|
1.
|
|
10 p, 859.5 KB |
Predicting AT(N) pathologies in Alzheimer's disease from blood-based proteomic data using neural networks
/
Zhang, Y. (University of Oxford) ;
Ghose, U. (University of Oxford) ;
Buckley, N.J. (University of Oxford) ;
Engelborghs, S. (Vrije Universiteit Brussel) ;
Sleegers, K. (University of Antwerp) ;
Frisoni, G.B. (Department of Psychiatry. University of Geneva) ;
Wallin, A. (University of Gothenburg) ;
Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ;
Popp, J. (University of Zürich) ;
Martinez-Lage, P. (CITA-Alzheimer Foundation) ;
Legido-Quigley, C. (Steno Diabetes Center) ;
Barkhof, F. (University College London) ;
Zetterberg, H. (Kong Kong Center for Neurodegenerative Diseases) ;
Visser, P.J. (VU University Medical Center) ;
Bertram, L. (University of Oslo) ;
Lovestone, S. (Janssen RD) ;
Nevado-Holgado, Alejo (University of Oxford) ;
Shi, L. (University of Oxford) ;
Universitat Autònoma de Barcelona
Background and objective: Blood-based biomarkers represent a promising approach to help identify early Alzheimer's disease (AD). Previous research has applied traditional machine learning (ML) to analyze plasma omics data and search for potential biomarkers, but the most modern ML methods based on deep learning has however been scarcely explored. [...]
2022 -  10.3389/fnagi.2022.1040001
Frontiers in aging neuroscience, Vol. 14 (29 2022) , p. 1040001
|
|
|
2.
|
|
43 p, 1.3 MB |
Adaptation of the hypothalamus-pituitary-adrenal axis to daily repeated stress does not follow the rules of habituation : A new perspective
/
Rabasa, Cristina (Institute of Neuroscience and Physiology. The Sahlgrenska Academy at University of Gothenburg (Suècia)) ;
Gagliano, Humberto (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Pastor-Ciurana, Jordi (Red Temática de Investigación Cooperativa en Salud (RETICS-Trastornos Adictivos)) ;
Fuentes, Silvia (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de Ciències de la Salut) ;
Belda, Xavier (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Nadal i Alemany, Roser (Universitat Autònoma de Barcelona. Institut de Neurociències) ;
Armario Garcia, Antonio (Universitat Autònoma de Barcelona. Institut de Neurociències)
Repeated exposure to a wide range of stressors differing in nature and intensity results in a reduced response of prototypical stress markers (i. e. plasma levels of ACTH and adrenaline) after an acute challenge with the same (homotypic) stressor. [...]
2015 - 10.1016/j.neubiorev.2015.06.013
Neuroscience and Biobehavioral Reviews, Vol. 56 (september 2015) , p. 35-49
|
|
|
3.
|
|
|
4.
|
|
16 p, 379.2 KB |
Graded photochemical spinal cord injury results in chronic hyperalgesia and depression-like behaviour but no anxiety exacerbation in female BALB/c mice
/
Boadas Vaello, Pere (Universitat de Girona. Departament de Ciències Mèdiques) ;
Homs i Avila, Judit (Universitat de Girona. Departament de Ciències Mèdiques) ;
Portero Tresserra, Marta (Universitat Autònoma de Barcelona. Departament de Psicobiologia i de Metodologia de Ciències de la Salut) ;
Álvarez-Pérez, Beltrán (Universitat de Girona. Departament de Ciències Mèdiques) ;
Deulofeu, Meritxell (Universitat de Girona. Departament de Ciències Mèdiques) ;
Verdú Navarro, Enrique (Universitat de Girona. Departament de Ciències Mèdiques)
Neuropathic pain (NP) is present in 40-to-50% of spinal cord injured patients. It tends to chronicity and correlates with lower quality-of-life. Moreover, the role of NP in the eventual exacerbation of anxiety- and depression-like behaviours during its development and chronification in genetically susceptible individuals remains unclear. [...]
