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Dipòsit Digital de Documents de la UAB 77 registres trobats  1 - 10següentfinal  anar al registre: La cerca s'ha fet en 0.01 segons. 
1.
15 p, 2.1 MB Proteoliposomal formulations of an HIV-1 gp41-based miniprotein elicit a lipid-dependent immunodominant response overlapping the 2F5 binding motif / Molinos-Albert, Luis Manuel (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Bilbao, Eneritz (Universidad del País Vasco (UPV/EHU). Department of Biochemistry and Molecular Biology) ; Agulló, Luis (Universitat de Vic. Departament de Biociències) ; Marfil, Silvia (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; García, Elisabet (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Rodríguez de la Concepción, Maria Luisa (Institut Germans Trias i Pujol) ; Izquierdo-Useros, Nuria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Vilaplana, Cristina (Institut Germans Trias i Pujol. Unitat de Tuberculosi Experimental) ; Nieto-Garai, Jon A. (Universidad del País Vasco (UPV/EHU). Department of Biochemistry and Molecular Biology) ; Contreras, F. Xabier (Universidad del País Vasco (UPV/EHU). Department of Biochemistry and Molecular Biology) ; Floor, Martin (Universitat de Vic. Departament de Biociències) ; Cardona, Pere J. (Institut Germans Trias i Pujol. Unitat de Tuberculosi Experimental) ; Martinez-Picado, Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Clotet, Bonaventura (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Villà-Freixa, Jordi (Universitat de Vic. Departament de Biociències) ; Lorizate, Maier (Universidad del País Vasco (UPV/EHU). Department of Biochemistry and Molecular Biology) ; Carrillo, Jorge (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Blanco, Julià (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa)
The HIV-1 gp41 Membrane Proximal External Region (MPER) is recognized by broadly neutralizing antibodies and represents a promising vaccine target. However, MPER immunogenicity and antibody activity are influenced by membrane lipids. [...]
2017 - 10.1038/srep40800
Scientific Reports, gener 2017, p. 1-15  
2.
126 p, 7.5 MB Alteraciones de los linfocitos T en pacientes con trastorno por uso de alcohol / Zuluaga Blanco, Yenny Paola, autor. ; Muga Bustamante, Roberto, supervisor acadèmic. ; Tor Aguilera, J., supervisor acadèmic. ; Universitat Autònoma de Barcelona. Departament de Medicina.
El Trastorno por Uso de Alcohol (TUA) es una enfermedad que puede cursar con múltiples complicaciones. El sistema inmunológico se ve comprometido por el abuso de alcohol, hecho que predispone al desarrollo de múltiples enfermedades, entre las que destacan las infecciosas. [...]
Alcohol Use Disorder (AUD) is a disease with multiple associated complications. The immune system can be compromised by alcohol abuse and alterations of the innate and adaptive immunity may predispose to the development of infections. [...]

[Barcelona] : Universitat Autònoma de Barcelona, 2018.  
3.
5 p, 81.7 KB Bases Moleculars de la Transducció de Senyal i el Càncer [42893] / Grup mort cel.lular, senescència i super, Victor J. Yuste Mateos ; Gómez Trias, Néstor ; Lizcano de Vega, José Miguel ; Lopez Blanco, Jose Manuel ; Yuste Mateos, Victor Jose ; Bayascas Ramirez, Jose Ramon ; Bassols Serra, Anna ; Universitat Autònoma de Barcelona. Facultat de Biociències
Providing advanced training on the molecular mechanisms involved in signal transduction pathways and in the control of cell proliferation, and how these mechanisms are altered in the cancer cell. Reviewing and updating key concepts of the field Defining our current knowledge on the field, as well as identifying critical issues to be investigated.
1 Providing advanced training on the molecular mechanisms involved in signal transduction pathways and in the control of cell proliferation, and how these mechanisms are altered in the cancer cell. Reviewing and updating key concepts of the field Defining our current knowledge on the field, as well as identifying critical issues to be investigated.

2018-19
Màster Universitari en Bioquímica, Biologia Molecular i Biomedicina [1153]
3 documents
4.
