Depósito Digital de Documentos de la UAB Encontrados 15 registros  1 - 10siguiente  ir al registro: La búsqueda tardó 0.01 segundos. 
1.
10 p, 2.1 MB A short CD3/CD28 costimulation combined with IL-21 enhance the generation of human memory stem T cells for adoptive immunotherapy / Alvarez-Fernández, Carmen (Institut d'Investigació Biomèdica Sant Pau) ; Escribà Garcia, Laura (Institut d'Investigació Biomèdica Sant Pau) ; Vidal, Silvia (Institut d'Investigació Biomèdica Sant Pau) ; Sierra, Jorge (Universitat Autònoma de Barcelona) ; Briones Meijide, Javier (Universitat Autònoma de Barcelona) ; Universitat Autònoma de Barcelona
Immunotherapy based on the adoptive transfer of gene modified T cells is an emerging approach for the induction of tumor-specific immune responses. Memory stem T cells, due to their enhanced antitumor and self-renewal capacity, have become potential candidate for adoptive T cell therapy of cancer. [...]
2016 - 10.1186/s12967-016-0973-y
Journal of translational medicine, Vol. 14 (july 2016)  
2.
11 p, 1.3 MB Dendritic cells combined with tumor cells and α-galactosylceramide induce a potent, therapeutic and NK-cell dependent antitumor immunity in B cell lymphoma / Escribà Garcia, Laura (Institut d'Investigació Biomèdica Sant Pau) ; Alvarez-Fernández, Carmen (Institut d'Investigació Biomèdica Sant Pau) ; Tellez-Gabriel, Marta (Institut d'Investigació Biomèdica Sant Pau) ; Sierra, Jorge (Institut d'Investigació Biomèdica Sant Pau) ; Briones, Javier (Institut d'Investigació Biomèdica Sant Pau) ; Universitat Autònoma de Barcelona
Invariant natural killer T (iNKT) cells are a small population of lymphocytes with unique specificity for glycolipid antigens presented by non-polymorphic CD1d receptor on dendritic cells (DCs). iNKT cells play a central role in tumor immunology since they are implicated in the coordination of innate and adaptive immune responses. [...]
2017 - 10.1186/s12967-017-1219-3
Journal of translational medicine, Vol. 15 (may 2017)  
3.
10 p, 5.7 MB Stability enhancement of clinical grade multipotent mesenchymal stromal cell-based products / Mirabel, Clémentine (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Puente-Massaguer, Eduard (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental) ; del Mazo-Barbara, Anna (Banc de Sang i Teixits. Servei de Teràpia Cel·lular) ; Reyes, Blanca (Banc de Sang i Teixits. Servei de Teràpia Cel·lular) ; Morton, Philip (Albumedix Ltd (Nottingham)) ; Gòdia, Francesc (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental) ; Vives Armengol, Joaquim (Universitat Autònoma de Barcelona. Departament de Medicina)
Successful delivery of cell-based therapeutics into patients is compromised by their short shelf-life upon release from production facilities due to the living nature of the active component that rapidly loses viability, and therefore its properties. [...]
2018 - 10.1186/s12967-018-1659-4
Journal of translational medicine, Vol. 16 (october 2018)  
4.
