22 p, 2.6 MB
Clinical Features of Gastric Signet Ring Cell Cancer : Results from a Systematic Review and Meta-Analysis Dal Cero, Mariagiulia (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Bencivenga, Maria (Borgo Trento Hospital) ;
Liu, Drolaiz H. W. (Kepler University Hospital and Johannes Kepler University) ;
Sacco, Michele (Borgo Trento Hospital) ;
Alloggio, Mariella (Borgo Trento Hospital) ;
Kerckhoffs, Kelly G. P. (VieCuri Medical Centre) ;
Filippini, Federica (Borgo Trento Hospital) ;
Saragoni, Luca (Morgagni-Pierantoni Hospital) ;
Iglesias, Mar (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Tomezzoli, Anna (Verona University Hospital) ;
Carneiro, Fátima (Centro Hospitalar Universitário São João (Porto, Portugal)) ;
Grabsch, Heike I. (University of Leeds) ;
Verlato, Giuseppe (University of Verona) ;
Torroni, Lorena (University of Verona) ;
Piessen, Guillaume (Lille University Hospital) ;
Pera Román, Manuel (Institut Hospital del Mar d'Investigacions Mèdiques) ;
de Manzoni, Giovanni (Borgo Trento Hospital) ;
Universitat Autònoma de Barcelona The clinical behaviour of signet ring cell histology in gastric cancer has long been a subject of controversy. Recent years have underscored the pressing issue of a lack of a standardised definition for signet ring cell histology, leading to its often-ambiguous placement within broader categories associated with poor prognosis. [...]
10.3390/cancers15215191
Cancers Vol. 15 (october 2023)
16 p, 1.6 MB
Second-line treatment in advanced gastric cancer : Data from the Spanish AGAMENON registry Cotes Sanchís, Almudena (Hospital General Universitario de Elda) ;
Gallego Plazas, Javier (Hospital General Universitario de Elche) ;
Hernandez, Raquel (Hospital Universitario de Canarias (La Laguna)) ;
Arrazubi, Virginia (Complejo Hospitalario de Navarra) ;
Custodio, Ana (Hospital Universitario La Paz (Madrid)) ;
Cano, Juana María (Hospital General Universitario de Ciudad Real) ;
Aguado, Gema (Hospital General Universitario Gregorio Marañón) ;
Macias Declara, Ismael (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
López-López, Carlos A. (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ;
López, Flora (Hospital Universitario 12 de Octubre (Madrid)) ;
Visa, Laura (Hospital Universitario El Mar) ;
Garrido, Marcelo (Pontificia Universidad Católica de Chile) ;
Martínez Lago, Nieves (Complejo Hospitalario Universitario de A Coruña) ;
Fernández Montes, Ana (Complexo Hospitalario Universitario de Ourense) ;
Limón, María Luisa (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Azkárate, Aitor (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ;
Pimentel, Paola (Hospital General Universitario Santa Lucía (Cartagena, Múrcia)) ;
Reguera, Pablo (Hospital Universitario Ramón y Cajal (Madrid)) ;
Ramchandani, Avinash (Hospital Universitario Insular de Gran Canaria) ;
Cacho Lavin, Diego (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ;
Martín Carnicero, Alfonso (Hospital San Pedro de Alcántara) ;
Granja, Mónica (Hospital Universitario Clínico San Carlos (Madrid)) ;
Martín-Richard, Marta (Institut d'Investigació Biomèdica Sant Pau) ;
Hernández Pérez, Carolina (Hospital Universitario Nuestra Señora de Candelaria (Santa Cruz de Tenerife)) ;
Hurtado-Nuño, Alicia (Hospital Universitario Fundación Alcorcón) ;
Serra, Olbia (Institut Català d'Oncologia) ;
Buxo, Elvira (Hospital Universitari Vall d'Hebron) ;
Vidal Tocino, Rosario (Complejo Asistencial Universitario de Salamanca) ;
Jimenez-Fonseca, Paula (Hospital Universitario Central de Asturias) ;
Carmona-Bayonas, Alberto (Hospital General Universitario Morales Meseguer (Múrcia)) ;
Universitat Autònoma de Barcelona Second-line treatments boost overall survival in advanced gastric cancer (AGC). However, there is a paucity of information as to patterns of use and the results achieved in actual clinical practice. [...]
