Depósito Digital de Documentos de la UAB Encontrados 52 registros  1 - 10siguientefinal  ir al registro: La búsqueda tardó 0.02 segundos. 
1.
22 p, 4.3 MB Cerium oxide nanoparticles protect against oxidant injury and interfere with oxidative mediated kinase signaling in human-derived hepatocytes / Carvajal, Silvia (Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)) ; Perramón, Meritxell (Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)) ; Casals, Gregori (Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)) ; Oró, Denise (Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)) ; Ribera, Jordi (Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)) ; Morales Ruiz, Manuel (Universitat de Barcelona. Departament de Biomedicina) ; Casals, Eudald (Wuyi University. School of Biotechnology and Health Sciences) ; Casado, Pedro (Queen Mary University of London) ; Melgar Lesmes, Pedro (Universitat de Barcelona. Departament de Biomedicina) ; Fernández Varo, Guillermo (Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)) ; Cutillas, Pedro (Queen Mary University of London) ; Puntes, Víctor (Institut Català de Nanociència i Nanotecnologia) ; Jiménez, Wladimiro (Universitat de Barcelona. Departament de Biomedicina)
Cerium oxide nanoparticles (CeO NPs) possess powerful antioxidant properties, thus emerging as a potential therapeutic tool in non-alcoholic fatty liver disease (NAFLD) progression, which is characterized by a high presence of reactive oxygen species (ROS). [...]
2019 - 10.3390/ijms20235959
International journal of molecular sciences, Vol. 20, Issue 23 (December 2019) , art. 5959  
2.
19 p, 4.0 MB Protein phosphatase Ppz1 is not regulated by a hal3-like protein in plant pathogen ustilago maydis / Zhang, Chunyi (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; de la Torre, Antonio. (Consejo Superior de Investigaciones Científicas (Espanya). Instituto de Biología Funcional y Genómica (CSIC)) ; Pérez Martín, José (Consejo Superior de Investigaciones Científicas (Espanya). Instituto de Biología Funcional y Genómica (CSIC)) ; Ariño Carmona, Joaquín (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular)
Ppz enzymes are type-1 related Ser/Thr protein phosphatases that are restricted to fungi. In S. cerevisiae and other fungi, Ppz1 is involved in cation homeostasis and is regulated by two structurally-related inhibitory subunits, Hal3 and Vhs3, with Hal3 being the most physiologically relevant. [...]
2019 - 10.3390/ijms20153817
International journal of molecular sciences, Vol. 20, issue 15 (2019) , art. 3817  
3.
16 p, 4.3 MB Ischemic postconditioning reduces reperfusion arrhythmias by adenosine receptors and protein kinase C activation but is independent of KATP channels or connexin 43 / Diez, E.R. (Institute of Medical and Experimental Biology of Cuyo. CONICET) ; Sánchez, J.A. (Universitat Autònoma de Barcelona. Departament de Medicina) ; Prado, N.J. (Institute of Medical and Experimental Biology of Cuyo. CONICET) ; Zumino, A.Z.P. (Institute of Medical and Experimental Biology of Cuyo. CONICET) ; García-Dorado, D. (Universitat Autònoma de Barcelona. Departament de Medicina) ; Miatello, R.M. (Institute of Medical and Experimental Biology of Cuyo. CONICET) ; Rodríguez-Sinovas, A. (Centro de Investigación Biomédica en Red sobre Enfermedades Cardiovasculares (CIBERCV))
Ischemic postconditioning (IPoC) reduces reperfusion arrhythmias but the antiarrhythmic mechanisms remain unknown. The aim of this study was to analyze IPoC electrophysiological effects and the role played by adenosine A, A and A receptors, protein kinase C, ATP-dependent potassium (K) channels, and connexin 43. [...]
2019 - 10.3390/ijms20235927
International journal of molecular sciences, Vol. 20 Núm. 23 (january 2019) , p. 5927  
4.
13 p, 1.8 MB Extracellular albumin covalently sequesters selenocompounds and determines cytotoxicity / Zheng, Wenyi (Karolinska Institute Stockholm. Department of Laboratory Medicine) ; Boada, Roberto (Universitat Autònoma Barcelona. Departament de Química) ; He, Riu (Karolinska Institute Stockholm. Department of Laboratory Medicine) ; Xiao, Tingting (Universitat Autònoma Barcelona. Departament de Química) ; Ye, Fei (Kungliga Tekniska högskolan. Division of Functional Nanomaterials) ; Simonelli, Laura (ALBA Laboratori de Llum de Sincrotró) ; Valiente Malmagro, Manuel (Universitat Autònoma de Barcelona. Departament de Química) ; Zhao, Ying (Karolinska Institute Stockholm. Department of Laboratory Medicine) ; Hassan, Moustapha (Karolinska Institute Stockholm. Department of Laboratory Medicine)
Selenocompounds (SeCs) are well-known nutrients and promising candidates for cancer therapy; however, treatment efficacy is very heterogeneous and the mechanism of action is not fully understood. Several SeCs have been reported to have albumin-binding ability, which is an important factor in determining the treatment efficacy of drugs. [...]
2019 - 10.3390/ijms20194734
International journal of molecular sciences, Vol. 20, issue 19 (Oct. 2019) , art. 4734  
5.
25 p, 1.3 MB How plants handle trivalent (+3) elements / Poschenrieder, Charlotte (Universitat Autònoma de Barcelona. Laboratori de Fisiologia Vegetal) ; Busoms González, Sílvia (University of Nottingham. Plant Sciences, Future Food Beacon of Excellence) ; Barceló Coll, Juan (Universitat Autònoma de Barcelona. Laboratori de Fisiologia Vegetal)
Plant development and fitness largely depend on the adequate availability of mineral elements in the soil. Most essential nutrients are available and can be membrane transported either as mono or divalent cations or as mono-or divalent anions. [...]