8 p, 1.2 MB Glycemic variability : prognostic impact on acute ischemic stroke and the impact of corrective treatment for hyperglycemia. The GLIAS-III translational study / Fuentes, Blanca (Hospital Universitario La Paz (Madrid)) ; Pastor-Yborra, Silvia (Hospital Universitario La Paz (Madrid)) ; Gutiérrez-Zúñiga, Raquel (Hospital Universitario La Paz (Madrid)) ; González-Pérez de Villar, Noemí (Hospital Universitario La Paz (Madrid)) ; de Celis, Elena (Hospital Universitario La Paz (Madrid)) ; Rodríguez-Pardo, Jorge (Hospital Universitario La Paz (Madrid)) ; Gómez-de Frutos, Mari Carmen (Hospital Universitario La Paz (Madrid)) ; Laso-García, Fernando (Hospital Universitario La Paz (Madrid)) ; Gutiérrez-Fernández, María (Hospital Universitario La Paz (Madrid)) ; Ortega-Casarrubios, MÁngeles (Hospital Universitario 12 de Octubre (Madrid)) ; Soto, Alfonso (Complejo Hospitalario Universitario de A Coruña) ; López-Fernández, María (Complejo Hospitalario Universitario de A Coruña) ; Santamaría, María (Hospital Universitario La Paz (Madrid)) ; Díez-González, Noemí (Hospital Universitario de Donostia.(Sant Sebastià, País Basc)) ; Freijo, Mar M. (Instituto de Investigación Sanitaria Biocruces Bizkaia) ; Zandio, Beatriz (Complejo Hospitalario de Navarra) ; Delgado-Mederos, Raquel (Institut d'Investigació Biomèdica Sant Pau) ; Calleja, Ana (Hospital Clínico Universitario (Valladolid)) ; Portilla-Cuenca, Juan Carlos (Hospital San Pedro de Alcántara) ; Lisbona, Arturo (Hospital Universitario La Paz (Madrid)) ; Otero-Ortega, Laura (Hospital Universitario La Paz (Madrid)) ; Díez-Tejedor, Exuperio (Hospital Universitario La Paz (Madrid)) ; Universitat Autònoma de Barcelona
Glycemic variability (GV) represents the amplitude of oscillations in glucose levels over time and is associated with higher mortality in critically ill patients. Our aim is to evaluate the impact of GV on acute ischemic stroke (IS) outcomes in humans and explore the impact of two different insulin administration routes on GV in an animal model. [...]
2020 - 10.1186/s12967-020-02586-4
Journal of translational medicine, Vol. 18 (november 2020)  
5.
9 p, 1.7 MB Establishment of urinary exosome-like vesicles isolation protocol for FHHNC patients and evaluation of different exosomal RNA extraction methods / Vall-Palomar, Mònica. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Arévalo, J. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Ariceta Iraola, Gema (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Meseguer, A. (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
Molecular and cellular pathophysiological events occurring in the majority of rare kidney diseases remain to be elucidated. Familial hypomagnesemia with hypercalciuria and nephrocalcinosis (FHHNC) is a rare autosomal recessive disorder caused by mutations in either CLDN16 or CLDN19 genes. [...]
2018 - 10.1186/s12967-018-1651-z
Journal of translational medicine, Vol. 16 (october 2018)  
6.
14 p, 2.8 MB EV-associated miRNAs from peritoneal lavage as potential diagnostic biomarkers in colorectal cancer / Roman-Canal, Berta (Universitat Autònoma de Barcelona) ; Tarragona, Jordi (Institut de Recerca Biomèdica de Lleida) ; Moiola, Cristian Pablo (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Gatius, Sònia (Institut de Recerca Biomèdica de Lleida) ; Bonnin, Sarah (Centre for Genomic Regulation (CRG), The Barcelona Institute or Science and Technology) ; Ruiz-Miró, Maria (Institut de Recerca Biomèdica de Lleida) ; Sierra, José Enrique (Institut de Recerca Biomèdica) ; Rufas, Maria (Institut de Recerca Biomèdica) ; González, Esperanza (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ; Porcel, José M. (Institut de Recerca Biomèdica de Lleida) ; Gil-Moreno, Antonio (Hospital Universitari Vall d'Hebron) ; Falcón-Pérez, Juan M. (IKERBASQUE, Basque Foundation for Science) ; Ponomarenko, Julia (Universitat Pompeu Fabra) ; Matias-Guiu, Xavier (Institut de Recerca Biomèdica de Lleida) ; Colás Ortega, Eva (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Universitat Autònoma de Barcelona
Colorectal cancer (CRC) is the third leading cause of cancer-related mortality worldwide. Current systematic methods for diagnosing have inherent limitations so development of a minimally-invasive diagnosis, based on the identification of sensitive biomarkers in liquid biopsies could therefore facilitate screening among population at risk. [...]
2019 - 10.1186/s12967-019-1954-8
Journal of translational medicine, Vol. 17 (june 2019)  
7.
