UAB Digital Repository of Documents 16 records found  1 - 10next  jump to record: Search took 0.00 seconds. 
1.
5 p, 190.8 KB In silico veritas? Potential limitations for SARS-CoV-2 vaccine development based on T-cell epitope prediction / Silva-Arrieta, Sandra (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Goulder, Phillip J.R. (Ragon Institute of MGH, MIT, and Harvard, Cambridge, Massachusetts, United States of America) ; Brander, C. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa)
2020 - 10.1371/journal.ppat.1008607
PLoS pathogens, Vol. 16 Núm. 6 (january 2020) , p. e1008607  
2.
12 p, 2.4 MB The Risk of sustained sexual transmission of Zika is underestimated / Allard, Antoine (Centre de Recerca Matemàtica) ; Althouse, Benjamin M. (New Mexico State University) ; Hébert-Dufresne, Laurent (University of Vermont) ; Scarpino, Samuel V. (Northeastern University (Boston, Mass.))
Pathogens often follow more than one transmission route during outbreaks—from needle sharing plus sexual transmission of HIV to small droplet aerosol plus fomite transmission of influenza. Thus, controlling an infectious disease outbreak often requires characterizing the risk associated with multiple mechanisms of transmission. [...]
2017 - 10.1371/journal.ppat.1006633
PLoS pathogens, Vol. 13, issue 9 (Sep. 2017) , e1006633  
3.
17 p, 719.5 KB Yeast as a heterologous model system to uncover type III effector function / Popa, Crina (Centre de Recerca en Agrigenòmica) ; Coll, Núria (Centre de Recerca en Agrigenòmica) ; Valls, Marc (Centre de Recerca en Agrigenòmica) ; Sessa, Guido (Tel Aviv University. Department of Molecular Biology and Ecology of Plants)
Type III effectors (T3E) are key virulence proteins that are injected by bacterial pathogens inside the cells of their host to subvert cellular processes and contribute to disease. The budding yeast Saccharomyces cerevisiae represents an important heterologous system for the functional characterisation of T3E proteins in a eukaryotic environment. [...]
2016 - 10.1371/journal.ppat.1005360
PLoS pathogens, Vol. 12, issue 2 (Feb. 2016) , e1005360  
4.
20 p, 1.6 MB PD-L1 Blockade Differentially Impacts Regulatory T Cells from HIV-Infected Individuals Depending on Plasma Viremia / Peligero, Cristina (Infection Biology Laboratory, Department of Experimental and Health Sciences, Universitat Pompeu Fabra) ; Argilaguet, Jordi (Infection Biology Laboratory, Department of Experimental and Health Sciences, Universitat Pompeu Fabra) ; Güerri-Fernandez, Roberto (Parc de Salut Mar. Unitat de Malalties Infeccioses) ; Torres, Berta (Infectious Diseases Unit, Hospital Clínic) ; Ligero, Carmen (Infectious Diseases Unit, Hospital Clínic) ; Colomer, Pilar (Parc de Salut Mar. Unitat de Malalties Infeccioses) ; Plana, Montserrat (Retrovirology and Viral Immunopathology Laboratory, AIDS Research Group, IDIBAPS, Hospital Clínic, University of Barcelona) ; Knobel, Hernando (Parc de Salut Mar. Unitat de Malalties Infeccioses) ; García, Felipe (Infectious Diseases Unit, Hospital Clínic) ; Meyerhans, Andreas (Institució Catalana de Recerca i Estudis Avançats (ICREA)) ; Universitat Autònoma de Barcelona
Blocking the PD-1/PD-L1 pathway has emerged as a potential therapy to restore impaired immune responses in human immunodeficiency virus (HIV)-infected individuals. Most reports have studied the impact of the PD-L1 blockade on effector cells and neglected possible effects on regulatory T cells (Treg cells), which play an essential role in balancing immunopathology and antiviral effector responses. [...]
2015 - 10.1371/journal.ppat.1005270
PLoS pathogens, Vol. 11 (december 2015)  
5.
