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Genome-wide association study of lifetime cannabis use based on a large meta-analytic sample of 32 330 subjects from the International Cannabis Consortium
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Stringer, Sven (Department of Psychiatry, Academic Medical Centre Amsterdam) ;
Minica, C. C. (Department of Biological Psychology/Netherlands Twin Register, VU University) ;
Verweij, Karin (Department of Developmental Psychology and EMGO Institute for Health and Care Research, VU University) ;
Mbarek, Hamdi (Department of Biological Psychology/Netherlands Twin Register, VU University) ;
Bernard, Manon (The Hospital for Sick Children Research Institute (Toronto, Canadà)) ;
Derringer, Jaime (Department of Psychology, University of Illinois Urbana-Champaign) ;
van Eijk, Kristel R. (Department of Human Neurogenetics, Brain Center Rudolf Magnus, University Medical Center Utrecht) ;
Isen, Joshua (Department of Psychology, University of Minnesota) ;
Loukola, Anu-Maria (Department of Public Health, Hjelt Institute, University of Helsinki) ;
Maciejewski, Dominique F. (Department of Developmental Psychology and EMGO Institute for Health and Care Research, VU University) ;
Mihailov, Evelin (Estonian Genome Center, University of Tartu) ;
van der Most, Peter J. (Department of Epidemiology, University Medical Center Groningen, University of Groningen) ;
Sánchez-Mora, Cristina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Roos, Leonie (King's College London) ;
Sherva, Richard (Biomedical Genetics Department, Boston University School of Medicine) ;
Walters, Raymond K. (Department of Medicine, Harvard Medical School) ;
Ware, Jennifer J. (MRC Integrative Epidemiology Unit (IEU), University of Bristol) ;
Abdellaoui, Abdel (Department of Biological Psychology/Netherlands Twin Register, VU University) ;
Bigdeli, Tim B. (Department of Psychiatry, Virginia Institute for Psychiatric and Behavior Genetics, Virginia Commonwealth University) ;
Branje, Susan (Research Centre Adolescent Development, Utrecht University) ;
Brown, S. A. (Department of Psychology and Psychiatry, University of California San Diego) ;
Bruinenberg, M. (The LifeLines Cohort Study, University of Groningen) ;
Casas, M. (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Esko, T. (Estonian Genome Center, University of Tartu) ;
García-Martinez, Iris (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Gordon, Scott D. (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ;
Harris, J. M. (King's College London) ;
Hartman, Catharina A (Department of Psychiatry, University Medical Center Groningen, University of Groningen) ;
Henders, Anjali K (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ;
Heath, A. C. (Department of Psychiatry, Washington University School of Medicine) ;
Hickie, Ian B. (Brain and Mind Research Institute, University of Sydney) ;
Hickman, M. (School of Social and Community Medicine, University of Bristol) ;
Hopfer, C. J. (Department of Psychiatry, University of Colorado Denver) ;
Hottenga, J. J. (Department of Biological Psychology/Netherlands Twin Register, VU University) ;
Huizink, A. C. (Department of Developmental Psychology and EMGO Institute for Health and Care Research, VU University) ;
Irons, D. E. (Department of Psychology, University of Minnesota) ;
Kahn, R. S. (Department of Human Neurogenetics, Brain Center Rudolf Magnus, University Medical Center Utrecht) ;
Korhonen, T. (Department of Mental Health and Substance Abuse Services, National Institute for Health and Welfare) ;
Kranzler, H. R. (Department of Psychiatry, University of Pennsylvania Perelman School of Medicine) ;
