UAB Digital Repository of Documents 26 records found  1 - 10nextend  jump to record: Search took 0.00 seconds. 
1.
23 p, 5.4 MB Design, synthesis, biological evaluation and in silico study of benzyloxybenzaldehyde derivatives as selective aldh1a3 inhibitors / Ibrahim, Ali I.M. (Al-Zaytoonah University of Jordan. Faculty of Pharmacy) ; Ikhmais, Balqis (Al-Zaytoonah University of Jordan. Faculty of Pharmacy) ; Batlle, Elisabet (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Abuharb, Waed K. (Al-Zaytoonah University of Jordan. Faculty of Pharmacy) ; Jha, Vibhu (University of Pisa. Department of Pharmacy) ; Jaradat, Khaled T. (American University of the Middle East. College of Engineering and Technology) ; Jiménez, Rafael (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Pequerul, Raquel (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Parés, Xavier (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Farrés, Jaume (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Pors, Klaus (University of Bradford. Faculty of Life Sciences)
Aldehyde dehydrogenase 1A3 (ALDH1A3) has recently gained attention from researchers in the cancer field. Several studies have reported ALDH1A3 overexpression in different cancer types, which has been found to correlate with poor treatment recovery. [...]
2021 - 10.3390/molecules26195770
Molecules, Vol. 26 Núm. 19 (september 2021) , p. 5770  
2.
12 p, 1.9 MB Selenite downregulates STAT3 expression and provokes lymphocytosis in the liver of chronically exposed Syrian golden hamsters / Camacho Moll, Maria Elena (Centro de Investigación Biomédica del Noreste (Nuevo León, Mèxic)) ; Sampayo-Reyes, Adriana (Universidad Autónoma de Nuevo León. Facultad de Ciencias Biológicas) ; Castorena-Torres, Fabiola (Tecnológico de Monterrey. Escuela de Medicina) ; Lozano-Garza, Gerardo (Centro de Investigación Biomédica del Noreste (Nuevo León, Mèxic)) ; Alarcón-Galván, Gabriela (Universidad de Monterrey. Departamento de Ciencias Básicas) ; Hernández Bonilla, Alba (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Marcos Dauder, Ricardo (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Alcocer-González, Juan (Universidad Autónoma de Nuevo León. Facultad de Ciencias Biológicas) ; Tamez-Guerra, Reyes (Universidad Autónoma de Nuevo León. Facultad de Ciencias Biológicas) ; León, Mario Bermúdez de (Centro de Investigación Biomédica del Noreste (Nuevo León, Mèxic))
Arsenic is considered a worldwide pollutant that can be present in drinking water. Arsenic exposure is associated with various diseases, including cancer. Antioxidants as selenite and α-tocopherol-succinate have been shown to modulate arsenic toxic effects. [...]
2021 - 10.3390/molecules26185614
Molecules, Vol. 26, issue 18 (Sep. 2021) , art. 5614  
3.
13 p, 1.1 MB Genetic diversity and association of EST-SSR and SCoT markers with rust traits in Orchardgrass (Dactylis glomerata L.) / Yan, Haidong (Sichuan Agricultural University. Department of Grassland Science (China)) ; Zhang, Yu (Centre de Recerca en Agrigenòmica) ; Zeng, Bing (Southwest University. Department of Animal Science (China)) ; Yin, Guohua (University of Arkansas. Department of Crop, Soil, and Environmental Sciences (USA)) ; Zhang, Xinquan (Sichuan Agricultural University. Department of Grassland Science (China)) ; Ji, Yang (Sichuan Animal Science Academy. Department of Grassland Science (China)) ; Huang, Linkai (Sichuan Agricultural University. Department of Grassland Science (China)) ; Jiang, Xiaomei (Sichuan Agricultural University. Department of Grassland Science (China)) ; Liu, Xinchun (Sichuan Agricultural University. Agricultural College (China)) ; Peng, Yan (Sichuan Agricultural University. Department of Grassland Science (China)) ; Ma, Xiao (Sichuan Agricultural University. Department of Grassland Science (China)) ; Yan, Yanhong (Sichuan Agricultural University. Department of Grassland Science (China))
Orchardgrass (Dactylis glomerata L. ), is a well-known perennial forage species; however, rust diseases have caused a noticeable reduction in the quality and production of orchardgrass. In this study, genetic diversity was assessed and the marker-trait associations for rust were examined using 18 EST-SSR and 21 SCoT markers in 75 orchardgrass accessions. [...]
