UAB Digital Repository of Documents 43 records found  1 - 10nextend  jump to record: Search took 0.01 seconds. 
1.
58 p, 970.8 KB RiboTag : Ribosomal tagging strategy to analyze cell type specific mRNA expression in vivo / Sanz Iglesias, Elisenda (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Bean, Jonathan C. (University of Washington. Department of Pharmacology) ; Carey, Daniel P. (University of Washington. Department of Pharmacology) ; Quintana Romero, Albert (Universitat Autònoma de Barcelona. Institut de Neurociències) ; McKnight, G. Stanley (University of Washington. Department of Pharmacology)
Ribosome tagging has become a very useful in vivo approach for analyzing gene expression and mRNA translation in specific cell types that are difficult and time consuming to isolate by conventional methods. [...]
2019 - 10.1002/cpns.77
Current Protocols in Neuroscience, 2019  
2.
25 p, 2.6 MB Mitochondrial Quality Control in Neurodegenerative Diseases : Focus on Parkinson's Disease and Huntington's Disease / Franco-Iborra, Sandra (Vall d'Hebron. Institut de Recerca (VHIR)) ; Vila Bover, Miquel (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Perier, Celine (Vall d'Hebron. Institut de Recerca (VHIR))
In recent years, several important advances have been made in our understanding of the pathways that lead to cell dysfunction and death in Parkinson's disease (PD) and Huntington's disease (HD). Despite distinct clinical and pathological features, these two neurodegenerative diseases share critical processes, such as the presence of misfolded and/or aggregated proteins, oxidative stress, and mitochondrial anomalies. [...]
2018 - 10.3389/fnins.2018.00342
Frontiers in Neuroscience, Vol. 12 (May 2018) , art. 342  
3.
7 p, 409.8 KB An evolutionary conserved region (ECR) in the human dopamine receptor D4 gene supports reporter gene expression in primary cultures derived from the rat cortex / Paredes, Ursula M. (University of Liverpool. Institute of Translational Medicine) ; Bubb, Vivien J. (University of Liverpool. Institute of Translational Medicine) ; Haddley, Katte (University of Liverpool. Institute of Translational Medicine) ; Macho, Gabriele A. (Institut Català de Paleontologia Miquel Crusafont) ; Quinn, John P. (University of Liverpool. Institute of Translational Medicine)
Background: detecting functional variants contributing to diversity of behaviour is crucial for dissecting genetics of complex behaviours. At a molecular level, characterisation of variation in exons has been studied as they are easily identified in the current genome annotation although the functional consequences are less well understood; however, it has been difficult to prioritise regions of non-coding DNA in which genetic variation could also have significant functional consequences. [...]
2011 - 10.1186/1471-2202-12-46
BMC neuroscience, Vol. 12 (2011) , art. 46  
4.
25 p, 300.6 KB Parafascicular thalamic nucleus deep brain stimulation decreases NMDA receptor GluN1 subunit gene expression in the prefrontal cortex. / Fernández Cabrera, Mónica R. (Universidad Nacional de Educación a Distancia (Espanya). Departamento de Psicobiología) ; Selvas, Abraham (Universidad Nacional de Educación a Distancia (Espanya). Departamento de Psicobiología) ; Miguéns, Miguel (Universidad Nacional de Educación a Distancia (Espanya). Departamento de Psicología Básica I) ; Higuera Matas, Alejandro (Universidad Nacional de Educación a Distancia (Espanya). Departamento de Psicobiología) ; Vale Martínez, Anna (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de les Ciències de la Salut) ; Ambrosio, Emilio (Universidad Nacional de Educación a Distancia (Espanya). Departamento de Psicobiología) ; Martí Nicolovius, Margarita (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de les Ciències de la Salut) ; Guillazo i Blanch, Gemma (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de les Ciències de la Salut)
The rodent parafascicular nucleus (PFn) or the centromedian-parafascicular complex of primates is a posterior intralaminar nucleus of the thalamus related to cortical activation and maintenance of states of consciousness underlying attention, learning and memory. [...]
2017 - 10.1016/j.neuroscience.2017.02.009
Neuroscience, Vol. 348 (April 2017) , p. 73  
5.
14 p, 236.8 KB The AMPA receptor modulator S18986 in the prelimbic cortex enhances acquisition and retention of an odor-reward association / Yefimenko, Natalya (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de les Ciències de la Salut) ; Portero Tresserra, Marta (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de les Ciències de la Salut) ; Martí Nicolovius, Margarita (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de les Ciències de la Salut) ; Guillazo i Blanch, Gemma (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de les Ciències de la Salut) ; Vale Martínez, Anna (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de les Ciències de la Salut)
Systemic administration of S18986, a positive allosteric modulator of AMPA receptors, improves cognition. The present study further characterizes the drug's memory-enhancing properties and is the first to investigate its intracerebral effects on learning and memory. [...]
