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24 p, 1.7 MB Integration and Validation of the GenomeScale Metabolic Models of Pichia pastoris : a Comprehensive Update of Protein Glycosylation Pathways, Lipid and Energy Metabolism / Tomàs Gamisans, Màrius (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental) ; Ferrer i Alegre, Pau (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental) ; Albiol i Sala, Joan (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental)
Motivation: Genome-scale metabolic models (GEMs) are tools that allow predicting a phenotype from a genotype under certain environmental conditions. GEMs have been developed in the last ten years for a broad range of organisms, and are used for multiple purposes such as discovering new properties of metabolic networks, predicting new targets for metabolic engineering, as well as optimizing the cultivation conditions for biochemicals or recombinant protein production. [...]
2016 - 10.1371/journal.pone.0148031
PloS one, Vol. 11 Núm. 1 (January 2016) , p. 1-24  

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