Dipòsit Digital de Documents de la UAB 14 registres trobats  1 - 10següent  anar al registre: La cerca s'ha fet en 0.01 segons. 
1.
8 p, 1.0 MB Preliminary paleohistological observations of the StW 573 ('Little Foot') skull / Beaudet, Amélie (Institut Català de Paleontologia Miquel Crusafont) ; Atwood, Robert C (Diamond Light Source Ltd.) ; Kockelmann, Winfried (STFC-Rutherford Appleton Laboratory) ; Fernandez, Vincent (Natural History Museum (Londres, Anglaterra). Core Research Laboratories) ; Connolley, Thomas (Diamond Light Source Ltd.) ; Vo, Nghia Trong (Diamond Light Source Ltd.) ; Clarke, Ronald (University of the Witwatersrand. Evolutionary Studies Institute) ; Stratford, Dominic (University of the Witwatersrand. School of Geography, Archaeology and Environmental Studies)
Numerous aspects of early hominin biology remain debated or simply unknown. However, recent developments in high-resolution imaging techniques have opened new avenues in the field of paleoanthropology. [...]
2021 - 10.7554/eLife.64804
eLife, Vol. 10 (March 2021)  
2.
33 p, 5.1 MB The evolution of the vestibular apparatus in apes and humans / Urciuoli, Alessandro (Institut Català de Paleontologia Miquel Crusafont) ; Zanolli, Clément (Université de Bordeaux. Centre National de la Recherche Scientifique. Laboratoire PACEA (France)) ; Beaudet, Amélie (University of Pretoria. Department of Anatomy (South Africa)) ; Dumoncel, Jean (Centre National de la Recherche Scientifique (França)) ; Santos, Frédéric (Université de Bordeaux. Centre National de la Recherche Scientifique. Laboratoire PACEA (France)) ; Moyà Solà, Salvador (Institut Català de Paleontologia Miquel Crusafont) ; Alba, David M. (Institut Català de Paleontologia Miquel Crusafont) ; Universitat Autònoma de Barcelona. Departament de Biologia Animal, de Biologia Vegetal i d'Ecologia
Phylogenetic relationships among extinct hominoids (apes and humans) are controversial due to pervasive homoplasy and the incompleteness of the fossil record. The bony labyrinth might contribute to this debate, as it displays strong phylogenetic signal among other mammals. [...]
2020 - 10.7554/eLife.51261
eLife, Vol. 9 (March 2020) , art. e51261  
3.
16 p, 1.5 MB Adaptation of hydroxymethylbutenyl diphosphate reductase enables volatile isoprenoid production / Bongers, Mareike (The University of Queensland. Australian Institute for Bioengineering and Nanotechnolog (Australia)) ; Pérez-Gil, Jordi (Centre de Recerca en Agrigenòmica) ; Hodson, Mark P. (The University of Queensland. Australian Institute for Bioengineering and Nanotechnolog (Australia)) ; Schrübbers, Lars (Technical University of Denmark. Novo Nordisk Foundation Center for Biosustainability (Denmark)) ; Wulff, Tune (Technical University of Denmark. Novo Nordisk Foundation Center for Biosustainability (Denmark)) ; Sommer, Morten O.A. (Technical University of Denmark. Novo Nordisk Foundation Center for Biosustainability (Denmark)) ; Nielsen, Lars K. (The University of Queensland. Australian Institute for Bioengineering and Nanotechnolog (Australia)) ; Vickers, Claudia E. (CSIRO Synthetic Biology Future Science Platform (Australia))
Volatile isoprenoids produced by plants are emitted in vast quantities into the atmosphere, with substantial effects on global carbon cycling. Yet, the molecular mechanisms regulating the balance between volatile and non-volatile isoprenoid production remain unknown. [...]
2020 - 10.7554/eLife.48685
eLife, Vol. 9 (March 2020) , art. e48685
2 documents
4.