2016 - 10.3390/molecules21010066
Molecules, Vol. 21, Issue 1 (January 2016) , art. 66  
4.
23 p, 5.6 MB Construction of Zn(II) Linear Trinuclear Secondary Building Units from A Coordination Polymer Based on α-Acetamidocinnamic Acid and 4-Phenylpyridine / Ejarque, Daniel (Universitat Autònoma de Barcelona. Departament de Química) ; Calvet, Teresa (Universitat de Barcelona. Departament de Mineralogia, Petrologia i Geologia Aplicada) ; Font-Bardia, Mercè (Universitat de Barcelona. Centres Científics i Tecnològics) ; Pons Picart, Josefina (Universitat Autònoma de Barcelona. Departament de Química)
The synthesis and characterization of one coordination polymer and two trinuclear complexes are presented. The coordination polymer [Zn2(µ-O,O'-ACA)2(ACA)2(4-Phpy)2]n (1) has been obtained by the reaction between Zn(OAc)2·2H2O, α-acetamidocinnamic acid (HACA), and 4-phenylpyridine (4-Phpy) using EtOH as solvent. [...]
2020 - 10.3390/molecules25163615
Molecules, Vol. 25, Núm. 16 (August 2020) , art. 3615  
5.
16 p, 1.9 MB Design of Targeted Nanostructured Coordination Polymers (NCPs) for Cancer Therapy / Novio Vázquez, Fernando (Universitat Autònoma de Barcelona. Departament de Química)
Conventional cancer chemotherapy presents notable drug side effects due to non-selective action of the chemotherapeutics to normal cells. Nanoparticles decorated with receptor-specific ligands on the surface have shown an important role in improving site-selective binding, retention, and drug delivery to the cancer cells. [...]
2020 - 10.3390/molecules25153449
Molecules, Vol. 25, Núm. 15 (August 2020) , art. 3449  
6.
24 p, 4.9 MB Asymmetric Preparation of α-Quaternary Fluorinated β-keto Esters. Review / Granados Toda, Albert (Universitat Autònoma de Barcelona. Departament de Química) ; Vallribera Massó, Adelina (Universitat Autònoma de Barcelona. Departament de Química)
In this review, recent advances over the past decade in the preparation of fluorinated stereogenic quaternary centers on β-keto esters compounds are analyzed. Since the incorporation of fluorine and fluorinated groups is of special interest in pharmaceutical chemistry, a range of metal-catalyzed and organocatalyzed methods have been developed. [...]
2020 - 10.3390/molecules25143264
Molecules, Vol. 25, Núm. 14 (July 2020) , art. 3264  
7.
12 p, 620.4 KB 31P-NMR metabolomics revealed species-specific use of phosphorous in trees of a French Guiana rainforest / Gargallo-Garriga, Albert (Centre de Recerca Ecològica i d'Aplicacions Forestals) ; Sardans i Galobart, Jordi (Centre de Recerca Ecològica i d'Aplicacions Forestals) ; Llusià Benet, Joan (Centre de Recerca Ecològica i d'Aplicacions Forestals) ; Peguero, Guille (Centre de Recerca Ecològica i d'Aplicacions Forestals) ; Asensio, Dolores (Centre de Recerca Ecològica i d'Aplicacions Forestals) ; Ogaya Inurrigarro, Romà (Centre de Recerca Ecològica i d'Aplicacions Forestals) ; Urbina Barreto, Ifigenia (Centre de Recerca Ecològica i d'Aplicacions Forestals) ; Van Langenhove, Leandro (University of Antwerp. Department of Biology) ; Verryckt, Lore (University of Antwerp. Department of Biology) ; Courtois, Elodie A. (University of Antwerp. Department of Biology) ; Stahl, Clément (INRA. EcoFoG) ; Grau Fernández, Oriol (Centre de Recerca Ecològica i d'Aplicacions Forestals) ; Urban, Otmar (Global Change Research Institute CAS) ; Janssens, Ivan (University of Antwerp. Department of Biology) ; Nolis, Pau (Universitat Autònoma de Barcelona. Servei de Ressonància Magnètica Nuclear) ; Pérez-Trujillo, Míriam (Universitat Autònoma de Barcelona. Servei de Ressonància Magnètica Nuclear) ; Parella Coll, Teodor (Universitat Autònoma de Barcelona. Servei de Ressonància Magnètica Nuclear) ; Peñuelas, Josep (Centre de Recerca Ecològica i d'Aplicacions Forestals)
Productivity of tropical lowland moist forests is often limited by availability and functional allocation of phosphorus (P) that drives competition among tree species and becomes a key factor in determining forestall community diversity. [...]