23 p, 9.1 MB MicroRNA-200, associated with metastatic breast cancer, promotes traits of mammary luminal progenitor cells / Sánchez-Cid, Lourdes (Instituto de Salud Carlos III. CIBER de Bioingeniería, Biomateriales y Nanomedicina) ; Pons, Mònica (Consell Superior d'Investigacions Científiques. Institut de Biologia Molecular (IBMB-CSIC)) ; Lozano, Juan José (Instituto de Salud Carlos III. Centro de investigación biomédica en red. Enfermedades hepáticas y digestivas (CIBER-EHD)) ; Rubio, Nuria (Institut de Química avançada de Catalunya (IQAC-CSIC)) ; Guerra-Rebollo, Marta (Institut de Química avançada de Catalunya (IQAC-CSIC)) ; Soriano, Aroa (Vall d'Hebron Institut de Recerca (VHIR)) ; Paris-Coderch, Laia (Vall d'Hebron Institut de Recerca (VHIR)) ; Segura, Miquel F. (Vall d'Hebron Institut de Recerca (VHIR)) ; Fueyo, Raquel (Consell Superior d'Investigacions Científiques. Institut de Biologia Molecular (IBMB-CSIC)) ; Arguimbau, Judit (Consell Superior d'Investigacions Científiques. Institut de Biologia Molecular (IBMB-CSIC)) ; Zodda, Erika (Universitat de Barcelona. Departament de Bioquímica i Biologia molecular) ; Bermudo, Raquel (Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS)) ; Alonso, Immaculada (Hospital Clínic de Barcelona. Departament d'Obstetrícia i Ginecologia) ; Caparrós, Xavier (Hospital Clínic de Barcelona. Departament d'Obstetrícia i Ginecologia) ; Cascante, Marta (Universitat de Barcelona. Departament de Bioquímica i Biologia molecular) ; Rafii, Arash (Weill Cornell Medical College. Education City (Ar-Rayyan, Qatar)) ; Kang, Yibin (Princeton University. Department of Molecular Biology) ; Martínez-Balbás, Marian (Consell Superior d'Investigacions Científiques. Institut de Biologia Molecular (IBMB-CSIC)) ; Weiss, Stephen J. (University of Michigan. Life Sciences Institute) ; Blanco, Jerónimo (Institut de Química avançada de Catalunya (IQAC-CSIC)) ; Muñoz, Montserrat (Hospital Clínic de Barcelona. Departament d'Oncologia) ; Fernández, Pedro L. (Universitat de Barcelona. Facultat de Medicina) ; Thomson, Timothy M. (Consell Superior d'Investigacions Científiques. Institut de Biologia Molecular (IBMB-CSIC)) ; Universitat Autònoma de Barcelona
MicroRNAs are critical regulators of gene networks in normal and abnormal biological processes. Focusing on invasive ductal breast cancer (IDC), we have found dysregulated expression in tumor samples of several microRNAs, including the miR-200 family, along progression from primary tumors to distant metastases, further reflected in higher blood levels of miR-200b and miR-7 in IDC patients with regional or distant metastases relative to patients with primary node-negative tumors. [...]
2017 - 10.18632/oncotarget.20698
Oncotarget, Vol. 8, Num. 48 (October 2017) , p. 83384-83406  
5.
8 p, 1.6 MB Combined chondroitin sulfate and glucosamine for painful knee osteoarthritis : a multicentre, randomised, double-blind, non-inferiority trial versus celecoxib / Hochberg, Marc C. (University of Maryland School of Medicine) ; Martel-Pelletier, Johanne (Centre hospitalier de l’Université de Montréal) ; Monfort, Jordi (Institut Hospital del Mar d'Investigacions Mèdiques) ; Möller, Ingrid (Institut Poal de Reumatologia) ; Castillo, Juan Ramón (Hospital Universitario Virgen del Rocío) ; Arden, Nigel (University of Oxford. Medical Science Division) ; Berenbaum, Francis (Sorbonne University) ; Blanco, Francisco J (Instituto de Investigación Biomédica de A Coruña) ; Conaghan, Philip G (Leeds Institute of Rheumatic and Musculoskeletal Medicine) ; Doménech, Gema (Universitat Autònoma de Barcelona. Facultat de Medicina) ; Henrotin, Yves (Université de Liège. Faculté de Médecine. Unité de Recherche sur l’Os et le Cartilage) ; Pap, Thomas (Universitätsklinikum Münster. Institut für Muskuloskelettale Medizin) ; Richette, Pascal (Université Paris-Diderot) ; Sawitzke, Allen (University of Utah School of Medicine) ; du Souich, Patrick (Université de Montréal. Département de pharmacologie et physiologie) ; Pelletier, Jean-Pierre (Centre de recherche du Centre hospitalier de l’Universite de Montreal)
To compare the efficacy and safety of chondroitin sulfate plus glucosamine hydrochloride (CS+GH) versus celecoxib in patients with knee osteoarthritis and severe pain. Double-blind Multicentre Osteoarthritis interVEntion trial with SYSADOA (MOVES) conducted in France, Germany, Poland and Spain evaluating treatment with CS+GH versus celecoxib in 606 patients with Kellgren and Lawrence grades 2–3 knee osteoarthritis and moderate-to-severe pain (Western Ontario and McMaster osteoarthritis index (WOMAC) score ≥301; 0–500 scale). [...]
2015 - 10.1136/annrheumdis-2014-206792
Annals of the rheumatic diseases, Vol. 75, issue 1 (Jan. 2016) , p. 37-44  
6.
