Depósito Digital de Documentos de la UAB Encontrados 32 registros  1 - 10siguientefinal  ir al registro: La búsqueda tardó 0.01 segundos. 
1.
15 p, 2.3 MB Biomphalaria glabrata metallothionein : Lacking metal specificity of the protein and missing gene upregulation suggest metal sequestration by exchange instead of through selective binding / Niederwanger, Michael (University of Innsbruck. Institute of Zoology and Center of Molecular Biosciences Innsbruck) ; Calatayud, Sara (Universitat de Barcelona. Departament de Biologia evolutiva. Institut de Recerca de la Biodiversitat) ; Zerbe, Oliver (University of Zürich. Department of Chemistry) ; Atrian, Silvia (Universitat de Barcelona. Departament de Biologia evolutiva. Institut de Recerca de la Biodiversitat) ; Albalat, Ricard (Universitat de Barcelona. Departament de Biologia evolutiva. Institut de Recerca de la Biodiversitat) ; Capdevila Vidal, Mercè (Universitat Autònoma de Barcelona. Departament de Química) ; Palacios Bonilla, Òscar (Universitat Autònoma de Barcelona. Departament de Química) ; Dallinger, Reinherd (University of Innsbruck. Institute of Zoology and Center of Molecular Biosciences Innsbruck)
The wild-type metallothionein (MT) of the freshwater snail Biomphalaria glabrata and a natural allelic mutant of it in which a lysine residue was replaced by an asparagine residue, were recombinantly expressed and analyzed for their metal-binding features with respect to Cd, Zn and Cu, applying spectroscopic and mass-spectrometric methods. [...]
2017 - 10.3390/ijms18071457
International Journal of Molecular Sciences, Vol. 18, Num. 7 (July 2017) , art. 1457  
2.
16 p, 2.8 MB Replacing nitrogen by sulfur : From structurally disordered eumelanins to regioregular thiomelanin polymers / Iacomino, Mariagrazia (University of Naples “Federico II”. Department of Chemical Sciences) ; Mancebo Aracil, Juan (Institut Català de Nanociència i Nanotecnologia) ; Guardingo Melián, Mireia (Universitat Autònoma de Barcelona. Department de Química) ; Martín, Raquel (Universitat Autònoma de Barcelona. Department de Química) ; D'Errico, Gerardino (University of Naples “Federico II”. Department of Chemical Sciences) ; Perfetti, Marco (University of Naples “Federico II”. Department of Chemical Sciences) ; Manini, Paola (University of Naples “Federico II”. Department of Chemical Sciences) ; Crescenzi, Orlando (University of Naples “Federico II”. Department of Chemical Sciences) ; Busqué Sánchez, Félix (Universitat Autònoma de Barcelona. Departament de Química) ; Napolitano, Alessandra (University of Naples “Federico II”. Department of Chemical Sciences) ; d'Ischia, Marco (University of Naples “Federico II”. Department of Chemical Sciences) ; Sedó, Josep (Institut Català de Nanociència i Nanotecnologia) ; Ruiz Molina, Daniel (Institut Català de Nanociència i Nanotecnologia)
The oxidative polymerization of 5,6-dihydroxybenzothiophene (DHBT), the sulfur analog of the key eumelanin building block 5,6-dihydroxyindole (DHI), was investigated to probe the role of nitrogen in eumelanin build-up and properties. [...]
2017 - 10.3390/ijms18102169
International Journal of Molecular Sciences, Vol. 18, Núm. 10 (October 2017) , art. 2169  
3.
19 p, 3.2 MB Biochemical and MALDI-TOF mass spectrometric characterization of a novel native and recombinant cystine knot miniprotein from Solanum tuberosum subsp. andigenum cv. Churqueña / Cotabarren, Juliana (Universidad Nacional de La Plata. Centro de Investigación de Proteínas Vegetales (CIPROVE). Departamento de Ciencias Biológicas) ; Tellechea, Mariana Edith (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Tanco, Sebastián Martín (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Lorenzo Rivera, Julia (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Garcia Pardo, Javier (Institut Català de Nanociència i Nanotecnologia) ; Avilés, Francesc X. (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Obregón, Walter David (Universidad Nacional de La Plata. Centro de Investigación de Proteínas Vegetales (CIPROVE). Departamento de Ciencias Biológicas)
Cystine-knot miniproteins (CKMPs) are an intriguing group of cysteine-rich molecules that combine the characteristics of proteins and peptides. Typically, CKMPs are fewer than 50 residues in length and share a characteristic knotted scaffold characterized by the presence of three intramolecular disulfide bonds that form the singular knotted structure. [...]
2018 - 10.3390/ijms19030678
International Journal of Molecular Sciences, Vol. 19, Núm. 3 (February 2018) , art. 678  
4.
