UAB Digital Repository of Documents 4 records found  Search took 0.02 seconds. 
1.
3 p, 604.1 KB Complete Resolution of Symptoms of Primary Orthostatic Tremor with Perampanel / Ruiz Julián, María (Institut d'Investigació Biomèdica Sant Pau) ; Orozco, Jorge Luís (Institut d'Investigació Biomèdica Sant Pau) ; Gironell, Alexandre (Institut d'Investigació Biomèdica Sant Pau)
Primary orthostatic tremor (POT) is an infrequent disorder whose physiopathology is unknown. Current medication is largely ineffective or only offers mild benefits. A 75-year-old female with refractory POT treated with 4 mg/day of perampanel achieved complete symptom resolution. [...]
2018 - 10.7916/D8QZ3SZD
Tremor and Other Hyperkinetic Movements, Vol. 8 (april 2018)  
2.
4 p, 595.0 KB Ethosuximide for Essential Tremor : An Open-Label Trial / Gironell, Alexandre (Institut d'Investigació Biomèdica Sant Pau) ; Marin Lahoz, Juan (Institut d'Investigació Biomèdica Sant Pau) ; Universitat Autònoma de Barcelona
T-type calcium channel activation has been postulated to underlie rhythmicity in the olivo-cerebellar system that is implicated in ET. Ethosuximide reduces T-type calcium currents and can suppress tremor in two animal models of ET. [...]
2016 - 10.7916/D8FQ9WN0
Tremor and Other Hyperkinetic Movements, Vol. 6 (july 2016)  
3.
5 p, 916.8 KB Severity Stages in Essential Tremor : A Long-Term Retrospective Study Using the Glass Scale / Gironell, Alexandre (Institut d'Investigació Biomèdica Sant Pau) ; Ribosa-Nogué, Roser (Institut d'Investigació Biomèdica Sant Pau) ; Gich, Ignasi (Institut d'Investigació Biomèdica Sant Pau) ; Marin-Lahoz, Juan (Institut d'Investigació Biomèdica Sant Pau) ; Pascual-Sedano, Berta (Institut d'Investigació Biomèdica Sant Pau) ; Universitat Autònoma de Barcelona. Departament de Medicina
Few prospective studies have attempted to estimate the rate of decline of essential tremor (ET) and these were over a relatively short time period (less than 10 years). We performed a long-term study of severity stages in ET using the Glass Scale scoring system. [...]
2015 - 10.7916/D8DV1HQC
Tremor and Other Hyperkinetic Movements, Vol. 5 (march 2015)  
4.
9 p, 1.2 MB The GABA Hypothesis in Essential Tremor : Lights and Shadows / Gironell, Alexandre (Institut d'Investigació Biomèdica Sant Pau) ; Universitat Autònoma de Barcelona
The gamma-aminobutyric acid (GABA) hypothesis in essential tremor (ET) implies a disturbance of the GABAergic system, especially involving the cerebellum. This review examines the evidence of the GABA hypothesis. [...]
2014 - 10.7916/D8SF2T9C
Tremor and Other Hyperkinetic Movements, Vol. 4 (july 2014)  

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