12 p, 371.6 KB DNA Glycosylases Involved in Base Excision Repair May Be Associated with Cancer Risk in BRCA1 and BRCA2 Mutation Carriers / Osorio, Ana (Biomedical Network on Rare Diseases (CIBERER), Madrid, Spain) ; Milne, Roger L. (Cancer Epidemiology Centre, Cancer Council Victoria, Melbourne, Australia) ; Kuchenbaecker, Karoline (Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom) ; Vaclová, Tereza (Human Genetics Group, Spanish National Cancer Centre (CNIO), Madrid, Spain) ; Pita, Guillermo (Genotyping Unit (CeGen), Spanish National Cancer Centre (CNIO), Madrid, Spain) ; Alonso, Rosario (Genotyping Unit (CeGen), Spanish National Cancer Centre (CNIO), Madrid, Spain) ; Peterlongo, Paolo (IFOM, Fondazione Istituto FIRC di Oncologia Molecolare, Milan, Italy) ; Blanco Guillermo, Ignacio (Institut Català d'Oncologia) ; de la Hoya, Miguel (Molecular Oncology Laboratory, Hospital Clinico San Carlos, IdISSC, Madrid, Spain) ; Duran, Mercedes (Institute of Biology and Molecular Genetics, Universidad de Valladolid (IBGM-UVA), Valladolid, Spain) ; Díez, Orland (Vall d'Hebron Institut d'Oncologia) ; Ramón y Cajal, Teresa (Institut d'Investigacions Biomèdiques Sant Pau) ; Konstantopoulou, Irene (Molecular Diagnostics Laboratory IRRP, National Centre for Scientific Research Demokritos Aghia Paraskevi Attikis, Athens, Greece) ; Martínez-Bouzas, Cristina (Molecular Genetics Laboratory (Department of Biochemistry), Cruces Hospital Barakaldo, Bizkaia, Spain) ; Andrés Conejero, Raquel (Medical Oncology Service, Hospital Clínico Lozano Blesa, San Juan Bosco, Zaragoza, Spain) ; Soucy, Penny (Cancer Genomics Laboratory, Centre Hospitalier Universitaire de Québec and Laval University, Quebec City, Canada) ; McGuffog, Lesley (Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom) ; Barrowdale, Daniel (Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom) ; Lee, Andrew (Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom) ; SWE-BRCA, None (Department of Oncology, Lund University, Lund, Sweden) ; Arver, Brita (Department of Oncology, Karolinska University Hospital, Stockholm, Sweden) ; Rantala, Johanna (Department of Clinical Genetics, Karolinska University Hospital, Stockholm, Sweden) ; Loman, Niklas (Department of Oncology, Lund University Hospital, Lund, Sweden) ; Ehrencrona, Hans (Department of Clinical Genetics, Lund University Hospital, Lund, Sweden) ; Olopade, Olufunmilayo I. (Center for Clinical Cancer Genetics and Global Health, University of Chicago Medical Center, Chicago, Illinois, United States of America) ; Beattie, Mary S. (Departments of Medicine, Epidemiology, and Biostatistics, University of California, San Francisco, San Francisco, California, United States of America) ; Domchek, Susan M. (Abramson Cancer Center and Department of Medicine, The University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America) ; Nathanson, Katherine (Abramson Cancer Center and Department of Medicine, The University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, United States of America) ; Rebbeck, Timothy R. (Abramson Cancer Center and Center for Clinical Epidemiology and Biostatistics, The University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, United States of America) ; Arun, Banu K. (University of Texas MD Anderson Cancer Center, Houston, Texas, United States of America) ; Karlan, Beth Y. (Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States of America) ; Walsh, Christine (Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States of America) ; Lester, Jenny (Women's Cancer Program at the Samuel Oschin Comprehensive Cancer Institute, Cedars-Sinai Medical Center, Los Angeles, California, United States of America) ; John, Esther M. (Department of Epidemiology, Cancer Prevention Institute of California, Fremont, California, United States of America) ; Whittemore, Alice S. (Department of Health Research & Policy, Stanford University School of Medicine, Stanford, California, United States of America) ; Daly, Mary B. (Fox Chase Cancer Center, Philadelphia, Pennsylvania, United States of America) ; Southey, Melissa (Genetic Epidemiology Laboratory, Department of Pathology, University of Melbourne, Parkville, Australia) ; Hopper, John (Centre for Molecular, Environmental, Genetic and Analytic Epidemiology, University of Melbourne, Melbourne, Victoria, Australia) ; Terry, Mary B. (Department of Epidemiology, Columbia University, New York, New York, United States of America) ; Buys, Saundra S. (Department of Oncological Sciences, Huntsman Cancer Institute, University of Utah School of Medicine, Salt Lake City, Utah, United States of America) ; Janavicius, Ramunas (Vilnius University Hospital Santariskiu Clinics, Hematology, oncology and transfusion medicine center, Department of Molecular and Regenerative