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1.
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7 p, 2.4 MB |
Experimental transmission to a calf of an isolate of Spanish classical scrapie
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Rosa Bolea (Universidad de Zaragoza. Centro de Investigación en Encefalopatías y Enfermedades Transmisibles Emergentes) ;
Carlos Hedman (Universidad de Zaragoza. Centro de Investigación en Encefalopatías y Enfermedades Transmisibles Emergentes) ;
Óscar López-Pérez (Universidad de Zaragoza. Centro de Investigación en Encefalopatías y Enfermedades Transmisibles Emergentes) ;
Belén Marín (Universidad de Zaragoza. Centro de Investigación en Encefalopatías y Enfermedades Transmisibles Emergentes) ;
Vidal Barba, Enric (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ;
Pumarola i Batlle, Martí (Universitat Autònoma de Barcelona. Departament de Medicina i Cirurgia Animals) ;
Fabien Corbière (Ecole Nationale Vétérinaire de Toulouse) ;
Antonio Romero (Universidad de Zaragoza) ;
Bernardino Moreno (Universidad de Zaragoza. Centro de Investigación en Encefalopatías y Enfermedades Transmisibles Emergentes) ;
Inmaculada Martín-Burriel (Universidad de Zaragoza. Centro de Investigación en Encefalopatías y Enfermedades Transmisibles Emergentes) ;
Olivier Andréoletti (Ecole Nationale Vétérinaire de Toulouse) ;
Juan José Badiola (Universidad de Zaragoza. Centro de Investigación en Encefalopatías y Enfermedades Transmisibles Emergentes)
Multiple theories exist regarding the origin of bovine spongiform encephalopathy (BSE). An early and prominent theory proposed that BSE was the result of the adaptation of sheep scrapie to cattle. The reports to date indicate that the distribution of the pathological prion protein (PrPSc) in experimental bovine scrapie is largely restricted to the central nervous system (CNS). [...]
2017
The Journal of general virology, Vol. 98 Núm. 10 (2017) , p. 2628-2634
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2.
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22 p, 639.2 KB |
Viral culture and immunofluorescence for the detection of SARS-CoV-2 infectivity in RT-PCR positive respiratory samples
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Berengua, Carla (Institut d'Investigació Biomèdica Sant Pau) ;
López Ruiz, Marina (Institut d'Investigació Biomèdica Sant Pau) ;
Esteban, Montserrat (Institut d'Investigació Biomèdica Sant Pau) ;
Marín, Pilar (Institut d'Investigació Biomèdica Sant Pau) ;
Ramos, Paula (Institut d'Investigació Biomèdica Sant Pau) ;
del Cuerpo Casas, Margarita (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Gich, Ignasi (Institut d'Investigació Biomèdica Sant Pau) ;
Navarro Risueño, Ferran (Institut d'Investigació Biomèdica Sant Pau) ;
Miró, Elisenda (Institut d'Investigació Biomèdica Sant Pau) ;
Rabella, Núria (Institut d'Investigació Biomèdica Sant Pau)
Background: Knowing how long SARS-CoV-2-positive individuals can remain infective is crucial for the design of infection prevention and control strategies. Viral culture is the gold standard for detecting an active-replicative virus and evaluating its infectious potential. [...]
2022 -  10.1016/j.jcv.2022.105167
Journal of Clinical Virology, Vol. 152 (July 2022) , art. 105167
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3.
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2 p, 530.8 KB |
ICTV Virus Taxonomy Profile : Potyviridae 2022
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Inoue-Nagata, Alice K. (Embrapa Vegetables) ;
Jordan, Ramon (U.S. Department of Agriculture (USDA)) ;
Kreuze, Jan (International Potato Center (CIP)) ;
Li, Fan (Yunnan Agricultural University) ;
Lopez-Moya, Juan Jose (Centre de Recerca en Agrigenòmica) ;
Mäkinen, Kristiina (University of Helsinki) ;
Ohshima, Kazusato (Saga University) ;
Wylie, Stephen (Murdoch University) ;
ICTV Report Consortium
The family Potyviridae includes plant viruses with single-stranded, positive-sense RNA genomes of 8-11 kb and flexuous filamentous particles 650-950 nm long and 11-20 nm wide. Genera in the family are distinguished by the host range, genomic features and phylogeny of the member viruses. [...]