10.1371/journal.pone.0235848
PloS one Vol. 15 Núm. 7 July (july 2020) , p. e0235848
9 p, 740.0 KB
SEOM clinical guideline for the diagnosis and treatment of gastric cancer (GC) and gastroesophageal junction adenocarcinoma (GEJA) (2019) Martín-Richard, Marta (Institut d'Investigació Biomèdica Sant Pau) ;
Carmona-Bayonas, Alberto (Hospital General Universitario Morales Meseguer (Múrcia)) ;
Custodio, A.B. (Centro de Investigación Biomédica en Red de Cáncer) ;
Gallego, J. (Hospital General Universitario de Elche) ;
Jiménez-Fonseca, P. (Hospital Universitario Central de Asturias) ;
Reina, J.J. (Hospital Universitario Virgen Macarena (Sevilla, Andalusia)) ;
Richart, P. (Hospital Universitari i Politècnic La Fe (València)) ;
Rivera, F. (Hospital Universitario Marqués de Valdecilla (Santander, Cantabria)) ;
Alsina, M. (Hospital Universitari Vall d'Hebron) ;
Sastre Valera, Javier (Hospital Clínico San Carlos (Madrid)) ;
Universitat Autònoma de Barcelona Gastric cancer (GC) is the fifth most common cancer worldwide with a varied geographic distribution and an aggressive behavior. In Spain, it represents the sixth cause of cancer death. In Western countries, the incidence is decreasing slightly, with an increase in gastroesophageal junction adenocarcinoma (GEJA), a different entity that we separate specifically in the guideline. [...]
10.1007/s12094-019-02259-9
Clinical & Translational Oncology Vol. 22 Núm. 2 (january 2020) , p. 236-244
13 p, 4.5 MB
Effect of Perioperative Blood Transfusions and Infectious Complications on Inflammatory Activation and Long-Term Survival Following Gastric Cancer Resection Puértolas, Noelia (Hospital Universitari de Bellvitge) ;
Osorio, Javier (Hospital Universitari de Bellvitge) ;
Jericó, Carlos (Hospital de Sant Joan Despí Moisès Broggi) ;
Miranda, Coro (Hospital Universitario de Navarra) ;
Santamaría, Maite (Hospital Arnau de Vilanova (Lleida, Catalunya)) ;
Artigau, Eva (Hospital Universitari de Girona Doctor Josep Trueta) ;
Galofré, Gonzalo (Hospital de Sant Joan Despí Moisès Broggi) ;
Garsot, Elisenda (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Luna, Alexis (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Aldeano, Aurora (Hospital General de Granollers) ;
Olona, Carles (Hospital Universitari de Tarragona) ;
Molinas, Joan (Hospital Universitari de Vic) ;
Pulido, Laura (Hospital de Mataró. Consorci Sanitari del Maresme) ;
Gimeno, Marta (Hospital del Mar (Barcelona, Catalunya)) ;
Pera Román, Manuel (Hospital del Mar (Barcelona, Catalunya)) ;
Universitat Autònoma de Barcelona Both postoperative complications and perioperative blood transfusions have been separately related to worse prognosis after gastrectomy for patients with gastric cancer. This multicenter cohort study aims to evaluate their synergic effect on inflammatory activation and prognosis. [...]
