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12 p, 853.4 KB Lipid droplet biogenesis induced by stress involves triacylglycerol synthesis that depends on group VIA phospholipase A2 / Gubern Burset, Albert (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Barceló Torns, Miquel (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Casas, Javier (Consejo Superior de Investigaciones Científicas. Instituto de Biología y Genética Molecular) ; Barneda, David (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Masgrau Juanola, Roser (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Picatoste Ramón, Fernando (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Balsinde, Jesús (Consejo Superior de Investigaciones Científicas. Instituto de Biología y Genética Molecular) ; Balboa María A. (Consejo Superior de Investigaciones Científicas. Instituto de Biología y Genética Molecular) ; Claro Izaguirre, Enrique (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular)
This work investigates the metabolic origin of triacylglycerol (TAG) formed during lipid droplet (LD) biogenesis induced by stress. Cytotoxic inhibitors of fatty acid synthase induced TAG synthesis and LD biogenesis in CHO-K1 cells, in the absence of external sources of fatty acids. [...]
2009 - 10.1074/jbc.M806173200
The Journal of biological chemistry, Vol. 284, Num. 9 (2009) , p. 5697-56708  

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