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10 p, 1.1 MB |
Usefulness of real-time PCR during follow-up of patients treated with Benznidazole for chronic Chagas disease : Experience in two referral centers in Barcelona
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Sulleiro, Elena (Hospital Universitari Vall d'Hebron) ;
Silgado, Aroa (Hospital Universitari Vall d'Hebron) ;
Serre-Delcor, Núria (Hospital Universitari Vall d'Hebron) ;
Salvador, Fernando (Hospital Universitari Vall d'Hebron) ;
Tavares de Oliveira, Maykon (Departamento de Clínica médica, Unidade de Cardiologia, Faculdade de Medicina de Ribeirão Preto, Universidade de São Paulo, São Paulo, Brazil) ;
Moure García, Zaira (Hospital Universitari Vall d'Hebron) ;
Sao-Aviles, Augusto (Hospital Universitari Vall d'Hebron) ;
Oliveira, Inés (Hospital Universitari Vall d'Hebron) ;
Treviño Maruri , Begoña (Hospital Universitari Vall d'Hebron) ;
Goterris, Lidia (Hospital Universitari Vall d'Hebron) ;
Sánchez-Montalvá, Adrián (Hospital Universitari Vall d'Hebron) ;
Pou, Diana (Hospital Universitari Vall d'Hebron) ;
Molina, Israel (Hospital Universitari Vall d'Hebron) ;
Pumarola Suñé, Tomàs (Hospital Universitari Vall d'Hebron) ;
Universitat Autònoma de Barcelona
Antitrypanosomal treatment with Benznidazole (BZ) or Nifurtimox may be recommended for patients with chronic Chagas disease (CD) to reduce the onset or progression of symptoms. However, such treatment has limited efficacy and high level of toxic effects. [...]
2020 -  10.1371/journal.pntd.0008067
PLoS neglected tropical diseases, Vol. 14 (february 2020)
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2.
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25 p, 6.8 MB |
Understanding legal trade of cattle and camels and the risk of rift valley fever introduction into Egypt
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Napp Avelli, Sebastián (Universitat Autònoma de Barcelona. Centre de Recerca en Sanitat Animal) ;
Chevalier, Veronique (CIRAD, UPR AGIRs, Montpellier, France) ;
Busquets, Núria (Universitat Autònoma de Barcelona. Centre de Recerca en Sanitat Animal) ;
Calistri, Paolo (Food and Agriculture Organization of the United Nations (FAO)) ;
Casal i Fàbrega, Jordi (Universitat Autònoma de Barcelona. Departament de Sanitat i d'Anatomia Animals) ;
Attia, Mohamed (Egypt. Ministry of Agriculture and Land Reclamation. Central Administration of Preventive Medicine) ;
Elbassal, Rehab (Egypt. Ministry of Agriculture and Land Reclamation. Department of Epidemiology) ;
Hosni, Heba (Egypt. Ministry of Agriculture and Land Reclamation. Department of Epidemiology) ;
Farrag, Hatem (Egypt. Ministry of Agriculture and Land Reclamation. Quarantine & Inspection Department) ;
Hassan, Noura (Egypt. Ministry of Agriculture and Land Reclamation. Quarantine & Inspection Department) ;
Tawfik, Rasha (Egypt. Ministry of Agriculture and Land Reclamation. Quarantine & Inspection Department) ;
Abd Elkader Sohair (Egypt. Ministry of Agriculture and Land Reclamation. Central Administration of Preventive Medicine) ;
Bayomy, Shanin (Egypt. Ministry of Agriculture and Land Reclamation. Department of Epidemiology)
Rift Valley Fever (RVF) is a mosquito-borne zoonosis, which may cause significant losses for the livestock sector and have serious public health implications. Egypt has been repeatedly affected by RVF epidemics, mainly associated to the importation of animals from subSaharan countries, where the disease is endemic. [...]
2018 - 10.1371/journal.pntd.0006143
PLoS neglected tropical diseases, Vol. 12 (2018) , p. e0006143
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3.