17 p, 3.4 MB Protein environment : A crucial triggering factor in josephin domain aggregation: The role of 2,2,2-trifluoroethanol / Visentin, Cristina (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Navarro, Susanna (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Grasso, Gianvito (Università della Svizzera italiana. Istituto Dalle Molle di Studi sull'Intelligenza Artificiale (IDSIA)) ; Regonesi, Maria Elena (Università di Milano-Bicocca. Dipartimento di Biotecnologie e Bioscienze) ; Deriu, Marco Agostino (Università della Svizzera italiana. Istituto Dalle Molle di Studi sull'Intelligenza Artificiale (IDSIA)) ; Tortora, Paolo (Università di Milano-Bicocca. Dipartimento di Biotecnologie e Bioscienze) ; Ventura i Zamora, Salvador (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular)
The protein ataxin-3 contains a polyglutamine stretch that triggers amyloid aggregation when it is expanded beyond a critical threshold. This results in the onset of the spinocerebellar ataxia type 3. [...]
2018 - 10.3390/ijms19082151
International Journal of Molecular Sciences, Vol. 19, Núm. 8 (August 2018) , art. 2151  
5.
15 p, 4.2 MB Effects of liposomal formulation of citicoline in experimental diabetes-induced retinal neurodegeneration / Bogdanov, Patricia (CIBERDEM (Instituto de Salud Carlos III)) ; Sampedro, Joel (CIBERDEM (Instituto de Salud Carlos III)) ; Solà-Adell, Cristina (CIBERDEM (Instituto de Salud Carlos III)) ; Simó-Servat, Olga (Universitat Autònoma de Barcelona. Departament de Medicina) ; Russo, Carla (R&D Department. Omikron Italia Srl) ; Varela-Sende, Luisa (Clinical Research Department. OPKO Health Spain S.L) ; Simó, Rafael (Universitat Autònoma de Barcelona. Departament de Medicina) ; Hernández, Cristina (Universitat Autònoma de Barcelona. Departament de Medicina)
Diabetic retinopathy (DR) has been classically considered a microcirculatory disease of the retina. However, there is growing evidence to suggest that retinal neurodegeneration is also an early event in the pathogenesis of DR. [...]
2018 - 10.3390/ijms19082458
International Journal of Molecular Sciences, Vol. 19 Núm. 8 (20 2018) , p. 2458  
6.
17 p, 3.8 MB Two different strategies to enhance osseointegration in porous titanium : Inorganic thermo-chemical treatment versus organic coating by peptide adsorption / Ortiz-Hernandez, Monica (Universitat Politècnica de Catalunya. Barcelona Research Center in Multiscale Science and Engineering) ; Rappe, Katrin Steffanie (Universitat Autònoma de Barcelona. Departament de Cirugia Animal) ; Molmeneu, Meritxell (Universitat Politècnica de Catalunya. Barcelona Research Center in Multiscale Science and Engineering) ; Mas-Moruno, Carles (Universitat Politècnica de Catalunya. Barcelona Research Center in Multiscale Science and Engineering) ; Guillem-Marti, Jordi (Universitat Politècnica de Catalunya. Barcelona Research Center in Multiscale Science and Engineering) ; Punset, Miquel (Universitat Politècnica de Catalunya. Barcelona Research Center in Multiscale Science and Engineering) ; Caparros, Cristina (Universitat Politècnica de Catalunya. Barcelona Research Center in Multiscale Science and Engineering) ; Calero, Jose (Universitat Politècnica de Catalunya. Biomaterials Biomechanics and Tissue Engineering Group (BBT). Department of Materials Science and Metallurgical Engineering) ; Franch Serracanta, Jordi (Universitat Autònoma de Barcelona. Departament de Cirugia Animal) ; Fernandez-Fairen, Mariano (Universidad Internacional de Cataluña. Facultad de Odontología. Campus de Medicina y Ciencias de la Salud) ; Gil, Javier (Universidad Internacional de Cataluña. Facultad de Odontología. Campus de Medicina y Ciencias de la Salud)
In this study, highly-interconnected porous titanium implants were produced by powder sintering with different porous diameters and open interconnectivity. The actual foams were produced using high cost technologies: Chemical Vapor Deposition (CVD), Physical Vapor Deposition (PVD), and spark plasma sintering, and the porosity and/or interconnection was not optimized. [...]
2018 - 10.3390/ijms19092574
International Journal of Molecular Sciences, Vol. 19 Núm. 9 (september 2018) , p. 2574  
7.
