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1.
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14 p, 902.2 KB |
Attention-deficit/hyperactivity disorder is associated with increased risk of cardiovascular diseases : A systematic review and meta-analysis
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Li, Lin (Karolinska Institutet (Estocolm, Suècia)) ;
Garcia-Argibay, Miguel (Örebro University) ;
Du Rietz, Ebba (Karolinska Institutet (Estocolm, Suècia)) ;
Brikell, Isabell (Aarhus University) ;
Solmi, Marco (University of Southampton) ;
Cortese, Samuele (University of Nottingham) ;
Ramos-Quiroga, Josep Antoni (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Ribasés Haro, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Chang, Zheng (Karolinska Institutet (Estocolm, Suècia)) ;
Larsson, Henrik (Karolinska Institutet (Estocolm, Suècia)) ;
Yao, Honghui (Karolinska Institutet (Estocolm, Suècia)) ;
Zhang, Le (Karolinska Institutet (Estocolm, Suècia)) ;
Universitat Autònoma de Barcelona
Attention-deficit/hyperactivity disorder (ADHD) often co-occurs with other psychiatric and physical diseases. However, available evidence on associations between ADHD and cardiovascular diseases (CVDs) is mixed. [...]
2023 -  10.1002/jcv2.12158
JCPP Advances, Vol. 3 (april 2023)
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2.
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10 p, 1.9 MB |
Shared genetic architecture between attention-deficit/hyperactivity disorder and lifespan
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Vilar-Ribó, L (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Cabana-Domínguez, Judit (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Martorell, Lourdes (Universitat Rovira i Virgili) ;
Ramos-Quiroga, Josep Antoni (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Sanchez-Roige, Sandra (Vanderbilt University Medical Center) ;
Palmer, Abraham A. (Vanderbilt University Medical Center) ;
Vilella, Elisabet (Hospital Universitari Institut Pere Mata) ;
Ribasés Haro, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Muntané, Gerard (Universitat Pompeu Fabra) ;
Soler Artigas, María (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona
There is evidence linking ADHD to a reduced life expectancy. The mortality rate in individuals with ADHD is twice that of the general population and it is associated with several factors, such as unhealthy lifestyle behaviors, social adversity, and mental health problems that may in turn increase mortality rates. [...]
2023 - 10.1038/s41386-023-01555-x
Neuropsychopharmacology, Vol. 48 (march 2023) , p. 981-990
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3.
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9 p, 2.7 MB |
Genetic association study of childhood aggression across raters, instruments, and age
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Ip, Hill F. (Vrije Universiteit Amsterdam) ;
van der Laan, Camiel M. (Netherlands Institute for the Study of Crime and Law Enforcement) ;
Krapohl, Eva M. L. (King's College London) ;
Brikell, Isabell (Karolinska Institutet (Estocolm, Suècia)) ;
Sánchez-Mora, Cristina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Nolte, Ilja M. (University of Groningen) ;
Pourcain, Beate St (Radboud University) ;
Bolhuis, Koen (Erasmus University Medical Center) ;
Palviainen, Teemu (University of Helsinki) ;
Zafarmand, Hadi (University of Amsterdam) ;
Colodro-Conde, Lucía (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ;
Gordon, Scott D (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ;
Zayats, Tetyana (Stanley Center for Psychiatric Research) ;
Aliev, Fazil (Karabuk University) ;
Jiang, Chang (University of Florida) ;
