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8 p, 1.5 MB |
CD44-negative parietal-epithelial cell staining in minimal change disease : Association with clinical features, response to corticosteroids and kidney outcome
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Roca, Neus (Universitat de Vic) ;
Jatem, Elias (Hospital Universitari Arnau de Vilanova) ;
Abo, Anabel (Institut de Recerca Biomèdica Dr Pifarré) ;
Santacana, Maria (Institut de Recerca Biomèdica Dr Pifarré) ;
Cruz, Alejandro (Hospital Universitari Vall d'Hebron) ;
Madrid, Álvaro (Hospital Sant Joan de Dèu Barcelona) ;
Fraga Rodríguez, Gloria María (Institut d'Investigació Biomèdica Sant Pau) ;
Martin, Marisa (Hospital Universitari Arnau de Vilanova) ;
Gonzalez, Jorge (Hospital Universitari Arnau de Vilanova) ;
Martinez, Cristina (Institut de Recerca Biomèdica Dr Pifarré) ;
Balius, Anna (Fundació Althaia de Manresa) ;
Segarra, Alfons (Hospital Universitari Arnau de Vilanova) ;
Universitat Autònoma de Barcelona
Activation of parietal-epithelial cells (PECs) with neo-expression of CD44 has been found to play a relevant role in the development of focal and segmental glomerulosclerosis (FSGS). The aim of this study was to analyse whether the expression of CD44 by PECs in biopsies of minimal change disease (MCD) is associated with the response to corticosteroids, with kidney outcomes and/or can be considered an early sign of FSGS. [...]
2022 -  10.1093/ckj/sfab215
Clinical Kidney Journal, Vol. 15 Núm. 3 (january 2022) , p. 545-552
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7 p, 638.1 KB |
Associations of hypomagnesemia in patients seeking a first treatment of alcohol use disorder
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Hernandez-Rubio, Anna (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Sanvisens, Arantza (Girona Biomedical Research Institute. Clinical Pharmacology Department) ;
Barbier-Torres, Lucía (Cedars-Sinai Medical Center) ;
Blanes, Rafael (Hospital Universitari Son Dureta (Palma de Mallorca, Balears)) ;
Miquel, Laia (Universitat de Barcelona) ;
Torrens, Marta (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Rubio, Gabriel (Universidad Complutense de Madrid) ;
Bolao, Ferran (Universitat de Barcelona) ;
Zuluaga Cruz, Andrea Paola (Clinical Pharmacology Department) ;
Fuster, Daniel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Rodríguez de Fonseca, Fernando (Instituto de Investigación Biomédica de Málaga) ;
Farre, Magi (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Muga, Roberto (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Universitat Autònoma de Barcelona
INTRODUCTION: Hypomagnesemia (hypoMg) has not yet been extensively studied in alcohol use disorder (AUD) . We hypothesize that chronic, excessive alcohol consumption favors oxidative stress and pro-inflammatory alterations that may be exacerbated by hypoMg. [...]
2023 - 10.1016/j.drugalcdep.2023.109822
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20 p, 15.9 MB |
Theoretical Study of the Arachidonic Acid Conversion into Leukotriene A4 Catalyzed by Human 5-Lipoxygenase : Hydroperoxidation and Epoxidation Mechanisms and Arachidonic Acid Active Site Access
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Cruz Saez, Alejandro (Universitat Autònoma de Barcelona. Departament de Química) ;
González-Lafont, Àngels (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Lluch López, Josep Maria (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí")
Inflammation is at the base of many different diseases. Leukotrienes (LTs) are pro-inflammatory mediators derived from arachidonic acid (AA), which play significant roles in acute inflammation. Lipoxins are specialized pro-resolving mediators (SPMs), also formed from AA, that promote the resolution of acute inflammation. [...]
2024 - 10.1021/acscatal.3c04954
ACS catalysis, Vol. 14, Issue 2 (January 2024) , p. 637-656
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14 p, 1.2 MB |
Inflammatory Response of Ischemic Tolerance in Circulating Plasma : Preconditioning-Induced by Transient Ischemic Attack (TIA) Phenomena in Acute Ischemia Patients (AIS)
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Colàs-Campàs, L. (Institut de Recerca Biomèdica de Lleida) ;
Farre, J. (Hospital Universitari Arnau de Vilanova) ;
Mauri-Capdevila, G. (Hospital Universitari Arnau de Vilanova) ;
Molina-Seguín, J. (Institut de Recerca Biomèdica de Lleida) ;
Aymerich, Nuria (Complejo Hospitalario de Navarra) ;
Ois, Angel (Hospital del Mar (Barcelona, Catalunya)) ;
Roquer González, Jaume (Hospital del Mar (Barcelona, Catalunya)) ;
Tur, S. (Hospital Universitari Son Espases (Palma de Mallorca, Balears)) ;
García-Carreira, Maria del Carmen (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Martí-Fàbregas, Joan (Institut d'Investigació Biomèdica Sant Pau) ;
Cruz-Culebras, A. (Hospital Universitario Ramón y Cajal (Madrid)) ;
Segura, T. (Complejo Hospitalario Universitario de Albacete) ;
Arque, Gloria (Institut de Recerca Biomèdica de Lleida) ;
Purroy, Francisco (Hospital Arnau de Vilanova (Lleida, Catalunya)) ;
Universitat Autònoma de Barcelona
Ischemic tolerance (IT) refers to a state where cells are resistant to the damaging effects caused by periods of ischemia. In a clinical scenario, the IT phenomenon would be activated by a recent transient ischemic attack (TIA) before an ischemic stroke (IS). [...]
