Depósito Digital de Documentos de la UAB Encontrados 101 registros  1 - 10siguientefinal  ir al registro: La búsqueda tardó 0.00 segundos. 
1.
9 p, 883.5 KB Reversal of the seasonality of temperature-attributable mortality from respiratory diseases in Spain / Achebak, Hicham (Centre d'Estudis Demogràfics) ; Devolder, Daniel (Universitat Autònoma de Barcelona. Centre d'Estudis Demogràfics) ; Ingole, Vijendra (Barcelona Institute for Global Health (ISGlobal)) ; Ballester, Joan (Barcelona Institute for Global Health (ISGlobal))
A growing number of epidemiological studies have recently assessed temporal variations in vulnerability and/or mortality attributable to hot and cold temperatures. However, the eventual changes in the seasonal distribution of temperature-attributable mortality remain unexplored. [...]
2020 - 10.1038/s41467-020-16273-x
Nature communications, Vol. 11 Núm. 2457 (2020)  
2.
12 p, 3.6 MB DNA methylation loss promotes immune evasion of tumours with high mutation and copy number load / Jung, H. (Department of Bio and Brain Engineering. KAIST) ; Kim, H.S. (Division of Hematology/Oncology. Department of Medicine. Samsung Medical Center. Sungkyunkwan University School of Medicine) ; Kim, J.Y. (Department of Bio and Brain Engineering. KAIST) ; Sun, J.M. (Division of Hematology/Oncology. Department of Medicine. Samsung Medical Center. Sungkyunkwan University School of Medicine) ; Ahn, J.S. (Division of Hematology/Oncology. Department of Medicine. Samsung Medical Center. Sungkyunkwan University School of Medicine) ; Ahn, M.J. (Division of Hematology/Oncology. Department of Medicine. Samsung Medical Center. Sungkyunkwan University School of Medicine) ; Park, K. (Division of Hematology/Oncology. Department of Medicine. Samsung Medical Center. Sungkyunkwan University School of Medicine) ; Esteller, M. (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Lee, S.H. (Department of Health Sciences and Technology. Samsung Advanced Institute of Health Science and Technology. Sungkyunkwan University) ; Choi, J.K. (Penta Medix Co.. Ltd.) ; Universitat Autònoma de Barcelona
Mitotic cell division increases tumour mutation burden and copy number load, predictive markers of the clinical benefit of immunotherapy. Cell division correlates also with genomic demethylation involving methylation loss in late-replicating partial methylation domains. [...]
2019 - 10.1038/s41467-019-12159-9
Nature communications, Vol. 10 Núm. 1 (january 2019) , p. 4278  
3.
18 p, 2.5 MB The transcribed pseudogene RPSAP52 enhances the oncofetal HMGA2-IGF2BP2-RAS axis through LIN28B-dependent and independent let-7 inhibition / Oliveira-Mateos, C. (Institut d'Investigació Biomèdica de Bellvitge) ; Sánchez-Castillo, A. (Centro de Investigación Biomédica en Red de Cáncer (CIBERONC). Carlos III Institute of Health (ISCIII)) ; Soler, Marta (Institut d'Investigació Biomèdica de Bellvitge) ; Obiols-Guardia, A. (Institut d'Investigació Biomèdica de Bellvitge) ; Piñeyro, David (Institut d'Investigació Biomèdica de Bellvitge) ; Boque-Sastre, R. (Cardiff School of Biosciences. Cardiff University) ; Calleja-Cervantes, M.E. (Institut d'Investigació Biomèdica de Bellvitge) ; Castro de Moura, M. (Institut d'Investigació Biomèdica de Bellvitge) ; Martínez Cardús, Anna (Institut d'Investigació Biomèdica de Bellvitge) ; Rubio, T. (Institut d'Investigació Biomèdica de Bellvitge) ; Pelletier, Joffrey (Institut d'Investigació Biomèdica de Bellvitge) ; Martínez-Iniesta, M. (Program Against Cancer Therapeutic Resistance (ProCURE). ICO. IDIBELL. L'Hospitalet de Llobregat) ; Herrero-Martín, D. (Institut d'Investigació Biomèdica de Bellvitge) ; Tirado, O.M. (Institut d'Investigació Biomèdica de Bellvitge) ; Gentilella, A. (Universitat de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Villanueva, A. (Program Against Cancer Therapeutic Resistance (ProCURE). ICO. IDIBELL. L'Hospitalet de Llobregat) ; Esteller, M. (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Farré, L. (Laboratory of Experimental Pathology (LAPEX). Gonçalo Moniz Research Center. Oswaldo Cruz Foundation (CPQGM/FIOCRUZ)) ; Guil, Sonia (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Universitat Autònoma de Barcelona
One largely unknown question in cell biology is the discrimination between inconsequential and functional transcriptional events with relevant regulatory functions. Here, we find that the oncofetal HMGA2 gene is aberrantly reexpressed in many tumor types together with its antisense transcribed pseudogene RPSAP52. [...]