Wang, Carol A. (The University of Newcastle) ;
Saunders, Gretchen (University of Minnesota) ;
Karhunen, Ville (Imperial College London) ;
Hammerschlag, Anke R. (Amsterdam Public Health Research Institute) ;
Adkins, Daniel E. (University of Utah) ;
Border, Richard (University of Colorado Boulder) ;
Peterson, Roseann E. (Virginia Commonwealth University) ;
Prinz, Joseph A. (Duke University) ;
Thiering, Elisabeth (Ludwig-Maximilians-University of Munich) ;
Seppälä, Ilkka (Tampere University) ;
Vilor-Tejedor, Natàlia (Fundació Pasqual Maragall (FPM)) ;
Ahluwalia, Tarunveer Singh (Steno Diabetes Center Copenhagen) ;
Day, Felix R. (University of Cambridge School of Clinical Medicine) ;
Hottenga, Jouke Jan (Vrije Universiteit Amsterdam) ;
Allegrini, Andrea G. (King's College London) ;
Rimfeld, Kaili (King's College London) ;
Chen, Qi (Karolinska Institutet (Estocolm, Suècia)) ;
Lu, Yi (Karolinska Institutet (Estocolm, Suècia)) ;
Martin, Joanna (Cardiff University) ;
Soler Artigas, María (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Rovira, Paula (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Bosch, Rosa (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Español-Martín, Gemma (Hospital Universitari Vall d'Hebron) ;
Ramos-Quiroga, Josep Antoni (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Neumann, Alexander (Jewish General Hospital) ;
Ensink, Judith (De Bascule, Academic Centre for Child and Adolescent Psychiatry) ;
Grasby, Katrina (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ;
Morosoli, José J. (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ;
Tong, Xiaoran (University of Florida) ;
Marrington, Shelby (The University of Queensland) ;
Middeldorp, Christel (Children's Health Queensland Hospital) ;
Scott, James G. (Queensland Centre for Mental Health Research) ;
Vinkhuyzen, Anna (University of Queensland) ;
Shabalin, Andrey A. (University of Utah) ;
Corley, Robin (University of Colorado Boulder) ;
Evans, Luke M. (University of Colorado Boulder) ;
Sugden, Karen (Duke University) ;
Alemany, Sílvia (Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Sass, Lærke (University of Copenhagen) ;
Vinding, Rebecca (University of Copenhagen) ;
Ruth, Kate (University of Exeter Medical School) ;
Tyrrell, Jess (University of Exeter Medical School) ;
Davies, Gareth E. (Avera Institute for Human Genetics) ;
Ehli, Erik A. (Avera Institute for Human Genetics) ;
Hagenbeek, Fiona A. (Vrije Universiteit Amsterdam) ;
De Zeeuw, Eveline (Vrije Universiteit Amsterdam) ;
Van Beijsterveldt, Toos C.E.M. (Vrije Universiteit Amsterdam) ;
Larsson, Henrik (Orebro University) ;
Snieder, Harold (University of Groningen) ;
Verhulst, Frank C. (Copenhagen University Hospital) ;
Amin, Najaf (Erasmus University Medical Center) ;
Whipp, Alyce M. (University of Helsinki) ;
Korhonen, Tellervo (University of Helsinki) ;
Vuoksimaa, Eero (University of Helsinki) ;
Rose, Richard J. (Indiana University) ;
Uitterlinden, André G. (Netherlands Genomics Initiative (NGI)) ;
Heath, Andrew C. (Washington University) ;
Madden, Pamela (Washington University) ;
Haavik, Jan (Haukeland University Hospital (Bergen, Noruega)) ;
Harris, Jennifer R. (The Norwegian Institute of Public Health) ;
Helgeland, Øyvind (The Norwegian Institute of Public Health) ;
Johansson, Stefan E (University of Bergen) ;
Knudsen, Gun Peggy S. (The Norwegian Institute of Public Health) ;
Njolstad, Pal Rasmus (University of Bergen) ;
Lu, Qing (University of Florida) ;
Rodriguez, Alina (University of Lincoln) ;
Henders, Anjali K. (University of Queensland) ;
Mamun, Abdullah (University of Queensland) ;
Najman, Jackob M. (The University of Queensland) ;
Brown, Sandy (University of California) ;