2020 - 10.3389/fneur.2020.552470
Frontiers in neurology, Vol. 11 (29 2020) , p. 552470
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13 p, 1.9 MB |
Sentiment Analysis in Understanding the Potential of Online News in the Public Health Crisis Response
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Marques, Thiago (Federal University of Rio Grande do Norte. Department of Informatics and Applied Mathematics) ;
Cezário, Sidemar (Federal University of Rio Grande do Norte. Department of Informatics and Applied Mathematics) ;
Lacerda, Juciano (Federal University of Rio Grande do Norte. Department of Social Communication) ;
Pinto, Rafael (Federal University of Rio Grande do Norte. Department of Informatics and Applied Mathematics) ;
Silva, Lyrene (Federal University of Rio Grande do Norte. Department of Informatics and Applied Mathematics) ;
Santana, Orivaldo (Federal University of Rio Grande do Norte. Laboratory of Technological Innovation in Health (LAIS)) ;
Ribeiro, Anna Giselle (Federal University of Rio Grande do Norte. Laboratory of Technological Innovation in Health (LAIS)) ;
Souza Cruz, Agnaldo (Federal University of Rio Grande do Norte. Laboratory of Technological Innovation in Health (LAIS)) ;
Miranda, Angélica Espinosa (Brasília. Ministry of Health) ;
Cadaxa, Aedê (Brasília. Ministry of Health) ;
Sanjuán Núñez, Lucía (Universitat Autònoma de Barcelona. Departament d'Antropologia Social i Cultural) ;
Gonçalo Oliveira, Hugo (University of Coimbra. Department of Informatics Engineering (DEI)) ;
Atun, Rifat (Harvard University. Department of Global Health and Population) ;
Valentim, Ricardo (Federal University of Rio Grande do Norte. Laboratory of Technological Innovation in Health (LAIS))
This study analyzes online news disseminated throughout the pre-, during-, and post-intervention periods of the "Syphilis No!" Project, which was developed in Brazil between November 2018 and March 2019. [...]
2022 - 10.3390/ijerph192416801
International journal of environmental research and public health, Vol. 19 (december 2022) , article number 16801
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21 p, 4.8 MB |
Different Structures-Similar Effect : Do Substituted 5-(4-Methoxyphenyl)-1 H -indoles and 5-(4-Methoxyphenyl)-1 H -imidazoles Represent a Common Pharmacophore for Substrate Selective Inhibition of Linoleate Oxygenase Activity of ALOX15?
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Zhuravlev, Alexander (Russian Technological University. Lomonosov Institute of Fine Chemical Technologies) ;
Cruz Saez, Alejandro (Universitat Autònoma de Barcelona. Departament de Química) ;
Aksenov, Vladislav (Shemyakin-Ovchinnikov Institute of Bioorganic Chemistry) ;
Golovanov, Alexey (Russian Technological University. Lomonosov Institute of Fine Chemical Technologies) ;
Lluch López, Josep Maria (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Kuhn, Hartmut (Charite-University Medicine Berlin. Department of Biochemistry) ;
González-Lafont, Àngels (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Ivanov, Igor (Russian Technological University. Lomonosov Institute of Fine Chemical Technologies)
Mammalian 15-lipoxygenases (ALOX15) are lipid peroxidizing enzymes that exhibit variable functionality in different cancer and inflammation models. The pathophysiological role of linoleic acid- and arachidonic acid-derived ALOX15 metabolites rendered this enzyme a target for pharmacological research. [...]
2023 - 10.3390/molecules28145418
Molecules, Vol. 28, Issue 14 (July 2023) , art. 5418
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11 p, 473.9 KB |
Improving the detection of infectious diseases in at-risk migrants with an innovative integrated multi-infection screening digital decision support tool (IS-MiHealth) in primary care : a pilot cluster-randomized-controlled trial
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Sequeira-Aymar, E. (Hospital Clínic i Provincial de Barcelona) ;
Cruz, Angeline (Hospital Clínic i Provincial de Barcelona) ;
Serra-Burriel, Miquel ;
di Lollo, Ximena (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ;
Gonçalves, A. Q (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Camps-Vilà, Laura (Institut Català de la Salut) ;
Monclus-Gonzalez, Marta M (Institut Català de la Salut) ;
Revuelta-Muñoz, Elisa M (Institut Català de la Salut) ;
Busquet Solé, Nuria (Institut Català de la Salut) ;
Sarriegui-Domínguez, Susana (Institut Català de la Salut) ;
Casellas, Aina (Hospital Clínic i Provincial de Barcelona) ;
Dalmau Llorca, M. Rosa (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Aguilar Martín, Carina (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Jacques-Aviñó, Constanza (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ;
Hargreaves, Sally (St. George's University of London) ;
Requena-Méndez, Ana (Hospital Clínic i Provincial de Barcelona) ;
Universitat Autònoma de Barcelona
There are major shortfalls in the identification and screening of at-risk migrant groups. This study aims to evaluate the effectiveness of a new digital tool (IS-MiHealth) integrated into the electronic patient record system of primary care centres in detecting prevalent migrant infections. [...]
