UAB Digital Repository of Documents 69 records found  1 - 10nextend  jump to record: Search took 0.01 seconds. 
1.
10 p, 290.8 KB Alectinib versus crizotinib in untreated ALK-positive non–small-cell lung cancer / Peters, S. (Lausanne University Hospital) ; Camidge, D.R. (University of Colorado) ; Shaw, A.T. (Massachusetts General Hospital) ; Gadgeel, S. (University of Michigan) ; Ahn, J.S. (Samsung Medical Center. Sungkyunkwan University School of Medicine) ; Kim, D.W. (Seoul National University Hospital) ; Ou, S.H.I. (School of Medicine) ; Pérol, M. (Department of Medical Oncology. Léon Bérard Cancer Center) ; Dziadziuszko, R. (Department of Oncology and Radiotherapy. Medical University of Gdansk) ; Rosell, R. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Zeaiter, A. (F. Hoffmann–La Roche) ; Mitry, E. (F. Hoffmann–La Roche) ; Golding, S. (F. Hoffmann–La Roche) ; Balas, B. (F. Hoffmann–La Roche) ; Noe, J. (F. Hoffmann–La Roche) ; Morcos, P.N. (Roche Innovation Center) ; Mok, T. (State Key Laboratory of South China. Chinese University of Hong Kong)
BACKGROUND: Alectinib, a highly selective inhibitor of anaplastic lymphoma kinase (ALK), has shown systemic and central nervous system (CNS) efficacy in the treatment of ALK-positive non–small-cell lung cancer (NSCLC). [...]
2017 - 10.1056/NEJMoa1704795
New England Journal of Medicine, Vol. 377 Núm. 9 (31 2017) , p. 829-838  
2.
6 p, 1.9 MB Heart–lung–muscle anti-SAE syndrome : an atypical severe combination / Zamora Serrallonga, Elisabet (Universitat Autònoma de Barcelona. Departament de Medicina) ; Seder Colomina, Elena (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol. Servei de Cardiologia) ; Holgado Pérez, Susana (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol. Servei de Reumatologia) ; Quirant Sanchez, Bibiana (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol. Servei d'Immunologia) ; Mate Sanz, José Luis (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol. Servei de Patologia) ; Martínez Cáceres, Eva M. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Casafont Solé, Ivette (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol. Servei de Reumatologia) ; Bayés Genís, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol. Servei de Cardiologia)
A 78-year-old man with 3 months of progressive dyspnea, dysphony, dysgeusia, and proximal muscle weakness was diagnosed of probably idiopathic inflammatory myopathy with nonspecific interstitial pneumonia. [...]
2019 - 10.3390/jcm8010020
Journal of clinical medicine, Vol. 8, issue 1 (Jan. 2019) , art. 20  
3.
8 p, 1.9 MB Concentration-dependent protection by ethanol extract of propolis against γ-ray-induced chromosome damage in human blood lymphocytes / Montoro, A. (Universitat de Valencia. Área de Nutrición y Bromatología) ; Barquinero Estruch, Joan Francesc (Universitat Autònoma de Barcelona. Unitat d'Antropologia Biològica) ; Almonacid, Miguel (Hospital Universitario la Fe. Servicio de Protección Radiológica) ; Montoro, A. (Universitat de València. Área de Nutrición y Bromatología) ; Sebastià, N. (Universitat de València. Área de Nutrición y Bromatología) ; Verdù, G. (Universidad Politécnica de Valencia. Departamento de Ingeniería Química y Nuclear) ; Sahuquillo, V. (Servicio de Protección Radioĺgica. Hospital Universitario la Fe) ; Serrano, J. (Dietéticos Intersa) ; Saiz, M. (Dietéticos Intersa) ; Villaescusa, J.I. (Servicio de Protección Radioĺgica. Hospital Universitario la Fe) ; Soriano, J.M. (Universitat de València. Área de Nutrición y Bromatología)
Radioprotection with natural products may be relevant to the mitigation of ionizing radiation-induced damage in mammalian systems; in this sense, propolis extracts have shown effects such as antioxidant, antitumoral, anti-inflammatory, and immunostimulant. [...]
2011 - 10.1155/2011/174853
Evidence-based Complementary and Alternative Medicine, Vol. 2011 (2011) , art. 174853  
4.
7 p, 1.8 MB Semimembranosus Muscle Injuries In Sport. A Practical MRI use for Prognosis / Balius, Ramon (Clinica Diagonal. Sports Medicine and Imaging) ; Bossy, Mireia (Centros Medicos Creu Blanca) ; Pedret, Carles (Clinica Diagonal. Sports Medicine and Imaging) ; Capdevila Ortís, Lluís (Universitat Autònoma de Barcelona. Departament de Psicologia Bàsica, Evolutiva i de l'Educació) ; Alomar, Xavier (Centres Mèdics Creu Blanca. Departament de Radiologia) ; Heiderscheit, Bryan (University of Wisconsin. School of Medicine and Public Health) ; Rodas, Gil (Medical Services F.C. Barcelona)
The aim of this work was to study semimembranosus musculotendinous injuries (SMMTI) and return to play (RTP). The hypothesis is that some related anatomic variables of the SM could contribute to the prognosis of RTP. [...]