Hopfer, Christian (University of Colorado School of Medicine) ;
Krauter, Kenneth (University of Colorado Boulder) ;
Reynolds, Chandra (University of California Riverside) ;
Smolen, Andrew (University of Colorado Boulder) ;
Stallings, Michael (University of Colorado Boulder) ;
Wadsworth, Sally (University of Colorado Boulder) ;
Wall, Tamara L. (University of California) ;
Silberg, Judy L. (Virginia Commonwealth University) ;
Miller, Allison (University of Otago Christchurch) ;
Keltikangas-Järvinen, Liisa (University of Helsinki) ;
Hakulinen, Christian (University of Helsinki) ;
Pulkki-Råback, Laura (University of Helsinki) ;
Havdahl, Alexandra (Norwegian Institute of Public Health) ;
Magnus, Per (Norwegian Institute of Public Health) ;
Raitakari, Olli T. (Turku University Hospital) ;
Perry, John R. B. (University of Cambridge School of Clinical Medicine) ;
Llop, Sabrina (Consorcio de Investigación Biomédica en Red de Epidemiología y Salud Pública) ;
Lopez-Espinosa, Maria-Jose (Universitat de València) ;
Bønnelykke, Klaus (University of Copenhagen) ;
Bisgaard, Hans (University of Copenhagen) ;
Sunyer Deu, Jordi (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Lehtimäki, Terho (Tampere University) ;
Arseneault, Louise (Duke University School of Medicine) ;
Standl, Marie (Helmholtz Zentrum München) ;
Heinrich, Joachim (University of Melbourne) ;
Boden, Joseph (University of Otago Christchurch) ;
Pearson, John (University of Otago Christchurch) ;
Horwood, L. John (University of Otago Christchurch) ;
Kennedy, Martin (University of Otago Christchurch) ;
Poulton, Richie (University of Otago) ;
Eaves, Lindon J. (Virginia Institute for Psychiatric and Behavioral Genetics) ;
Maes, Hermine H. (Virginia Commonwealth University) ;
Hewitt, John (University of Colorado Boulder) ;
Copeland, William E. (University of Vermont) ;
Costello, Elizabeth J. (Duke University) ;
Williams, Gail M. (The University of Queensland) ;
Wray, Naomi R (University of Queensland) ;
Järvelin, Marjo-Riitta (University of Oulu) ;
McGue, Matt (University of Minnesota) ;
Iacono, William (University of Minnesota) ;
Caspi, Avshalom (King's College London) ;
Moffitt, Terrie E. (King's College London) ;
Whitehouse, Andrew (The University of Western Australia) ;
Pennell, Craig E. (The University of Newcastle) ;
Klump, Kelly L. (Michigan State University) ;
Burt, S. Alexandra (Michigan State University) ;
Dick, Danielle M. (Virginia Commonwealth University) ;
Reichborn-Kjennerud, Ted (University of Oslo) ;
Martin, Nicholas G (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ;
Medland, Sarah Elizabeth (QIMR Berghofer Medical Research Institute (Brisbane, Austràlia)) ;
Vrijkotte, Tanja (University of Amsterdam) ;
Kaprio, Jaakko (University of Helsinki) ;
Tiemeier, Henning (Harvard TH Chan School of Public Health) ;
Smith, George Davey (University of Bristol) ;
Hartman, Catharina A. (University of Groningen) ;
Oldehinkel, Albertine J (University of Groningen) ;
Casas Brugué, Miquel (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Ribasés Haro, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Lichtenstein, Paul (Karolinska Institutet (Estocolm, Suècia)) ;
Lundström, Sebastian (University of Gothenburg) ;
Plomin, Robert (King's College London) ;
Bartels, Meike (Amsterdam Public Health Research Institute) ;
Nivard, Michel G. (Vrije Universiteit Amsterdam) ;
Boomsma, Dorret I (Amsterdam Public Health Research Institute)
Childhood aggressive behavior (AGG) has a substantial heritability of around 50%. Here we present a genome-wide association meta-analysis (GWAMA) of childhood AGG, in which all phenotype measures across childhood ages from multiple assessors were included. [...]