10.3390/cancers15010144
Cancers Vol. 15 (december 2022)
12 p, 1.5 MB
External validity of docetaxel triplet trials in advanced gastric cancer : are there patients who still benefit? Jimenez-Fonseca, Paula (Hospital Universitario Central de Asturias. ISPA) ;
Carmona-Bayonas, Alberto (Fundación Séneca (04515/GERM/06)) ;
Martínez de Castro, Eva (Instituto de Investigación Sanitaria Valdecilla (Santander, Cantàbria)) ;
Custodio, Ana (Hospital Universitario La Paz (Madrid)) ;
Pericay, Carles (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Hernandez-San Gil, Raquel (Hospital Universitario de Canarias (La Laguna)) ;
Aguado, Gema (Hospital General Universitario Gregorio Marañón) ;
Castro Unanua, Natalia (Complejo Hospitalario de Navarra) ;
Cano, Juana María (Hospital General Universitario de Ciudad Real) ;
López López, Flora (Hospital Universitario 12 de Octubre (Madrid)) ;
Garrido Salvo, Marcelo (Pontificia Universidad Católica de Chile) ;
Fernández Montes, Ana (Complejo Hospitalario de Orense) ;
Visa, Laura (Hospital Universitario El Mar) ;
Sánchez Cánovas, Manuel (Hospital General Universitario Morales Meseguer (Múrcia)) ;
Limón, María Luisa (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Martínez Lago, Nieves (Complejo Hospitalario Universitario de A Coruña) ;
Pimentel, Paola (Hospital Santa Lucía) ;
Hurtado-Nuño, Alicia (Hospital Universitario Fundación Alcorcón) ;
Azkárate, Aitor (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ;
Longo, Federico (Hospital Universitario Ramón y Cajal (Madrid)) ;
Díez García, Marc (Hospital Universitari Vall d'Hebron) ;
Arias-Martinez, Aránzazu. (Hospital Universitario Central de Asturias) ;
Saurí Nadal, Tamara (Hospital Clínic i Provincial de Barcelona) ;
Martín Carnicero, Alfonso (Hospital San Pedro de Alcántara) ;
Mangas, Montserrat (Hospital de Galdakao (Usansolo, Biscaia)) ;
Martín-Richard, Marta (Institut d'Investigació Biomèdica Sant Pau) ;
Granja Ortega, Mónica (Hospital Universitario Clínico San Carlos (Madrid)) ;
Ramchandani, Avinash (Hospital Universitario Insular de Gran Canaria) ;
Hernández Pérez, Carolina (Hospital Universitario Nuestra Señora de Candelaria (Santa Cruz de Tenerife)) ;
Cerdà, Paula (Centro Médico Tecknon) ;
Gil-Negrete Laborda, Aitziber (Hospital de Donostia (Sant Sebastià, País Basc)) ;
Calvo, Mariona (Institut Català d'Oncologia) ;
Vidal Tocino, Rosario (Complejo Asistencial Universitario de Salamanca. IBSAL) ;
Gallego Plazas, Javier (Hospital General Universitario de Elche) Background: The purpose of our study was to develop an online calculator to estimate the effect of docetaxel triplets (DPF) in first line of advanced gastric cancer (AGC), and to assess the external validity of docetaxel trials in individual patients. [...]
10.1007/s10120-020-01116-x
Gastric Cancer Vol. 24 Núm. 2 (march 2021) , p. 445-456
17 p, 2.4 MB
Follow-Up Study Confirms the Presence of Gastric Cancer DNA Methylation Hallmarks in High-Risk Precursor Lesions Gómez Moruno, Antonio (Institut d'Investigació Biomèdica de Bellvitge) ;
Pato, Miguel L. (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Bujanda, Luis (Biodonostia Osasun Ikerketako Institutura (País Basc)) ;
Sala, Núria (Institut Català d'Oncologia) ;
Companioni, Osmel (Institut Català d'Oncologia) ;
Cosme, Ángel (Biodonostia Osasun Ikerketako Institutura (País Basc)) ;
Tufano, Martina (Institut d'Investigació Biomèdica de Bellvitge) ;
Hanly, David J. (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
García, Nadia (Institut Català d'Oncologia) ;
Sanz-Anquela, José Miguel (Hospital Universitario Príncipe de Asturias (Alcalá de Henares, Madrid)) ;
P. Gisbert, Javier (Hospital Universitario de la Princesa (Madrid)) ;
López, Consuelo (Hospital Universitario de la Princesa (Madrid)) ;
Elizalde, José Ignacio (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Cuatrecasas, Miriam (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Andreu, Victoria (Hospital de Viladecans) ;
Paules, María José (Hospital Universitari de Bellvitge) ;
