Dipòsit Digital de Documents de la UAB 81 registres trobats  1 - 10següentfinal  anar al registre: La cerca s'ha fet en 0.02 segons. 
1.
17 p, 1.2 MB Human α-galactosidase a mutants : Priceless tools to develop novel therapies for fabry disease / Modrego, Andrea (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Amaranto, Marilla (Universidad Nacional de Córdoba (Argentina)) ; Godino, Agustina (Universidad Nacional de Córdoba (Argentina)) ; Mendoza, Rosa (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Barra, José Luis (Universidad Nacional de Córdoba (Argentina)) ; Corchero Nieto, José Luis (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Fabry disease (FD) is a lysosomal storage disease caused by mutations in the gene for the α-galactosidase A (GLA) enzyme. The absence of the enzyme or its activity results in the accumulation of glycosphingolipids, mainly globotriaosylceramide (Gb3), in different tissues, leading to a wide range of clinical manifestations. [...]
2021 - 10.3390/ijms22126518
International journal of molecular sciences, Vol. 22, Issue 12 (June 2021) , art. 6518  
2.
16 p, 2.5 MB Seminal plasma, sperm concentration, and sperm-PMN interaction in the donkey : An in vitro model to study endometrial inflammation at post-insemination / Miró, Jordi (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ; Marín, Henar (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ; Papas, Marion (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ; Gacem, Sabrina (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ; Catalán, Jaime (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ; Yeste Oliveras, Marc (Universitat de Girona. Departament de Biologia Cel·lular)
In the donkey, artificial insemination (AI) with frozen-thawed semen is associated with low fertility rates, which could be partially augmented through adding seminal plasma (SP) and increasing sperm concentration. [...]
2020 - 10.3390/ijms21103478
International journal of molecular sciences, Vol. 21 Núm. 10 (february 2020) , p. 3478  
3.
18 p, 3.9 MB Understanding the molecular basis of 5-ht4 receptor partial agonists through 3d-qsar studies / Castro-Alvarez, Alejandro (Universidad de La Frontera. Facultad de Medicina) ; Chávez Ángel, Emigdio (Institut Català de Nanociència i Nanotecnologia) ; Nelson, Ronald (Universidad Católica del Norte. Departamento de Química)
Alzheimer's disease (AD) is a neurodegenerative disorder whose prevalence has an incidence in senior citizens. Unfortunately, current pharmacotherapy only offers symptom relief for patients with side effects such as bradycardia, nausea, and vomiting. [...]
2021 - 10.3390/ijms22073602
International journal of molecular sciences, Vol. 22, issue 7 (April 2021) , art. 3602  
4.
15 p, 1.7 MB Selecting subpopulations of high-quality protein conformers among conformational mixtures of recombinant bovine MMP-9 solubilized from inclusion bodies / Carratalá, José Vicente (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Gifre-Renom, Laia (Institut de Recerca i Tecnologia Agroalimentàries. Departament de Producció de Remugants) ; Roca-Pinilla, Ramon (Institut de Recerca i Tecnologia Agroalimentàries. Departament de Producció de Remugants) ; Villaverde Corrales, Antonio (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Arís i Giralt, Anna (Institut de Recerca i Tecnologia Agroalimentàries. Departament de Producció de Remugants) ; García Fruitós, Elena (Institut de Recerca i Tecnologia Agroalimentàries. Departament de Producció de Remugants) ; Sanchez, Julieta M. (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Ferrer Miralles, Neus (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí")
A detailed workflow to analyze the physicochemical characteristics of mammalian matrix metalloproteinase (MMP-9) protein species obtained from protein aggregates (inclusion bodies-IBs) was followed. MMP-9 was recombinantly produced in the prokaryotic microbial cell factories Clearcoli (an engineered form of Escherichia coli) and Lactococcus lactis, mainly forming part of IBs and partially recovered under non-denaturing conditions. [...]
2021 - 10.3390/ijms22063020
International journal of molecular sciences, Vol. 22, Issue 6 (March 2021) , art. 3020  
5.
21 p, 3.0 MB Kisspeptin influences the reproductive axis and circulating levels of micrornas in senegalese sole / Oliveira, Catarina (University of Algarve. Center of Marine Sciences) ; Fatsini, Elvira (University of Algarve. Center of Marine Sciences) ; Fernández, Ignacio (Instituto Tecnológico Agrario de Castilla y León) ; Anjos, Catarina (University of Algarve. Center of Marine Sciences) ; Chauvigné, François (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Cerdà, Joan (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Mjelle, Robin (Nord University. Faculty of Bioscience and Aquaculture) ; Fernandes, Jorge (Nord University. Faculty of Bioscience and Aquaculture) ; Cabrita, Elsa (University of Algarve. Center of Marine Sciences)
Kisspeptin regulates puberty and reproduction onset, acting upstream of the brain-pituitary-gonad (HPG) axis. This study aimed to test a kisspeptin-based hormonal therapy on cultured Senegalese sole (G1) breeders, known to have reproductive dysfunctions. [...]
2020 - 10.3390/ijms21239051
International journal of molecular sciences, Vol. 21, Issue 23 (December 2020) , art. 9051  
6.
