Evaluation of the immunological profile of antibody-functionalized metal-filled single-walled carbon nanocapsules for targeted radiotherapy - Resultats de la cerca

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Evaluation of the immunological profile of antibody-functionalized metal-filled single-walled carbon nanocapsules for targeted radiotherapy / Pérez Ruiz De Garibay, Aritz (Centre National de la Recherche Scientifique (França)) ; Spinato, Cinzia (Centre National de la Recherche Scientifique (França)) ; Klippstein, Rebecca (King's College London. Institute of Pharmaceutical Science) ; Bourgognon, Maxime (King's College London. Institute of Pharmaceutical Science) ; Martincic, Markus (Institut de Ciència de Materials de Barcelona) ; Pach, Elzbieta (Institut Català de Nanociència i Nanotecnologia) ; Ballesteros, Belén (Institut Català de Nanociència i Nanotecnologia) ; Ménard-Moyon, Cécilia (Centre National de la Recherche Scientifique (França)) ; Al-Jamal, Khuloud T. (King's College London. Institute of Pharmaceutical Science) ; Tobias, Gerard (Institut de Ciència de Materials de Barcelona) ; Bianco, Alberto (Centre National de la Recherche Scientifique (França))
This study investigates the immune responses induced by metal-filled single-walled carbon nanotubes (SWCNT) under in vitro, ex vivo and in vivo settings. Either empty amino-functionalized CNTs [SWCNT-NH 2 (1)] or samarium chloride-filled amino-functionalized CNTs with [SmCl 3 @SWCNT-mAb (3)] or without [SmCl 3 @SWCNT-NH 2 (2)] Cetuximab functionalization were tested. [...]
2017 - DOI (Digital Object Identifier)

10.1038/srep42605
Scientific reports, Vol. 7 (February 2017) , art. 42605

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