2018 - 10.1016/j.neulet.2017.11.007
Neuroscience Letters, Vol. 664 (2018) , p. 98-106
|
|
|
5.
|
|
11 p, 1.1 MB |
Atrophy in the thalamus but not cerebellum is specific for C9orf72 FTD and ALS patients - An atlas-based volumetric MRI study
/
Schönecker, Sonja (Ludwig-Maximilians-Universität) ;
Neuhofer, Christiane (Ludwig-Maximilians-Universität) ;
Otto, Markus (University of Ulm) ;
Ludolph, Albert (University of Ulm) ;
Kassubek, Jan (University of Ulm) ;
Landwehrmeyer, Bernhard (University of Ulm) ;
Anderl-Straub, Sarah (University of Ulm) ;
Semler, Elisa (University of Ulm) ;
Diehl-Schmid, Janine (Technical University of Munich) ;
Prix, Catharina (Ludwig-Maximilians-Universität) ;
Vollmar, Christian (Ludwig-Maximilians-Universität) ;
Fortea, Juan (Institut d'Investigació Sant Pau) ;
Huppertz, Hans-Jürgen (Swiss Epilepsy Clinic) ;
Arzberger, Thomas (Ludwig-Maximilians-Universität) ;
Edbauer, Dieter (Munich Cluster for Systems Neurology (SyNergy)) ;
Feddersen, Berend (Ludwig-Maximilians-Universität) ;
Dieterich, Marianne (Munich Cluster for Systems Neurology (SyNergy)) ;
Schroeter, Matthias L. (University Hospital Leipzig) ;
Volk, Alexander E. (University Medical Center Hamburg-Eppendorf) ;
Fließbach, Klaus (University Hospital Bonn (Bonn, Alemanya)) ;
Schneider, Anja (University Hospital Bonn (Bonn, Alemanya)) ;
Kornhuber, Johannes (Friedrich-Alexander University Erlangen-Nürnberg) ;
Maler, Manuel (Friedrich-Alexander University Erlangen-Nürnberg) ;
Prudlo, Johannes (German Center for Neurodegenerative Diseases (DZNE)) ;
Jahn, Holger (AMEOS Klinikum Heiligenhafen) ;
Boeckh-Behrens, Tobias (Technical University of Munich) ;
Danek, Adrian (Ludwig-Maximilians-Universität) ;
Klopstock, Thomas (Ludwig-Maximilians-Universität) ;
Levin, Johannes (German Center for Neurodegenerative Diseases (DZNE)) ;
Universitat Autònoma de Barcelona
The neuropathology of patients with frontotemporal dementia (FTD) or amyotrophic lateral sclerosis (ALS) due to a C9orf72 mutation is characterized by two distinct types of characteristic protein depositions containing either TDP-43 or so-called dipeptide repeat proteins that extend beyond frontal and temporal regions. [...]
2018 - 10.3389/fnagi.2018.00045
Frontiers in aging neuroscience, Vol. 10 Núm. FEB (15 2018) , p. 45
|
|
|
6.
|
|
11 p, 814.5 KB |
Amyloid-β, Tau, and Cognition in Cognitively Normal Older Individuals : Examining the Necessity to Adjust for Biomarker Status in Normative Data
/
Bos, Isabelle (Maastricht University) ;
Vos, Stephanie J.B. (Maastricht University) ;
Jansen, Willemijn J. (Maastricht University) ;
Vandenberghe, Rik (KU Leuven) ;
Gabel, Silvy (KU Leuven) ;
Estanga, Ainara (CITA-Alzheimer Foundation) ;
Ecay-Torres, Mirian (CITA-Alzheimer Foundation) ;
Tomassen, Jori (Vrije Universiteit Amsterdam) ;
den Braber, Anouk (Vrije Universiteit Amsterdam) ;
Lleó, Alberto (Institut d'Investigació Biomèdica Sant Pau) ;
Sala, Isabel (Institut d'Investigació Biomèdica Sant Pau) ;
Wallin, Anders (University of Gothenburg Sahlgrenska Academy) ;
Kettunen, Petronella (University of Oxford) ;
Molinuevo, José Luis (Universitat Pompeu Fabra) ;
Rami, Lorena (Hopsital Clínic Consorci Institut D'Investigacions Biomediques August Pi I Sunyer (IDIBAPS)) ;
Chetelat, Gaël (Université de Caen-Normandie GIP Cyceron) ;
de la Sayette, Vincent (CHU de Caen) ;
Tsolaki, Magda (AHEPA University Hospital (Grècia)) ;
Freund-Levi, Yvonne (Norrtälje Hospital Tiohundra) ;
Johannsen, Peter (University of Copenhagen) ;
Novak, Gerald P. (Janssen Pharmaceutical Research and Development) ;
Ramakers, Inez (Maastricht University) ;
Verhey, Frans R. (Maastricht University) ;
Visser, Pieter J. (Vrije Universiteit Amsterdam) ;
Universitat Autònoma de Barcelona
We investigated whether amyloid-β (Aβ) and tau affected cognition in cognitively normal (CN) individuals, and whether norms for neuropsychological tests based on biomarker-negative individuals would improve early detection of dementia. [...]
