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Resultats globals: 16 registres trobats en 0.03 segons.
Articles, 9 registres trobats
Documents de recerca, 1 registres trobats
Fons personals i institucionals, 6 registres trobats
Articles 9 registres trobats  
1.
15 p, 655.6 KB Split First Dose Administration of Intravenous Daratumumab for the Treatment of Multiple Myeloma (MM) : Clinical and Population Pharmacokinetic Analyses / Xu, X. S. (Janssen Research & Development. LLC) ; Moreau, Philippe (CHU de Nantes) ; Usmani, S. Z. (Levine Cancer Institute/Atrium Health) ; Lonial, S. (Winship Cancer Institute. Emory University) ; Jakubowiak, A. (University of Chicago Medical Center) ; Oriol, Albert (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Krishnan, A. (City of Hope) ; Bladé Creixenti, Juan (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Luo, M. (Janssen Research & Development. LLC) ; Sun, Y. N. (Janssen Research & Development. LLC) ; Zhou, H. (Janssen Research & Development. LLC) ; Nnane, I. (Janssen Research & Development. LLC) ; Deraedt, W. (Janssen Research & Development) ; Qi, M. (Janssen Research & Development. LLC) ; Ukropec, J. (Janssen Scientific Affairs. LLC) ; Clemens, P. L. (Janssen Research & Development. LLC) ; Universitat Autònoma de Barcelona
Introduction: Daratumumab, a human immunoglobulin Gκ monoclonal antibody targeting CD38, is approved as monotherapy and in combination with standard-of-care regimens for multiple myeloma. In clinical studies, the median durations of the first, second, and subsequent intravenous infusions of daratumumab were 7. [...]
2020 - 10.1007/s12325-020-01247-8
Advances in Therapy, Vol. 37 Núm. 4 (january 2020) , p. 1464-1478  
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2.
11 p, 1.5 MB Comparison of flow-FISH and MM-qPCR telomere length assessment techniques for the screening of telomeropathies / Ferreira, M. S. V. (University Hospital Aachen (Alemanya)) ; Kirschner, M. (University Hospital Aachen (Alemanya)) ; Halfmeyer, I. (University Hospital Aachen (Alemanya)) ; Estrada Barreras, Natalia (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Xicoy, Blanca (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Isfort, S. (University Hospital Aachen (Alemanya)) ; Vieri, M. (University Hospital Aachen (Alemanya)) ; Zamora, Lurdes (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Abels, A. (University Hospital Aachen (Alemanya)) ; Bouillon, A. S. (University Hospital Aachen (Alemanya)) ; Begemann, M. (Institute of Human Genetics. Medical Faculty. RWTH Aachen University) ; Schemionek, M. (University Hospital Aachen (Alemanya)) ; Maurer, A. (University Hospital Aachen (Alemanya)) ; Koschmieder, Steffen (University Hospital Aachen (Alemanya)) ; Wilop, S. (University Hospital Aachen (Alemanya)) ; Panse, J. (University Hospital Aachen (Alemanya)) ; Brümmendorf, Tim H (University Hospital Aachen (Alemanya)) ; Beier, F. (University Hospital Aachen (Alemanya)) ; Universitat Autònoma de Barcelona
Assessment of telomere length (TL) in peripheral blood leukocytes is part of the diagnostic algorithm applied to patients with acquired bone marrow failure syndromes (BMFSs) and dyskeratosis congenita (DKC). [...]
2020 - 10.1111/nyas.14248
Annals of the New York Academy of Sciences, Vol. 1466 Núm. 1 (2020) , p. 93-103  
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3.
13 p, 8.3 MB Understanding the molecular mechanism of the Ala-versus-Gly concept controlling the pProduct specificity in reactions catalyzed by lipoxygenases : a combined molecular dynamics and QM/MM study of coral 8R-lipoxygenase / Saura Martínez, Patricia (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Suardíaz, Reynier (King's College London. Department of Chemistry) ; Masgrau, Laura (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; González-Lafont, Àngels (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Rosta, Edina (King's College London. Department of Chemistry) ; Lluch López, Josep Maria (Universitat Autònoma de Barcelona. Departament de Química)
Lipoxygenases (LOXs) are a family of enzymes that catalyze the highly specific hydroperoxidation of polyunsaturated fatty acids, such as arachidonic acid. Different stereo- or/and regioisomer hydroperoxidation products lead later to different metabolites that exert opposite physiological effects in the animal body and play a central role in inflammatory processes. [...]
2017 - 10.1021/acscatal.7b00842
ACS catalysis, Vol. 7, issue 7 (July 2017) , p. 4854-4866  
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4.
12 p, 1.4 MB Unraveling how the Gly526Ser mutation arrests prostaglandin formation from arachidonic acid catalyzed by cyclooxygenase-2 : A combined molecular dynamics and QM/MM study / Suñer Rubio, Adrián (Universitat Autònoma de Barcelona. Departament de Química) ; Cebrián Prats, Anna (Universitat Autònoma de Barcelona. Departament de Química) ; González-Lafont, Àngels (Universitat Autònoma de Barcelona. Departament de Química) ; Lluch López, Josep Maria (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí")
Cyclooxygenases (COXs) are the enzymes responsible for the biosynthesis of prostaglandins, eicosanoids that play a major role in many physiological processes. Particularly, prostaglandins are known to trigger inflammation, and COX-2, the enzyme isoform associated with this inflammatory response, catalyzes the cyclooxidation of arachidonic acid, leading to prostaglandin G2. [...]
2019 - 10.1039/c9ra08860a
RSC advances, Vol. 10, issue 2 (2019) , p. 986-997  
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5.