Medicine, Vilnius, Lithuania) ; Dorfling, Cecilia M. (Department of Genetics, University of Pretoria, Pretoria, South Africa) ; van Rensburg, Elizabeth J. (Department of Genetics, University of Pretoria, Pretoria, South Africa) ; Steele, Linda (Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, California, United States of America) ; Neuhausen, Susan L. (Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, California, United States of America) ; Ding, Yuan Chun (Department of Population Sciences, Beckman Research Institute of City of Hope, Duarte, California, United States of America) ; Hansen, Thomas v. O. (Center for Genomic Medicine, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark) ; Jønson, Lars (Center for Genomic Medicine, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark) ; Ejlertsen, Bent (Department of Oncology, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark) ; Gerdes, Anne-Marie (Department of Clinical Genetics, Rigshospitalet, University of Copenhagen, Copenhagen, Denmark) ; Infante, Mar (Institute of Biology and Molecular Genetics, Universidad de Valladolid (IBGM-UVA), Valladolid, Spain) ; Herráez, Belén (Genotyping Unit (CeGen), Spanish National Cancer Centre (CNIO), Madrid, Spain) ; Moreno, Leticia Thais (Genotyping Unit (CeGen), Spanish National Cancer Centre (CNIO), Madrid, Spain) ; Weitzel, Jeffrey N. (Clinical Cancer Genetics, City of Hope, Duarte, California, United States of America) ; Herzog, Josef (Clinical Cancer Genetics, City of Hope, Duarte, California, United States of America) ; Weeman, Kisa (Clinical Cancer Genetics, City of Hope, Duarte, California, United States of America) ; Manoukian, Siranoush (Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan, Italy) ; Peissel, Bernard (Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan, Italy) ; Zaffaroni, Daniela (Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan, Italy) ; Scuvera, Giulietta (Unit of Medical Genetics, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan, Italy) ; Bonanni, Bernardo (Division of Cancer Prevention and Genetics, Istituto Europeo di Oncologia, Milan, Italy) ; Mariette, Frederique (IFOM, Fondazione Istituto FIRC di Oncologia Molecolare and Cogentech Cancer Genetic Test Laboratory, Milan, Italy) ; Volorio, Sara (IFOM, Fondazione Istituto FIRC di Oncologia Molecolare and Cogentech Cancer Genetic Test Laboratory, Milan, Italy) ; Viel, Alessandra (Division of Experimental Oncology 1, Centro di Riferimento Oncologico, IRCCS, Aviano, Italy) ; Varesco, Liliana (Unit of Hereditary Cancer, Department of Epidemiology, Prevention and Special Functions, IRCCS AOU San Martino - IST Istituto Nazionale per la Ricerca sul Cancro, Genoa, Italy) ; Papi, Laura (Unit of Medical Genetics, Department of Biomedical, Experimental and Clinical Sciences, University of Florence, Florence, Italy) ; Ottini, Laura (Department of Molecular Medicine, “Sapienza” University, Rome, Italy) ; Tibiletti, Maria Grazia (UO Anatomia Patologica, Ospedale di Circolo-Università dell'Insubria, Varese, Italy) ; Radice, Paolo (Unit of Molecular bases of genetic risk and genetic testing, Department of Preventive and Predictive Medicine, Fondazione IRCCS Istituto Nazionale Tumori (INT), Milan, Italy) ; Yannoukakos, Drakoulis (Molecular Diagnostics Laboratory IRRP, National Centre for Scientific Research Demokritos Aghia Paraskevi Attikis, Athens, Greece) ; Garber, Judy (Dana-Farber Cancer Institute, Boston, Massachusetts, United States of America) ; Ellis, Steve (Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom) ; Frost, Debra (Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom) ; Platte, Radka (Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom) ; Fineberg, Elena (Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom) ; Evans, Gareth (Genetic Medicine, Manchester Academic Health Sciences Centre, Central Manchester University Hospitals NHS Foundation Trust, Manchester, United Kingdom) ; Lalloo, Fiona (Genetic Medicine, Manchester Academic Health Sciences Centre, Central Manchester University Hospitals NHS Foundation Trust, Manchester, United Kingdom) ; Izatt, Louise (South East Thames Regional Genetics Service, Guy's Hospital London, United Kingdom) ; Eeles, Ros (Oncogenetics Team, The Institute of Cancer Research and Royal Marsden NHS Foundation Trust, London, United Kingdom) ; Adlard, Julian (Yorkshire Regional Genetics Service, Leeds, United Kingdom) ; Davidson, Rosemarie (Ferguson-Smith Centre for Clinical Genetics, Yorkhill Hospitals, Glasgow, United Kingdom) ; Cole, Trevor (West Midlands Regional Genetics Service, Birmingham Women's Hospital Healthcare NHS Trust, Edgbaston, Birmingham, United Kingdom) ; Eccles, Diana (Wessex Clinical Genetics Service, Princess Anne Hospital, Southampton, United