Depósito Digital de Documentos de la UAB Encontrados 49 registros  1 - 10siguientefinal  ir al registro: La búsqueda tardó 0.02 segundos. 
1.
16 p, 4.3 MB Ischemic postconditioning reduces reperfusion arrhythmias by adenosine receptors and protein kinase C activation but is independent of KATP channels or connexin 43 / Diez, E.R. (Institute of Medical and Experimental Biology of Cuyo. CONICET) ; Sánchez, J.A. (Universitat Autònoma de Barcelona. Departament de Medicina) ; Prado, N.J. (Institute of Medical and Experimental Biology of Cuyo. CONICET) ; Zumino, A.Z.P. (Institute of Medical and Experimental Biology of Cuyo. CONICET) ; García-Dorado, D. (Universitat Autònoma de Barcelona. Departament de Medicina) ; Miatello, R.M. (Institute of Medical and Experimental Biology of Cuyo. CONICET) ; Rodríguez-Sinovas, A. (Centro de Investigación Biomédica en Red sobre Enfermedades Cardiovasculares (CIBERCV))
Ischemic postconditioning (IPoC) reduces reperfusion arrhythmias but the antiarrhythmic mechanisms remain unknown. The aim of this study was to analyze IPoC electrophysiological effects and the role played by adenosine A, A and A receptors, protein kinase C, ATP-dependent potassium (K) channels, and connexin 43. [...]
2019 - 10.3390/ijms20235927
International journal of molecular sciences, Vol. 20 Núm. 23 (january 2019) , p. 5927  
2.
13 p, 1.8 MB Extracellular albumin covalently sequesters selenocompounds and determines cytotoxicity / Zheng, Wenyi (Karolinska Institute Stockholm. Department of Laboratory Medicine) ; Boada, Roberto (Universitat Autònoma Barcelona. Departament de Química) ; He, Riu (Karolinska Institute Stockholm. Department of Laboratory Medicine) ; Xiao, Tingting (Universitat Autònoma Barcelona. Departament de Química) ; Ye, Fei (Kungliga Tekniska högskolan. Division of Functional Nanomaterials) ; Simonelli, Laura (ALBA Laboratori de Llum de Sincrotró) ; Valiente Malmagro, Manuel (Universitat Autònoma de Barcelona. Departament de Química) ; Zhao, Ying (Karolinska Institute Stockholm. Department of Laboratory Medicine) ; Hassan, Moustapha (Karolinska Institute Stockholm. Department of Laboratory Medicine)
Selenocompounds (SeCs) are well-known nutrients and promising candidates for cancer therapy; however, treatment efficacy is very heterogeneous and the mechanism of action is not fully understood. Several SeCs have been reported to have albumin-binding ability, which is an important factor in determining the treatment efficacy of drugs. [...]
2019 - 10.3390/ijms20194734
International journal of molecular sciences, Vol. 20, issue 19 (Oct. 2019) , art. 4734  
3.
25 p, 1.3 MB How plants handle trivalent (+3) elements / Poschenrieder, Charlotte (Universitat Autònoma de Barcelona. Laboratori de Fisiologia Vegetal) ; Busoms González, Sílvia (University of Nottingham. Plant Sciences, Future Food Beacon of Excellence) ; Barceló Coll, Juan (Universitat Autònoma de Barcelona. Laboratori de Fisiologia Vegetal)
Plant development and fitness largely depend on the adequate availability of mineral elements in the soil. Most essential nutrients are available and can be membrane transported either as mono or divalent cations or as mono-or divalent anions. [...]
2019 - 10.3390/ijms20163984
International journal of molecular sciences, Vol. 20, Issue 16 (August 2019) , art. 3984  
4.