Krauter, K. (Department of Molecular, Cellular and Developmental Biology, University of Colorado Boulder) ;
van Lier, P. A. C. (Department of Developmental Psychology and EMGO Institute for Health and Care Research, VU University) ;
Lubke, G. H. (Department of Psychology, University of Notre Dame) ;
Madden, P. A. F. (Department of Psychiatry, Washington University School of Medicine) ;
Mägi, Reedik (Estonian Genome Center, University of Tartu) ;
McGue, M. K. (Department of Psychology, University of Minnesota) ;
Medland, S. E. (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ;
Meeus, W. H. J. (Developmental Psychology, Tilburg University) ;
Miller, M. B. (Department of Psychology, University of Minnesota) ;
Montgomery, G. W. (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ;
Nivard, M. G. (Department of Biological Psychology/Netherlands Twin Register, VU University) ;
Nolte, Ilja Maria (University Medical Center Groningen, University of Groningen) ;
Oldehinkel, Albertine J. (Interdisciplinary Center for Pathology and Emotion Regulation, University Medical Center Groningen, University of Groningen) ;
Pausova, Zdenka (University of Toronto) ;
Qaiser, Beenish (Hjelt Institute, University of Helsinki) ;
Quaye, Lydia (King's College London) ;
Ramos-Quiroga, Josep Antoni (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Richarte, Vanesa (Hospital Universitari Vall d'Hebron) ;
Rose, Richard J. (Indiana University Bloomington) ;
Shin, Jean (The Hospital for Sick Children Research Institute (Toronto, Canàda)) ;
Stallings, Michael C. (Institute for Behavioral Genetics, University of Colorado Boulder) ;
Stiby, Alexander I (School of Social and Community Medicine, University of Bristol) ;
Wall, Tamara L. (University of California San Diego) ;
Wright, Margaret J (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ;
Koot, Hans (Department of Developmental Psychology and EMGO Institute for Health and Care Research, VU University) ;
Paus, Tomáš (Center for the Developing Brain, Child Mind Institute New York) ;
Hewitt, John (University of Colorado Boulder. Department of Psychology and Neuroscience) ;
Ribasés Haro, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Kaprio, Jaakko (Institute for Molecular Medicine Finland, University of Helsinki) ;
Boks, Marco P. (Brain Center Rudolf Magnus, University Medical Center Utrecht) ;
Snieder, Harold (University Medical Center Groningen) ;
Spector, Tim David (King's College London) ;
Munafo, Marcus (UK Centre for Tobacco and Alcohol Studies and School of Experimental Psychology, University of Bristol) ;
Metspalu, Andres (University of Tartu. Estonian Genome Center (Estònia)) ;
Gelernter, Joel E. (Yale University School of Medicine and VA CT) ;
Boomsma, Dorret I. (Neuroscience Campus Amsterdam) ;
Iacono, William G. (University of Minnesota) ;
Martin, Nicholas G. (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ;
Gillespie, Nathan A. (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ;
Derks, Eske M. (Academic Medical Centre) ;
Vink, Jacqueline M. (Behavioural Science Institute, Radboud University) ;
Universitat Autònoma de Barcelona
Cannabis is the most widely produced and consumed illicit psychoactive substance worldwide. Occasional cannabis use can progress to frequent use, abuse and dependence with all known adverse physical, psychological and social consequences. [...]
2016 -  10.1038/tp.2016.36
Translational psychiatry, Vol. 6 (03 2016) , p. e769
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Rare coding variants and X-linked loci associated with age at menarche
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Lunetta, Kathryn L. (Boston University School of Public Health (Estats Units d'Amèrica)) ;