Kingdom) ; Cook, Jackie (Sheffield Clinical Genetics Service, Sheffield Children's Hospital, Sheffield, United Kingdom) ; Hodgson, Shirley (Clinical Genetics Department, St Georges Hospital, University of London, London, United Kingdom) ; Brewer, Carole (Department of Clinical Genetics, Royal Devon & Exeter Hospital, Exeter, United Kingdom) ; Tischkowitz, Marc (Department of Clinical Genetics, East Anglian Regional Genetics Service, Addenbrookes Hospital, Cambridge, United Kingdom) ; Douglas, Fiona (Institute of Human Genetics, Centre for Life, Newcastle Upon Tyne Hospitals NHS Trust, Newcastle upon Tyne, United Kingdom) ; Porteous, Mary (South East of Scotland Regional Genetics Service, Western General Hospital, Edinburgh, United Kingdom) ; Side, Lucy (North East Thames Regional Genetics Service, Great Ormond Street Hospital for Children NHS Trust, London, United Kingdom) ; Walker, Lisa (Oxford Regional Genetics Service, Churchill Hospital, Oxford, United Kingdom) ; Morrison, Patrick (Northern Ireland Regional Genetics Centre, Belfast City Hospital, Belfast, United Kingdom) ; Donaldson, Alan (South West Regional Genetics Service, Bristol, United Kingdom) ; Kennedy, John (Academic Unit of Clinical and Molecular Oncology, Trinity College Dublin and St James's Hospital, Dublin, Eire) ; Foo, Claire (Cheshire & Merseyside Clinical Genetics Service, Liverpool Women's NHS Foundation Trust, Liverpool, United Kingdom) ; Godwin, Andrew K. (Department of Pathology and Laboratory Medicine, University of Kansas Medical Center, Kansas City, Kansas, United States of America) ; Schmutzler, Rita Katharina (Centre of Familial Breast and Ovarian Cancer and Centre for Integrated Oncology (CIO), University Hospital of Cologne, Cologne, Germany) ; Wappenschmidt, Barbara (Centre of Familial Breast and Ovarian Cancer and Centre for Integrated Oncology (CIO), University Hospital of Cologne, Cologne, Germany) ; Rhiem, Kerstin (Centre of Familial Breast and Ovarian Cancer and Centre for Integrated Oncology (CIO), University Hospital of Cologne, Cologne, Germany) ; Engel, Christoph (Institute for Medical Informatics, Statistics and Epidemiology, University of Leipzig, Leipzig, Germany) ; Meindl, Alfons (Department of Gynaecology and Obstetrics, Division of Tumor Genetics, Klinikum rechts der Isar, Technical University Munich, Munich, Germany) ; Ditsch, Nina (Department of Gynaecology and Obstetrics, Division of Tumor Genetics, Klinikum rechts der Isar, Technical University Munich, Munich, Germany) ; Arnold, Norbert (Department of Gynecology and Obstetrics, University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany) ; Plendl, Hans Jörg (Institute of Human Genetics, University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany) ; Niederacher, Dieter (Department of Gynaecology and Obstetrics, University Hospital Düsseldorf, Heinrich-Heine University Düsseldorf, Düsseldorf, Germany) ; Sutter, Christian (Institute of Human Genetics, Department of Human Genetics, University Hospital Heidelberg, Heidelberg, Germany) ; Wang-Gohrke, Shan (Department of Gynaecology and Obstetrics, University Hospital Ulm, Ulm, Germany) ; Steinemann, Doris (Institute of Cell and Molecular Pathology, Hannover Medical School, Hannover, Germany) ; Preisler-Adams, Sabine (Institute of Human Genetics, University of Münster, Münster, Germany) ; Kast, Karin (Department of Gynaecology and Obstetrics, University Hospital Carl Gustav Carus, Technical University Dresden, Dresden, Germany) ; Varon-Mateeva, Raymonda (Institute of Human Genetics, Campus Virchov Klinikum, Charite Berlin, Berlin, Germany) ; Gehrig, Andrea (Centre of Familial Breast and Ovarian Cancer, Department of Medical Genetics, Institute of Human Genetics, University Würzburg, Würzburg, Germany) ; Stoppa-Lyonnet, Dominique (Université Paris Descartes, Sorbonne Paris Cité, Paris, France) ; Sinilnikova, Olga M. (INSERM U1052, CNRS UMR5286, Université Lyon 1, Centre de Recherche en Cancérologie de Lyon, Lyon, France) ; Mazoyer, Sylvie (INSERM U1052, CNRS UMR5286, Université Lyon 1, Centre de Recherche en Cancérologie de Lyon, Lyon, France) ; Damiola, Francesca (INSERM U1052, CNRS UMR5286, Université Lyon 1, Centre de Recherche en Cancérologie de Lyon, Lyon, France) ; Poppe, Bruce (Center for Medical Genetics, Ghent University, Ghent, Belgium) ; Claes, Kathleen (Center for Medical Genetics, Ghent University, Ghent, Belgium) ; Piedmonte, Marion (Gynecologic Oncology Group Statistical and Data Center, Roswell Park Cancer Institute, Buffalo, New York, United States of America) ; Tucker, Kathy (Prince of Wales Hospital. Sydney, Australia) ; Backes, Floor (Ohio State University, Columbus Cancer Council, Columbus, Ohio, United States of America) ; Rodríguez, Gustavo (Division of Gynecologic Oncology, NorthShore University