2019 - 10.3390/ijms20163984
International journal of molecular sciences, Vol. 20, Issue 16 (August 2019) , art. 3984  
6.
18 p, 3.9 MB Gpathfinder : Identification of ligand-binding pathways by a multi-objective genetic algorithm / Sánchez Aparicio, José Emilio (Universitat Autònoma de Barcelona. Departament de Química Universitat Autònoma de Barcelona) ; Sciortino, Giuseppe (Universitat Autònoma de Barcelona. Departament de Química) ; Viladrich Herrmannsdoerfer, Daniel (Universitat Autònoma de Barcelona. Departament de Química) ; Orenes Chueca, Pablo (Universitat Autònoma de Barcelona. Departament de Química) ; Rodríguez-Guerra Pedregal, Jaime (Universitat Autònoma de Barcelona. Departament de Química) ; Maréchal, Jean-Didier (Universitat Autònoma de Barcelona. Departament de Química)
Protein-ligand docking is a widely used method to generate solutions for the binding of a small molecule with its target in a short amount of time. However, these methods provide identification of physically sound protein-ligand complexes without a complete view of the binding process dynamics, which has been recognized to be a major discriminant in binding affinity and ligand selectivity. [...]
2019 - 10.3390/ijms20133155
International journal of molecular sciences, Vol. 20, Issue 13 (July 2019) , art. 3155  
7.
25 p, 3.0 MB Distinct dopamine D2 receptor antagonists differentially impact D2 receptor oligomerization / Wouters, Elise (Laboratory of Toxicology. Department of Bioanalysis. Faculty of Pharmaceutical Sciences. Ghent University) ; Ricarte Marín, Adrián (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Dalton, James Andrew Rupert (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Giraldo, Jesús (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Stove, Christophe. (Laboratory of Toxicology. Department of Bioanalysis. Faculty of Pharmaceutical Sciences. Ghent University)
Dopamine D receptors (DR) are known to form transient homodimer complexes, of which the increased formation has already been associated with development of schizophrenia. Pharmacological targeting and modulation of the equilibrium of these receptor homodimers might lead to a better understanding of the critical role played by these complexes in physiological and pathological conditions. [...]
2019 - 10.3390/ijms20071686
International journal of molecular sciences, Vol. 20 Núm. 7 (january 2019) , p. 1686  
8.
11 p, 2.2 MB The membrane proximal domain of TRPV1 and TRPV2 channels mediates protein-protein interactions and lipid binding in vitro / Doñate Macián, Pau (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Álvarez Marimon, Elena (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Sepulcre, Francesc (Universitat Politècnica de Catalunya. Departament d'Enginyeria Agroalimentària i Biotecnologia) ; Vázquez Ibar, José Luis (Institut des Sciences du Vivant Frédéric-JOLIOT. CEA-Saclay) ; Perálvarez Marín, Alex (Institut de Neurociències)
Constitutive or regulated membrane protein trafficking is a key cell biology process. Transient receptor potential channels are somatosensory proteins in charge of detecting several physical and chemical stimuli, thus requiring fine vesicular trafficking. [...]
2019 - 10.3390/ijms20030682
International journal of molecular sciences, Vol. 20, Issue 3 (February 2019) , art. 682  
9.
14 p, 1.9 MB The effects of cobalt protoporphyrin IX and tricarbonyldichlororuthenium (II) dimer treatments and its interaction with nitric oxide in the locus coeruleus of mice with peripheral inflammation / Moreno, P. (Institut d'Investigació Biomèdica Sant Pau) ; Cazuza, R.A. (Department of Psychology. University of São Paulo) ; Gomes-Mendes, J. (Department of Psychology. University of São Paulo) ; Díaz, A.F. (Institut de Neurociències. Universitat Autònoma de Barcelona) ; Polo, S. (Institut de Neurociències. Universitat Autònoma de Barcelona) ; Leánez, S. (Institut de Neurociències. Universitat Autònoma de Barcelona) ; Leite-Panissi, C.R.A. (Department of Psychology. University of São Paulo) ; Pol, Olga. (Institut de Neurociències. Universitat Autònoma de Barcelona)
Heme oxygenase 1 (HO-1) and carbon monoxide were shown to normalize oxidative stress and inflammatory reactions induced by neuropathic pain in the central nervous system, but their effects in the locus coeruleus (LC) of animals with peripheral inflammation and their interaction with nitric oxide are unknown. [...]
2019 - 10.3390/ijms20092211
International journal of molecular sciences, Vol. 20, Issue 9 (January 2019) , p. 2211  
10.
24 p, 3.0 MB Insight into the Antifungal Mechanism of Action of Human RNase N-terminus Derived Peptides / Salazar Montoya, Vivian Angélica (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular.) ; Arranz Trullén, Javier (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Prats Ejarque, Guillem (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Torrent Burgas, Marc (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Andreu, D. (Universitat Pompeu Fabra. Departament de Ciències Experimentals i de la Salut) ; Pulido Gomez, David (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Boix i Borràs, Esther (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
Candida albicans is a polymorphic fungus responsible for mucosal and skin infections. Candida cells establish themselves into biofilm communities resistant to most currently available antifungal agents. [...]
2019 - 10.3390/ijms20184558
International journal of molecular sciences, Vol. 20, Issue 18 (September 2019) , art.4558  

Depósito Digital de Documentos de la UAB : Encontrados 52 registros   1 - 10siguientefinal  ir al registro:
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