2020 - 10.3390/molecules25173960
Molecules, Vol. 25, issue 17 (2020) , art. 3960  
8.
19 p, 352.1 KB Representation Learning for Class C G Protein-Coupled Receptors Classification / Cruz-Barbosa, Raúl (Technological University of the Mixteca Region. Computer Science Institute) ; Ramos-Pérez, Erik-German (Technological University of the Mixteca Region. Computer Science Institute) ; Giraldo, Jesús (Universitat Autònoma de Barcelona. Institut de Neurociències)
G protein-coupled receptors (GPCRs) are integral cell membrane proteins of relevance for pharmacology. The complete tertiary structure including both extracellular and transmembrane domains has not been determined for any member of class C GPCRs. [...]
2018 - 10.3390/molecules23030690
Molecules, Vol. 23 Núm.3 (march 2018)  
9.
12 p, 398.4 KB Colistin Use in Patients with Chronic Kidney Disease : Are We Underdosing Patients? / Sorlí, Luisa (Hospital del Mar (Barcelona, Catalunya)) ; Luque, Sonia (Hospital del Mar (Barcelona, Catalunya)) ; Li, Jian (Monash University) ; Rodríguez, Eva (Institut Hospital del Mar d'Investigacions Mèdiques) ; Campillo, Nuria (Institut Hospital del Mar d'Investigacions Mèdiques) ; Fernández Sala, Xènia (Institut Hospital del Mar d'Investigacions Mèdiques) ; Soldado, Jade (Institut Hospital del Mar d'Investigacions Mèdiques) ; Domingo, Ignacio (Hospital del Mar (Barcelona, Catalunya)) ; Montero, Milagro (Institut Hospital del Mar d'Investigacions Mèdiques) ; Grau, Santiago (Hospital del Mar (Barcelona, Catalunya)) ; Horcajada, Juan Pablo. (Hospital del Mar (Barcelona, Catalunya)) ; Universitat Autònoma de Barcelona
Colistin is administered as its inactive prodrug colistimethate (CMS). Selection of an individualized CMS dose for each patient is difficult due to its narrow therapeutic window, especially in patients with chronic kidney disease (CKD). [...]
2019 - 10.3390/molecules24030530
Molecules, Vol. 24 (february 2019)  
10.
10 p, 2.0 MB Catalytic asymmetric fluorination of Alkyl 1-indanone-2-carboxylates Ruled by Pybox-Eu(III) Combination / Granados Toda, Albert (Universitat Autònoma de Barcelona. Departament de Química) ; Sarró, Pau (Universitat Autònoma de Barcelona. Departament de Química) ; Vallribera Massó, Adelina (Universitat Autònoma de Barcelona. Departament de Química)
A highly enantioselective catalytic method for the synthesis of quaternary α-fluoro derivatives of 3-oxo esters is described. The reaction uses europium (III) triflate and commercially available chiral pybox-type C2-symmetric ligand. [...]
2019 - 10.3390/molecules24061141
Molecules, Vol. 24, Núm. 6 (March 2019) , art. 1141  

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