2019 - 10.1038/s41467-019-11910-6
Nature communications, Vol. 10 Núm. 1 (january 2019) , p. 3979  
4.
11 p, 3.4 MB Identification of key sequence features required for microRNA biogenesis in plants / Rojas, Arantxa M.L. (Instituto de Biología Molecular y Celular de Rosario) ; Drusin, Salvador I. (Instituto de Biología Molecular y Celular de Rosario) ; Chorostecki, Uciel Pablo (Instituto de Investigación en Biomedicina. Instituto de Ciencia y Tecnología de Barcelona) ; Mateos, Julieta Lisa (Instituto de Fisiología, Biología Molecular y Neurociencias) ; Moro, Belen (Centre de Recerca en Agrigenòmica) ; Bologna, Nicolás (Centre de Recerca en Agrigenòmica) ; Bresso, Edgardo G. (Instituto de Biología Molecular y Celular de Rosario) ; Schapire, Arnaldo (Instituto de Biología Molecular y Celular de Rosario) ; Rasia, Rodolfo (Instituto de Biología Molecular y Celular de Rosario) ; Moreno, Diego M. (Universidad Nacional de Rosario. Departamento de Química-Física) ; Palatnik, Javier (Instituto de Biología Molecular y Celular de Rosario)
MicroRNAs (miRNAs) are endogenous small RNAs of ∼21 nt that regulate multiple biological pathways in multicellular organisms. They derive from longer transcripts that harbor an imperfect stem-loop structure. [...]
2020 - 10.1038/s41467-020-19129-6
Nature communications, Vol. 11 (October 2020) , art. 5320  
5.
15 p, 4.1 MB Donkey genomes provide new insights into domestication and selection for coat color / Wang, Changfa (Liaocheng University. Liaocheng Research Institute of Donkey High-Efficiency Breeding and Ecological Feeding) ; Li, Haijing (National Engineering Research Center for Gelatin-based Traditional Chinese Medicine) ; Guo, Yu (BGI-Shenzhen) ; Huang, Jinming (Shandong Academy of Agricultural Sciences. Dairy Cattle Research Center) ; Sun, Yan (Shandong Academy of Agricultural Sciences. Dairy Cattle Research Center) ; Min, Jiumeng (BGI-Shenzhen) ; Wang, Jinpeng (Shandong Academy of Agricultural Sciences. Dairy Cattle Research Center) ; Fang, Xiaodong (BGI-Shenzhen) ; Zhao, Zicheng (City University of Hong Kong. Department of Computer Science) ; Wang, Shuai (City University of Hong Kong. Department of Computer Science) ; Zhang, Yanlin (City University of Hong Kong. Department of Computer Science) ; Liu, Qingfeng (BGI-Shenzhen) ; Jiang, Qiang (Shandong Academy of Agricultural Sciences. Dairy Cattle Research Center) ; Wang, Xiuge (Shandong Academy of Agricultural Sciences. Dairy Cattle Research Center) ; Guo, Yijun (BGI-Shenzhen) ; Yang, Chunhong (Shandong Academy of Agricultural Sciences. Dairy Cattle Research Center) ; Wang, Yinchao (National Engineering Research Center for Gelatin-based Traditional Chinese Medicine) ; Tian, Fang (National Engineering Research Center for Gelatin-based Traditional Chinese Medicine) ; Zhuang, Guilong (Shandong Academy of Agricultural Sciences. Dairy Cattle Research Center) ; Fan, Yanna (Shandong Academy of Agricultural Sciences. Dairy Cattle Research Center) ; Gao, Qican (Shandong Academy of Agricultural Sciences. Dairy Cattle Research Center) ; Li, Yuhua (Liaocheng University. Liaocheng Research Institute of Donkey High-Efficiency Breeding and Ecological Feeding) ; Ju, Zhihua (Shandong Academy of Agricultural Sciences. Dairy Cattle Research Center) ; Li, Jianbin (Shandong Academy of Agricultural Sciences. Dairy Cattle Research Center) ; Li, Rongling (Shandong Academy of Agricultural Sciences. Dairy Cattle Research Center) ; Hou, Minghai (Shandong Academy of Agricultural Sciences. Dairy Cattle Research Center) ; Yang, Guiwen (Shandong Normal University. College of Life Science) ; Liu, Guiqin (Liaocheng University. Liaocheng Research Institute of Donkey High-Efficiency Breeding and Ecological Feeding) ; Liu, Wenqiang (Liaocheng University Liaocheng Research Institute of Donkey High-Efficiency Breeding and Ecological Feeding.) ; Guo, Jiao (BGI-Shenzhen) ; Pan, Shanshan (BGI-Shenzhen) ; Fan, Guangyi (BGI-Shenzhen) ; Zhang, Wei (Shandong Academy of Agricultural Sciences. Dairy Cattle Research Center) ; Zhang, Ruitao (Liaocheng University. Liaocheng Research Institute of Donkey High-Efficiency Breeding and Ecological Feeding) ; Yu, Jie (National Engineering Research Center for Gelatin-based Traditional Chinese Medicine) ; Zhang, Xinhao (National Engineering Research Center for Gelatin-based Traditional Chinese Medicine) ; Yin, Qi (BGI-Shenzhen) ; Ji, Chuanliang (National Engineering Research Center for Gelatin-based Traditional Chinese Medicine) ; Jin, Yuanchun (BGI-Shenzhen) ; Yue, Guidong (BGI-Shenzhen) ; Liu, Mei (Nanjing Normal University. Jiangsu Key Laboratory for Molecular and Medical Biotechnology) ; Xu, Jiake (The University of Western Australia . School of Biomedical Sciences) ; Liu, Shimin (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments) ; Jordana i Vidal, Jordi (Universitat Autònoma de Barcelona. Departament de Ciència Animal i dels Aliments) ; Noce, Antonia (Centre de Recerca en Agrigenòmica) ; Amills i Eras, Marcel (Centre de Recerca en Agrigenòmica) ; Wu, Dong-Dong (Chinese Academy of Sciences. Center for Excellence in Animal Evolution and Genetics) ; Li, Shuaicheng (City University of Hong Kong. Department of Computer Science) ; Zhou, Xiangshan (East China University of Science and Technology. State Key Laboratory of Bioreactor Engineering) ; Zhong, Jifeng (Jiangsu Academy of Agricultural Sciences. Institute of Animal Science)
Current knowledge about the evolutionary history of donkeys is still incomplete due to the lack of archeological and whole-genome diversity data. To fill this gap, we have de novo assembled a chromosome-level reference genome of one male Dezhou donkey and analyzed the genomes of 126 domestic donkeys and seven wild asses. [...]
2020 - 10.1038/s41467-020-19813-7
Nature communications, Vol. 11 (December 2020) , art. 6014  
6.
15 p, 2.9 MB MethCORR modelling of methylomes from formalin-fixed paraffin-embedded tissue enables characterization and prognostication of colorectal cancer / Mattesen, T.B. (Department of Molecular Medicine. Aarhus University Hospital) ; Rasmussen, M.H. (Department of Molecular Medicine. Aarhus University Hospital) ; Sandoval, J. (Biomarker and precision medicine Unit. Health Research Institute La Fe (ISSLaFe)) ; Ongen, H. (Genetic Medicine and Development. University of Geneva Medical School-CMU) ; Árnadóttir, S.S. (Department of Molecular Medicine. Aarhus University Hospital) ; Gladov, J. (Department of Molecular Medicine. Aarhus University Hospital) ; Martínez Cardús, Anna (Institut Germans Trias i Pujol) ; Castro de Moura, Manuel (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Madsen, A.H. (Department of Surgery. Hospitalsenheden Vest) ; Laurberg, S. (Colorectal Surgical Unit. Department of Surgery. Aarhus University Hospital) ; Dermitzakis, E.T. (Genetic Medicine and Development. University of Geneva Medical School-CMU) ; Esteller, M. (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Andersen, C.L. (Department of Molecular Medicine. Aarhus University Hospital) ; Bramsen, J.B. (Department of Molecular Medicine. Aarhus University Hospital) ; Universitat Autònoma de Barcelona
Transcriptional characterization and classification has potential to resolve the inter-tumor heterogeneity of colorectal cancer and improve patient management. Yet, robust transcriptional profiling is difficult using formalin-fixed, paraffin-embedded (FFPE) samples, which complicates testing in clinical and archival material. [...]