2022 - 10.1099/jgv.0.001738
The Journal of general virology, Vol. 103, Issue 5 (May 2022)
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4.
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17 p, 3.2 MB |
Sirtuin-2, NAD-Dependent Deacetylase, Is a New Potential Therapeutic Target for HIV-1 Infection and HIV-Related Neurological Dysfunction
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Duran-Castells, Clara (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Llano Montero, Anuska (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Kawana-Tachikawa, Ai (National Institute of Infectious Diseases (Tokio)) ;
Prats, Anna (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Martinez-Zalacain, Ignacio (Institut d'Investigació Biomèdica de Bellvitge) ;
Kobayashi-Ishihara, Mie (Universitat Pompeu Fabra) ;
Oriol-Tordera, Bruna (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Peña, Ruth (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Gálvez, Cristina (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Silva-Arrieta, Sandra (Silva-Arrieta, Sandra) ;
Clotet Sala, Bonaventura (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Riveira-Muñoz, Eva (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Ballana, Ester (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Prado, Julia G. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Martínez Picado, Francisco Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Sanchez, Jorge (Centro de Investigaciones Tecnologicas Biomedicas y Medioambientales (Perú)) ;
Mothe, Beatriz (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Hartigan-O'Connor, Dennis (University of California. Department of Medical Microbiology and Immunology) ;
Wyss-Coray, Tony (Stanford University School of Medicine. Department of Neurology and Neurological Science) ;
Meyerhans, Andreas (University of Gothenburg. Department of Infectious Diseases) ;
Gisslén, Magnus (University of Gothenburg. Department of Infectious Diseases) ;
Price, Richard W. (University of California San Francisco. Department of Neurology) ;
Soriano-Mas, Carles (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de Ciències de la Salut) ;
Muñoz-Moreno, José Antonio (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Brander, Christian (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Ruiz Riol, Marta (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa)
The implementation and access to combined antiretroviral treatment (cART) have dramatically improved the quality of life of people living with HIV (PLWH). However, some comorbidities, such as neurological disorders associated with HIV infection still represent a serious clinical challenge. [...]
2023 - 10.1128/jvi.01655-22
Journal of Virology, Vol. 97 (January 2023)
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5.
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17 p, 1.8 MB |
BA71ΔCD2 : a New Recombinant Live Attenuated African Swine Fever Virus with Cross-Protective Capabilities
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Monteagudo, Paula L. (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Lacasta, Anna (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
López, Elisabeth (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Bosch Camós, Laia (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Collado Miguens, Javier Alonso (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Pina-Pedrero, Sonia (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Correa-Fiz, Florencia (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Accensi Alemany, Francesc (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals) ;
Navas, María Jesús (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Vidal Barba, Enric (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal) ;
Bustos, María J. (Centro de Biología Molecular Severo Ochoa) ;
Rodríguez, Javier M. (Centro Nacional de Microbiología (Espanya)) ;
Gallei, Andreas (Boehringer Ingelheim Veterinary Research Center) ;
Nikolin, Veljko (Boehringer Ingelheim Veterinary Research Center) ;
Salas, María L. (Centro de Biología Molecular Severo Ochoa) ;
Rodriguez, Fernando (Institut de Recerca i Tecnologia Agroalimentàries. Centre de Recerca en Sanitat Animal)
African swine fever is a highly contagious viral disease of mandatory declaration to the World Organization for Animal Health (OIE). The lack of available vaccines makes its control difficult; thus, African swine fever virus (ASFV) represents a major threat to the swine industry. [...]
2017 - 10.1128/JVI.01058-17
Journal of Virology, Vol. 91 (october 2017)
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6.
