermedades Respiratorias. CIBERES) ; Navarro, Albert (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i de Medicina Preventiva i Salut Pública) ; Rudi, Núria (Corporació Sanitària Parc Taulí) ; Sogo, Ana (Universitat Autònoma de Barcelona. Department de Medicina) ; Dávila, Ignacio (Hospital Universitari de Salamanca.) ; Mirapeix, Rosa M. (Universitat Autònoma de Barcelona. Departament de Ciències Morfològiques)
Omalizumab is marketed for chronic severe asthma patients who are allergic to perennial allergens. Our purpose was to investigate whether omalizumab is also effective in persistent severe asthma due to seasonal allergens. [...]
2017 - 10.3390/ijms18030521
International Journal of Molecular Sciences, Vol. 18 Núm. 3 (28 2017) , p. 521  
4.
15 p, 2.3 MB Biomphalaria glabrata metallothionein : Lacking metal specificity of the protein and missing gene upregulation suggest metal sequestration by exchange instead of through selective binding / Niederwanger, Michael (University of Innsbruck. Institute of Zoology and Center of Molecular Biosciences Innsbruck) ; Calatayud, Sara (Universitat de Barcelona. Departament de Biologia evolutiva. Institut de Recerca de la Biodiversitat) ; Zerbe, Oliver (University of Zürich. Department of Chemistry) ; Atrian, Silvia (Universitat de Barcelona. Departament de Biologia evolutiva. Institut de Recerca de la Biodiversitat) ; Albalat, Ricard (Universitat de Barcelona. Departament de Biologia evolutiva. Institut de Recerca de la Biodiversitat) ; Capdevila Vidal, Mercè (Universitat Autònoma de Barcelona. Departament de Química) ; Palacios Bonilla, Òscar (Universitat Autònoma de Barcelona. Departament de Química) ; Dallinger, Reinherd (University of Innsbruck. Institute of Zoology and Center of Molecular Biosciences Innsbruck)
The wild-type metallothionein (MT) of the freshwater snail Biomphalaria glabrata and a natural allelic mutant of it in which a lysine residue was replaced by an asparagine residue, were recombinantly expressed and analyzed for their metal-binding features with respect to Cd, Zn and Cu, applying spectroscopic and mass-spectrometric methods. [...]
2017 - 10.3390/ijms18071457
International Journal of Molecular Sciences, Vol. 18, Num. 7 (July 2017) , art. 1457  
5.
16 p, 2.8 MB Replacing nitrogen by sulfur : From structurally disordered eumelanins to regioregular thiomelanin polymers / Iacomino, Mariagrazia (University of Naples "Federico II". Department of Chemical Sciences) ; Mancebo Aracil, Juan (Institut Català de Nanociència i Nanotecnologia) ; Guardingo Melián, Mireia (Universitat Autònoma de Barcelona. Department de Química) ; Martín, Raquel (Universitat Autònoma de Barcelona. Department de Química) ; D'Errico, Gerardino (University of Naples "Federico II". Department of Chemical Sciences) ; Perfetti, Marco (University of Naples "Federico II". Department of Chemical Sciences) ; Manini, Paola (University of Naples "Federico II". Department of Chemical Sciences) ; Crescenzi, Orlando (University of Naples "Federico II". Department of Chemical Sciences) ; Busqué Sánchez, Félix (Universitat Autònoma de Barcelona. Departament de Química) ; Napolitano, Alessandra (University of Naples "Federico II". Department of Chemical Sciences) ; d'Ischia, Marco (University of Naples "Federico II". Department of Chemical Sciences) ; Sedó, Josep (Institut Català de Nanociència i Nanotecnologia) ; Ruiz Molina, Daniel (Institut Català de Nanociència i Nanotecnologia)
The oxidative polymerization of 5,6-dihydroxybenzothiophene (DHBT), the sulfur analog of the key eumelanin building block 5,6-dihydroxyindole (DHI), was investigated to probe the role of nitrogen in eumelanin build-up and properties. [...]
2017 - 10.3390/ijms18102169
International Journal of Molecular Sciences, Vol. 18, Núm. 10 (October 2017) , art. 2169  
6.
13 p, 2.6 MB The inhibitory effects of cobalt protoporphyrin IX and cannabinoid 2 receptor agonists in type 2 diabetic mice / McDonnell, Christina (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Leánez, Sergi (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Pol, Olga (Institut d'Investigació Biomèdica Sant Pau)
The activation of the transcription factor Nrf2 inhibits neuropathy and modulates the activity of delta-opioid receptors (DOR) in type 2 diabetic mice but the impact of Nrf2/HO-1 pathway on the antinociceptive actions of cannabinoid 2 receptors (CB2R) has not been assessed. [...]