2021 - 10.1038/s41398-021-01480-x
Translational psychiatry, Vol. 11 (july 2021)
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33 p, 892.7 KB |
Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors
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Mullins, Niamh ;
Kang, JooEun ;
Campos, Adrian I. ;
Coleman, Jonathan R.I. ;
Edwards, Alexis C. ;
Galfalvy, Hanga ;
Levey, Daniel F. ;
Lori, Adriana ;
Shabalin, Andrey ;
Starnawska, Anna ;
Su, Mei-Hsin ;
Watson, Hunna J. ;
Adams, Mark ;
Awasthi, Swapnil ;
Gandal, Michael ;
Hafferty, Jonathan D. ;
Hishimoto, Akitoyo ;
Kim, Minsoo ;
Okazaki, Satoshi ;
Otsuka, Ikuo ;
Ripke, Stephan ;
Ware, Erin B. ;
Bergen, Andrew W. ;
Berrettini, Wade H. ;
Bohus, Martin ;
Brandt, Harry ;
Chang, Xiao ;
Chen, Wei J. ;
Chen, Hsi-Chung ;
Crawford, Steven ;
Crow, Scott ;
DiBlasi, Emily ;
Duriez, Philibert ;
Fernández-Aranda, Fernando (Hospital Universitari de Bellvitge) ;
Fichter, Manfred M. ;
Gallinger, Steven ;
Glatt, Stephen J. ;
Gorwood, Philip ;
Guo, Yiran ;
Hakonarson, Hakon ;
Halmi, Katherine A. ;
Hwu, Hai-Gwo ;
Jain, Sonia ;
Jamain, Stéphane ;
Jiménez-Murcia, Susana (Hospital Universitari de Bellvitge) ;
Johnson, Craig ;
Kaplan, Allan S. ;
Kaye, Walter H. ;
Keel, Pamela K. ;
Kennedy, James L. ;
Klump, Kelly L. ;
Li, Dong (Children's Hospital of Philadelphia (Pennsilvània)) ;
Liao, Shih-Cheng ;
Lieb, Klaus ;
Lilenfeld, Lisa ;
Liu, Chih-Min ;
Magistretti, Pierre J. ;
Marshall, Christian R. ;
Mitchell, James E. ;
Monson, Eric T. ;
Myers, Richard M. ;
Pinto, Dalila ;
Powers, Abigail ;
Ramoz, Nicolas ;
Roepke, Stefan ;
Rozanov, Vsevolod ;
Scherer, Stephen W. ;
Schmahl, Christian ;
Sokolowski, Marcus ;
Strober, Michael ;
Thornton, Laura M. ;
Treasure, Janet ;
Tsuang, Ming T. ;
Witt, Stephanie H. ;
Woodside, D. Blake ;
Yilmaz, Zeynep ;
Zillich, Lea ;
Adolfsson, Rolf ;
Agartz, Ingrid ;
Air, Tracy M. ;
Alda, Martin ;
Alfredsson, Lars ;
Andreassen, Ole A. ;
Anjorin, Adebayo ;
Appadurai, Vivek ;
Soler Artigas, María (Hospital Universitari Vall d'Hebron) ;
Van der Auwera, Sandra ;
Azevedo, M. Helena ;
Bass, Nicholas ;
Bau, Claiton Henrique Dotto ;
Baune, Bernhard T. ;
Bellivier, Frank ;
Berger, Klaus ;
Biernacka, Joanna M. ;
Bigdeli, Tim B. ;
Binder, Elisabeth B. ;
Boehnke, Michael ;
Boks, Marco P. ;
Bosch, Rosa (Hospital Universitari Vall d'Hebron) ;
Braff, David L. ;
Bryant, Richard ;
Budde, Monika ;
Byrne, Enda M. ;
Cahn, Wiepke ;
Casas Brugué, Miquel (Hospital Universitari Vall d'Hebron) ;
Castelao, Enrique ;
Cervilla, Jorge A. ;
Chaumette, Boris ;
Cichon, Sven ;
Corvin, Aiden ;
Craddock, Nicholas ;
Craig, David ;
Degenhardt, Franziska ;
Djurovic, Srdjan ;
Edenberg, Howard J. ;
Fanous, Ayman H. ;
Foo, Jerome C. ;
Forstner, Andreas J. ;
Frye, Mark ;
Fullerton, Janice M. ;
Gatt, Justine M. ;
Gejman, Pablo V. ;
Giegling, Ina ;
Grabe, Hans J. ;
Green, Melissa J. ;
Grevet, Eugenio H. ;
Grigoroiu-Serbanescu, Maria ;
Gutierrez, Blanca ;
Guzman-Parra, Jose ;
Hamilton, Steven P. ;
Hamshere, Marian L. ;
Hartmann, Annette ;
Hauser, Joanna ;
Heilmann-Heimbach, Stefanie ;
Hoffmann, Per ;
Ising, Marcus ;