2017 - 10.1055/s-0043-111587
Sports Medicine International Open, Vol. 1, Issue 3 (May 2017) , p. E94-E100  
5.
36 p, 3.1 MB From exome analysis in idiopathic azoospermia to the identification of a high-risk subgroup for occult Fanconi anemia / Krausz, Csilla (Institut d'Investigació Biomèdica Sant Pau) ; Riera-Escamilla, Antoni (Institut d'Investigació Biomèdica Sant Pau) ; Chianese, Chiara (Institut d'Investigació Biomèdica Sant Pau) ; Moreno-Mendoza, Daniel (Institut d'Investigació Biomèdica Sant Pau) ; Ars Criach, Elisabet (Institut d'Investigació Biomèdica Sant Pau) ; Rajmil, Osvaldo (Institut d'Investigació Biomèdica Sant Pau) ; Pujol i Calvet, M. Roser (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Bogliolo, Massimo (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Blanco, Ignacio (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Rodríguez, Inés (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Badell Serra, Isabel (Universitat Autònoma de Barcelona. Departament de Pediatria, Obstetrícia i Ginecologia i de Medicina Preventiva i Salut Pública) ; Ruiz-Castañé, Eduard (Institut d'Investigació Biomèdica Sant Pau) ; Surrallés i Calonge, Jordi (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Purpose: in about 10% of patients affected by Fanconi anemia (FA) the diagnosis is delayed until adulthood, and the presenting symptom in these "occult" FA cases is often a solid cancer and cancer treatment-related toxicity. [...]
2019 - 10.1038/s41436-018-0037-1
Genetics in Medicine, Vol. 21, issue 1 (Jan. 2019) , p. 189-194  
6.
10 p, 1.0 MB Relative contribution of type 1 and type 2 diabetes loci to the genetic etiology of adult-onset, non-insulin-requiring autoimmune diabetes / Mishra, Rajashree (Division of Human Genetics. The Children's Hospital of Philadelphia) ; Chesi, Alessandra (Division of Human Genetics. The Children's Hospital of Philadelphia) ; Cousminer, Diana L. (Department of Genetics, Perelman School of Medicine, University of Pennsylvania) ; Hawa, Mohammad I. (Department of Immunobiology, Barts and the London School of Medicine and Dentistry, Queen Mary University of London) ; Bradfield, Jonathan P. (Center for Applied Genomics, The Children's Hospital of Philadelphia) ; Hodge, Kenyaita M. (Division of Human Genetics. The Children's Hospital of Philadelphia) ; Guy, Vanessa C. (Division of Human Genetics. The Children's Hospital of Philadelphia) ; Hakonarson, Hakon (Division of Human Genetics. The Children's Hospital of Philadelphia) ; Mauricio, Dídac (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Schloot, Nanette C. (German Diabetes Center, Düsseldorf) ; Yderstræde, Knud B. (Odense University Hospital) ; Voight, Benjamin F. (Department of Genetics, Perelman School of Medicine, University of Pennsylvania) ; Schwartz, Stanley (Main Line Health System, Wynnewood, PA, USA.) ; Boehm, Bernhard O. (Department of Internal Medicine I. Ulm University Medical Centre) ; Leslie, Richard David (Department of Immunobiology. Barts and the London School of Medicine and Dentistry, Queen Mary University of London) ; Grant, Struan F. A. (Division of Human Genetics. The Children's Hospital of Philadelphia) ;
Background: In adulthood, autoimmune diabetes can present as non-insulin-requiring diabetes, termed as 'latent autoimmune diabetes in adults' (LADA). In this study, we investigated established type 1 diabetes (T1D) and type 2 diabetes (T2D) genetic loci in a large cohort of LADA cases to assess where LADA is situated relative to these two well-characterized, classic forms of diabetes. [...]
2017
BMC Medicine, Vol. 15 Núm. 88 (2017) , p. 1-10  
7.
12 p, 3.6 MB Electromechanical Conditioning of Adult Progenitor Cells Improves Recovery of Cardiac Function After Myocardial Infarction / Lluciá Valldeperas, Aida (Institut Germans Trias i Pujol) ; Soler Botija, Carolina (Institut Germans Trias i Pujol) ; Gálvez Montón, Carolina (Institut Germans Trias i Pujol) ; Roura, Santiago (Institut Germans Trias i Pujol) ; Prat Vidal, Cristina (Institut Germans Trias i Pujol) ; Perea Gil, Isaac (Institut Germans Trias i Pujol) ; Sanchez, Benjamin (Universitat Politècnica de Catalunya. Departament d'Enginyeria Electrònica) ; Bragos, Ramón (Universitat Politècnica de Catalunya. Departament d'Enginyeria Electrònica) ; Vunjak-Novakovic, Gordana (Columbia University. Biomedical Engineering and Medicine) ; Bayes Genis, Antoni (Universitat Autònoma de Barcelona. Departament de Medicina)
Cardiac cells are subjected to mechanical and electrical forces, which regulate gene expression and cellular function. Therefore, in vitro electromechanical stimuli could benefit further integration of therapeutic cells into the myocardium. [...]