9 p, 915.2 KB HIV-1 Capture and Transmission by Dendritic Cells : The Role of Viral Glycolipids and the Cellular Receptor Siglec-1 / Izquierdo-Useros, Nuria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Lorizate, Maier (Universidad del Pais Vasco. Unidad de Biofisica (CSIC-UPV/EHU) y Departamento de Bioquímica,) ; McLaren, Paul J. (University Hospital Center and University of Lausanne. Institute of Microbiology) ; Telenti, Amalio (University Hospital Center and University of Lausanne. Institute of Microbiology) ; Kräusslich, Hans-Georg (Universitätsklinikum Heidelberg. Department of Infectious Diseases, Virology) ; Martinez-Picado, Javier (Institució Catalana de Recerca i Estudis Avançats (ICREA)) ; Universitat Autònoma de Barcelona
Dendritic cells (DCs) are essential in order to combat invading viruses and trigger antiviral responses. Paradoxically, in the case of HIV-1, DCs might contribute to viral pathogenesis through trans -infection, a mechanism that promotes viral capture and transmission to target cells, especially after DC maturation. [...]
2014 - 10.1371/journal.ppat.1004146
PLoS pathogens, Vol. 10 (july 2014)  
6.
11 p, 527.4 KB Deep Molecular Characterization of HIV-1 Dynamics under Suppressive HAART / Buzón, Maria J. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Codoñer, Francisco M. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Frost, Simon D. W. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Puertas, Maria C. (Institut de Recerca de la SIDA, IrsiCaixa, Hospital Universitari Germans Trias i Pujol, Universitat Autònoma de Barcelona, Badalona, Spain) ; Massanella, Marta (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Dalmau, Judith (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Llibre, Josep M. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Stevenson, Mario (University of Miami Miller School of Medicine, Miami, Florida, United States of America) ; Blanco, Julià (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Clotet, Bonaventura (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Paredes, Roger (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Martinez-Picado, Javier (Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain) ; Universitat Autònoma de Barcelona
In order to design strategies for eradication of HIV-1 from infected individuals, detailed insight into the HIV-1 reservoirs that persist in patients on suppressive antiretroviral therapy (ART) is required. [...]
2011 - 10.1371/journal.ppat.1002314
PLoS pathogens, Vol. 7 (october 2011)  
7.
13 p, 954.1 KB Viral protein inhibits RISC activity by argonaute binding through conserved WG/GW motifs / Giner, Ana (Centre de Recerca en Agrigenòmica) ; Lakatos, Lóránt (Agricultural Biotechnology Center (Hungria)) ; Garcia i Chapa, Meritxell (Centre de Recerca en Agrigenòmica) ; López-Moya, Juan José (Centre de Recerca en Agrigenòmica) ; Burgyán, József (Agricultural Biotechnology Center (Hungria))
RNA silencing is an evolutionarily conserved sequence-specific gene-inactivation system that also functions as an antiviral mechanism in higher plants and insects. To overcome antiviral RNA silencing, viruses express silencing-suppressor proteins. [...]
2010 - 10.1371/journal.ppat.1000996
Plos pathogens, Vol. 6, no. 7 (July 2010) , e1000996  
8.
36 p, 3.8 MB Small RNA-based antiviral defense in the phytopathogenic fungus Colletotrichum higginsianum / Campo Sánchez, Sonia (Centre de Recerca en Agrigenòmica) ; Gilbert, Kerrigan B. (Donald Danforth Plant Science Center) ; Carrington, James C. (Donald Danforth Plant Science Center)
Even though the fungal kingdom contains more than 3 million species, little is known about the biological roles of RNA silencing in fungi. The Colletotrichum genus comprises fungal species that are pathogenic for a wide range of crop species worldwide. [...]
2016 - 10.1371/journal.ppat.1005640
Plos pathogens, Vol. 12, no. 6 (June 2016) , e1005640  
9.
22 p, 3.3 MB The G1/S Specific Cyclin D2 Is a Regulator of HIV-1 Restriction in Non-proliferating Cells / Badia, Roger (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Pujantell, Maria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Riveira Muñoz, Eva (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Puig, Teresa (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Torres Torronteras, Javier (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Martí Seves, Ramon (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Clotet, Bonaventura (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Ampudia, Rosa Maria (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Vives Pi, Marta (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Esté, José (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Ballana, Ester (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa)
Macrophages are a heterogeneous cell population strongly influenced by differentiation stimuli that become susceptible to HIV-1 infection after inactivation of the restriction factor SAMHD1 by cyclin-dependent kinases (CDK). [...]
2016 - 10.1371/journal.ppat.1005829
PLoS pathogens, Vol. 12 Núm. 8 (August 2016)  
10.
4 p, 289.4 KB Malassezia Yeasts : How Many Species Infect Humans and Animals? / Cabañes Sáenz, Francisco Javier (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals)
2014 - 10.1371/journal.ppat.1003892
PLoS pathogens, Vol. 10 Issue 2 (February 2014)  

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