2013 - 10.1016/j.neulet.2013.05.032
Neuroscience letters, Vol. 548 (2013) , p. 105  
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10 p, 1.4 MB Brain metabolic pattern analysis using a magnetic resonance spectra classification software in experimental stroke / Jiménez Xarrié, Elena (Institut d'Investigació Biomèdica de Sant Pau. Unitat de Malalties Vasculars Cerebrals) ; Dávila Huerta, Myriam (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Candiota Silveira, Ana Paula (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Delgado-Mederos, Raquel (Institut d'Investigació Biomèdica de Sant Pau. Unitat de Malalties Vasculars Cerebrals) ; Ortega-Martorell, Sandra (Liverpool John Moores University. Department of Applied Mathematics) ; Julià Sapé, Ma. Margarita (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Arús i Caraltó, Carles (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Martí-Fàbregas, Joan (Institut d'Investigació Biomèdica de Sant Pau. Unitat de Malalties Vasculars Cerebrals)
Magnetic resonance spectroscopy (MRS) provides non-invasive information about the metabolic pattern of the brain parenchyma in vivo. The SpectraClassifier software performs MRS pattern-recognition by determining the spectral features (metabolites) which can be used objectively to classify spectra. [...]
2017 - 10.1186/s12868-016-0328-x
BMC Neuroscience, Vol. 18, issue 1 (Jan. 2017) , art. 13  
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10 p, 3.4 MB Neuroprotective Effect of Non-viral Gene Therapy Treatment Based on Tetanus Toxin C-fragment in a Severe Mouse Model of Spinal Muscular Atrophy / Oliván, Sara (Universidad de Zaragoza. Centro de Investigación Biomédica en Red en Bioingeniería, Biomateriales y Nanomedicina. Grupo AMB.) ; Calvo, Ana C. (Universidad de Zaragoza. Facultad de Veterinaria. Laboratorio de Genética Bioquímica) ; Rando, Amaya (Universidad de Zaragoza. Facultad de Veterinaria. Laboratorio de Genética Bioquímica) ; Herrando Grabulosa, Mireia (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Manzano, Raquel (University of Oxford. Department of Physiology, Anatomy and Genetics) ; Zaragoza, Pilar (Universidad de Zaragoza. Instituto Agroalimentario de Aragón (IA2)) ; Tizzano, Eduardo F. (Hospital Vall d'Hebron. Àrea de Genètica Clínica i Molecular. Centros de Investigación Biomédica en Red) ; Aguilera Ávila, José (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Osta, Rosario (Universidad de Zaragoza. Centro de Investigación y Tecnología Agroalimentaria de Aragón) ; Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular
Spinal muscular atrophy (SMA) is a hereditary childhood disease that causes paralysis and progressive degeneration of skeletal muscles and spinal motor neurons. SMA is associated with reduced levels of full-length Survival of Motor Neuron (SMN) protein, due to mutations in the Survival of Motor Neuron 1 gene. [...]
2016 - 10.3389/fnmol.2016.00076
Frontiers in Molecular Neuroscience, Vol. 9 (August 2016) , art. 76  
8.
24 p, 5.9 MB Multi-Target Directed Donepezil-Like Ligands for Alzheimer's Disease / Unzeta López, Mercedes (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Esteban, Gerard (Trinity College Dublin. School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute) ; Bolea Tomás, Irene (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Fogel, Wieslawa A. (Medical University of Lodz. Department of Hormone Biochemistry) ; Ramsay, Rona R. (University of St Andrews. Biomedical Sciences Research Complex) ; Youdim, Moussa B. H. (Ruth and Bruce Rappaport Faculty of Medicine. Department of Pharmacology) ; Tipton, Keith F. (Trinity College Dublin. School of Biochemistry and Immunology, Trinity Biomedical Sciences Institute) ; Marco-Contelles, José (Spanish National Research Council. Institute of General Organic Chemistry) ; Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular
HIGHLIGHTS Alzheimer's disease (AD), the most common form of adult onset dementia, is an age-related neurodegenerative disorder characterized by progressive memory loss, decline in language skills, and other cognitive impairments. [...]
2016 - 10.3389/fnins.2016.00205
Frontiers in Neuroscience, Vol. 10 (May 2016) , art. 205  
9.
2 p, 165.1 KB Editorial - Glial Cells : Managers of Neuro-Immunity / Barcia González, Carlos (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Guillemin, Gilles J. (Macquarie University. Department of Biomedical Sciences) ; Curtin, James F. (Dublin Institute of Technology. School of Food Science & Environmental Health) ; Zirger, Jeffrey M. (U.S. Centers for Disease Control and Prevention) ; Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular
After many decades of study in the field of Neuroscience that were mostly centered on the neuron there is a mounting interest in the study of the function of the glial cells in many aspects and functions of the central nervous system. [...]
2016 - 10.3389/fncel.2016.00060
Frontiers in Cellular Neuroscience, Vol. 10 (March 2016) , art.60  
10.
14 p, 750.0 KB Low Cost Eye Tracking : The Current Panorama / Ferhat, Onur (Universitat Autònoma de Barcelona. Departament de Ciències de la Computació) ; Vilariño Freire, Fernando (Universitat Autònoma de Barcelona. Departament de Ciències de la Computació) ; Universitat Autònoma de Barcelona. Centre de Visió per Computador
Despite the availability of accurate, commercial gaze tracker devices working with infrared (IR) technology, visible light gaze tracking constitutes an interesting alternative by allowing scalability and removing hardware requirements. [...]
2016
Computational Intelligence and Neuroscience, Vol. 2016, (March 2016) , Art. 8680541  

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