Jones, Ian ;
Jones, Lisa A. ;
Jonsson, Lina ;
Kahn, René S. ;
Kelsoe, John R. ;
Kendler, Kenneth S. ;
Kloiber, Stefan ;
Koenen, Karestan C. ;
Kogevinas, M ;
Konte, Bettina ;
Krebs, Marie-Odile ;
Landén, Mikael ;
Lawrence, Jacob ;
Leboyer, Marion ;
Lee, Phil H. ;
Levinson, Douglas F. ;
Liao, Calwing ;
Lissowska, Jolanta ;
Lucae, Susanne ;
Mayoral-Cleries, Fermín ;
McElroy, Susan L. ;
McGrath, Patrick ;
McGuffin, Peter ;
McQuillin, Andrew ;
Medland, Sarah E. ;
Mehta, Divya ;
Melle, Ingrid ;
Milaneschi, Yuri ;
Mitchell, Philip B. ;
Molina, Esther ;
Morken, Gunnar ;
Bo Mortensen, Preben ;
Müller-Myhsok, Bertram ;
Nievergelt, Caroline ;
Nimgaonkar, Vishwajit ;
Nöthen, Markus M. ;
O'Donovan, Michael C. (Cardiff University) ;
Ophoff, Roel A. ;
Owen, Michael J. ;
Pato, Carlos ;
Pato, Michele T. ;
Penninx, Brenda WJH ;
Pimm, Jonathan ;
Pistis, Giorgio ;
Potash, James B. ;
Power, Robert A. ;
Preisig, Martin ;
Quested, Digby ;
Ramos-Quiroga, Josep Antoni (Hospital Universitari Vall d'Hebron) ;
Reif, Andreas ;
Ribasés Haro, Marta (Hospital Universitari Vall d'Hebron) ;
Richarte, Vanesa (Hospital Universitari Vall d'Hebron) ;
Rietschel, Marcella ;
Rivera, Margarita ;
Roberts, Andrea ;
Roberts, Gloria ;
Rouleau, Guy A. ;
Rovaris, Diego L. ;
Rujescu, Dan ;
Sánchez-Mora, Cristina (Hospital Universitari Vall d'Hebron) ;
Sanders, Alan R. ;
Schofield, Peter R. ;
Schulze, Thomas G. ;
Scott, Laura J. ;
Serretti, Alessandro ;
Shi, Jianxin ;
Shyn, Stanley I. ;
Sirignano, Lea ;
Sklar, Pamela ;
Smeland, Olav B. ;
Smoller, Jordan W. ;
Sonuga-Barke, Edmund J.S. ;
Spalletta, Gianfranco ;
Strauss, John S. ;
Świątkowska, Beata ;
Trzaskowski, Maciej ;
Turecki, Gustavo ;
Vilar-Ribó, L (Hospital Universitari Vall d'Hebron) ;
Vincent, John B. ;
Völzke, Henry ;
Walters, James T.R. ;
Weickert, Cynthia Shannon ;
Weickert, Thomas W. ;
Weissman, Myrna M. ;
Williams, Leanne M. ;
Wray, Naomi R. ;
Zai, Clement C. ;
Ashley-Koch, Allison E. ;
Beckham, Jean C. ;
Hauser, Elizabeth R. ;
Hauser, Michael A. ;
Kimbrel, Nathan A. ;
Lindquist, Jennifer H. ;
McMahon, Benjamin ;
Oslin, David W. ;
Qin, Xuejun ;
Agerbo, Esben ;
Børglum, Anders D. ;
Breen, Gerome ;
Erlangsen, Annette ;
Esko, Tõnu ;
Gelernter, Joel ;
Hougaard, David M. ;
Kessler, Ronald C. ;
Kranzler, Henry R. ;
Li, Qingqin S. ;
Martin, Nicholas G. ;
McIntosh, Andrew M. ;
Mors, Ole ;
Nordentoft, Merete ;
Olsen, Catherine M. ;
Porteous, David ;
Ursano, Robert J. ;
Wasserman, Danuta ;
Werge, Thomas ;
Whiteman, David C. ;
Bulik, Cynthia M. ;
Coon, Hilary ;
Demontis, Ditte ;
Docherty, Anna R. ;
Kuo, Po-Hsiu ;
Lewis, Cathryn M. ;
Mann, J. John ;
Rentería, Miguel E. ;
Smith, Daniel J. ;
Stahl, Eli A. ;
Stein, Murray B. ;
Streit, Fabian ;
Willour, Virginia ;
Ruderfer, Douglas M. ;
Universitat Autònoma de Barcelona
Suicide is a leading cause of death worldwide, and nonfatal suicide attempts, which occur far more frequently, are a major source of disability and social and economic burden. Both have substantial genetic etiology, which is partially shared and partially distinct from that of related psychiatric disorders. [...]
