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12 p, 745.4 KB |
Choice of the initial antiretroviral treatment for HIV-positive individuals in the era of integrase inhibitors
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Alejos, Belén (Centro Nacional de Epidemiologia. Instituto de Salud Carlos III) ;
Suárez-García, Inés (Hospital Universitario Infanta Sofia) ;
Bisbal, Otilia (Hospital 12 de Octubre (Madrid)) ;
Iribarren, José Antonio (Hospital de Donostia (Sant Sebastià, País Basc)) ;
Asensi, Víctor (Hospital Universitario Central de Asturias) ;
Górgolas, Miguel (Hospital Universitario Fundación Jiménez Díaz) ;
Muga, Roberto (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Moreno, Santiago (Hospital Universitario Ramón y Cajal (Madrid)) ;
Jarrin, Inma (Centro Nacional de Epidemiología. Instituto de Salud Carlos III) ;
CoRIS, Cohort
Background We aimed to describe the most frequently prescribed initial antiretroviral therapy (ART) regimens in recent years in HIV-positive persons in the Cohort of the Spanish HIV/AIDS Research Network (CoRIS) and to investigate factors associated with the choice of each regimen. [...]
2019 - 10.1371/journal.pone.0221598
PloS one, Vol. 14 Núm. 8 (2019) , art. e0221598
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27 p, 1.6 MB |
Exploring the ovine sperm transcriptome by RNAseq techniques : I Effect of seasonal conditions on transcripts abundance
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Ureña, Irene (CSIC-INIA. Departamento de Mejora Genetica Animal) ;
Gonzalez, Carmen (CSIC-INIA. Departamento de Mejora Genetica Animal) ;
Ramon, Manuel (IRIAF-CERSYRA) ;
Gòdia, Marta (Centre de Recerca en Agrigenòmica) ;
Clop, Alex (Centre de Recerca en Agrigenòmica) ;
Calvo Lacosta, Jorge Hugo (Centro de Investigación y Tecnología Agroalimentaria de Aragón) ;
Carabaño, M. Jesús (CSIC-INIA. Departamento de Mejora Genetica Animal) ;
Serrano, Magdalena (CSIC-INIA. Departamento de Mejora Genetica Animal)
Understanding the cell molecular changes occurring as a results of climatic circumstances is crucial in the current days in which climate change and global warming are one of the most serious challenges that living organisms have to face. [...]
2022 - 10.1371/journal.pone.0264978
PloS one, Vol. 17, Num. 3 (March 2022) , art. e0264978
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26 p, 11.6 MB |
Unique trackway on Permian Karoo shoreline provides evidence of temnospondyl locomotory behaviour
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Groenewald, David (University of the Witwatersrand. Evolutionary Studies Institute) ;
Krüger, Ashley (Swedish Museum of Natural History) ;
Day, Michael Oliver (Natural History Museum) ;
Penn-Clarke, Cameron (University of the Witwatersrand. Evolutionary Studies Institute) ;
Hancox, John P. (University of the Witwatersrand. Evolutionary Studies Institute) ;
Rubidge, Bruce S. (University of the Witwatersrand. Evolutionary Studies Institute)
Large-bodied temnospondyl amphibians were the dominant predators in non-marine aquatic ecosystems from the Carboniferous to the Middle Triassic. In the Permian-aged lower Beaufort Group of the main Karoo Basin, South Africa, temnospondyls are represented exclusively by the family Rhinesuchidae and are well represented by body fossils, whereas trace fossils are scarce. [...]
2023 - 10.1371/journal.pone.0282354
PloS one, Vol. 18, Issue 3 (March 2023) . art. e0282354
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14 p, 1.6 MB |
Methodological transparency of preoperative clinical practice guidelines for elective surgery. Systematic review
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Angel, Gustavo (Universidad del Cauca (Cauca, Colòmbia). Departamento de Anestesiología) ;
Trujillo, Cristian (Universidad del Cauca (Cauca, Colòmbia). Departamento de Anestesiología) ;
Mallama, Mario (Universidad del Cauca (Cauca, Colòmbia). Departamento de Anestesiología) ;
Alonso-Coello, Pablo (Institut d'Investigació Biomèdica Sant Pau) ;
Klimek, Markus (Erasmus University Medical Centre Rotterdam. Department of Anesthesiology) ;
Calvache, Jose A. (Erasmus University Medical Centre Rotterdam. Department of Anesthesiology) ;
Universitat Autònoma de Barcelona
Clinical practice guidelines (CPG) are statements that provide recommendations regarding the approach to different diseases and aim to increase quality while decreasing the risk of complications in health care. [...]
2023 - 10.1371/journal.pone.0272756
PloS one, Vol. 18 (february 2023)
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14 p, 1014.0 KB |
Socioeconomic disparities in suicide : Causation or confounding?
