Dipòsit Digital de Documents de la UAB 3 registres trobats  La cerca s'ha fet en 0.00 segons. 
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17 p, 2.4 MB Tumor expression of cyclin-dependent kinase 5 (Cdk5) is a prognostic biomarker and predicts outcome of oxaliplatin-treated metastatic colorectal cancer patients / Ruiz de Porras, V. (Institut Germans Trias i Pujol) ; Bystrup, Sara (Institut Germans Trias i Pujol) ; Cabrero de las Heras, Sara (Institut Germans Trias i Pujol) ; Musulén, Eva (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Palomero, L. (Bellvitge Institute for Biomedical Research. L'Hospitalet del Llobregat) ; Alonso, M.H. (Department of Clinical Sciences. Faculty of Medicine and Health Sciences. University of Barcelona) ; Nieto Raya, Rocío. (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Arango, Diego (Hospital Universitari Vall d'Hebron. Institut de Recerca) ; Moreno, V. (Department of Clinical Sciences. Faculty of Medicine and Health Sciences. University of Barcelona) ; Queralt, C. (Institut Germans Trias i Pujol) ; Manzano Mozo, José Luís (Institut Germans Trias i Pujol) ; Layos, Laura (Institut Germans Trias i Pujol) ; Bugés, Cristina (Institut Germans Trias i Pujol) ; Martínez Balibrea, Eva (Institut Germans Trias i Pujol) ; Universitat Autònoma de Barcelona
In recent years, an increasing number of studies have shown that elevated expression of cyclin dependent kinase (Cdk5) contributes to the oncogenic initiation and progression of many types of cancers. [...]
2019 - 10.3390/cancers11101540
Cancers, Vol. 11 Núm. 10 (october 2019) , p. 1540  
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17 p, 2.9 MB Curcumin mediates oxaliplatin-acquired resistance reversion in colorectal cancer cell lines through modulation of CXC-Chemokine/NF-κB signalling pathway / Ruiz de Porras, Vicenç (Institut Germans Trias i Pujol) ; Bystrup, Sara (Institut Germans Trias i Pujol) ; Martínez Cardús, Anna (Institut d'Investigació Biomèdica de Bellvitge) ; Pluvinet, Raquel (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Sumoy, Lauro (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Howells, Lynne (University of Leicester. Departament of Cancer Studies) ; James, Mark I. (University of Leicester. Departament of Cancer Studies) ; Iwuji, Chinenye (University of Leicester. Departament of Cancer Studies) ; Manzano, José Luis (Institut Germans Trias i Pujol) ; Layos, Laura (Institut Germans Trias i Pujol) ; Bugés, Cristina (Institut Germans Trias i Pujol) ; Abad, Albert (Hospital Cima Sanitas (Barcelona)) ; Martínez Balibrea, Eva (Institut Germans Trias i Pujol)
Resistance to oxaliplatin (OXA) is a complex process affecting the outcomes of metastatic colorectal cancer (CRC) patients treated with this drug. De-regulation of the NF-κB signalling pathway has been proposed as an important mechanism involved in this phenomenon. [...]
2016 - 10.1038/srep24675
Scientific reports (Nature Publishing Group), Vol. 6 (April 2016)  
3.
20 p, 10.3 MB PKM2 subcellular localization is involved in oxaliplatin resistance acquisition in HT29 human colorectal cancer cell lines / Ginés Molina, Alba (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Bystrup, Sara (Institut Germans Trias i Pujol) ; Ruiz de Porras, Vicenç (Institut Germans Trias i Pujol) ; Guardia, Cristina (Institut Germans Trias i Pujol) ; Musulén Palet, Eva (Institut Germans Trias i Pujol) ; Martínez Cardús, Anna (Institut Germans Trias i Pujol) ; Manzano, José Luis (Institut Germans Trias i Pujol) ; Layos, Laura (Institut Germans Trias i Pujol) ; Abad, Albert (Institut Germans Trias i Pujol) ; Martínez Balibrea, Eva (Institut Germans Trias i Pujol)
Chemoresistance is the main cause of treatment failure in advanced colorectal cancer (CRC). However, molecular mechanisms underlying this phenomenon remain to be elucidated. In a previous work we identified low levels of PKM2 as a putative oxaliplatin-resistance marker in HT29 CRC cell lines and also in patients. [...]
2015 - 10.1371/journal.pone.0123830
PloS one, Vol. 10, No. 5 (May 2015) , p. e0123830  

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