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10 p, 2.2 MB |
A European multicentre evaluation of detection and typing methods for human enteroviruses and parechoviruses using RNA transcripts
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Hayes, A. (University of Oxford) ;
Nguyen, D. (University of Oxford) ;
Andersson, M. (John Radcliffe Hospital (Oxford, Regne Unit)) ;
Antón, Andrés (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Bailly, Jean-Luc (Université Clermont Auvergne) ;
Beard, S. (National Infection Service, Public Health England) ;
Benschop, K. S. M. (National Institute for Public Health and the Environment (RIVM), The Netherlands.) ;
Berginc, N. (National Laboratory of Health, Environment and Food, Ljubljana, Slovenia.) ;
Blomqvist, S. (National Institute for Health and Welfare, Finland.) ;
Cunningham, E. (St. Thomas' Hospital, London, UK.) ;
Davis, D. (Great Ormond Street Hospital for Children (Londres)) ;
Dembinski, J. L. (Norwegian Institute of Public Health) ;
Diedrich, S. (Robert Koch Institute, Berlin, Germany.) ;
Dudman, Susanne (University of Oslo) ;
Dyrdak, R. (Karolinska University Hospital and Karolinska Institutet (Suècia)) ;
Eltringham, G. J. A. (Freeman Hospital, Newcastle Upon Tyne, UK.) ;
Gonzales-Goggia, S. (National Infection Service, Public Health England) ;
Gunson, R. (Glasgow Royal Infirmary) ;
Howson-Wells, H. C. (Nottingham University Hospitals NHS Trust (Regne Unit)) ;
Jääskeläinen, A. J. (Helsinki University Hospital (Finlàndia)) ;
López-Labrador, F. X. (Fundació per al Foment de la Investigació Sanitària i Biomèdica de la Comunitat Valenciana (Fisabio)) ;
Maier, M. (Leipzig University Hospital) ;
Majumdar, M. (The National Institute for Biological Standards and Control, Hertfordshire, UK.) ;
Midgley, S. (Statens Serum Institut, Copenhagen, Denmark.) ;
Mirand, A. (CHU Clermont-Ferrand) ;
Morley, U. (University College Dublin) ;
Nordbø, S. A. (St Olav's University Hospital) ;
Oikarinen, S. (Tampere University, Finland.) ;
Osman, H. (Heartlands Hospital, Birmingham, UK.) ;
Papa, A. (Aristotle University of Thessaloniki) ;
Pellegrinelli, L. (University of Milan) ;
Piralla, A. (Fondazione IRCCS Policlinico San Matteo, Pavia.) ;
Rabella, Núria (Institut d'Investigació Biomèdica Sant Pau) ;
Richter, Jan (Cyprus Institute of Neurology and Genetics) ;
Smith, M. (King's College Hospital NHS Foundation Trust) ;
Söderlund Strand, A. (Lund University Hospital, Sweden.) ;
Templeton, K. (Royal Infirmary of Edinburgh) ;
Vipond, B. (Southmead Hospital, Bristol, UK.) ;
Vuorinen, T. (Turku University Hospital (Finlàndia)) ;
Williams, C. (Royal Oldham Hospital, UK.) ;
Wollants, E. (REGA Institute, Leuven, Belgium.) ;
Zakikhany, K. (Katherina Zakikhany-Gilg, Public Health Agency of Sweden) ;
Fischer, T. K. (Statens Serum Institut, Copenhagen, Denmark.) ;
Harvala, H. (NHS Blood and Transplant, UK.) ;
Simmonds, Peter (University of Oxford) ;
Universitat Autònoma de Barcelona
Polymerase chain reaction (PCR) detection has become the gold standard for diagnosis and typing of enterovirus (EV) and human parechovirus (HPeV) infections. Its effectiveness depends critically on using the appropriate sample types and high assay sensitivity as viral loads in cerebrospinal fluid samples from meningitis and sepsis clinical presentation can be extremely low. [...]
2020 - 10.1002/jmv.25659
Journal of Medical Virology, Vol. 92 (january 2020) , p. 1065-1074
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6 p, 619.9 KB |
Hepatitis C virus intrinsic molecular determinants may contribute to the development of cholestatic hepatitis after liver transplantation
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Gambato, Martina (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Gregori i Font, Josep (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Quer, Josep 1963- (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Koutsoudakis, George (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
González, Patricia (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Caro-Pérez, Noelia (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Garcia-Cehic, D. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
García-González, Neris (Joint Research Unit Infección y Salud Pública. FISABIO-Universitat de Valéncia) ;
González-Candelas, Fernando (Joint Research Unit Infección y Salud Pública. FISABIO-Universitat de Valéncia) ;
Ignacio Esteban, Juan (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Crespo, Gonzalo (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Navasa, Miquel (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Forns, Xavier (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Pérez-Del-Pulgar, Sofía (Institut d'Investigacions Biomèdiques August Pi i Sunyer)
Cholestatic hepatitis C (CHC) is a severe form of hepatitis C virus (HCV) infection recurrence that leads to high graft loss rates early after liver transplantation (LT). To investigate the pathogenic mechanisms of CHC, we analysed HCV quasispecies in CHC patients compared to a control group (mild hepatitis C recurrence) by deep pyrosequencing. [...]