2017 - 10.3390/ijms18112268
International Journal of Molecular Sciences, Vol. 18 Núm. 11 (november 2017) , p. 2268  
7.
19 p, 3.2 MB Biochemical and MALDI-TOF mass spectrometric characterization of a novel native and recombinant cystine knot miniprotein from Solanum tuberosum subsp. andigenum cv. Churqueña / Cotabarren, Juliana (Universidad Nacional de La Plata. Centro de Investigación de Proteínas Vegetales (CIPROVE). Departamento de Ciencias Biológicas) ; Tellechea, Mariana Edith (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Tanco, Sebastián Martín (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Lorenzo Rivera, Julia (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Garcia Pardo, Javier (Institut Català de Nanociència i Nanotecnologia) ; Avilés, Francesc X. (Francesc Xavier) (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Obregón, Walter David (Universidad Nacional de La Plata. Centro de Investigación de Proteínas Vegetales (CIPROVE). Departamento de Ciencias Biológicas)
Cystine-knot miniproteins (CKMPs) are an intriguing group of cysteine-rich molecules that combine the characteristics of proteins and peptides. Typically, CKMPs are fewer than 50 residues in length and share a characteristic knotted scaffold characterized by the presence of three intramolecular disulfide bonds that form the singular knotted structure. [...]
2018 - 10.3390/ijms19030678
International Journal of Molecular Sciences, Vol. 19, Núm. 3 (February 2018) , art. 678  
8.
21 p, 2.3 MB Generation of immortalised but unstable cells after hTERT introduction in telomere-compromised and p53-deficient vHMECS / Bernal, Aina (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Zafon, Elisenda (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Domínguez, Daniel (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Bertran, Enric (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Tusell Padrós, Laura (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
Telomeres, the natural ends of chromosomes, hide the linear telomeric DNA from constitutive exposure to the DNA damage response with a lariat structure or t-loop. Progressive telomere shortening associated with DNA replication in the absence of a compensatory mechanism culminates in t-loop collapse and unmasked telomeres. [...]
2018 - 10.3390/ijms19072078
International Journal of Molecular Sciences, Vol. 19 Núm. 7 (17 2018) , p. 2078  
9.
17 p, 3.4 MB Protein environment : A crucial triggering factor in josephin domain aggregation: The role of 2,2,2-trifluoroethanol / Visentin, Cristina (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Navarro, Susanna (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Grasso, Gianvito (Università della Svizzera italiana. Istituto Dalle Molle di Studi sull'Intelligenza Artificiale (IDSIA)) ; Regonesi, Maria Elena (Università di Milano-Bicocca. Dipartimento di Biotecnologie e Bioscienze) ; Deriu, Marco Agostino (Università della Svizzera italiana. Istituto Dalle Molle di Studi sull'Intelligenza Artificiale (IDSIA)) ; Tortora, Paolo (Università di Milano-Bicocca. Dipartimento di Biotecnologie e Bioscienze) ; Ventura, Salvador (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular)
The protein ataxin-3 contains a polyglutamine stretch that triggers amyloid aggregation when it is expanded beyond a critical threshold. This results in the onset of the spinocerebellar ataxia type 3. [...]
2018 - 10.3390/ijms19082151
International Journal of Molecular Sciences, Vol. 19, Núm. 8 (August 2018) , art. 2151  
10.
15 p, 4.2 MB Effects of liposomal formulation of citicoline in experimental diabetes-induced retinal neurodegeneration / Bogdanov, Patricia (CIBERDEM (Instituto de Salud Carlos III)) ; Sampedro, Joel (CIBERDEM (Instituto de Salud Carlos III)) ; Solà-Adell, Cristina (CIBERDEM (Instituto de Salud Carlos III)) ; Simó-Servat, Olga (Universitat Autònoma de Barcelona. Departament de Medicina) ; Russo, Carla (R&D Department. Omikron Italia Srl) ; Varela-Sende, Luisa (Clinical Research Department. OPKO Health Spain S.L) ; Simó, Rafael (Universitat Autònoma de Barcelona. Departament de Medicina) ; Hernández Pascual, Cristina (Universitat Autònoma de Barcelona. Departament de Medicina)
Diabetic retinopathy (DR) has been classically considered a microcirculatory disease of the retina. However, there is growing evidence to suggest that retinal neurodegeneration is also an early event in the pathogenesis of DR. [...]
2018 - 10.3390/ijms19082458
International Journal of Molecular Sciences, Vol. 19 Núm. 8 (20 2018) , p. 2458  

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