22 p, 4.5 MB CNApp, a tool for the quantification of copy number alterations and integrative analysis revealing clinical implications / Franch-Expósito, Sebastià (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Bassaganyas, Laia (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Vila-Casadesús, Maria (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ; Hernández-Illán, Eva (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Esteban-Fabró, Roger (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Díaz-Gay, Marcos (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Lozano, Juan José (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ; Castells, Antoni (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Llovet, Josep Maria (Icahn School of Medicine at Mount Sinai (Nova York, Estats Units d'Amèrica). Tisch Cancer Institute) ; Castellví-Bel, Sergi (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Camps, Jordi (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia)
Somatic copy number alterations (CNAs) are a hallmark of cancer, but their role in tumorigenesis and clinical relevance remain largely unclear. Here, we developed CNApp, a web-based tool that allows a comprehensive exploration of CNAs by using purity-corrected segmented data from multiple genomic platforms. [...]
2020 - 10.7554/eLife.50267
eLife, Vol. 9 (january 2020)  
5.
26 p, 9.8 MB Presenilin/γ-secretase-dependent epha3 processing mediates axon elongation through non-muscle myosin IIA / Javier, Miriam (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Marco, Sergi (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Rocandio, Daniel (Institut de Recerca Biomèdica de Lleida) ; Pons Vizcarra, Maria (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Janes, Peter W. (Tumour Targeting Program. Olivia Newton-John Cancer Research Institute) ; Lackmann, Martin (Department of Biochemistry and Molecular Biology. Monash University) ; Egea, Joaquim (Institut de Recerca Biomèdica de Lleida) ; Saura Antolín, Carlos A. (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
EphA/ephrin signaling regulates axon growth and guidance of neurons, but whether this process occurs also independently of ephrins is unclear. We show that presenilin-1 (PS1)/γ-secretase is required for axon growth in the developing mouse brain. [...]
2019 - 10.7554/eLife.43646
eLife, Vol. 8 (october 2019) , p. e43646  
6.
15 p, 1.8 MB C-mannosylation supports folding and enhances stability of thrombospondin repeats / Shcherbakova, Aleksandra (Medizinische Hochschule Hannover. Institut für Klinische Biochemie) ; Preller, Matthias (Medizinische Hochschule Hannover. Institut für Biophysikalische Chemie) ; Taft, Manuel H. (Medizinische Hochschule Hannover. Institut für Biophysikalische Chemie) ; Pujols, Jordi (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Ventura, Salvador (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Tiemann, Birgit (Medizinische Hochschule Hannover. Institut für Klinische Biochemie) ; Buettner, Falk F.R. (Medizinische Hochschule Hannover. Institut für Klinische Biochemie) ; Bakker, Hans (Medizinische Hochschule Hannover. Institut für Klinische Biochemie)
Previous studies demonstrated importance of C-mannosylation for efficient protein secretion. To study its impact on protein folding and stability, we analyzed both C-mannosylated and non-C-mannosylated thrombospondin type 1 repeats (TSRs) of netrin receptor UNC-5. [...]
2019 - 10.7554/eLife.52978
eLife, Vol. 8 (Dec. 2019) , art. e52978  
7.
36 p, 10.5 MB Defective AMH signaling disrupts GnRH neuron development and function and contributes to hypogonadotropic hypogonadism / Malone, Samuel Andrew (Jean-Pierre Aubert Research Center) ; Papadakis, Georgios E. (Lausanne University Hospital. Service of Endocrinology, Diabetology and Metabolism) ; Messina, Andrea (Lausanne University Hospital. Service of Endocrinology, Diabetology and Metabolism) ; Mimouni, Nour El Houda (Jean-Pierre Aubert Research Center) ; Trova, Sara (Jean-Pierre Aubert Research Center) ; Imbernon, Monica (Jean-Pierre Aubert Research Center) ; Allet, Cecile (Jean-Pierre Aubert Research Center) ; Cimino, Irene (Jean-Pierre Aubert Research Center) ; Acierno, James (Lausanne University Hospital. Service of Endocrinology, Diabetology and Metabolism) ; Cassatella, Daniele (Lausanne University Hospital. Service of Endocrinology, Diabetology and Metabolism) ; Xu, Cheng (Lausanne University Hospital. Service of Endocrinology, Diabetology and Metabolism) ; Quinton, Richard (University of Newcastle-upon-Tyne. Institute of Genetic Medicine) ; Szinnai, Gabor (University of Basel Children's Hospital. Pediatric Endocrinology and Diabetology) ; Pigny, Pascal (Centre de Biologie Pathologie Génétique. Service Hormonologie Métabolisme Nutrition Oncologie) ; Alonso Cotchico, Lur (Universitat Autònoma de Barcelona. Departament de Química) ; Masgrau, Laura (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Maréchal, Jean-Didier (Universitat Autònoma de Barcelona. Departament de Química) ; Prevot, V. (Jean-Pierre Aubert Research Center) ; Pitteloud, Nelly (Lausanne University Hospital. Service of Endocrinology, Diabetology and Metabolism) ; Giacobini, Polo (Jean-Pierre Aubert Research Center)
Congenital hypogonadotropic hypogonadism (CHH) is a condition characterized by absent puberty and infertility due to gonadotropin releasing hormone (GnRH) deficiency, which is often associated with anosmia (Kallmann syndrome, KS). [...]