2021 - 10.1016/j.biopsych.2021.05.029
Biological psychiatry, Vol. 91 (september 2021) , p. 313-327
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17 p, 621.6 KB |
Mendelian randomization analysis for attention deficit/hyperactivity disorder : studying a broad range of exposures and outcomes
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Soler Artigas, María (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Sánchez-Mora, Cristina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Rovira, Paula (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Vilar-Ribó, L (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Ramos-Quiroga, Josep Antoni (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Ribasés Haro, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Universitat Autònoma de Barcelona
Attention deficit/hyperactivity disorder (ADHD) is a highly prevalent neurodevelopmental disorder caused by a combination of genetic and environmental factors and is often thought as an entry point into a negative life trajectory, including risk for comorbid disorders, poor educational achievement or low income. [...]
2022 - 10.1093/ije/dyac128
International journal of epidemiology, Vol. 52 (june 2022) , p. 386-402
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6.
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16 p, 2.1 MB |
Genome-wide multi-trait analysis of irritable bowel syndrome and related mental conditions identifies 38 new independent variants
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Alemany, Sílvia (Hospital Universitari Vall d'Hebron) ;
Soler Artigas, María (Hospital Universitari Vall d'Hebron) ;
Cabana-Domínguez, Judit (Hospital Universitari Vall d'Hebron) ;
Fakhreddine, Dana (Hospital Universitari Vall d'Hebron) ;
Llonga, Natalia (Hospital Universitari Vall d'Hebron) ;
Vilar-Ribó, L (Hospital Universitari Vall d'Hebron) ;
Rodríguez-Urrutia, Amanda (Hospital Universitari Vall d'Hebron) ;
Palacio, Judit (Hospital Universitari Vall d'Hebron) ;
González Castro, Ana Maria (Hospital Universitari Vall d'Hebron) ;
Lobo Álvarez, Beatriz (Hospital Universitari Vall d'Hebron) ;
Alonso Cotoner, Carmen (Hospital Universitari Vall d'Hebron) ;
Simrén, Magnus (University of North Carolina) ;
Santos, Javier (Hospital Universitari Vall d'Hebron) ;
Ramos-Quiroga, Josep Antoni (Hospital Universitari Vall d'Hebron) ;
Ribasés Haro, Marta (Hospital Universitari Vall d'Hebron) ;
Universitat Autònoma de Barcelona
Irritable bowel syndrome (IBS) is a chronic disorder of gut-brain interaction frequently accompanied by mental conditions, including depression and anxiety. Despite showing substantial heritability and being partly determined by a genetic component, the genetic underpinnings explaining the high rates of comorbidity remain largely unclear and there are no conclusive data on the temporal relationship between them. [...]
2023 - 10.1186/s12967-023-04107-5
Journal of translational medicine, Vol. 21 (april 2023)
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7.