HealthSystem, Evanston, Illinois, United States of America) ; Brewster, Wendy (Division of Gynecologic Oncology, NorthShore University HealthSystem, Chicago, Illinois, United States of America) ; Wakeley, Katie (For Tufts Medical Center, Boston, Massachusetts, United States of America) ; Rutherford, Thomas (Yale University School of Medicine, New Haven, Connecticut, United States of America) ; Caldés, Trinidad (Molecular Oncology Laboratory, Hospital Clinico San Carlos, IdISSC, Madrid, Spain) ; Nevanlinna, Heli (Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland) ; Aittomäki, Kristiina (Department of Obstetrics and Gynecology, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland) ; Rookus, Matti A. (Department of Epidemiology, Netherlands Cancer Institute, Amsterdam, The Netherlands) ; van Os, Theo A. M. (Department of Clinical Genetics, Academic Medical Center, Amsterdam, The Netherlands) ; van der Kolk, Lizet (Family Cancer Clinic, Netherlands Cancer Institute, Amsterdam, The Netherlands) ; de Lange, J. L. (Department of Epidemiology, Netherlands Cancer Institute, Amsterdam, The Netherlands) ; Meijers-Heijboer, Hanne E. J. (Department of Clinical Genetics, VU University Medical Centre, Amsterdam, The Netherlands) ; van der Hout, A. H. (University of Groningen, University Medical Center Groningen, Department of Genetics, Groningen, The Netherlands) ; van Asperen, Christi J. (Department of Clinical Genetics, Leiden University Medical Center Leiden, Leiden, The Netherlands) ; Gómez Garcia, Encarna B. (Department of Clinical Genetics and GROW, School for Oncology and Developmental Biology, MUMC, Maastricht, The Netherlands) ; Hoogerbrugge, Nicoline (Department of Human Genetics, Radboud University Nijmegen Medical Centre, Nijmegen, The Netherlands) ; Collée, J. Margriet (Department of Clinical Genetics, Family Cancer Clinic, Erasmus University Medical Center, Rotterdam, The Netherlands) ; van Deurzen, Carolien H. M. (Department of Pathology, Family Cancer Clinic, Erasmus University Medical Center, Rotterdam, The Netherlands) ; van der Luijt, Rob B. (Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands) ; Devilee, Peter (Department of Human Genetics & Department of Pathology, Leiden University Medical Center, Leiden, The Netherlands) ; HEBON, None (The Hereditary Breast and Ovarian Cancer Research Group, Netherlands Cancer Institute, Amsterdam, The Netherlands) ; Olah, Edith (Department of Molecular Genetics, National Institute of Oncology, Budapest, Hungary) ; Lázaro, Conxi (Molecular Diagnostic Unit, Hereditary Cancer Program, IDIBELL-Catalan Institute of Oncology, Barcelona, Spain) ; Teulé, Alex (Genetic Counseling Unit, Hereditary Cancer Program, IDIBELL-Catalan Institute of Oncology, Barcelona, Spain) ; Menéndez, Mireia (Molecular Diagnostic Unit, Hereditary Cancer Program, IDIBELL-Catalan Institute of Oncology, Barcelona, Spain) ; Jakubowska, Anna (Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland) ; Cybulski, Cezary (Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland) ; Gronwald, Jacek (Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland) ; Lubinski, Jan (Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland) ; Durda, Katarzyna (Department of Genetics and Pathology, Pomeranian Medical University, Szczecin, Poland) ; Jaworska-Bieniek, Katarzyna (Postgraduate School of Molecular Medicine, Warsaw Medical University, Warsaw, Poland) ; Johannsson, Oskar Th. (Department of Oncology, Landspitali University Hospital and BMC, Faculty of Medicine, University of Iceland, Reykjavik Iceland) ; Maugard, Christine (Laboratoire de Diagnostic Génétique et Service d'Onco-hématologie, Hopitaux Universitaire de Strasbourg, CHRU Nouvel Hôpital Civil, Strasbourg, France) ; Montagna, Marco (Immunology and Molecular Oncology Unit, Veneto Institute of Oncology IOV - IRCCS, Padua, Italy) ; Tognazzo, Silvia (Immunology and Molecular Oncology Unit, Veneto Institute of Oncology IOV - IRCCS, Padua, Italy) ; Teixeira, Manuel R. (Department of Genetics, Portuguese Oncology Institute, Porto, and Biomedical Sciences Institute (ICBAS), Porto University, Porto, Portugal) ; Healey, Sue (Department of Genetics and Computational Biology, Queensland Institute of Medical Research, Brisbane, Australia) ; Investigators, kConFab (Kathleen Cuningham Consortium for Research into Familial Breast Cancer, Peter MacCallum Cancer Center, Melbourne, Australia) ; Olswold, Curtis (Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, United States of America) ; Guidugli, Lucia (Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, United States of America) ; Lindor, Noralane (Center for Individualized Medicine, Mayo Clinic, Scottsdale, Arizona, United States of America) ; Slager, Susan (Department of Health Sciences Research, Mayo