Dipòsit Digital de Documents de la UAB 43 registres trobats  1 - 10següentfinal  anar al registre: La cerca s'ha fet en 0.01 segons. 
1.
13 p, 1.4 MB An improved secretion signal enhances the secretion of model proteins from Pichia pastoris / Barrero, Juan J. (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental) ; Casler, Jason C. (University of Chicago. Department of Molecular Genetics and Cell Biology) ; Valero Barranco, Francisco (Universitat Autònoma de Barcelona. Departament d’Enginyeria Quimica, Biològica i Ambiental) ; Ferrer i Alegre, Pau (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental) ; Glick, Benjamin S. (University of Chicago. Department of Molecular Genetics and Cell Biology)
Background: proteins can be secreted from a host organism with the aid of N-terminal secretion signals. The budding yeast Pichia pastoris (Komagataella sp. ) is widely employed to secrete proteins of academic and industrial interest. [...]
2018 - 10.1186/s12934-018-1009-5
Microbial cell factories, Vol. 17 (2018) , art. 161  
2.
13 p, 1.7 MB Metabolic flux analysis and the NAD(P)H/NAD(P) + ratios in chemostat cultures of Azotobacter vinelandii / García, Andres (Universidad Autónoma de México. Instituto de Biotecnologia) ; Ferrer i Alegre, Pau (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental) ; Albiol i Sala, Joan (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental) ; Castillo, Tania (Universidad Autónoma de México. Instituto de Biotecnologia) ; Segura, Daniel (Universidad Nacional Autònoma de México. Instituto de Biotecnologia) ; Peña, Carlos (Universidad Autónoma de México. Instituto de Biotecnologia)
Azotobacter vinelandii is a bacterium that produces alginate and polyhydroxybutyrate (P3HB); however, the role of NAD(P)H/NAD(P) + ratios on the metabolic fluxes through biosynthesis pathways of these biopolymers remains unknown. [...]
2018 - 10.1186/s12934-018-0860-8
Microbial Cell Factories, Vol. 17 (January 2018) , art. 10  
3.
15 p, 2.0 MB The effect of hypoxia on the lipidome of recombinant Pichia pastoris / Adelantado Vallvé, Núria (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental) ; Tarazona, Pablo (Georg-August University. Albrecht-von-Haller-Institute for Plant Sciences) ; Grillitsch, Karlheinz (Austrian Centre of Industrial Biotechnology (ACIB)) ; García Ortega, Xavier (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental) ; Monforte, Sergi (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental) ; Valero Barranco, Francisco (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental) ; Feussner, Ivo (Georg-August University. Albrecht-von-Haller-Institute for Plant Sciences) ; Daum, Günther (Graz University of Technology. Institute of Biochemistry) ; Ferrer Alegre, Pau (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental)
Cultivation of recombinant Pichia pastoris (Komagataella sp. ) under hypoxic conditions has a strong positive effect on specific productivity when the glycolytic GAP promoter is used for recombinant protein expression, mainly due to upregulation of glycolytic conditions. [...]
2017 - 10.1186/s12934-017-0699-4
Microbial Cell Factories, Vol. 16 (May 2017) , art. 86  
4.
7 p, 1.2 MB Recombinant pharmaceuticals from microbial cells : a 2015 update / Sanchez-Garcia, Laura (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Martín, Lucas (Universitat Autònoma de Barcelona. Technology Transfer Office) ; Mangues, Ramon (Institut d'Investigacions Biomèdiques Sant Pau) ; Ferrer-Miralles, Neus (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Vázquez, Esther (CIBER de Bioingeniería, Biomateriales y Nanomedicina (Barcelona)) ; Villaverde, Antonio (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Diabetes, growth or clotting disorders are among the spectrum of human diseases related to protein absence or malfunction. Since these pathologies cannot be yet regularly treated by gene therapy, the administration of functional proteins produced ex vivo is required. [...]
2016 - 10.1186/s12934-016-0437-3
Microbial Cell Factories, Vol. 15, Issue 33 (February 2016)  
5.
1 p, 682.3 KB Erratum to : Detoxifying Escherichia coli for endotoxin-free production of recombinant proteins / Mamat, Uwe (Leibniz-Center for Medicine and Biosciences. Division of Structural Biochemistry) ; Wilke, Kathleen (Leibniz-Center for Medicine and Biosciences. Division of Structural Biochemistry) ; Bramhill, David (Bramhill Biological Consulting. East Moonstone Drive) ; Schromm, Andra Beate (Leibniz-Center for Medicine and Biosciences. Division of Structural Biochemistry) ; Lindner, Buko (Leibniz-Center for Medicine and Biosciences. Division of Structural Biochemistry) ; Kohl, Thomas Andreas (Leibniz-Center for Medicine and Biosciences. Division of Structural Biochemistry) ; Corchero, José Luis (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Villaverde Corrales, Antonio (CIBER de Bioingeniería, Biomateriales y Nanomedicina (Barcelona)) ; Schaffer, Lana (The Scripps Research Institute. NGS and Microarray Core Facility) ; Head, Steven Robert (The Scripps Research Institute. NGS and Microarray Core Facility) ; Souvignier, Chad (Research Corporation Technologies (Tucson)) ; Meredith, Timothy Charles (Pennsylvania State University. Department of Biochemistry and Molecular Biology) ; Woodard, Ronald Wesley (University of Michigan. Department of Medicinal Chemistry)
2015 - 10.1186/s12934-015-0265-x
Microbial cell factories, Vol. 14, Issue 57 (2015)  
6.
