Dipòsit Digital de Documents de la UAB 7 registres trobats  La cerca s'ha fet en 0.00 segons. 
1.
11 p, 2.3 MB Pain in Older Adults With Dementia : A Survey in Spain / Gimenez-Llort, Lydia (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ; Bernal, Maria Luisa (Instituto de Investigación Sanitaria de Aragón) ; Docking, Rachael (Abertay University, Dundee, United Kingdom) ; Muntsant-Soria, Aida (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Torres-Lista, Virginia (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Bulbena Vilarrasa, Antonio (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ; Schofield, Patricia A. (Sheffield Hallam University, Sheffield, United Kingdom)
The risk of suffering pain increases significantly throughout life, reaching the highest levels in its latest years. Prevalence of pain in nursing homes is estimated to range from 40 to 80% of residents, most of them old adults affected with dementia. [...]
2020 - 10.3389/fneur.2020.592366
Frontiers in neurology, Vol. 11 (november 2020)  
2.
9 p, 1.4 MB Social Nesting, Animal Welfare, and Disease Monitoring / Gimenez-Llort, Lydia (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Torres-Lista, Virginia (Universitat Autònoma de Barcelona. Institut de Neurociències)
The assessment of welfare and disease progression in animal models is critical. Most tools rely on evaluating individual subjects, whereas social behaviors, also sensitive to acute illness, chronic diseases, or mental health, are scarcely monitored because they are complex and time-consuming. [...]
2021 - 10.3390/ani11041079
Animals, Vol. 11 Núm. 4 (2021) , p. 1079  
3.
9 p, 306.3 KB Vibrating Tail, Digging, Body/Face Interaction, and Lack of Barbering : Sex-Dependent Behavioral Signatures of Social Dysfunction in 3xTg-AD Mice as Compared to Mice with Normal Aging / Torres-Lista, Virginia (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Gimenez-Llort, Lydia (Universitat Autònoma de Barcelona. Institut de Neurociències)
Modeling of Alzheimer's disease (AD), classically focused on the subject-environment interaction, foresees current social neuroscience efforts as improving the predictive validity of new strategies. Here we studied social functioning among congeners in 13-14-month-old mice with normal aging in naturalistic and experimental conditions and depicted behavioral signatures of dysfunction in age-matched 3xTg-AD mice. [...]
2019 - 10.3233/JAD-190253
Journal of Alzheimer's disease, Vol. 69 (june 2019) , p. 969-977  
4.
25 p, 6.5 MB Impact of chronic risperidone use on behavior and survival of 3xTg-AD mice model of Alzheimer's disease and mice with normal aging / Torres-Lista, V. (Universitat Autònoma de Barcelona. Institut de Neurociències.) ; López-Pousa, S. (Institut d'Assistència Sanitaria. Research Unit and UVaMiD (Memory and Dementia Assessment Unit).) ; Gimenez-Llort, Lydia (Universitat Autònoma de Barcelona. Institut de Neurociències.)
Psychosis and/or aggression are common problems in dementia, and when severe or persistent, cause considerable patient distress and disability, caregiver stress, and early institutionalization. In 2005, the Food and Drug Administration (FDA) determined that atypical antipsychotics were associated with a significantly greater mortality risk compared to placebo, which prompted the addition of an FDA black-box warning. [...]
2019 - 10.3389/fphar.2019.01061
Frontiers in Pharmacology, Vol. 10 Núm. SEP (2019) , p. 1061  
5.
11 p, 334.7 KB Survival curves and behavioral profiles of female 3xTg-AD mice surviving to 18-months of age as compared to mice with normal aging / Torres-Lista, Virginia (Universitat Autònoma de Barcelona. Institut de Neurociències) ; De la Fuente, Mónica (Universidad Complutense de Madrid. Departamento de Fisiología) ; Gimenez-Llort, Lydia (Universitat Autònoma de Barcelona. Institut de Neurociències)
New evidence reveals a high degree of heterogeneity in Alzheimer's disease (AD) clinical and temporal patterns, supporting the existence of several subgroups of patients. Prognosticators of end-of-life dementia specific to elderly patients are necessary to address this heterogeneity. [...]
2017 - 10.3233/ADR-170011
Journal of Alzheimer's disease reports, Vol. 1, issue 1 (2017) , p. 47-57  
6.
15 p, 1.8 MB Secreted and Transmembrane αKlotho Isoforms Have Different Spatio-Temporal Profiles in the Brain during Aging and Alzheimer's Disease Progression / Massó Chacón, Anna (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Sánchez, Angela (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Gimenez-Llort, Lydia (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Lizcano de Vega, José Miguel (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Cañete Ríos, Manuel (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; García, Belen (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Torres-Lista, Virginia (Universitat Autònoma de Barcelona. Institut de Neurociències) ; Puig Ferrer, Meritxell (Universitat Autònoma de Barcelona. Centre de Biotecnologia Animal i de Teràpia Gènica (CBATEG)) ; Bosch i Merino, Assumpció (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Chillón Rodríguez, Miguel (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular)
The Klotho protein is a β-glucuronidase, and its overexpression is associated with life extension. Its mechanism of action is not fully understood, although it has been recently reported that αKlotho improves synaptic and cognitive functions, and it may also influence a variety of structures and functions during CNS maturation and aging. [...]
2015 - 10.1371/journal.pone.0143623
PloS one, Vol. 10, Num. 11 (November 2015) , p. 1-15  
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306 p, 7.6 MB Conducta social, anidación y respuesta a antipsicóticos atípicos en el modelo triple transgénico 3XTG-AD para la enfermedad de Alzheimer / Torres-Lista, Virginia ; Gimenez-Llort, Lydia, dir. (Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal) ; Universitat Autònoma de Barcelona. Departament de Psiquiatria i de Medicina Legal
A pesar de que la demencia es el síntoma característico de la enfermedad de Alzheimer, los síntomas conductuales y psicológicos asociados a ella (SCPD) y las alteraciones en las actividades de la vida diaria (AVD) son problemas comunes en los pacientes que sufren la enfermedad. [...]
Although dementia is the characteristic symptom of the Alzheimer's disease, Behavioral and Psychological Symptoms of Dementia (BPSD) and alterations in Daily Life Activities (DLA) are common problems in patients with the disease. [...]

Bellaterra : Universitat Autònoma de Barcelona, 2013  

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