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8 p, 1.4 MB |
Plasmodium vivax gametocytes in the bone marrow of an acute malaria patient and changes in the erythroid miRNA profile
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Baro, Barbara (Fundação de Medicina Tropical Dr. Heitor Vieira Dourado) ;
Deroost, Katrien (Fundação de Medicina Tropical Dr. Heitor Vieira Dourado) ;
Raiol, Tainá (Fundação Oswaldo Cruz - Instituto Leônidas e Maria Deane) ;
Brito, Marcelo (Fundação de Medicina Tropical Dr. Heitor Vieira Dourado) ;
Almeida, Anne C.G. (Fundação de Medicina Tropical Dr. Heitor Vieira Dourado) ;
de Menezes-Neto, Armando (Institut de Salut Global de Barcelona) ;
Figueiredo, Erick F. G. (Fundação de Medicina Tropical Dr. Heitor Vieira Dourado) ;
Alencar, Aline (Fundação de Medicina Tropical Dr. Heitor Vieira Dourado) ;
Leitão, Rodrigo (Fundação Hospitalar de Hematologia e Hematoterapia do Amazonas(HEMOAM)) ;
Val, Fernando (Fundação de Medicina Tropical Dr. Heitor Vieira Dourado) ;
Monteiro, Wuelton (Fundação de Medicina Tropical Dr. Heitor Vieira Dourado) ;
Oliveira, Anna (Institut Germans Trias i Pujol) ;
Armengol, Maria del Pilar (Institut Germans Trias i Pujol) ;
Fernández Becerra, Carmen (Institut de Salut Global de Barcelona) ;
Lacerda, Marcus V. (Fundação de Medicina Tropical Dr. Heitor Vieira Dourado) ;
del Portillo, Hernando A. (Institut de Salut Global de Barcelona) ;
Universitat Autònoma de Barcelona
2017 - 10.1371/journal.pntd.0005365
PLOS Neglected Tropical Diseases, Vol. 11 Núm. 4 (2017) , p. 1-8
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22 p, 8.6 MB |
The ubiquitin-conjugating enzyme CDC34 is essential for cytokinesis in contrast to putative subunits of a SCF complex in Trypanosoma brucei
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Rojas, Federico (Instituto de Investigaciones en Ingeniería Genética y Biología Molecular (Buenos Aires)) ;
Koszela, Joanna (University of Edinburgh Medical School. College of Medicine and Veterinary Medicine) ;
Búa, Jacqueline E. (Instituto Nacional de Diagnostico e Investigacion de la Enfermedad de Chagas Dr. Mario Fatala Chaben) ;
Llorente, Briardo (Centre de Recerca en Agrigenòmica) ;
Burchmore, Richard Js (University of Glasgow. Institute of Infection, Immunity and Inflammation) ;
Auer, Manfred (University of Edinburgh Medical School. College of Medicine and Veterinary Medicine) ;
Mottram, Jeremy C. (University of York. Department of Biology) ;
Téllez-Iñón, María Teresa (Instituto de Investigaciones en Ingeniería Genética y Biología Molecular (Buenos Aires))
The ubiquitin-proteasome system is a post-translational regulatory pathway for controlling protein stability and activity that underlies many fundamental cellular processes, including cell cycle progression. [...]
2017 - 10.1371/journal.pntd.0005626
PLoS neglected tropical diseases, Vol. 11 Núm. 6 (2017) , e0005626
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5.
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16 p, 1.9 MB |
Safety and pharmacokinetic profile of fixed-dose ivermectin with an innovative 18mg tablet in healthy adult volunteers
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Muñoz, Jose (Barcelona Institute for Global Health (ISGlobal)) ;
Ballester, Maria Rosa (Institut d'Investigació Biomèdica Sant Pau) ;
Antonijoan Arbós, Rosa Ma. (Rosa María) (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ;
Gich Saladich, Ignasi (Universitat Autònoma de Barcelona. Departament de Farmacologia, de Terapèutica i de Toxicologia) ;
Rodríguez, Montse (Institut d'Investigació Biomèdica Sant Pau) ;
Colli, Enrico (ExeltisPharma, Chemo group. Madrid, Spain) ;
Gold, Silvia (Fundacion Mundo Sano, Buenos Aires, Argentina) ;
Krolewiecki, Alejandro J. (Instituto de Investigaciones en Enfermedades Tropicales, Universidad Nacional de Salta/CONICET, Oran, Argentina) ;
Universitat Autònoma de Barcelona
ClinicalTrials. gov . Current efforts for the control of poverty-related diseases provide drug treatments through mass drug administration (MDA) as a key component. Ivermectin is an antiparasitary drug which has been used to fight some of these diseases, and millions of treatments have been distributed with a favorable toxicity profile. [...]
2018 - 10.1371/journal.pntd.0006020
PLoS neglected tropical diseases, Vol. 12 (january 2018)
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6.