2020 - 10.1038/s41467-020-16000-6
Nature communications, Vol. 11 Núm. 1 (january 2020) , p. 2025  
7.
14 p, 1.8 MB In vivo CRISPR/Cas9 targeting of fusion oncogenes for selective elimination of cancer cells / Martinez-Lage, M. (Centro Nacional de Investigaciones Oncológicas-CNIO (Madrid, Espanya)) ; Torres, Raul (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Puig-Serra, P. (Centro Nacional de Investigaciones Oncológicas-CNIO (Madrid, Espanya)) ; Moreno-Gaona, P. (Centro Nacional de Investigaciones Oncológicas-CNIO (Madrid, Espanya)) ; Martin, M.C. (Centro Nacional de Investigaciones Oncológicas-CNIO (Madrid, Espanya)) ; Moya, F.J. (Centro Nacional de Investigaciones Oncológicas-CNIO (Madrid, Espanya)) ; Quintana-Bustamante, O. (Universidad Autónoma de Madrid. Instituto de Investigación Sanitaria-Fundación Jiménez Díaz) ; Garcia-Silva, S. (Centro Nacional de Investigaciones Oncológicas-CNIO (Madrid, Espanya)) ; Carcaboso, A.M. (Hospital Sant Joan de Déu (Barcelona, Catalunya)) ; Petazzi, Paolo (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Bueno, Clara (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Mora, J. (Hospital Sant Joan de Déu (Barcelona, Catalunya)) ; Peinado, H. (Centro Nacional de Investigaciones Oncológicas-CNIO (Madrid, Espanya)) ; Segovia, J.C. (Universidad Autónoma de Madrid. Instituto de Investigación Sanitaria-Fundación Jiménez Díaz) ; Menéndez, Pablo (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Rodriguez-Perales, S. (Centro Nacional de Investigaciones Oncológicas-CNIO (Madrid, Espanya)) ; Universitat Autònoma de Barcelona
Fusion oncogenes (FOs) are common in many cancer types and are powerful drivers of tumor development. Because their expression is exclusive to cancer cells and their elimination induces cell apoptosis in FO-driven cancers, FOs are attractive therapeutic targets. [...]
2020 - 10.1038/s41467-020-18875-x
Nature communications, Vol. 11 Núm. 1 (january 2020) , p. 5060  
8.
17 p, 5.7 MB An integrated multi-omics approach identifies the landscape of interferon-α-mediated responses of human pancreatic beta cells / Colli, M.L. (ULB Center for Diabetes Research. Medical Faculty. Université Libre de Bruxelles) ; Ramos-Rodríguez, M. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Nakayasu, E.S. (Biological Sciences Division. Pacific Northwest National Laboratory) ; Alvelos, M.I. (ULB Center for Diabetes Research. Medical Faculty. Université Libre de Bruxelles) ; Lopes, M. (ULB Center for Diabetes Research. Medical Faculty. Université Libre de Bruxelles) ; Hill, J.L.E. (Institute of Biomedical & Clinical Science. University of Exeter Medical School) ; Turatsinze, J.V. (ULB Center for Diabetes Research. Medical Faculty. Université Libre de Bruxelles) ; Coomans de Brachène, A. (ULB Center for Diabetes Research. Medical Faculty. Université Libre de Bruxelles) ; Russell, M.A. (Institute of Biomedical & Clinical Science. University of Exeter Medical School) ; Raurell-Vila, H. (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Castela, A. (ULB Center for Diabetes Research. Medical Faculty. Université Libre de Bruxelles) ; Juan-Mateu, J. (ULB Center for Diabetes Research. Medical Faculty. Université Libre de Bruxelles) ; Webb-Robertson, B.J.M. (Biological Sciences Division. Pacific Northwest National Laboratory) ; Krogvold, L. (Division of Pediatric and Adolescent Medicine. Faculty of Medicine. Oslo University Hospital) ; Dahl-Jorgensen, K. (Division of Pediatric and Adolescent Medicine. Faculty of Medicine. Oslo University Hospital) ; Marselli, L. (Department of Clinical and Experimental Medicine. Islet Cell Laboratory. University of Pisa) ; Marchetti, P. (Department of Clinical and Experimental Medicine. Islet Cell Laboratory. University of Pisa) ; Richardson, S.J. (Institute of Biomedical & Clinical Science. University of Exeter Medical School) ; Morgan, N.G. (Institute of Biomedical & Clinical Science. University of Exeter Medical School) ; Metz, T.O. (Biological Sciences Division. Pacific Northwest National Laboratory) ; Pasquali, Lorenzo (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Eizirik, D.L. (Indiana Biosciences Research Institute) ; Universitat Autònoma de Barcelona
Interferon-α (IFNα), a type I interferon, is expressed in the islets of type 1 diabetic individuals, and its expression and signaling are regulated by T1D genetic risk variants and viral infections associated with T1D. [...]