18 p, 288.5 KB Translational research opportunities regarding homologous recombination in ovarian cancer / Romeo Marín, Margarita (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Pardo, J.C. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Martínez Cardús, Anna (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Martínez Balibrea, Eva (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Quiroga, Vanesa (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Martínez Román, Sergio (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Solé, Francesc (Institut Germants Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Margelí, Mireia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Mesía, Ricard (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Universitat Autònoma de Barcelona
Homologous recombination (HR) is a DNA repair pathway that is deficient in 50% of high-grade serous ovarian carcinomas (HGSOC). Deficient HR (DHR) constitutes a therapeutic opportunity for these patients, thanks to poly (ADP-ribose) polymerases (PARP) inhibitors (PARPi; olaparib, niraparib, and rucaparib are already commercialized). [...]
2018 - 10.3390/ijms19103249
International Journal of Molecular Sciences, Vol. 19 Núm. 10 (19 2018) , p. 3249  
8.
16 p, 3.1 MB Neuroprotective effects of the multitarget agent AVCRI104P3 in brain of middle-aged mice / Relat, J. (Department of Pharmacology. Therapeutic and Toxicology. Autonomous University of Barcelona) ; Come, J. (Department of Pharmacology. Therapeutic and Toxicology. Autonomous University of Barcelona) ; Perez, B. (Department of Pharmacology. Therapeutic and Toxicology. Autonomous University of Barcelona) ; Camps, P. (Laboratory of Pharmaceutical Chemistry (CSIC Associated Unit). Faculty of Pharmacy and Food Sciences. Institute of Biomedicine (IBUB). University of Barcelona) ; Muñoz-Torrero, D. (Laboratory of Pharmaceutical Chemistry (CSIC Associated Unit). Faculty of Pharmacy and Food Sciences. Institute of Biomedicine (IBUB). University of Barcelona) ; Badia, A. (Department of Pharmacology. Therapeutic and Toxicology. Autonomous University of Barcelona) ; Gimenez-Llort, L. (Department of Psychiatry and Forensic Medicine. Autonomous University of Barcelona) ; Clos, M.V. (Department of Pharmacology. Therapeutic and Toxicology. Autonomous University of Barcelona)
Molecular factors involved in neuroprotection are key in the design of novel multitarget drugs in aging and neurodegeneration. AVCRI104P3 is a huprine derivative that exhibits potent inhibitory effects on human AChE, BuChE, and BACE-1 activities, as well as on AChE-induced and self-induced Aβ aggregation. [...]
2018 - 10.3390/ijms19092615
International Journal of Molecular Sciences, Vol. 19 Núm. 9 (april 2018) , p. 2615  
9.
19 p, 5.0 MB We Are What We Eat : A Stoichiometric and Ecometabolomic Study of Caterpillars Feeding on Two Pine Subspecies of Pinus sylvestris / Rivas-Ubach, Albert (Centre de Recerca Ecològica i Aplicacions Forestals) ; Peñuelas, Josep (Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia) ; Hódar, José Antonio (Universidad de Granada. Departamento de Biología Animal y Ecología) ; Oravec, Michal (Czech Academy of Sciences. Global Change Research Institute) ; Paša-Tolić, Ljiljana (Pacific Northwest National Laboratory. Environmental Molecular Sciences Laboratory) ; Urban, Otmar (Czech Academy of Sciences. Global Change Research Institute) ; Sardans i Galobart, Jordi (Centre de Recerca Ecològica i Aplicacions Forestals)
Many studies have addressed several plant-insect interaction topics at nutritional, molecular, physiological, and evolutionary levels. However, it is still unknown how flexible the metabolism and the nutritional content of specialist insect herbivores feeding on different closely related plants can be. [...]
2019 - 10.3390/ijms20010059
International Journal of Molecular Sciences, Vol. 20, Núm. 1 (January 2019) , art. 59  
10.
21 p, 2.5 MB Unveiling the multifaceted mechanisms of antibacterial activity of buforin II and frenatin 2.3S peptides from skin micro-organs of the orinoco lime treefrog (Sphaenorhynchus lacteus) / Muñoz-Camargo, Carolina (Universidad de los Andes) ; Salazar, Vivian A. (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Barrero-Guevara, Laura (Universidad de los Andes) ; Camargo, Sandra (Universidad de los Andes) ; Mosquera, Ángela (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Groot, Helena (Universidad de los Andes) ; Boix i Borràs, Esther (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular)
Amphibian skin is a rich source of natural compounds with diverse antimicrobial and immune defense properties. Our previous studies showed that the frog skin secretions obtained by skin micro-organs from various species of Colombian anurans have antimicrobial activities against bacteria and viruses. [...]
2018 - 10.3390/ijms19082170
International journal of molecular sciences, Vol. 19, issue 8 (August 2018) , art. 2170  

Depósito Digital de Documentos de la UAB : Encontrados 32 registros   1 - 10siguientefinal  ir al registro:
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