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27 p, 41.7 MB |
Geographic patterns and environmental factors associated with human yellow fever presence in the Americas
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Hamrick, Patricia Najera (PAHO Health Emergencies Department, Pan American Health Organization) ;
Aldighieri, Sylvain (PAHO Health Emergencies Department, Pan American Health Organization, Washington D.C., United States of America) ;
Machado, Gustavo (Veterinary Population Medicine Department, University of Minnesota, Saint Paul, Minnesota, United States of America) ;
Leonel, Deise Galan (PAHO Health Emergencies Department, Pan American Health Organization, Washington D.C., United States of America) ;
Vilca, Luz Maria (Hospital Universitari Vall d'Hebron) ;
Uriona, Sonia (Hospital Universitari Vall d'Hebron) ;
Schneider, Maria Cristina (PAHO Health Emergencies Department, Pan American Health Organization, Washington D.C., United States of America) ;
Universitat Autònoma de Barcelona
In the Americas, yellow fever virus transmission is a latent threat due to the proximity between urban and wild environments. Although yellow fever has nearly vanished from North and Central America, there are still 13 countries in the Americas considered endemic by the World Health Organization. [...]
2017 - 10.1371/journal.pntd.0005897
PLoS neglected tropical diseases, Vol. 11 (september 2017)
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7.
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11 p, 917.9 KB |
High Resolution Esophageal Manometry in Patients with Chagas Disease : A Cross-Sectional Evaluation
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Sánchez-Montalvá, Adrián (Hospital Universitari Vall d'Hebron) ;
Moris, Maria (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Mego, Marianela (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Salvador, Fernando (Hospital Universitari Vall d'Hebron) ;
Accarino, Ana María (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Ramírez, Kathleen (Hospital Universitari Vall d'Hebron) ;
Azpiroz Vidaur, Fernando (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Ruiz-de-Leon, Antonio (Department of Gastroenterology, University Hospital San Carlos, Universidad Complutense) ;
Molina, Israel (Hospital Universitari Vall d'Hebron) ;
Universitat Autònoma de Barcelona.
Departament de Medicina ;
Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (Ciberehd)
Gastrointestinal involvement affects 30-40% of the patients with chronic Chagas disease. Esophageal symptoms appear once the structural damage is established. Little is known about the usefulness of high resolution manometry to early identification of esophageal involvement. [...]
2016 - 10.1371/journal.pntd.0004416
PLoS neglected tropical diseases, Vol. 10 (february 2016)
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8.
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20 p, 2.1 MB |
Sequence- and structure-based immunoreactive epitope discovery for Burkholderia pseudomallei flagellin
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Nithichanon, Arnone (Khon Kaen University. Centre for Research and Development of Medical Diagnostic Laboratories) ;
Rinchai, Darawan (Khon Kaen University. Centre for Research and Development of Medical Diagnostic Laboratories) ;
Gori, Alessandro (Consiglio Nazionale delle Ricerche. Istituto di Chimica del Riconoscimento Molecolare) ;
Lassaux, Patricia (Università degli Studi di Milano. Centro di Eccellenza Interdisciplinare Materiali e Interfacce Nanostrutturati) ;
Peri, Claudio (Consiglio Nazionale delle Ricerche. Istituto di Chimica del Riconoscimento Molecolare) ;
Conchillo-Solé, Oscar (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Ferrer Navarro, Mario (Universitat de Barcelona. Departament de Microbiologia Clínica) ;
Gourlay, Louise J. (Università degli Studi di Milano. Centro di Eccellenza Interdisciplinare Materiali e Interfacce Nanostrutturati) ;
Nardini, Marco (Università degli Studi di Milano. Centro di Eccellenza Interdisciplinare Materiali e Interfacce Nanostrutturati) ;
Vila, Jordi (Universitat de Barcelona. Departament de Microbiologia Clínica) ;
Daura i Ribera, Xavier (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Colombo, Giorgio (Consiglio Nazionale delle Ricerche. Istituto di Chimica del Riconoscimento Molecolare) ;
Bolognesi, Martino (Università degli Studi di Milano. Centro di Eccellenza Interdisciplinare Materiali e Interfacce Nanostrutturati) ;
Lertmemonkolchai, Ganjana (Khon Kaen University. Centre for Research and Development of Medical Diagnostic Laboratories)
Burkholderia pseudomallei is a Gram-negative bacterium responsible for melioidosis, a serious and often fatal infectious disease that is poorly controlled by existing treatments. Due to its inherent resistance to the major antibiotic classes and its facultative intracellular pathogenicity, an effective vaccine would be extremely desirable, along with appropriate prevention and therapeutic management. [...]
2015 - 10.1371/journal.pntd.0003917
PLoS neglected tropical diseases, Vol. 9, Issue 7 (July 2015) , e0003917
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