2020 - 10.1038/s41467-020-16327-0
Nature communications, Vol. 11 Núm. 1 (january 2020) , p. 2584  
9.
6 p, 3.4 MB Blue emission at atomically sharp 1D heterojunctions between graphene and h-BN / Kim, Gwangwoo (Ulsan National Institute of Science and Technology. Department of Chemistry) ; Ma, Kyung Yeol (Ulsan National Institute of Science and Technology. Department of Energy Engineering) ; Park, Minsu (Korea Advanced Institute of Science and Technology. Department of Materials Science and Engineering) ; Kim, Minsu (Ulsan National Institute of Science and Technology. Department of Chemistry) ; Jeon, Jonghyuk (Seoul National University. Department of Chemistry) ; Song, Jinouk (Korea Advanced Institute of Science and Technology. School of Electrical Engineering) ; Barrios Vargas, José Eduardo (Universidad Nacional Autónoma de México. Departamento de Física y Química Teórica) ; Sato, Yuta (National Institute of Advanced Industrial Science and Technology. Nanomaterials Research Institute) ; Lin, Yung-Chang (National Institute of Advanced Industrial Science and Technology. Nanomaterials Research Institute) ; Suenaga, Kazu (National Institute of Advanced Industrial Science and Technology. Nanomaterials Research Institute) ; Roche, Stephan (Institut Català de Nanociència i Nanotecnologia) ; Yoo, Seunghyup (Korea Advanced Institute of Science and Technology. School of Electrical Engineering) ; Sohn, Byeong-Hyeok (Seoul National University. Department of Chemistry) ; Jeon, Seokwoo (Korea Advanced Institute of Science and Technology. Department of Materials Science and Engineering) ; Shin, Hyeon Suk (Ulsan National Institute of Science and Technology. Low Dimensional Carbon Material Center)
Atomically sharp heterojunctions in lateral two-dimensional heterostructures can provide the narrowest one-dimensional functionalities driven by unusual interfacial electronic states. For instance, the highly controlled growth of patchworks of graphene and hexagonal boron nitride (h-BN) would be a potential platform to explore unknown electronic, thermal, spin or optoelectronic property. [...]
2020 - 10.1038/s41467-020-19181-2
Nature communications, Vol. 11 (2020) , art. 5359  
10.
17 p, 7.1 MB Graphene active sensor arrays for long-term and wireless mapping of wide frequency band epicortical brain activity / Garcia Cortadella, Ramon (Institut Català de Nanociència i Nanotecnologia) ; Schwesig, G. (Ludwig-Maximilians Universität München. Bernstein Center for Computational Neuroscience Munich (Germany)) ; Jeschke, C. (Multi Channel Systems GmbH (Germany)) ; Illa, Xavi (Instituto de Microelectrónica de Barcelona) ; Gray, Anna L. (University of Manchester. National Graphene Institute. Nanomedicine Lab (UK)) ; Savage, S. (University of Manchester. National Graphene Institute. Nanomedicine Lab (UK)) ; Stamatidou, E. (University of Manchester. National Graphene Institute. Nanomedicine Lab (UK)) ; Schiessl, I. (University of Manchester. Division of Neuroscience and Experimental Psychology (UK)) ; Masvidal-Codina, E. (Instituto de Microelectrónica de Barcelona) ; Kostarelos, Kostas (Institut Català de Nanociència i Nanotecnologia) ; Guimerà-Brunet, A. (Instituto de Microelectrónica de Barcelona) ; Sirota, Anton (Ludwig-Maximilians Universität München. Bernstein Center for Computational Neuroscience Munich (Germany)) ; Garrido, Jose (Institut Català de Nanociència i Nanotecnologia)
Graphene active sensors have demonstrated promising capabilities for the detection of electrophysiological signals in the brain. Their functional properties, together with their flexibility as well as their expected stability and biocompatibility have raised them as a promising building block for large-scale sensing neural interfaces. [...]
2021 - 10.1038/s41467-020-20546-w
Nature communications, Vol. 12 (January 2021) , art. 211  

Depósito Digital de Documentos de la UAB : Encontrados 101 registros   1 - 10siguientefinal  ir al registro:
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