18 p, 3.9 MB Gpathfinder : Identification of ligand-binding pathways by a multi-objective genetic algorithm / Sánchez Aparicio, José Emilio (Universitat Autònoma de Barcelona. Departament de Química Universitat Autònoma de Barcelona) ; Sciortino, Giuseppe (Universitat Autònoma de Barcelona. Departament de Química) ; Viladrich Herrmannsdoerfer, Daniel (Universitat Autònoma de Barcelona. Departament de Química) ; Orenes Chueca, Pablo (Universitat Autònoma de Barcelona. Departament de Química) ; Rodríguez-Guerra Pedregal, Jaime (Universitat Autònoma de Barcelona. Departament de Química) ; Maréchal, Jean-Didier (Universitat Autònoma de Barcelona. Departament de Química)
Protein-ligand docking is a widely used method to generate solutions for the binding of a small molecule with its target in a short amount of time. However, these methods provide identification of physically sound protein-ligand complexes without a complete view of the binding process dynamics, which has been recognized to be a major discriminant in binding affinity and ligand selectivity. [...]
2019 - 10.3390/ijms20133155
International journal of molecular sciences, Vol. 20, Issue 13 (July 2019) , art. 3155  
5.
25 p, 3.0 MB Distinct dopamine D2 receptor antagonists differentially impact D2 receptor oligomerization / Wouters, Elise (Laboratory of Toxicology. Department of Bioanalysis. Faculty of Pharmaceutical Sciences. Ghent University) ; Ricarte Marín, Adrián (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Dalton, James Andrew Rupert (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Giraldo, Jesús (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Stove, Christophe. (Laboratory of Toxicology. Department of Bioanalysis. Faculty of Pharmaceutical Sciences. Ghent University)
Dopamine D receptors (DR) are known to form transient homodimer complexes, of which the increased formation has already been associated with development of schizophrenia. Pharmacological targeting and modulation of the equilibrium of these receptor homodimers might lead to a better understanding of the critical role played by these complexes in physiological and pathological conditions. [...]
2019 - 10.3390/ijms20071686
International Journal of Molecular Sciences, Vol. 20 Núm. 7 (january 2019) , p. 1686  
6.
11 p, 2.2 MB The membrane proximal domain of TRPV1 and TRPV2 channels mediates protein-protein interactions and lipid binding in vitro / Doñate Macián, Pau (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Álvarez Marimon, Elena (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Sepulcre, Francesc (Universitat Politècnica de Catalunya. Departament d'Enginyeria Agroalimentària i Biotecnologia) ; Vázquez Ibar, José Luis (Institut des Sciences du Vivant Frédéric-JOLIOT. CEA-Saclay) ; Perálvarez Marín, Alex (Institut de Neurociències)
Constitutive or regulated membrane protein trafficking is a key cell biology process. Transient receptor potential channels are somatosensory proteins in charge of detecting several physical and chemical stimuli, thus requiring fine vesicular trafficking. [...]
2019 - 10.3390/ijms20030682
International journal of molecular sciences, Vol. 20, Issue 3 (February 2019) , art. 682  
7.
14 p, 1.9 MB The effects of cobalt protoporphyrin IX and tricarbonyldichlororuthenium (II) dimer treatments and its interaction with nitric oxide in the locus coeruleus of mice with peripheral inflammation / Moreno, P. (Institut d'Investigació Biomèdica Sant Pau) ; Cazuza, R.A. (Department of Psychology. University of São Paulo) ; Gomes-Mendes, J. (Department of Psychology. University of São Paulo) ; Díaz, A.F. (Institut de Neurociències. Universitat Autònoma de Barcelona) ; Polo, S. (Institut de Neurociències. Universitat Autònoma de Barcelona) ; Leánez, S. (Institut de Neurociències. Universitat Autònoma de Barcelona) ; Leite-Panissi, C.R.A. (Department of Psychology. University of São Paulo) ; Pol, Olga. (Institut de Neurociències. Universitat Autònoma de Barcelona)
Heme oxygenase 1 (HO-1) and carbon monoxide were shown to normalize oxidative stress and inflammatory reactions induced by neuropathic pain in the central nervous system, but their effects in the locus coeruleus (LC) of animals with peripheral inflammation and their interaction with nitric oxide are unknown. [...]
