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18 p, 205.0 KB Taxane-Induced Peripheral Neurotoxicity / Velasco Fargas, Roser (Hospital Universitari de Bellvitge-ICO Duran i Reynals, Unit of Neuro-Oncology) ; Bruna Escuer, Jordi (Universitat Autònoma de Barcelona. Institut de Neurociències)
Taxane-derived agents are chemotherapy drugs widely employed in cancer treatment. Among them, paclitaxel and docetaxel are most commonly administered, but newer formulations are being investigated. Taxane antineoplastic activity is mainly based on the ability of the drugs to promote microtubule assembly, leading to mitotic arrest and apoptosis in cancer cells. [...]
2015 - 10.3390/toxics3020152
Toxics, Vol. 3 Núm. 2 (April 2015) , p. 152-169  

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