2021 - 10.1093/jtm/taab100
Journal of Travel Medicine, Vol. 29 (july 2021)
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7 p, 111.3 KB |
Tècniques de navegació i control del trànsit aeri [101750]
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Cruz Gonzalez, Alba ;
Universitat Autònoma de Barcelona.
Escola d'Enginyeria ;
Universitat Autònoma de Barcelona.
Escola Tècnica Superior d'Enginyeria
En aquesta assignatura es revisen tecnologies noves i tradicionals aplicades a l'aviació. Consta de tres blocs: fonaments de navegació aèria, sistemes de navegació i tècniques de control. D'aquesta manera es fa una anàlisi dels aspectes principals de la navegació aèria començant amb l'estudi de les ciències relacionades per centrar-nos posteriorment en les àrees en què es compon el sistema. [...]
This subject reviews new and traditional technologies applied to aviation. It consists of three blocks: air navigation fundamentals, navigation systems, and control techniques. In this way, an analysis of the main aspects of air navigation is carried out, starting with the study of the related sciences and then focusing on the areas the system is composed. [...]
En esta asignatura se revisan tecnologías nuevas y tradicionales aplicadas a la aviación. Consta de tres bloques: fundamentos de navegación aérea, sistemas de navegación y técnicas de control. [...]
2023-24
Pla d' Estudis de Gestió Aeronàutica [829]
3 documents
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10.
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14 p, 4.8 MB |
Tumor microenvironment gene expression profiles associated to complete pathological response and disease progression in resectable NSCLC patients treated with neoadjuvant chemoimmunotherapy
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Casarrubios, Marta (Instituto de Investigación Sanitaria Puerta de Hierro - Segovia de Arana) ;
Provencio, Mariano (Instituto de Investigación Sanitaria Puerta de Hierro - Segovia de Arana) ;
Nadal, Ernest (Institut d'Investigació Biomèdica de Bellvitge) ;
Insa, Amelia (Hospital Clínic Universitari (València)) ;
Del Rosario García-Campelo, María (Complejo Hospitalario Universitario de A Coruña) ;
Lázaro, Martín (Hospital Universitario de Vigo) ;
Dómine, Manuel (Hospital Universitario Fundación Jiménez Díaz) ;
Majem, Margarita (Institut d'Investigació Biomèdica Sant Pau) ;
Rodríguez-Abreu, Delvys (Hospital Universitario Insular de Gran Canaria) ;
Martinez-Marti, Alex (Vall d'Hebron Institut d'Oncologia) ;
de Castro, Javier (Hospital Universitario La Paz (Madrid)) ;
Cobo, Manuel (Instituto de Investigación Biomédica de Málaga) ;
López-Vivanco, Guillermo (Hospital Universitario de Cruces (Barakaldo, País Basc)) ;
Del Barco Morillo, Edel (Hospital Universitario de Salamanca) ;
Bernabé, Reyes (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Viñolas, Nuria (Hospital Clínic i Provincial de Barcelona) ;
Barneto Aranda, Isidoro (Hospital Universitario Reina Sofía (Còrdova, Espanya)) ;
Massuti, Bartomeu (Hospital General Universitario de Alicante (Alacant, País Valencià)) ;
Sierra-Rodero, Belén (Instituto de Investigación Sanitaria Puerta de Hierro - Segovia de Arana) ;
Martinez-Toledo, Cristina (Instituto de Investigación Sanitaria Puerta de Hierro - Segovia de Arana) ;
Fernández-Miranda, Ismael (Instituto de Investigación Sanitaria Puerta de Hierro - Segovia de Arana) ;
Serna-Blanco, Roberto (Instituto de Investigación Sanitaria Puerta de Hierro - Segovia de Arana) ;
Romero, Atocha (Instituto de Investigación Sanitaria Puerta de Hierro - Segovia de Arana) ;
Calvo, Virginia (Instituto de Investigación Sanitaria Puerta de Hierro - Segovia de Arana) ;
Cruz-Bermúdez, Alberto (Instituto de Investigación Sanitaria Puerta de Hierro - Segovia de Arana)
Background Neoadjuvant chemoimmunotherapy for non-small cell lung cancer (NSCLC) has improved pathological responses and survival rates compared with chemotherapy alone, leading to Food and Drug Administration (FDA) approval of nivolumab plus chemotherapy for resectable stage IB-IIIA NSCLC (AJCC 7th edition) without ALK or EGFR alterations. [...]
2022 - 10.1136/jitc-2022-005320
Journal for immunotherapy of cancer, Vol. 10 Núm. 9 (september 2022) , p. e005320
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