21 p, 5.3 MB Pathological ATX3 Expression Induces Cell Perturbations in E. coli as Revealed by Biochemical and Biophysical Investigations / Ami, Diletta (University of Milano-Bicocca. Department of Biotechnologies and Biosciences) ; Mereghetti, Paolo (Bioinformatics Consultant) ; Falvo, Jacopo (University of Milano-Bicocca. Department of Biotechnologies and Biosciences) ; Catelani, Tiziano (University of Milano-Bicocca. Department of Biotechnologies and Biosciences) ; Visentin, Cristina (Università degli Studi di Milano. Department of Biosciences) ; Tortora, Paolo (University of Milano-Bicocca. Department of Biotechnologies and Biosciences) ; Ventura, Salvador (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Natalello, Antonino (University of Milano-Bicocca. Departament of Biotechnology and Biosciences) ; Regonesi, Maria Elena (Università di Milano-Bicocca. Dipartimento di Biotecnologie e Bioscienze) ; Sciandrone, Barbara (University of Milano-Bicocca. Department of Biotechnologies and Biosciences)
Amyloid aggregation of human ataxin-3 (ATX3) is responsible for spinocerebellar ataxia type 3, which belongs to the class of polyglutamine neurodegenerative disorders. It is widely accepted that the formation of toxic oligomeric species is primarily involved in the onset of the disease. [...]
2021 - 10.3390/ijms22020943
International journal of molecular sciences, Vol. 22, Issue 2 (January 2021) , art. 943  
7.
13 p, 2.2 MB Epigenetic regulation of gfi1 in endocrine-related cancers : A role regulating tumor growth / Ashour, N. (Departamento de Biología de Sistemas. Unidad Docente de Bioquímica y Biología Molecular. Universidad de Alcalá) ; Angulo, J.C. (Hospital Universitario de Getafe (Madrid)) ; González-Corpas, A. (Departamento de Biología de Sistemas. Unidad Docente de Bioquímica y Biología Molecular. Universidad de Alcalá) ; Orea, M.J. (Departamento de Biología de Sistemas. Unidad Docente de Bioquímica y Biología Molecular. Universidad de Alcalá) ; Lobo, M.V.T. (Departamento de Biomedicina y Biotecnología. Universidad de Alcalá. Instituto Ramón y Cajal de Investigaciones Sanitarias (IRYCIS)) ; Colomer, R. (Universidad Autónoma de Madrid. Departamento de Medicina) ; Colás, B. (Departamento de Biología de Sistemas. Unidad Docente de Bioquímica y Biología Molecular. Universidad de Alcalá) ; Esteller, M. (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Ropero, S. (Departamento de Biología de Sistemas. Unidad Docente de Bioquímica y Biología Molecular. Universidad de Alcalá) ; Universitat Autònoma de Barcelona
Prostate and breast cancer constitute the most common cancers among men and women worldwide. The aging population is one of the main risk factors for prostate and breast cancer development and accumulating studies link aging with epigenetic changes. [...]
2020 - 10.3390/ijms21134687
International journal of molecular sciences, Vol. 21 Núm. 13 (july 2020) , p. 1-12  
8.
31 p, 1.0 MB Senescence in the development and response to cancer with immunotherapy : A double-edged sword / Battram, A.M. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Bachiller, M. (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Martín-Antonio, B. (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Universitat Autònoma de Barcelona
Cellular senescence was first described as a physiological tumor cell suppressor mechanism that leads to cell growth arrest with production of the senescence-associated secretory phenotype known as SASP. [...]
2020 - 10.3390/ijms21124346
International journal of molecular sciences, Vol. 21 Núm. 12 (february 2020) , p. 1-31  
9.
16 p, 2.8 MB Anti-Trypanosoma cruzi Activity of Metabolism Modifier Compounds / Martinez-Peinado, Nieves (Institut de Salut Global de Barcelona) ; Cortes-Serra, Nuria (Institut de Salut Global de Barcelona) ; Sherman, Julian (New York University School of Medicine. Department of Microbiology) ; Rodriguez, Ana (New York University School of Medicine. Department of Microbiology) ; Gascón, Joaquim (Institut de Salut Global de Barcelona) ; Alberola, Jordi (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ; Pinazo, Maria-Jesus (Institut de Salut Global de Barcelona) ; Rodríguez-Cortés, Alhelí (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ; Alonso-Padilla, Julio (Institut de Salut Global de Barcelona) ; Martori Muntsant, Clara (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia)
Chagas disease is caused by the protozoan parasite Trypanosoma cruzi and affects over 6 million people worldwide. Development of new drugs to treat this disease remains a priority since those currently available have variable efficacy and frequent adverse effects, especially during the long regimens required for treating the chronic stage of the disease. [...]
2021 - 10.3390/ijms22020688
International journal of molecular sciences, Vol. 22 Núm. 2 (2021) , p. 688  
10.
18 p, 2.2 MB GH/IGF-1 Abnormalities and Muscle Impairment : from basic research to clinical practice / Biagetti, Betina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Simó Canonge, Rafael (Hospital Universitari Vall d'Hebron. Institut de Recerca)
The impairment of skeletal muscle function is one of the most debilitating least understood co-morbidity that accompanies acromegaly (ACRO). Despite being one of the major determinants of these patients' poor quality of life, there is limited evidence related to the underlying mechanisms and treatment options. [...]
2021 - 10.3390/ijms22010415
International journal of molecular sciences, Vol. 22 Núm. 1 (2021) , p. 415  

Dipòsit Digital de Documents de la UAB : 81 registres trobats   1 - 10següentfinal  anar al registre:
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