2017 - 10.5966/sctm.2016-0079
Stem cells translational medicine, Vol. 6 (2017) , p. 970-981  
8.
13 p, 1.6 MB Delivery is key: lessons learnt from developing splice-switching antisense therapies / Godfrey, Caroline (University of Oxford. Department of Physiology, Anatomy and Genetics) ; Desviat, Lourdes R (Centro de Biología Molecular Severo Ochoa UAM-CSIC) ; Smedsrød, Bård (University of TromsØ. Department of Medical Biology) ; Piétri-Rouxel, France (Institut de Myologie, Paris) ; Denti, Michela A (Università di Trento. Centre for Integrative Biology) ; Disterer, Petra (University College London. Centre for Amyloidosis and Acute Phase Proteins) ; Lorain, Stéphanie (Institut de Myologie, Paris) ; Nogales Gadea, Gisela (Institut Germans Trias i Pujol. Grup d'Investigació en Malalties Neuromuscular i Neuropediàtriques) ; Sardone, Valentina (University College London) ; Anwar, Rayan (Drug Discovery Informatics Lap, Qasemi-Research Center, Al-Qasemi Academic College) ; EL Andaloussi, Samir (Karolinska Institute. Department of Laboratory Medicine) ; Lehto, Taavi (University of Tartu. Institute of Technology) ; Khoo, Bernard (University College London. Centre for Neuroendocrinology) ; Brolin, Camilla (University of Copenhagen. Department of Cellular and Molecular Medicine) ; van Roon-Mom, Willeke MC (Leiden University Medical Center. DEpartment of Human Genetics) ; Goyenvalle, Aurélie (Université Versailles Saint Quentin) ; Aartsma-Rus, Annemieke (Leiden University Medical Center. Department of Human Genetics) ; Arechavala-Gomeza, Virginia (Neuromuscular Disorders Group. BioCruces Health Research Insitute, Bizkaia) ; Universitat Autònoma de Barcelona
The use of splice-switching antisense therapy is highly promising, with a wealth of pre-clinical data and numerous clinical trials ongoing. Nevertheless, its potential to treat a variety of disorders has yet to be realized. [...]
2017 - 10.15252/emmm.201607199
EMBO Molecular Medicine, Vol. 9 Núm. 5 (2017) , p. 545-557  
9.
9 p, 3.9 MB Noninvasive Assessment of an Engineered Bioactive Graft in Myocardial Infarction: Impact on Cardiac Function and Scar Healing / Gálvez Montón, Carolina (Institut Germans Trias i Pujol. ICREC) ; Bragós, Ramón (Universitat Politècnica de Catalunya. Departament d'Enginyeria Electrònica) ; Soler Botija, Carolina (Institut Germans Trias i Pujol. ICREC) ; Díaz Güemes, Idoia (Centro de Cirugía de Mínima Invasión Jesús Usón) ; Prat Vidal, Cristina (Institut Germans Trias i Pujol. ICREC) ; Crisóstomo, Verónica (Centro de Cirugía de Mínima Invasión Jesús Usón) ; Sánchez Margallo, Francisco M. (Centro de Cirugía de Mínima Invasión Jesús Usón) ; Llucià Vallperas, Aida (Institut Germans Trias i Pujol. ICREC) ; Bogónez Franco, Francisco Carlos (Universitat Politècnica de Catalunya. Departament d'Enginyeria Electrònica) ; Perea Gil, Isaac (Institut Germans Trias i Pujol. ICREC) ; Roura, Santiago (Institut Germans Trias i Pujol. ICREC) ; Bayes Genis, Antoni (Universitat Autònoma de Barcelona. Departament de Medicina)
Cardiac tissue engineering, which combines cells and biomaterials, is promising for limiting the sequelae of myocardial infarction (MI). We assessed myocardial function and scar evolution after implanting an engineered bioactive impedance graft (EBIG) in a swine MI model. [...]
2017
Stems cells translational medicine, Vol. 6 (2017) , p. 647-655  
10.
23 p, 409.2 KB Detection of parathyroid hormone-like hormone in cancer cell cultures by gold nanoparticle-based lateral flow immunoassays / Chamorro García, Alejandro (Institut Català de Nanociència i Nanotecnologia) ; De la Escosura Muñiz, Alfredo (Institut Català de Nanociència i Nanotecnologia) ; Espinoza Castañeda, Marisol (Institut Català de Nanociència i Nanotecnologia) ; Rodríguez-Hernández, Carlos J. (Hospital Universitari Sant Joan de Déu) ; De Torres, Carmen (Hospital Universitari Sant Joan de Déu.) ; Merkoçi, Arben (Institut Català de Nanociència i Nanotecnologia)
Parathyroid hormone-like hormone (PTHLH) exerts relevant roles in progression and dissemination of several tumors. However, factors influencing its production and secretion have not been fully characterized. [...]
2016 - 10.1016/j.nano.2015.09.012
Nanomedicine: Nanotechnology, Biology, and Medicine, Vol. 12, Issue 1 (January 2016) , p. 53-61  

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