12 p, 854.3 KB Reduced heart rate variability predicts fatigue severity in individuals with chronic fatigue syndrome/myalgic encephalomyelitis / Escorihuela, Rosa M (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ; Capdevila Ortís, Lluís (Universitat Autònoma de Barcelona. Departament de Psicologia Bàsica, Evolutiva i de l'Educació) ; Castro, Juan Ramos (Universitat Politècnica de Catalunya. Departament d'Enginyeria Electrònica) ; Zaragozà, María Cleofé (Clinical Research Department, Laboratorios Viñas, Barcelona, Spain) ; Maurel, Sara (Universitat Autònoma de Barcelona. Departament de Medicina) ; Alegre Martín, José (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Castro-Marrero, Jesús (Hospital Universitari Vall d'Hebron. Institut de Recerca)
Heart rate variability (HRV) is an objective, non-invasive tool to assessing autonomic dysfunction in chronic fatigue syndrome/myalgic encephalomyelitis (CFS/ME). People with CFS/ME tend to have lower HRV; however, in the literature there are only a few previous studies (most of them inconclusive) on their association with illness-related complaints. [...]
2020 - 10.1186/s12967-019-02184-z
Journal of translational medicine, Vol. 18 (january 2020)  
8.
10 p, 1.6 MB Perrault syndrome with neurological features in a compound heterozygote for two TWNK mutations : Overlap of TWNK-related recessive disorders / Domínguez-Ruiz, M. (Centro de Investigación Biomédica en Red de Enfermedades Raras) ; García-Martínez, A. (Department of Neurology. Servicio de Neurología. Hospital Universitario Central de Asturias) ; Corral-Juan, Marc (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Pérez-Álvarez, Á.I. (Department of Neurology. Servicio de Neurología. Hospital Universitario Central de Asturias) ; Plasencia, A.M. (Servicio de Pediatría. Hospital Universitario Central de Asturias) ; Villamar, M. (Centro de Investigación Biomédica en Red de Enfermedades Raras) ; Moreno-Pelayo, M.A. (Centro de Investigación Biomédica en Red de Enfermedades Raras) ; Matilla-Dueñas, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Menéndez-González, M. (Department of Neurology. Servicio de Neurología. Hospital Universitario Central de Asturias) ; Del Castillo, I. (Centro de Investigación Biomédica en Red de Enfermedades Raras) ; Universitat Autònoma de Barcelona
Background: Perrault syndrome is a rare autosomal recessive disorder that is characterized by the association of sensorineural hearing impairment and ovarian dysgenesis in females, whereas males have only hearing impairment. [...]
2019 - 10.1186/s12967-019-2041-x
Journal of translational medicine, Vol. 17 Núm. 1 (28 2019) , p. 290  
9.
8 p, 964.1 KB Telomere attrition in heart failure : a flow-FISH longitudinal analysis of circulating monocytes / Teubel, Iris (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Elchinova, Elena Georgieva (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Rudilla, F (Madrid, Spain) ; Fernández, Marco A. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Gálvez-Montón, Carolina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Moliner, Pedro (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; de Antonio, Marta (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Lupón, Josep (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Bayés-Genís, Antoni (Universitat Autònoma de Barcelona. Departament de Medicina)
Cross-sectional investigations report shorter telomeres in patients with heart failure (HF); however, no studies describe telomere length (TL) trajectory and its relationship with HF progression. Here we aimed to investigate telomere shortening over time and its relationship to outcomes. [...]
2018 - 10.1186/s12967-018-1412-z
Journal of translational medicine, Vol. 16 (february 2018)  
10.
12 p, 3.0 MB Exosome-like vesicles in uterine aspirates : a comparison of ultracentrifugation-based isolation protocols / Campoy Moncayo, Irene (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Lanau, Lucia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Altadill, Tatiana (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Sequeiros, Tamara (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Cabrera, Silvia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Cubo-Abert, Montserrat (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Pérez-Benavente, Assumpción (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Garcia, Angel (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Borrós, Salvador (Universitat Ramon Llull. Institut Químic de Sarrià-IQS) ; Santamaria, Anna (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Ponce, Jordi (Hospital Universitari de Bellvitge) ; Matias-Guiu, Xavier (Institut de Recerca Biomèdica de Lleida) ; Reventós, Jaume (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Gil-Moreno, Antonio (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Rigau, Marina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Colás Ortega, Eva (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Universitat Autònoma de Barcelona
Uterine aspirates are used in the diagnostic process of endometrial disorders, yet further applications could emerge if its complex milieu was simplified. Exosome-like vesicles isolated from uterine aspirates could become an attractive source of biomarkers, but there is a need to standardize isolation protocols. [...]
2016 - 10.1186/s12967-016-0935-4
Journal of translational medicine, Vol. 14 (june 2016)  

Depósito Digital de Documentos de la UAB : Encontrados 15 registros   1 - 10siguiente  ir al registro:
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