2019 - 10.3390/ijms20092211
International journal of molecular sciences, Vol. 20, Issue 9 (January 2019) , p. 2211  
8.
24 p, 3.0 MB Insight into the Antifungal Mechanism of Action of Human RNase N-terminus Derived Peptides / Salazar Montoya, Vivian Angélica (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular.) ; Arranz Trullén, Javier (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Prats Ejarque, Guillem (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Torrent Burgas, Marc (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Andreu, D. (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ; Pulido Gomez, David (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Boix i Borràs, Esther (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
Candida albicans is a polymorphic fungus responsible for mucosal and skin infections. Candida cells establish themselves into biofilm communities resistant to most currently available antifungal agents. [...]
2019 - 10.3390/ijms20184558
International journal of molecular sciences, Vol. 20, Issue 18 (September 2019) , art.4558  
9.
13 p, 1.1 MB Cyclobutane-Containing Scaffolds as Useful Intermediates in the Stereoselective Synthesis of Suitable Candidates for Biomedical Purposes : Surfactants, Gelators and Metal Cation Ligands / Illa Soler, Ona (Universitat Autònoma de Barcelona. Departament de Química) ; Serra, Albert (Universitat Autònoma de Barcelona. Departament de Química) ; Ardiaca, Agustí (Universitat Autònoma de Barcelona. Departament de Química) ; Herrero, Xavier (Universitat Autònoma de Barcelona. Departament de Química) ; Closa, Guillem (Universitat Autònoma de Barcelona. Departament de Química) ; Ortuño Mingarro, Rosa María (Universitat Autònoma de Barcelona. Departament de Química)
Efficient and versatile synthetic methodologies are reported for the preparation of products that are suitable candidates to be used as surfactants, gelators for hydroxylic solvents or metal cation ligands, with potential use in several fields including biomedical applications. [...]
2019 - 10.3390/ijms20184333
International journal of molecular sciences, Vol. 20, Issue 18 (September 2019) , art. 4333  
10.
20 p, 6.5 MB SOCS1-derived peptide administered by eye drops prevents retinal neuroinflammation and vascular leakage in experimental diabetes / Hernández, C. (Universitat Autònoma de Barcelona. Departament de Medicina) ; Bogdanov, P. (Institut de Recerca Vall d'Hebron) ; Gómez Guerrero, C. (Renal, Vascular and Diabetes Research Lab. Instituto de Investigacion Sanitaria-Fundación Jimenez Diaz.) ; Sampedro, J. (Institut de Recerca Vall d'Hebron) ; Solà-Adell, C. (Institut de Recerca Vall d'Hebron) ; Espejo, C. (Institut de Recerca Vall d'Hebron) ; García-Ramírez, M. (Institut de Recerca Vall d'Hebron) ; Prieto, I. (Renal, Vascular and Diabetes Research Lab. Instituto de Investigacion Sanitaria-Fundación Jimenez Diaz.) ; Egido, J. (Renal, Vascular and Diabetes Research Lab. Instituto de Investigacion Sanitaria-Fundación Jimenez Diaz) ; Simó, R. (Universitat Autònoma de Barcelona. Departament de Medicina)
Current treatments for diabetic retinopathy (DR) target late stages when vision has already been significantly affected. Accumulating evidence suggests that neuroinflammation plays a major role in the pathogenesis of DR, resulting in the disruption of the blood-retinal barrier. [...]
2019 - 10.3390/ijms20153615
International journal of molecular sciences, Vol. 20 Núm. 15 (january 2019) , p. 3615  

Depósito Digital de Documentos de la UAB : Encontrados 49 registros   1 - 10siguientefinal  ir al registro:
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