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9 p, 262.4 KB |
Polygenic association between attention-deficit/hyperactivity disorder liability and cognitive impairments
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Vainieri, Isabella (Institute of Psychiatry (Regne Unit)) ;
Martin, Joanna (Cardiff University (Regne Unit)) ;
Rommel, Anna-Sophie (Public Health at the Icahn School of Medicine at Mount Sinai) ;
Asherson, Philip (King's College London) ;
Banaschewski, Tobias (University of Heidelberg) ;
Buitelaar, Jan (Radboud University Medical Centre) ;
Cormand, Bru (Institut de Recerca Sant Joan de Déu) ;
Crosbie, Jennifer (University of Toronto) ;
Faraone, Stephen V. (SUNY Upstate Medical University) ;
Franke, Barbara (Radboud University Medical Center) ;
Loo, Sandra K. (Semel Institute for Neuroscience and Human Behavior and David Geffen School of Medicine at UCLA) ;
Miranda, Ana (Universitat de València) ;
Manor, Iris (Tel-Aviv University) ;
Oades, Robert D. (University of Duisburg-Essen) ;
Purves, Kirstin L. (Institute of Psychiatry, Psychology and Neuroscience) ;
Ramos-Quiroga, Josep Antoni (Universitat Autònoma de Barcelona) ;
Ribasés Haro, Marta (Universitat de Barcelona) ;
Roeyers, Herbert (Ghent University) ;
Rothenberger, Aribert (University Medical Center Göttingen) ;
Schachar, Russell (University of Toronto) ;
Sergeant, Joseph (Vrije Universiteit) ;
Steinhausen, Hans-Christoph (Centre of Child and Adolescent Mental Health) ;
Vuijk, Pieter J. (Massachusetts General Hospital (Estats Units d'Amèrica)) ;
Doyle, Alysa E. (Harvard Medical School) ;
Kuntsi, Jonna (King's College London. Institute of Psychiatry, Psychology & Neuroscience)
A recent genome-wide association study (GWAS) identified 12 independent loci significantly associated with attention-deficit/hyperactivity disorder (ADHD). Polygenic risk scores (PRS), derived from the GWAS, can be used to assess genetic overlap between ADHD and other traits. [...]
2022 - 10.1017/S0033291720005218
Psychological Medicine, Vol. 52 (october 2022) , p. 3150-3158
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17 p, 693.0 KB |
Contribution of Common Genetic Variants to Risk of Early-Onset Ischemic Stroke
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Jaworek, Thomas ;
Xu, Huichun ;
Gaynor, Brady ;
Cole, John W. ;
Rannikmae, Kristiina ;
Stanne, Tara M. ;
Tomppo, Liisa ;
Abedi, Vida ;
Amouyel, Philippe ;
Armstrong, Nicole D. ;
Attia, John ;
Bell, Steven ;
Benavente, Oscar R. ;
Boncoraglio, Giorgio B. ;
Butterworth, Adam ;
Cárcel-Márquez, Jara (Institut d'Investigació Biomèdica Sant Pau) ;
Chen, Zhengming ;
Chong, Michael ;
Cruchaga, Carlos ;
Cushman, Mary ;
Danesh, John ;
Debette, Stéphanie ;
Duggan, David J. ;
Durda, Jon Peter ;
Engstrom, Gunnar ;
Enzinger, Chris ;
Faul, Jessica D. ;
Fecteau, Natalie S. ;
Fernandez-Cadenas, Israel (Institut d'Investigació Biomèdica Sant Pau) ;
Gieger, Christian ;
Giese, Anne-Katrin ;
Grewal, Raji P. ;
Grittner, Ulrike ;
Havulinna, Aki S. ;
Heitsch, Laura ;
Hochberg, Marc C. ;
Holliday, Elizabeth ;
Hu, Jie ;
Ilinca, Andreea ;
Irvin, Marguerite R. ;
Jackson, Rebecca D. ;
Jacob, Mina A. ;
Rabionet, Raquel ;
Jimenez-Conde, Jordi (Institut Hospital del Mar d'Investigacions Mèdiques) ;
Johnson, Julie A. ;
Kamatani, Yoichiro ;
Kardia, Sharon L.R. ;
Koido, Masaru ;
Kubo, Michiaki ;
Lange, Leslie ;
Lee, Jin-Moo ;
Lemmens, Robin ;
Levi, Christopher R. ;
Li, Jiang ;
Li, Liming ;
Lin, Kuang ;
Lopez, Haley ;
Luke, Sothear ;
Maguire, Jane ;
McArdle, Patrick F. ;
McDonough, Caitrin W. ;
Meschia, James F. (Mayo Clinic (Jacksonville, Estats Units d'Amèrica)) ;
Metso, Tiina ;
Müller-Nurasyid, Martina ;
Dichgans, Martin ;
O'Donnell, Martin ;
Peddareddygari, Leema R. ;
Pera, Joanna ;
Perry, James A. ;
Peters, Annette ;
Putaala, Jukka ;
Ray, Debashree ;
Rexrode, Kathryn ;
Ribasés Haro, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Rosand, Jonathan ;
Rothwell, Peter M. ;
Rundek, Tatjana ;
Ryan, Kathleen A. ;
Sacco, Ralph L. ;
Salomaa, Veikko ;
