Lack of synergistic effect of resveratrol and sigma-1 receptor agonist (PRE-084) in SOD1 G93A ALS mice overlapping effects or limited therapeutic opportunity? - Search Results

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Lack of synergistic effect of resveratrol and sigma-1 receptor agonist (PRE-084) in SOD1 G93A ALS mice : overlapping effects or limited therapeutic opportunity? / Mancuso, Renzo (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Del Valle, Jaume (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Morell, Marta (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Pallàs, Mercè (Universitat de Barcelona. Institut de Biomedicina) ; Osta, Rosario (Universidad de Zaragoza) ; Navarro, X. (Xavier) (Xavier) (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia
Amyotrophic lateral sclerosis (ALS) is an adult onset neurodegenerative disease characterized by the loss of motoneurons (MNs) in the spinal cord, brainstem and motor cortex, causing progressive paralysis and death. [...]
2014 - DOI (Digital Object Identifier)

10.1186/1750-1172-9-78
Orphanet Journal of Rare Diseases, Vol. 9 (May 2014) , art. 78

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