19 p, 2.2 MB Comparing hydrolysis and transglycosylation reactions catalyzed by Thermus thermophilus β-glycosidase. A combined MD and QM/MM study / Romero Tellez, Sonia (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Lluch López, Josep Maria (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; González-Lafont, Àngels (Universitat Autònoma de Barcelona. Departament de Química) ; Masgrau, Laura (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí")
The synthesis of oligosaccharides and other carbohydrate derivatives is of relevance for the advancement of glycosciences both at the fundamental and applied level. For many years, glycosyl hydrolases (GHs) have been explored to catalyze the synthesis of glycosidic bonds. [...]
2019 - 10.3389/fchem.2019.00200
Frontiers in chemistry, Vol. 7 (April 2019) , art. 200  
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6.
15 p, 9.5 MB Addressing the Environment Electrostatic Effect on Ballistic Electron Transport in Large Systems : A QM/MM-NEGF Approach / Feliciano, Gustavo T. (Universidade Estadual Paulista (Brasil)) ; Sanz Navarro, Carlos (Institut Català de Nanociència i Nanotecnologia) ; Coutinho-Neto, Mauricio Domingues (Universidade Federal do ABC (Brasil)) ; Ordejon, Pablo (Institut Català de Nanociència i Nanotecnologia) ; Scheicher, Ralph H. (Uppsala University) ; Reily Rocha, Alexandre (Universidade Estadual Paulista (Brasil))
The effects of the environment in nanoscopic materials can play a crucial role in device design. Particularly in biosensors, where the system is usually embedded in a solution, water and ions have to be taken into consideration in atomistic simulations of electronic transport for a realistic description of the system. [...]
2018 - 10.1021/acs.jpcb.7b03475
Journal of physical chemistry B, Vol. 122, Núm. 2 (January 2018) , p. 485-492  
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7.
30 p, 1.5 MB QM/MM Molecular Dynamics Studies of Metal Binding Proteins / Vidossich, Pietro (Universitat Autònoma de Barcelona. Departament de Química) ; Magistrato, Alessandra (CNR-IOM-Democritos National Simulation Center)
Mixed quantum-classical (quantum mechanical/molecular mechanical (QM/MM)) simulations have strongly contributed to providing insights into the understanding of several structural and mechanistic aspects of biological molecules. [...]
2014 - 10.3390/biom4030616
Biomolecules, Vol. 4 (july 2014) , p. 616-645  
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8.
1 p, 162.2 KB MM / Harris, Marguerite
1969
Wormwood Review, Vol. 9 Núm. 2, Issue 34 (1969) , p. 10  
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9.
2 p, 335.8 KB Codex MM (11) / Beaudoin, Kenneth L.
1966
Wormwood Review, Vol. 6 Núm. 2, Issue 22 (1966) , p. 29-30  
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Documents de recerca 1 registres trobats  
1.
133 p, 8.6 MB Molecular modelling of transition metal complexes with QM/MM methods : structure and reactivity / Ujaque Pérez, Gregori (Universitat Autònoma de Barcelona. Departament de Química) ; Lledós, Agustí, (Lledós i Falcó), dir. (Universitat Autònoma de Barcelona. Departament de Química) ; Maseras Cuní, Feliu, dir. (Universitat Autònoma de Barcelona. Departament de Química)
El trabajo presentado en esta tesis consiste principalmente en la aplicación del método IMOMM (un método que combina la mecánica cuántica y la mecánica molecular) al estudio de sistemas químicos donde se ven involucrados complejos de metales de transición. [...]
Bellaterra : Universitat Autònoma de Barcelona, 2008
2 documents
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Fons personals i institucionals 6 registres trobats  
1.
18 p, 9.1 MB Función de Gala en Honor de SS. MM. los Reyes de Thailandia / Albéniz i Pascual, Isaac 1860-1909 ; Alfonso, Juan ; Bretón y Hernández, Tomás 1850-1923 ; Chapí Lorente, Ruperto 1851-1909 ; Coma Vicens, Joan ; Granados y Campiña, Enric 1867-1916 ; Magrinyà, Joan ; Morera i Viura, Enric ; Turina Pérez, Joaquín ; Xancó, Ernest ; Gran Teatre del Liceu. Ballet ; Ballets de Catalunya ; Orquestra del Gran Teatre del Liceu ; Societat del Gran Teatre del Liceu
1960  
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2.
3 p, 553.4 KB Tournée artistique de la celebre Mm. Marie Montbazón : primavera de 1894 : ocho únicas representaciones / Montbazon, Marie ; Societat del Gran Teatre del Liceu
Barcelona : 1894  
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3.
9 p, 1.7 MB Madama Butterfly : función de gala en honor de SS.MM. Don Alfonso XIII y Doña Victoria Eugenia (martes, 27 de maig de 1930) / Puccini, Giacomo 1858-1924 ; Societat del Gran Teatre del Liceu
Barcelona : 1930  
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4.
5 p, 1.4 MB Función de Gala en honor y asistencia de SS. MM. Don Alfonso y Doña Victoria Eugenia / Coates, Albert ; Rimskij-Korsakov, Nicolaj 1844-1908 ; Societat del Gran Teatre del Liceu
Barcelona : 1927 (Temporada 1927-1928)  
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5.
8 p, 1.5 MB Función regia en honor de SS. MM. Don Alfonso XIII y Doña Victoria Eugenia / Musorgski, Modest Petrovitx 1839-1881 ; Steimann, Michel ; Societat del Gran Teatre del Liceu
Barcelona : 1929  
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6.
3 p, 689.0 KB Extraordinario concierto por la Orquestra Pau Casals en honor de SS. MM. Don Alfonso y Doña Victoria Eugenia / Casals, Pau 1876-1973 ; Orquestra Pau Casals ; Societat del Gran Teatre del Liceu
Barcelona : 1926  
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