2018 - 10.3389/fnagi.2018.00193
Frontiers in aging neuroscience, Vol. 10 (25 2018) , p. 193
|
|
|
7.
|
|
104 p, 1.6 MB |
Neurobehavioral and neurodevelopmental profiles of a heuristic genetic model of differential schizophrenia- and addiction-relevant features: The RHA vs. RLA rats
/
Fernández-Teruel, Alberto (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Oliveras, Ignasi (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Cañete, Toni (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Rio-Álamos, Cristóbal (Universidad Austral de Chile. Departamento de Psicologia) ;
Tapias-Espinosa, Carles (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Sampedro-Viana, Daniel (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Sánchez-González, Ana (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Sanna, Francesco (Universitá di Cagliari. Dipartimento di Scienze della vita e dell'ambiente) ;
Torrúbia, Rafael (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
González-Maeso, Javier (Virginia Commonwealth University School of Medicine. Department of Physiology and Biophysics) ;
Driscoll, Peter ;
Morón, Ignacio (Universidad de Granada. Departamento de Psicobiologia) ;
Torres, Carmen (Universidad de Jaén. Departamento de Psicología) ;
Aznar, Susana (Bispebjerg Copenhagen University Hospital) ;
Tobeña, Adolf 1950- (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Corda, Maria G. (Universitá di Cagliari. Dipartimento di Scienze della vita e dell'ambiente) ;
Giorgi, Osvaldo (Universitá di Cagliari. Dipartimento di Scienze della vita e dell'ambiente) ;
Universitat Autònoma de Barcelona.
Institut de Neurociències
The Roman High- (RHA) and Low-(RLA) avoidance rat lines/strains were generated through bidirectional selective breeding for rapid (RHA) vs. extremely poor (RLA) two-way active avoidance acquisition. [...]
2021 - 10.1016/j.neubiorev.2021.09.042
Neuroscience and Biobehavioral Reviews, Vol. 131 (2021) , p. 597-617
|
|
|
8.
|
|
|
9.
|
|
15 p, 895.7 KB |
Semantic processing in bilingual aphasia : Evidence of language dependency
/
Calabria, Marco (Universitat Pompeu Fabra) ;
Grunden, Nicholas (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Serra, Mariona (Universitat Pompeu Fabra) ;
García-Sánchez, Carmen (Institut d'Investigació Biomèdica Sant Pau) ;
Costa, Albert (Institució Catalana de Recerca i Estudis Avançats) ;
Universitat Autònoma de Barcelona
Individuals with aphasia frequently show lexical retrieval deficits due to increased interference of semantically related competitors, a phenomenon that can be observed in tasks such as naming pictures grouped by semantic category. [...]
2019 - 10.3389/fnhum.2019.00205
Frontiers in human neuroscience, Vol. 13 (january 2019) , p. 205
|
|
|
10.
|
|
14 p, 2.9 MB |
A mechanistic account of visual discomfort
/
Penacchio, Olivier (Universitat Autònoma de Barcelona. Departament de Ciències de la Computació .) ;
Otazu Porter, Xavier (Universitat Autònoma de Barcelona. Departament de Ciències de la Computació) ;
Wilkins, Arnold (University of Essex) ;
Haigh, Sarah M. (University of Nevada)
Much of the neural machinery of the early visual cortex, from the extraction of local orientations to contextual modulations through lateral interactions, is thought to have developed to provide a sparse encoding of contour in natural scenes, allowing the brain to process efficiently most of the visual scenes we are exposed to. [...]
2023 - 10.3389/fnins.2023.1200661
Frontiers in Neuroscience, Vol. 17 (July 2023) , art. 1200661
|
|
visitante ::
identificación
alerta personal vía correo electrónico o subscríbase al 
canal RSS.