Clinic, Rochester, Minnesota, United States of America) ; Szabo, Csilla I. (Center for Translational Cancer Research, Department of Biological Sciences, University of Delaware, Newark, Delaware, United States of America) ; Vijai, Joseph (Cancer Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America) ; Robson, Mark (Clinical Genetics Service, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America) ; Kauff, Noah (Clinical Genetics Service, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America) ; Zhang, Liying (Diagnostic Molecular Genetics Laboratory, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America) ; Rau-Murthy, Rohini (Clinical Genetics Service, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America) ; Fink-Retter, Anneliese (Department of OB/GYN and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria) ; Singer, Christian F. (Department of OB/GYN and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria) ; Rappaport, Christine (Department of OB/GYN and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria) ; Geschwantler Kaulich, Daphne (Department of OB/GYN and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria) ; Pfeiler, Georg (Department of OB/GYN and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria) ; Tea, Muy-Kheng (Department of OB/GYN and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria) ; Berger, Andreas (Department of OB/GYN and Comprehensive Cancer Center, Medical University of Vienna, Vienna, Austria) ; Phelan, Catherine M. (Department of Cancer Epidemiology, Moffitt Cancer Center, Tampa, Florida, United States of America) ; Greene, Mark H. (Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, Maryland, United States of America) ; Mai, Phuong L. (Clinical Genetics Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Rockville, Maryland, United States of America) ; Lejbkowicz, Flavio (Clalit National Israeli Cancer Control Center, Haifa, Israel) ; Andrulis, Irene (Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada, and Cancer Care Ontario, Departments of Molecular Genetics and Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada) ; Mulligan, Anna Marie (Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Ontario, Canada; Laboratory Medicine Program, University Health Network, Toronto, Ontario, Canada) ; Glendon, Gord (Ontario Cancer Genetics Network: Samuel Lunenfeld Research Institute, Mount Sinai Hospital, Toronto, Ontario, Canada) ; Toland, Amanda Ewart (Division of Human Cancer Genetics, Departments of Internal Medicine and Molecular Virology, Immunology and Medical Genetics, Comprehensive Cancer Center, The Ohio State University, Columbus, Ohio, United States of America) ; Bojesen, Anders (Department of Clinical Genetics, Vejle Hospital, Vejle, Denmark) ; Pedersen, Inge Sokilde (Section of Molecular Diagnostics, Department of Clinical Biochemistry, Aalborg University Hospital, Aalborg, Denmark) ; Sunde, Lone (Department of Clinical Genetics, Aarhus University Hospital, Aarhus, Denmark) ; Thomassen, Mads (Department of Clinical Genetics, Odense University Hospital, Odense, Denmark) ; Kruse, Torben A. (Department of Clinical Genetics, Odense University Hospital, Odense, Denmark) ; Jensen, Uffe Birk (Department of Clinical Genetics, Aarhus University Hospital, Aarhus, Denmark) ; Friedman, Eitan (Sheba Medical Center, Tel Aviv, Israel) ; Laitman, Yael (Sheba Medical Center, Tel Aviv, Israel) ; Shimon, Shani Paluch (Sheba Medical Center, Tel Aviv, Israel) ; Simard, Jacques (Canada Research Chair in Oncogenetics, Cancer Genomics Laboratory, Centre Hospitalier Universitaire de Québec and Laval University, Quebec City, Canada) ; Easton, Douglas F. (Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom) ; Offit, Kenneth (Cancer Biology and Genetics Program, Memorial Sloan-Kettering Cancer Center, New York, New York, United States of America) ; Couch, Fergus J. (Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, Minnesota, United States of America) ; Chenevix-Trench, Georgia (Department of Genetics and Computational Biology, Queensland Institute of Medical Research, Brisbane, Australia) ; Antoniou, Antonis C. (Centre for Cancer Genetic Epidemiology, Department of Public Health and Primary Care, University of Cambridge, Cambridge, United Kingdom) ; Benitez, Javier (Genotyping Unit (CeGen), Spanish National Cancer Centre (CNIO), Madrid, Spain)
Single Nucleotide Polymorphisms (SNPs) in genes involved in the DNA Base Excision Repair (BER) pathway could be associated with cancer risk in carriers of mutations in the high-penetrance susceptibility genes BRCA1 and BRCA2, given the relation of synthetic lethality that exists between one of the components of the BER pathway, PARP1 (poly ADP ribose polymerase), and both BRCA1 and BRCA2. [...]