13 p, 1.5 MB Use of chemostat cultures mimicking different phases of wine fermentations as a tool for quantitative physiological analysis / Vázquez Lima, Felícitas (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química) ; Silva, Paulina (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química) ; Barreiro Vázquez, Antonio (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química) ; Martínez Moreno, Rubén (Universidad de La Rioja. Instituto de Ciencias de la Vid y del Vino) ; Morales, Pilar (Universidad de La Rioja. Instituto de Ciencias de la Vid y del Vino) ; Quirós, Manuel (Universidad de La Rioja. Instituto de Ciencias de la Vid y del Vino) ; González, Ramón (Universidad de La Rioja. Instituto de Ciencias de la Vid y del Vino) ; Albiol i Sala, Joan (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química) ; Ferrer i Alegre, Pau (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química)
Saccharomyces cerevisiae is the most relevant yeast species conducting the alcoholic fermentation that takes place during winemaking. Although the physiology of this model organism has been extensively studied, systematic quantitative physiology studies of this yeast under winemaking conditions are still scarce, thus limiting the understanding of fermentative metabolism of wine yeast strains and the systematic description, modelling and prediction of fermentation processes. [...]
2014 - 10.1186/1475-2859-13-85
Microbial Cell Factories, Vol. 13 (June 2014) , art. 85  
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5 p, 470.7 KB Packaging protein drugs as bacterial inclusion bodies for therapeutic applications / Villaverde Corrales, Antonio (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; García Fruitós, Elena (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Rinas, Ursula (Helmholtz-Zentrum für Infektionsforschung) ; Seras Franzoso, Joaquin (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Kosoy, Ana (Janus Development SL) ; Corchero Nieto, José Luis (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Vázquez, Esther (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Institut de Biotecnologia i de Biomedicina
A growing number of insights on the biology of bacterial inclusion bodies (IBs) have revealed intriguing utilities of these protein particles. Since they combine mechanical stability and protein functionality, IBs have been already exploited in biocatalysis and explored for bottom-up topographical modification in tissue engineering. [...]
2012 - 10.1186/1475-2859-11-76
Microbial cell factories, Vol. 11 (June 2012) , art. 76  
8.
5 p, 243.9 KB Biological activities of histidine-rich peptides; merging biotechnology and nanomedicine / Ferrer Miralles, Neus (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Corchero Nieto, José Luis (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Kumar, Pradeep (CSIR-Institute of Genomics and Integrative Biology) ; Cedano Rodríguez, Juan Antonio (Universidad de la República (Uruguay).) ; Gupta, Kailash C (CSIR-Indian Institute of Toxicology Research) ; Villaverde Corrales, Antonio (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Vázquez Gómez, Esther (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Histidine-rich peptides are commonly used in recombinant protein production as purification tags, allowing the one-step affinity separation of the His-tagged proteins from the extracellular media or cell extracts. [...]
2011 - 10.1186/1475-2859-10-101
Microbial cell factories, Vol. 10 (2011) , art. 101  
9.
7 p, 370.3 KB Co-production of GroELS discriminates between intrinsic and thermally-induced recombinant protein aggregation during substrate quality control / Platas, Gemma (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Rodríguez-Carmona, Escarlata (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; García Fruitós, Elena (CIBER de Bioingeniería, Biomateriales y Nanomedicina) ; Cano Garrido, Olivia (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Villaverde Corrales, Antonio (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Universitat Autònoma de Barcelona. Departament de Genètica i Microbiologia
The effects and effectiveness of the chaperone pair GroELS on the yield and quality of recombinant polypeptides produced in Escherichia coli are matter of controversy, as the reported activities of this complex are not always consistent and eventually indicate undesired side effects. [...]
2011 - 10.1186/1475-2859-10-79
Microbial cell factories, Vol. 10 (October 2011) , art. 79  
10.
6 p, 314.6 KB Post-production protein stability : trouble beyond the cell factory / Vázquez, Esther (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Corchero Nieto, José Luis (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Villaverde Corrales, Antonio (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Being protein function a conformation-dependent issue, avoiding aggregation during production is a major challenge in biotechnological processes, what is often successfully addressed by convenient upstream, midstream or downstream approaches. [...]
2011 - 10.1186/1475-2859-10-60
Microbial cell factories, Vol. 10 (2011) , art. 60  

Dipòsit Digital de Documents de la UAB : 43 registres trobats   1 - 10següentfinal  anar al registre:
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