Day, Felix R. (University of Cambridge. School of Clinical Medicine (Gran Bretanya)) ;
Sulem, Patrick (deCODE Genetics (Reykjavík, Islàndia)) ;
Ruth, Katherine S. (University of Exeter. Medical School (Gran Bretanya)) ;
Tung, Joyce Y. (23andMe (California, Estats Units d'Amèrica)) ;
Hinds, David A. (23andMe (California, Estats Units d'Amèrica)) ;
Esko, Tõnu (University of Tartu. Estonian Genome Center (Estònia)) ;
Elks, Cathy E. (University of Cambridge. School of Clinical Medicine (Gran Bretanya)) ;
Altmaier, Elisabeth (Helmholtz Zentrum München (Alemanya)) ;
He, Chunyan (Fairbanks School of Public Health (Indianapolis, Estats Units d'Amèrica)) ;
Huffman, Jennifer E. (University of Edinburgh. Institute of Genetics and Molecular Medicine (Gran Bretanya)) ;
Mihailov, Evelin (University of Tartu. Estonian Genome Center (Estònia)) ;
Porcu, Eleonora (Institute of Genetics and Biomedical Research (Sardinia, Itàlia)) ;
Robino, Antonietta (Institute for Maternal and Child Health (Trieste, Itàlia)) ;
Rose, Lynda M. (Brigham and Women's Hospital (Boston, Estats Units d'Amèrica)) ;
Schick, Ursula M. (Fred Hutchinson Cancer Research Center (Seattle, Estats Units d'Amèrica)) ;
Stolk, Lisette (Erasmus University Rotterdam) ;
Teumer, Alexander (University Medicine Greifswald (Alemanya)) ;
Thompson, Deborah J. (University of Cambridge. Centre for Cancer Genetic Epidemiology) ;
Traglia, Michela (San Raffaele Scientific Institute (Milà, Itàlia)) ;
Wang, Carol A. (University of Western Australia. School of Women's and Infants' Health (Crawley, Austràlia)) ;
Yerges-Armstrong, Laura M. (University of Maryland School of Medicine (Estats Units d'Amèrica)) ;
Antoniou, Antonis C. (University of Cambridge. Centre for Cancer Genetic Epidemiology) ;
Barbieri, Caterina (San Raffaele Scientific Institute (Milà, Itàlia)) ;
Coviello, Andrea D. (Boston University School of Medicine (Estats Units d'Amèrica)) ;
Cucca, Francesco (Institute of Genetics and Biomedical Research (Sardinia, Itàlia)) ;
Demerath, Ellen W. (University of Minnesota (Minneapolis, Estats Units d'Amèrica)) ;
Dunning, Alison M. (University of Cambridge. Centre for Cancer Genetic Epidemiology) ;
Gandin, Ilaria (Institute for Maternal and Child Health (Trieste, Itàlia)) ;
Grove, Megan L. (University of Texas Health Science Center at Houston (Estats Units d'Amèrica)) ;
Gudbjartsson, Daniel F. (deCODE Genetics (Reykjavík, Islàndia)) ;
Hocking, Lynne J. (University of Aberdeen (Regne Unit)) ;
Hofman, Albert (Erasmus MC (Rotterdam, Paisos Baixos)) ;
Huang, Jinyan (Shanghai Jiao Tong University School of Medicine) ;
Jackson, Rebecca D. (The Ohio State University (Estats Units d'Amèrica)) ;
Karasik, David (Harvard Medical School (Boston, Estats Units d'Amèrica)) ;
Kriebel, Jennifer (Helmholtz Zentrum München (Alemanya)) ;
Lange, Ethan M. (University of North Carolina. Department of Genetics (Estats Units d'Amèrica)) ;
Lange, Leslie A. (University of North Carolina. Department of Genetics (Estats Units d'Amèrica)) ;
Langenberg, Claudia (University of Cambridge. School of Clinical Medicine (Gran Bretanya)) ;
Li, Xin (Harvard T.H. Chan School of Public Health (Boston, Estats Units d'Amèrica)) ;
Luan, Jian'an (University of Cambridge. School of Clinical Medicine (Gran Bretanya)) ;
Mägi, Reedik (University of Tartu. Estonian Genome Center (Estònia)) ;
Morrison, Alanna C. (University of Texas Health Science Center at Houston (Estats Units d'Amèrica)) ;
Padmanabhan, Sandosh (University of Glasgow. Institute of Cardiovascular and Medical Sciences (Gran Bretanya)) ;
Pirie, Ailith (University of Cambridge. Centre for Cancer Genetic Epidemiology) ;
Polasek, Ozren (University of Split. School of Medicine (Croàcia)) ;
