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21 p, 965.2 KB CSF progranulin increases in the course of Alzheimer's disease and is associated with sTREM2, neurodegeneration and cognitive decline / Suárez-Calvet, Marc (Ludwig-Maximilians-Universität München) ; Capell, Anja (Ludwig-Maximilians-Universität München) ; Araque Caballero, Miguel Ángel (Ludwig-Maximilians-Universität München) ; Morenas-Rodríguez, Estrella (Universitat Autònoma de Barcelona) ; Fellerer, Katrin (Ludwig-Maximilians-Universität München) ; Franzmeier, Nicolai (Ludwig-Maximilians-Universität München) ; Kleinberger, Gernot (Munich Cluster for Systems Neurology (SyNergy)) ; Eren, Erden (Dokuz Eylul University, Turkey) ; Deming, Yuetiva (Washington University School of Medicine) ; Piccio, Laura (Washington University School of Medicine) ; Karch, Celeste M. (Washington University School of Medicine) ; Cruchaga, Carlos (Washington University School of Medicine) ; Paumier, Katrina (Washington University School of Medicine) ; Bateman, Randall J. (Washington University School of Medicine) ; Fagan, Anne M. (Washington University School of Medicine) ; Morris, John C. (Washington University School of Medicine) ; Levin, Johannes (Ludwig-Maximilians-Universität München) ; Danek, Adrian (Ludwig-Maximilians-Universität München) ; Jucker, Mathias (University of Tübingen) ; Masters, Colin L. (University of Melbourne) ; Rossor, Martin N. (UCL Institute of Neurology (Regne Unit)) ; Ringman, John M. (University of Southern California) ; Shaw, Leslie M. (University of Pennsylvania) ; Trojanowski, John Q.. (University of Pennsylvania) ; Weiner, Michael (University of California at San Francisco) ; Ewers, Michael (Ludwig-Maximilians-Universität München) ; Haass, Christian (Munich Cluster for Systems Neurology (SyNergy))
Progranulin (PGRN) is predominantly expressed by microglia in the brain, and genetic and experimental evidence suggests a critical role in Alzheimer's disease (AD). We asked whether expression is changed in a disease severity-specific manner in . [...]
2018 - 10.15252/emmm.201809712
EMBO Molecular Medicine, Vol. 10 (november 2018)  
Registre complet - Creative Commons

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