2019 - 10.1099/jgv.0.001175
The Journal of general virology, Vol. 100 Núm. 1 (january 2019) , p. 63-68
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15 p, 2.1 MB |
Novel class of viral ankyrin proteins targeting the host E3 ubiquitin ligase Cullin-2
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Odon, Valerie (University of Surrey. Department of Microbial Sciences) ;
Georgana, Iliana (University of Surrey. Department of Microbial Sciences) ;
Holley, Joe (University of Surrey. Department of Microbial Sciences) ;
Morata, Jordi (Centre de Recerca en Agrigenòmica) ;
Maluquer De Motes, Carlos (University of Surrey. Department of Microbial Sciences)
Ankyrin repeat (ANK) domains are among the most abundant motifs in eukaryotic proteins. ANK proteins are rare amongst viruses, with the exception of poxviruses, which presumably acquired them from the host via horizontal gene transfer. [...]
2018 - 10.1128/JVI.01374-18
Journal of Virology, Vol. 92, Issue 23 (December 2018) , art. e01374
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15 p, 676.0 KB |
Mechanisms of abrupt loss of virus control in a cohort of previous HIV controllers
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Rosás Umbert, Miriam (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Llano Montero, Anuska (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Bellido, Rocío (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Olvera, Alex (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Ruiz-Riol, Marta (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Rocafort, Muntsa (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Fernández, Marco A. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Cobarsi, Patricia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Crespo Casal, Manuel (Complexo Hospitalario Universitario de Vigo) ;
Dorrell, Lucy (Nuffield Department of Medicine, University of Oxford) ;
Del Romero, Jorge (Centro Sanitario Sandoval, Madrid) ;
Alcami, Jose (Instituto de Salud Carlos III) ;
Paredes, Roger (Universitat Autònoma de Barcelona. Departament de Medicina) ;
Brander, Christian (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Mothe, Beatriz (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa)
A few individuals can control HIV infection without the need for antiretroviral treatment and are referred to as HIV controllers. We have studied HIV controllers who suddenly lose this ability and present with high in vivo viral replication and decays in their CD4 + T-cell counts to identify potential immune and virological factors that were responsible for initial virus control. [...]
2019 - 10.1128/JVI.01436-18
Journal of Virology, Vol. 93 (february 2019)
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14 p, 2.0 MB |
Differential Immunodominance Hierarchy of CD8 + T-Cell Responses in HLA-B*27:05- and -B*27:02-Mediated Control of HIV-1 Infection
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Adland, Emily ;
Hill, Matilda ;
Lavandier, Nora ;
Csala, Anna ;
Edwards, Anne ;
Chen, Fabian ;
Radkowski, Marek ;
Kowalska, Justyna D. ;
Paraskevis, Dimitrios ;
Hatzakis, Angelos ;
Valenzuela-Ponce, Humberto ;
Pfafferott, Katja ;
Williams, Ian ;
Pellegrino, Pierre ;
Borrow, Persephone ;
Mori, Masahiko ;
Rockstroh, Jürgen ;
Prado, Julia G.. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Mothe, Beatriz (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Dalmau, Judith (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Martinez-Picado, Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Tudor-Williams, Gareth ;
Frater, John ;
Stryhn, Anette ;
Buus, Soren ;
Teran, Gustavo Reyes ;
Mallal, Simon ;
John, Mina ;
Buchbinder, Susan ;
Kirk, Gregory ;
Martin, Jeffrey ;
Michael, Nelson ;
Fellay, Jacques ;
Deeks, Steve ;
Walker, Bruce D ;
Avila-Rios, Santiago ;
Cole, David ;
Brander, Christian (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Carrington, Mary ;
Goulder, Philip ;
Universitat Autònoma de Barcelona
The well-characterized association between HLA-B*27:05 and protection against HIV disease progression has been linked to immunodominant HLA-B*27:05-restricted CD8 + T-cell responses toward the conserved Gag KK10 (residues 263 to 272) and polymerase (Pol) KY9 (residues 901 to 909) epitopes. [...]
2018 - 10.1128/JVI.01685-17
Journal of Virology, Vol. 92 (january 2018)
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