Porteous, David (University of Edinburgh.Institute of Genetics and Molecular Medicine (Gran Bretanya)) ;
Reiner, Alex P. (Fred Hutchinson Cancer Research Center (Seattle, Estats Units d'Amèrica)) ;
Rivadeneira, Fernando (Erasmus University Rotterdam) ;
Rudan, Igor (University of Edinburgh. Institute for Population Health Sciences and Informatics (Gran Bretanya)) ;
Sala, Cinzia F. (San Raffaele Scientific Institute (Milà, Itàlia)) ;
Schlessinger, David (National Institute on Aging (Baltimore, Estats Units d'Amèrica)) ;
Scott, Robert A. (University of Cambridge. School of Clinical Medicine (Gran Bretanya)) ;
Stöckl, Doris (German Research Center for Environmental Health (Germany)) ;
Visser, J. (Erasmus University Rotterdam) ;
Völker, Uwe (Greifswald Medical School (Alemanya)) ;
Vozzi, Diego (Institute for Maternal and Child Health (Trieste, Itàlia)) ;
Wilson, James G. (University of Mississippi. Department of Physiology and Biophysics (Estats Units d'Amèrica)) ;
Zygmunt, Marek (Greifswald Medical School (Alemanya)) ;
Boerwinkle, Eric (University of Texas Health Science Center at Houston (Estats Units d'Amèrica)) ;
Buring, Julie (Brigham and Women's Hospital (Boston, Estats Units d'Amèrica)) ;
Crisponi, Laura (Institute of Genetics and Biomedical Research (Sardinia, Itàlia)) ;
Easton, Douglas F. (University of Cambridge. Centre for Cancer Genetic Epidemiology) ;
Hayward, Caroline (University of Edinburgh. Institute of Genetics and Molecular Medicine (Gran Bretanya)) ;
Hu, Frank B. (Harvard Medical School (Boston, Estats Units d'Amèrica)) ;
Liu, Simin (Brown University. Departments of Epidemiology and Medicine (Providence, Estats Units d'Amèrica)) ;
Metspalu, Andres (University of Tartu. Estonian Genome Center (Estònia)) ;
Pennell, Craig E. (University of Western Australia. School of Women's and Infants' Health (Crawley, Austràlia)) ;
Ridker, Paul M. (Brigham and Women's Hospital (Boston, Estats Units d'Amèrica)) ;
Strauch, Konstantin (German Research Center for Environmental Health (Germany)) ;
Streeten, Elizabeth A. (University of Maryland School of Medicine (Estats Units d'Amèrica)) ;
Toniolo, Daniela (San Raffaele Scientific Institute (Milà, Itàlia)) ;
Uitterlinden, André G. (Erasmus University Rotterdam) ;
Ulivi, Sheila (Institute for Maternal and Child Health (Trieste, Itàlia)) ;
Völzke, Henry (University Medicine Greifswald (Alemanya)) ;
Wareham, Nicholas J. (University of Cambridge. School of Clinical Medicine (Gran Bretanya)) ;
Wellons, Melissa (Vanderbilt University Medical Center (Nashville, Estats Units d'Amèrica)) ;
Franceschini, Nora (University of North Carolina (Estats Units d'Amèrica). Department of Epidemiology) ;
Chasman, Daniel I. (Brigham and Women's Hospital (Boston, Estats Units d'Amèrica)) ;
Thorsteinsdottir, Unnur (deCODE Genetics (Reykjavík, Islàndia)) ;
Murray, Anna (University of Exeter. Medical School (Gran Bretanya)) ;
Stefánsson, Kári (deCODE Genetics (Reykjavík, Islàndia)) ;
Murabito, Joanne M. (National Heart, Lung, and Blood Institute (Framingham, Estats Units d'Amèrica)) ;
Ong, Ken K. (University of Cambridge. School of Clinical Medicine (Gran Bretanya)) ;
Perry, John R. B. (University of Cambridge. School of Clinical Medicine (Gran Bretanya))
More than 100 loci have been identified for age at menarche by genome-wide association studies; however, collectively these explain only ∼3% of the trait variance. Here we test two overlooked sources of variation in 192,974 European ancestry women: low-frequency protein-coding variants and X-chromosome variants. [...]
2015 - 10.1038/ncomms8756
Nature communications, Vol. 4 Núm. 6 (august 2015)
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