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Lorant, V. (Institute of Health and Society. UCLouvain) ;
Kapadia, D. (University of Manchester) ;
Perelman, J. (Universidade NOVA de Lisboa) ;
Borrell i Thió, Carme (Institut d'Investigació Biomèdica Sant Pau) ;
Rodríguez-Sanz, Maica (Institut d'Investigació Biomèdica Sant Pau) ;
Kalediene, R. ;
Leinsalu, M. ;
Regidor, E. ;
Wojtyniak, B. ;
Strand, B.H. ;
Bopp, M. ;
Mackenbach, J.
Background Despite an overall reduction in suicide, educational disparities in suicide have not decreased over the last decade. The mechanisms behind educational disparities in suicide, however, remain unclear: low educational status may increase the risk of suicide ("causation") or low educational status and suicide may share confounders. [...]
2021 - 10.1371/journal.pone.0243895
PloS one, Vol. 16 Núm. 1 January (january 2021) , p. e0243895
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20 p, 1.3 MB |
Early prognostic performance of miR155-5p monitoring for the risk of rejection : Logistic regression with a population pharmacokinetic approach in adult kidney transplant patients
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Quintairos, L. (Hospital Clínic i Provincial de Barcelona) ;
Colom, Helena (Universitat de Barcelona. Departament de Farmacologia, Toxicologia i Química Terapèutica) ;
Millan, O. (Instituto de Salud Carlos III) ;
Fortuna, V. (Hospital Clínic i Provincial de Barcelona) ;
Espinosa, C. (Hospital Clínic i Provincial de Barcelona) ;
Guirado, Luis (Institut d'Investigació Biomèdica Sant Pau) ;
Budde, K. (Charité - Universitätsmedizin Berlin) ;
Sommerer, C. (Heidelberg University Hospital (Alemanya)) ;
Lizana, A. (Hospital Clínic i Provincial de Barcelona) ;
Lopez-Pua, Y. (Hospital Clínic i Provincial de Barcelona) ;
Brunet, M. (Instituto de Salud Carlos III)
Previous results from our group and others have shown that urinary pellet expression of miR155-5p and urinary CXCL-10 production could play a key role in the prognosis and diagnosis of acute rejection (AR) in kidney transplantation patients. [...]
2021 - 10.1371/journal.pone.0245880
PloS one, Vol. 16 Núm. 1 January (january 2021) , p. e0245880
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14 p, 846.4 KB |
Real world effectiveness of standard of care triple therapy versus two-drug combinations for treatment of people living with HIV
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Teira, Ramón (Hospital de Sierrallana) ;
Diaz-Cuervo, Helena (Gilead Sciences. Medical Affairs) ;
Aragão, Filipa (NOVA National School of Public Health. Public Health Research Centre. Lisboa) ;
Marguet, Sophie (Amaris Consulting. Health Economics and Market Access (HEMA)) ;
de la Fuente, Belén (Hospital Universitario de Cabueñes (Gijón)) ;
Muñoz, María José (Hospital de Basurto (Bilbao, Biscaia)) ;
Abdulghani, Nadia (Hospital Arnau de Vilanova (València)) ;
Ribera, Esteban (Hospital Universitari Vall d'Hebron) ;
Domingo, Pere (Institut d'Investigació Biomèdica Sant Pau) ;
Deig, Elisabeth (Hospital General) ;
Peraire, Joaquim (Hospital Universitari Joan XXIII de Tarragona) ;
Roca, Bernardino (Hospital General) ;
Montero, Marta (Hospital La Fé) ;
Galindo, María José (Hospital Clínico) ;
Romero, Alberto (Hospital Universitario de Puerto Real) ;
Espinosa, Nuria (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Lozano, Fernando (Hospital Universitario Virgen de Valme (Sevilla, Andalusia)) ;
Merino, María Dolores (Hospital Infanta Elena) ;
Martínez, Elisa (Complejo Hospitalario Universitario de Albacete) ;
Geijo, Paloma (Hospital Virgen de La Luz (Cuenca)) ;
Estrada, Vicente (Hospital Clínico San Carlos (Madrid)) ;
García, Josefina (Hospital Santa Lucía) ;
Sepúlveda, María Antonia (Hospital Virgen de la Salud (Toledo)) ;
Berenguer, Juan (Hospital General Universitario Gregorio Marañón)
BACKGROUND: Since 1996, the standard of care (SOC) therapy for HIV treatment has consisted of a backbone of two nucleoside analogue reverse transcriptase inhibitors (NRTI) paired with a third agent. Use of two-drug combinations (2DC) has been considered for selected patients to avoid toxicities associated with the use of NRTIs. [...]
2021 - 10.1371/journal.pone.0249515
PloS one, Vol. 16 Núm. 4 (2021) , p. e0249515
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