UAB Digital Repository of Documents 3 records found  Search took 0.01 seconds. 
1.
14 p, 2.2 MB Charge effect of a liposomal delivery system encapsulating simvastatin to treat experimental ischemic stroke in rats / Campos Martorell, Mireia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Cano-Sarabia, Mary (Institut Català de Nanociència i Nanotecnologia) ; Simats, Alba (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Hernández Guillamón, María del Mar (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Rosell, Anna (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Maspoch Comamala, Daniel (Institut Català de Nanociència i Nanotecnologia) ; Montaner, Joan (Hospital Universitari Vall d'Hebron) ; Universitat Autònoma de Barcelona
Although the beneficial effects of statins on stroke have been widely demonstrated both in experimental studies and in clinical trials, the aim of this study is to prepare and characterize a new liposomal delivery system that encapsulates simvastatin to improve its delivery into the brain. [...]
2016 - 10.2147/IJN.S107292
International Journal of Nanomedicine, Vol. 11 (June 2016) , p. 3035-3048  
2.
12 p, 2.4 MB Enhancing microparticle internalization by nonphagocytic cells through the use of noncovalently conjugated polyethyleneimine / Patiño, Tania (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Nogués, C (Carme) (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Ibáñez, Elena (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Barrios, Leonardo (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
Development of micro- and nanotechnology for the study of living cells, especially in the field of drug delivery, has gained interest in recent years. Although several studies have reported successful results in the internalization of micro- and nanoparticles in phagocytic cells, when nonphagocytic cells are used, the low internalization efficiency represents a limitation that needs to be overcome. [...]
2012 - 10.2147/IJN.S34635
International Journal of Nanomedicine, Vol. 7 (november 2012) , p. 5671-5682  
3.
12 p, 5.7 MB Intracellular CXCR4 + cell targeting with T22-empowered protein-only nanoparticles / Unzueta Elorza, Ugutz (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Céspedes, María Virtudes (CIBER de Bioingeniería, Biomateriales y Nanomedicina (Barcelona)) ; Ferrer Miralles, Neus (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Casanova, Isolda (CIBER de Bioingeniería, Biomateriales y Nanomedicina (Barcelona)) ; Cedano, Juan (Laboratory of Immunology, Regional Norte, Universidad de la Republica, Salto, Uruguay) ; Corchero, José Luis (Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina) ; Domingo-Espin, Joan (Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina) ; Villaverde Corrales, Antonio (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Mangues, Ramon (Centro de Investigación Biomédica en Red de Bioingeniería, Biomateriales y Nanomedicina) ; Vázquez Gómez, Esther (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia
Cell-targeting peptides or proteins are appealing tools in nanomedicine and innovative medicines because they increase the local drug concentration and reduce potential side effects. CXC chemokine receptor 4 (CXCR4) is a cell surface marker associated with several severe human pathologies, including colorectal cancer, for which intracellular targeting agents are currently missing. [...]
2012 - 10.2147/IJN.S34450
International Journal of Nanomedicine, Vol. 7 (august 2012) , p. 4533-4544  

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