Martín-Arranz, María Dolores (Instituto de Investigación Sanitaria del Hospital Universitario La Paz) ;
Ortega, Luis (Hospital Clínico San Carlos (Madrid)) ;
Poves, Elvira (Hospital Universitario Príncipe de Asturias (Alcalá de Henares, Madrid)) ;
Barrio, Jesús (Hospital Universitario Río Hortega (Valladolid)) ;
Torres, María Ángeles (Hospital Universitario Río Hortega (Valladolid)) ;
Muñoz, Guillermo (Hospital Clínico Universitario "Lozano Blesa" de Zaragoza) ;
Ferrández, Ángel (Hospital Clínico Universitario "Lozano Blesa" de Zaragoza) ;
Ramírez-Lázaro, María José (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Lario, Sergio (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
González, Carlos A. (Institut Català d'Oncologia) ;
Esteller, M (Universitat de Barcelona. Departament de Ciències Fisiològiques) ;
Berdasco, Maria (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Universitat Autònoma de Barcelona Intestinal metaplasia confers an increased risk of progression to gastric cancer. However, some intestinal metaplasia patients do not develop cancer. The development of robust molecular biomarkers to stratify patients with advanced gastric precursor lesions at risk of cancer progression will contribute to guiding programs for prevention. [...]
10.3390/cancers13112760
Cancers Vol. 13 (june 2021)
10 p, 384.2 KB
Efficacy and Safety of Trifluridine/Tipiracil Treatment in Patients With Metastatic Gastric Cancer Who Had Undergone Gastrectomy Ilson, David H. (Memorial Sloan Kettering Cancer Center (Estats Units d'Amèrica)) ;
Tabernero, Josep (Vall d'Hebron Institut d'Oncologia) ;
Prokharau, Aliaksandr (Minsk City Clinical Oncology Dispensary) ;
Arkenau, Hendrik-Tobias (University College London) ;
Ghidini, Michele (Azienda Ospedaliera di Cremona) ;
Fujitani, Kazumasa (Osaka General Medical Center) ;
Van Cutsem, Eric (University Hospitals Gasthuisberg (Leuven, Bélgica)) ;
Thuss-Patience, Peter (Charité - Universitätsmedizin Berlin) ;
Beretta, Giordano D. (Humanitas Gavazzeni) ;
Mansoor, Wasat (The Christie NHS Foundation Trust (Regne Unit)) ;
Zhavrid, Edvard (Alexandrov National Cancer Centre of Belarus) ;
Alsina, Maria (Vall d'Hebron Institut d'Oncologia) ;
George, Ben (Medical College of Wisconsin) ;
Catenacci, Daniel (University of Chicago) ;
McGuigan, Sandra (Taiho Oncology Inc) ;
Makris, Lukas (Stathmi Inc) ;
Doi, Toshihiko (National Cancer Center Hospital East (Japó)) ;
Shitara, Kohei (National Cancer Center Hospital East (Japó)) ;
Universitat Autònoma de Barcelona This subgroup analysis of a randomized clinical trial compares trifluridine/tipiracil treatment with placebo for progression-free and overall survival among patients with previously treated metastatic gastric or gastroesophageal junction cancer who had or had not undergone gastrectomy. [...]
10.1001/jamaoncol.2019.3531
JAMA Oncology Vol. 6 (october 2019)
10 p, 1008.8 KB
Preoperative neutrophil-to-lymphocyte ratio behaves as an independent prognostic factor even in patients with postoperative complications after curative resection for gastric cancer Tur-Martínez, Jaume (Universitat Autònoma de Barcelona. Departament de Cirurgia) ;
Osorio, Javier (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) ;
Pérez-Romero, Noelia (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) ;
Puértolas-Rico, Noelia (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) ;
Pera Román, Manuel (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Delgado, Salvadora (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) ;
Rodríguez-Santiago, Joaquín (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) Purpose The aim of this study was to determine if the prognostic value of the preoperative neutrophil-to-lymphocyte ratio (NLR) could be modified by the presence of postoperative complications (POC) and their severity in patients with gastric adenocarcinoma resected with curative intent. [...]
10.1007/s00423-022-02432-9
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