2019 - 10.7554/eLife.47198
eLife, Vol. 8 (2019) , art. e47198  
8.
19 p, 5.8 MB Giant extinct caiman breaks constraint on the axial skeleton of extant crocodylians / Scheyer, Torsten M. (University of Zurich. Paläontologisches Institut und Museum) ; Hutchinson, John R. (University of London. Royal Veterinary College (Hatfield, Regne Unit)) ; Delfino, Massimo (Institut Català de Paleontologia Miquel Crusafont) ; Strauss, Olivier (University of Zurich. Paläontologisches Institut und Museum) ; Carrillo-Briceño,Jorge D. (University of Zurich. Paläontologisches Institut und Museum) ; Sánchez, Rodolfo (Museo Paleontológico de Urumaco (Urumaco, Veneçuela)) ; Sánchez-Villagra, Marcelo R. (University of Zurich. Paläontologisches Institut und Museum)
The number of precaudal vertebrae in all extant crocodylians is remarkably conservative, with nine cervicals, 15 dorsals and two sacrals, a pattern present also in their closest extinct relatives. The consistent vertebral count indicates a tight control of axial patterning by Hox genes during development. [...]
2019 - 10.7554/eLife.49972
eLife, 2019, art. e49972
2 documents
9.
26 p, 4.7 MB Defined neuronal populations drive fatal phenotype in a mouse model of leigh syndrome / Bolea Tomás, Irene (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Gella, Alejandro (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Sanz, Elisenda (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Prada Dacasa, Patricia (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Menardy, Fabien (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Bard, Angela M. (Seattle Children's Research Institute) ; Machuca Márquez, Pablo (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Eraso-Pichot, Abel (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Mòdol Caballero, Guillem (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Navarro, Xavier (Xavier) (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Kalume, Frank (Department of Pharmacology. University of Washington) ; Quintana, Albert (Universitat Autònoma de Barcelona. Institut de Neurociències)
Mitochondrial deficits in energy production cause untreatable and fatal pathologies known as mitochondrial disease (MD). Central nervous system affectation is critical in Leigh Syndrome (LS), a common MD presentation, leading to motor and respiratory deficits, seizures and premature death. [...]
2019 - 10.7554/eLife.47163
eLife, Vol. 8 (august 2019) , p. e47163  
10.
23 p, 1.8 MB Species-specific modulation of food-search behavior by respiration and chemosensation in Drosophila larvae / Kim, Daeyeon (Universitat Pompeu Fabra) ; Alvarez, Mar (Institut Català de Nanociència i Nanotecnologia) ; Lechuga, Laura (Institut Català de Nanociència i Nanotecnologia) ; Louis, Matthieu (University of California)
Animals explore their environment to encounter suitable food resources. Despite its vital importance, this behavior puts individuals at risk by consuming limited internal energy during locomotion. We have developed a novel assay to investigate how food-search behavior is organized in Drosophila melanogaster larvae dwelling in hydrogels mimicking their natural habitat. [...]
2017 - 10.7554/eLife.27057
eLife, Vol. 6 (September 2017) , art. e27057  

Dipòsit Digital de Documents de la UAB : 14 registres trobats   1 - 10següent  anar al registre:
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