2014 - 10.1371/journal.pgen.1004256
PLoS Genetics, Vol. 10 (april 2014)  
7.
5 p, 81.9 KB Bases Moleculars de la Transducció de Senyal i el Càncer [42893] / Lizcano de Vega, José Miguel (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Gómez Trias, Néstor ; López Blanco, José Manuel (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Yuste Mateos, Víctor J. (Víctor José) (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Bayascas Ramírez, José Ramón (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Bassols Serra, Anna ; Universitat Autònoma de Barcelona. Facultat de Biociències
1 Providing advanced training on the molecular mechanisms involved in signal transduction pathways and in the control of cell proliferation, and how these mechanisms are altered in the cancer cell. Reviewing and updating key concepts of the field Defining our current knowledge on the field, as well as identifying critical issues to be investigated.
Providing advanced training on the molecular mechanisms involved in signal transduction pathways and in the control of cell proliferation, and how these mechanisms are altered in the cancer cell. Reviewing and updating key concepts of the field 1 Reviewing and updating key concepts of the field Defining our current knowledge on the field, as well as identifying critical issues to be investigated.

2017-18
Màster Universitari en Bioquímica, Biologia Molecular i Biomedicina [1153]
3 documents
8.
5 p, 79.2 KB Avenços en Bioquímica Clínica i Patologia Molecular [42886] / Blanco Vaca, Francisco (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Canalias Reverter, Francesca (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Ordóñez, J. 1952- (Jordi), (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Mora Brugues, Josefina ; Universitat Autònoma de Barcelona. Facultat de Biociències
L'objectiu principal del mòdul és l'aprenentatge especialitzat dels avenços produïts recentment en l'àrea de la Bioquímica Clínica i la Patologia Molecular. Es pretén, doncs, que l'alumne entengui i visualitzi, utilitzant exemples que no pretenen ser exhaustius, quina és la forma en què es generen, desenvolupen i analitzen les aplicacions de la Bioquímica i la Biologia Molecular a la Medicina en general, i a l'àrea de la Medicina de Laboratori (especialitats de Bioquímica Clínica i Patologia Molecular) en particular. [...]
2017-18
Màster Universitari en Bioquímica, Biologia Molecular i Biomedicina [1153]
3 documents
9.
4 p, 80.6 KB Pràctiques Clíniques de Laboratori I [103643] / Ordóñez, J. 1952- (Jordi), (Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular) ; Coll Figa, Pedro (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Lerma Puertas, Enrique ; Antonijoan Arbós, Rosa María ; Blanco Vaca, Francisco (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Gomez Anson, Beatriz ; Universitat Autònoma de Barcelona. Facultat de Medicina
Es tracta d'una assignatura optativa que es pot cursar a partir del tercer curs i que té com a objectiu general que l'estudiant es familiaritzi amb la pràctica professional en context real. L'estudiant s'incorpora en les activitats d'un servei o laboratori assistencial, realitzant tasques assistencials de formació o de recerca de forma supervisada.
Se trata de una asignatura optativa que se puede cursar a partir del tercer curso y que tiene como objetivo general que el estudiante se familiarice con la práctica profesional en contexto real. El estudiante se incorpora en las actividades de un servicio o laboratorio asistencial, realizando tareas asistenciales de formación o de investigación de forma supervisada.

2017-18
Grau en Medicina [1192]
2 documents
10.
48 p, 8.9 MB The first crystal structure of human RNase6 reveals a novel substrate binding and cleavage site arrangement. / Prats-Ejarque, G. (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Arranz-Trullén, J. (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Blanco, JA. (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Pulido, D. (Imperial College London) ; Nogués, MV. (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Moussaoui, M. (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Boix, E. (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
Human RNase 6 is a cationic secreted protein that belongs to the RNase A superfamily. Its expression is induced in neutrophils and monocytes upon bacterial infection, suggesting a role in host defence. [...]
2016 - 10.1042/BCJ20160245
The Biochemical journal, 2016  

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