Pàgina inicial > Resultats de la cerca: Statins and selective inhibition of Rho kinase protect small conductance calcium-activated potassium channel function (KCa2.3) in cerebral arteries
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11 p, 695.0 KB Statins and selective inhibition of Rho kinase protect small conductance calcium-activated potassium channel function (KCa2.3) in cerebral arteries / McNeish, Alister J. (University of Reading. Reading School of Pharmacy) ; Jiménez Altayó, Francesc (University of Oxford. Department of Pharmacology) ; Cottrell, Graeme S. (University of Bath. Department pf Pharmacy and Pharmacology) ; Garland, Christopher J. (University of Oxford. Department of Pharmacology)
Background: In rat middle cerebral and mesenteric arteries the KCa2. 3 component of endothelium-dependent hyperpolarization (EDH) is lost following stimulation of thromboxane (TP) receptors, an effect that may contribute to the endothelial dysfunction associated with cardiovascular disease. [...]
2012 - 10.1371/journal.pone.0046735
PloS one, Vol. 7, Issue 10 (October 2012) , p. e46735  
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