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28 p, 2.9 MB Mouse HORMAD1 and HORMAD2, two conserved meiotic chromosomal proteins, are depleted from synapsed chromosome axes with the help of TRIP13 AAA-ATPase / Wojtasz, Lukasz (Technische Universität Dresden. Institute of Physiological Chemistry (Dresden, Alemanya)) ; Daniel, Katrin (Technische Universität Dresden. Institute of Physiological Chemistry (Dresden, Alemanya)) ; Roig, I., (Ignasi) dir. (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Bolcun-Filas, Ewelina (Cornell University (Nova York, Estats Units d'Amèrica)) ; Xu, Huiling (Peter MacCallum Cancer Centre (Melbourne, Austràlia)) ; Boonsanay, Verawan (Technische Universität Dresden. Institute of Physiological Chemistry (Dresden, Alemanya)) ; Eckmann, Christian R. (Max Planck Institute of Molecular Cell Biology and Genetics (Dresden, Alemanya)) ; Cooke, Howard J. (Western General Hospital (Edimburg, Escòcia)) ; Jasin, Maria (Memorial Sloan-Kettering Cancer Center (Nova York, Estats Units d'Amèrica)) ; Keeney, Scott (Memorial Sloan-Kettering Cancer Center (Nova York, Estats Units d'Amèrica)) ; McKay, Michael J. (Australian National University. Department of Radiation Oncology (Austràlia)) ; Toth, Attila (Technische Universität Dresden. Institute of Physiological Chemistry (Dresden, Alemanya))
Meiotic crossovers are produced when programmed double-strand breaks (DSBs) are repaired by recombination from homologous chromosomes (homologues). In a wide variety of organisms, meiotic HORMA-domain proteins are required to direct DSB repair towards homologues. [...]
2009 - 10.1371/journal.pgen.1000702
PLoS Genetics, Vol. 5, N. 10 (October 2009) , p. e1000702  

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