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9 p, 612.9 KB Bariatric surgery increases the rate of major fracture : self-controlled case series study in Clinical Practice Research Datalink / Robinson, Danielle E. (University of Oxford) ; Douglas, Ian (London School of Hygiene & Tropical) ; Tan, Garry D. (The National Institute for Health Research (NIHR) Oxford Biomedical Research Centre) ; Delmestri, Antonella (University of Oxford) ; Judge, Andrew (University of Bristol) ; Cooper, Cyrus (University of Oxford) ; Javaid, M. Kassim (University of Southampton) ; Strauss, Victoria Y. (University of Oxford) ; Prieto-Alhambra, Daniel (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ; Universitat Autònoma de Barcelona
Conflicting results exist about the relationship between bariatric surgery and fracture risk. Also, prediction of who is at increased risk of fracture after bariatric surgery is not currently available. [...]
2021 - 10.1002/jbmr.4405
Journal of Bone and Mineral Research, Vol. 36 (july 2021) , p. 2153-2161  
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15 p, 1.4 MB Comparative anti-fracture effectiveness of different oral anti-osteoporosis therapies based on "real-world" data : a meta-analysis of propensity-matched cohort findings from the UK Clinical Practice Research Database and the Catalan SIDIAP Database / Khalid, Sara (University of Oxford. NIHR Biomedical Research Centre) ; Calderon-Larrañaga, Sara (Family and Community Medicine Teaching Unit of Granada. Cartuja University Health Centre. Andalusian Health Service (SAS), Granada, Spain) ; Hawley, Samuel (University of Oxford. NIHR Biomedical Research Centre) ; Ali, M. Sanni (London School of Hygiene and Tropical Medicine, London, United Kingdom) ; Judge, Andrew (Bristol NIHR Biomedical Research Centre (Bristol, Regne Unit)) ; Arden, N. K (University of Oxford. Arthritis Research UK Centre for Sport, Exercise, and Osteoarthritis) ; van Staa, Tjeerd (Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, the Netherlands) ; Cooper, Cyrus (NIHR Southampton Biomedical Research Centre, University of Southampton and University Hospital Southampton NHS Foundation Trust, Southampton, United Kingdom) ; Javaid, Muhammad Kassim (University of Oxford. NIHR Biomedical Research Centre) ; Prieto-Alhambra, Daniel (Institut Universitari d'Investigació en Atenció Primària Jordi Gol) ; Universitat Autònoma de Barcelona
This paper aims to compare the clinical effectiveness of oral anti-osteoporosis drugs based on the observed risk of fracture while on treatment in primary care actual practice. We investigated two primary care records databases covering UK National Health Service (Clinical Practice Research Datalink, CPRD) and Catalan healthcare (Information System for Research in Primary Care, SIDIAP) patients during 1995-2014 and 2006-2014, respectivey. [...]
2018 - 10.2147/CLEP.S164112
Clinical Epidemiology, Vol. 10 (october 2018) , p. 1417-1431  
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8 p, 2.2 MB Prevalence and Mortality of Individuals With X-Linked Hypophosphatemia : A United Kingdom Real-World Data Analysis / Hawley, Samuel (University of Oxford. Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences) ; Shaw, Nick J. (Institute of Metabolism & Systems Research, University of Birmingham) ; Delmestri, Antonella (Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford) ; Prieto-Alhambra, Daniel (Universitat Autònoma de Barcelona) ; Cooper, Cyrus (MRC Lifecourse Epidemiology Unit, University of Southampton) ; Pinedo-Villanueva, Rafael (Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford) ; Javaid, M. Kassim (MRC Lifecourse Epidemiology Unit, University of Southampton)
X-linked hypophosphatemia (XLH) is a rare multisystemic disease with a prominent musculoskeletal phenotype. We aim here to improve understanding of the prevalence of XLH across the life course and of overall survival among people with XLH. [...]
2020 - 10.1210/clinem/dgz203
The journal of clinical endocrinology & metabolism, Vol. 105 Num. 3 (March 2020)  
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8 p, 1.6 MB Unplanned admissions for patients with myeloma in the UK : Low frequency but high costs / Kolovos, Spyros (University of Oxford. Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences) ; Nador, Guido (Oxford University Hospitals NHS Trust) ; Kishore, Bhuvan (Heart of England NHS Foundation Trust) ; Streetly, Matthew (King's College London) ; Rabin, Neil K. (Department of Haematology, University College London Hospitals NHS Foundation Trust) ; Chantry, Andrew D. (Sheffield Teaching Hospitals NHS Foundation Trust (Sheffield, Regne Unit)) ; Yong, Kwee (UCL Cancer Institute (Londres, Regne Unit)) ; Ashcroft, John (Department of Haematology, Mid Yorkshire NHS Trust) ; Bowcock, Stella (King's College Hospital NHS Foundation Trust) ; Drayson, Mark T. (Institute of Immunology and Immunotherapy, University of Birmingham) ; Ramasamy, Karthik (Oxford University Hospitals NHS Trust) ; Prieto-Alhambra, Daniel (Universitat Autònoma de Barcelona) ; Cooper, Cyrus (NIHR Oxford Biomedical Research Centre) ; Javaid, M. Kassim (Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford) ; Pinedo-Villanueva, Rafael (Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, University of Oxford)
Multiple myeloma (MM) is associated with high healthcare resource utilisation and increasing hospitalisation rates. The aim of this study was to characterise the hospital use by patients with MM in the English National Health Service (NHS). [...]
2019 - 10.1016/j.jbo.2019.100243
Journal of Bone Oncology, Vol. 17 (august 2019)  
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7 p, 376.1 KB Clinical effectiveness of orthogeriatric and fracture liaison service models of care for hip fracture patients : population-based longitudinal study / Hawley, Samuel (University of Oxford) ; Javaid, M. Kassim (MRC Lifecourse Epidemiology Unit, University of Southampton) ; Prieto-Alhambra, Daniel (Institut Hospital del Mar d'Investigacions Mèdiques) ; Lippett, Janet (Royal Berkshire NHS Foundation Trust, Reading) ; Sheard, Sally (University of Oxford) ; Arden, N. K (MRC Lifecourse Epidemiology Unit, University of Southampton) ; Cooper, Cyrus (MRC Lifecourse Epidemiology Unit, University of Southampton) ; Judge, Andrew (MRC Lifecourse Epidemiology Unit, University of Southampton) ; Universitat Autònoma de Barcelona
Objectives: to evaluate orthogeriatric and nurse-led fracture liaison service (FLS) models of post-hip fracture care in terms of impact on mortality (30 days and 1 year) and second hip fracture (2 years). [...]
2016 - 10.1093/ageing/afv204
Age and Ageing, Vol. 45 (january 2016) , p. 236-242  

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