Sánchez-Mora, Cristina (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Schmidt, Reinhold ;
Sharma, Pankaj ;
Slowik, Agnieszka ;
Smith, Jennifer A. ;
Smith, Nicholas L. ;
Wassertheil-Smoller, Sylvia ;
Söderholm, Martin ;
Stine, O. Colin ;
Strbian, Daniel ;
Sudlow, Cathie L.M. ;
Tatlisumak, Turgut ;
Terao, Chikashi ;
Thijs, Vincent ;
Torres-Aguila, Nuria P.. ;
Trégouët, David-Alexandre ;
Tuladhar, Anil M. ;
Veldink, Jan ;
Walters, Robin G. ;
Weir, David R. ;
Woo, Daniel ;
Worrall, Bradford B. ;
Hong, Charles C. ;
Ross, Owen A. ;
Zand, Ramin ;
de Leeuw, Frank-Erik ;
Lindgren, Arne G. ;
Paré, Guillaume ;
Anderson, Christopher D. ;
Markus, Hugh S. ;
Jern, Christina ;
Malik, Rainer ;
Dichgans, Martin ;
Mitchell, Braxton D. ;
Kittner, Steven J. ;
Universitat Autònoma de Barcelona
Current genome-wide association studies of ischemic stroke have focused primarily on late-onset disease. As a complement to these studies, we sought to identify the contribution of common genetic variants to risk of early-onset ischemic stroke. [...]
2022 - 10.1212/WNL.0000000000201006
Neurology, Vol. 99 (october 2022) , p. e1738-e1754
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9 p, 1.2 MB |
Comprehensive analysis of omics data identifies relevant gene networks for Attention-Deficit/Hyperactivity Disorder (ADHD)
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Cabana-Domínguez, Judit (Universitat de Barcelona. Departament de Genètica, Microbiologia i Estadística) ;
Soler Artigas, María (Universitat de Barcelona. Departament de Genètica, Microbiologia i Estadística) ;
Arribas, Lorena (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Alemany, Sílvia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Vilar-Ribó, L (Centro de Investigación Biomédica en Red de Salud Mental) ;
Llonga, Natalia (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Fadeuilhe, Christian (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Corrales, Montserrat (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Richarte, Vanesa (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Ramos-Quiroga, Josep Antoni (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Ribasés Haro, Marta (Universitat de Barcelona. Departament de Genètica, Microbiologia i Estadística)
Attention-deficit/hyperactivity disorder (ADHD) is a highly prevalent neurodevelopmental disorder that results from the interaction of both genetic and environmental risk factors. Genome-wide association studies have started to identify multiple genetic risk loci associated with ADHD, however, the exact causal genes and biological mechanisms remain largely unknown. [...]
2022 - 10.1038/s41398-022-02182-8
Translational psychiatry, Vol. 12 (september 2022)
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Changes in the Mental Health of Children and Adolescents during the COVID-19 Lockdown : Associated Factors and Life Conditions
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Bosch, Rosa (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ;
Pagerols, Mireia (Hospital Sant Joan de Déu (Manresa)) ;
Prat, Raquel (Hospital Sant Joan de Déu (Manresa)) ;
Español-Martín, Gemma (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Rivas, Cristina (Hospital Sant Joan de Déu (Manresa)) ;
Dolz, Montserrat (Hospital Sant Joan de Déu (Manresa)) ;
Haro Abad, Josep Maria (Hospital Sant Joan de Déu (Manresa)) ;
Ramos-Quiroga, Josep Antoni (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Ribasés Haro, Marta (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Casas Brugué, Miquel (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal)
This study investigated the psychological impact of the coronavirus disease 2019 (COVID-19) among youth by analyzing their emotional/behavioral problems before and during the long-lasting lockdown in Spain. [...]
2022 - 10.3390/ijerph19074120
International journal of environmental research and public health, Vol. 19 (march 2022)
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