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10 p, 5.0 MB |
Titanium-doped PET nanoplastics, from opaque milk bottle degradation, as a model of environmental true-to-life nanoplastics. Hazardous effects on Drosophila
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Alaraby, Mohamed (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Villacorta, Aliro (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Abass, Doaa (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Hernández, Alba (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Marcos Dauder, Ricardo (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Micro and nanoplastics (MNPLs) are emergent environmental pollutants, resulting from the degradation of plastic waste, requiring urgent information on their potential risks to human health. To determine such risks, reliable true-to-life materials are essential. [...]
2024 -  10.1016/j.envpol.2023.122968
Environmental Pollution, Vol. 341 (January 2024) , art. 122968
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15 p, 9.2 MB |
Morphologically different hydroxyapatite nanoparticles exert differential genotoxic effects in Drosophila
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Güneş, Merve (Akdeniz University. Department of Biology) ;
Yalçın, Burçin (Akdeniz University. Department of Biology) ;
Burgazlı, Ayşen Yağmur (Akdeniz University. Department of Biology) ;
Tagorti, Ghada (Akdeniz University. Department of Biology) ;
Yavuz, Emre (Akdeniz University. Department of Chemistry) ;
Akarsu, Esin (Akdeniz University. Department of Chemistry) ;
Kaya, Nuray (Akdeniz University. Department of Biology) ;
Marcos Dauder, Ricardo (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Kaya, Bülent (Akdeniz University. Department of Biology)
Hydroxyapatite (HAP) occurs naturally in sedimentary and metamorphic rocks and constitutes the hard structures in many organisms. Since synthetic nano-sized HAP (HAP-NPs) are used in orthopedic applications and for heavy metal remediation in aquatic and terrestrial media, both environment and humans are exposed to them. [...]
2023 - 10.1016/j.scitotenv.2023.166556
Science of the total environment, Vol. 904 (December 2023) , art. 166556
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189 p, 2.9 MB |
Deciphering the role of innate immune response in the model of tuberculosis in Drosophila melanogaster
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Arch Sisquella, Marta ;
Cardona, Pere-Joan, dir.
Actualment, s'estima que una tercera part de la població mundial està infectada per Mycobacterium tuberculosis (Mtb). Tot i això, només un petit percentatge desenvoluparà la malaltia activa. S'ha demostrat que aquesta progressió està relacionada amb una infiltració massiva neutròfils a les lesions infectades per Mtb i la posterior inducció d'una resposta immune de tipus Th17. [...]
Actualmente, se estima que una tercera parte de la población mundial está infectada por Mycobacterium tuberculosis (Mtb). Sin embargo, sólo un pequeño porcentaje desarrollará la enfermedad activa. [...]
Nowadays it is estimated that a third of the world population is infected with Mycobacterium tuberculosis (Mtb). However, just a reduced percentage will develop the active disease. It has been shown that this progression is related to massive neutrophil infiltration of lesions infected with Mtb and subsequent induction of a Th17 type immune response. [...]
2022
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12 p, 2.8 MB |
Antagonistic in vivo interaction of polystyrene nanoplastics and silver compounds. A study using Drosophila
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Alaraby, Mohamed (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Abass, Doaa (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Villacorta, Aliro (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Hernández Bonilla, Alba (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Marcos Dauder, Ricardo (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
Since heavy metals and micro−/nanoplastics (MNPLs) can share common environmental niches, their potential interactions could modulate their hazard impacts. The current study was planned to evaluate the potential interactions between silver compounds (silver nanoparticles or silver nitrate) and two different sizes of polystyrene nanoplastics (PSNPLs) (PS-50 and PS-500 nm), administered via ingestion to Drosophila larvae. [...]
2022 - 10.1016/j.scitotenv.2022.156923
Science of the total environment, Vol. 842 (October 2022) , art. 156923
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16 p, 1.4 MB |
Natural variation in genome architecture among 205 Drosophila melanogaster Genetic Reference Panel lines
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Huang, W. (North Carolina State University. Department of Biological Sciences) ;
Massouras, A. (Ecole Polytechnique Fédérale de Lausanne. Institute of Bioengineering) ;
Inoue, Y. (Osaka University. Center for Education in Liberal Arts and Sciences) ;
Peiffer, J. (North Carolina State University. Department of Biological Sciences) ;
Ràmia Jesús, Miquel (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Tarone, A. M. (Texas AandM University. Department of Entomology) ;
Turlapati, L. (North Carolina State University. Department of Biological Sciences) ;
Zichner, T. (European Molecular Biology Laboratory) ;
Zhu, Dianhui (Baylor College of Medicine. Human Genome Sequencing Center) ;
Lyman, R. F. (North Carolina State University. Department of Biological Sciences) ;
Magwire, M. M. (North Carolina State University. Department of Biological Sciences) ;
Blankenburg, K. (Baylor College of Medicine. Human Genome Sequencing Center) ;
Carbone, M. A. (North Carolina State University. Department of Biological Sciences) ;
Chang, K. (Baylor College of Medicine. Human Genome Sequencing Center) ;
Ellis, L. L. (Texas AandM University. Department of Entomology) ;
Fernandez, S. (Baylor College of Medicine. Human Genome Sequencing Center) ;
Han, Y. (Baylor College of Medicine. Human Genome Sequencing Center) ;
Highnam, G. (Virginia Tech. Virginia Bioinformatics Institute) ;
Hjelmen, C. E. (Texas AandM University. Department of Entomology) ;
Jack, J. R. (North Carolina State University. Department of Biological Sciences) ;
Javaid, M. (Baylor College of Medicine. Human Genome Sequencing Center) ;
Jayaseelan, J. C (Baylor College of Medicine. Human Genome Sequencing Center) ;
Kalra, D. (Baylor College of Medicine. Human Genome Sequencing Center) ;
Lee, S. (Baylor College of Medicine. Human Genome Sequencing Center) ;
Lewis, Lora (Baylor College of Medicine. Human Genome Sequencing Center) ;
Munidasa, M. (Baylor College of Medicine. Human Genome Sequencing Center) ;
Ongeri, F. (Baylor College of Medicine. Human Genome Sequencing Center) ;
Patel, Shohba (Baylor College of Medicine. Human Genome Sequencing Center) ;
Perales, L. (Baylor College of Medicine. Human Genome Sequencing Center) ;
Perez, Agapito (Baylor College of Medicine. Human Genome Sequencing Center) ;
Pu, L. L. (Baylor College of Medicine. Human Genome Sequencing Center) ;
Rollmann, S. M. (North Carolina State University. Department of Biological Sciences) ;
Ruth, R. (Baylor College of Medicine. Human Genome Sequencing Center) ;
Saada, N. (Baylor College of Medicine. Human Genome Sequencing Center) ;
Warner, C. (Shell International Exploration and Production, Inc.) ;
Williams, A. (Baylor College of Medicine. Human Genome Sequencing Center) ;
Wu, Y. Q. (Baylor College of Medicine. Human Genome Sequencing Center) ;
Yamamoto, A. (North Carolina State University. Department of Biological Sciences) ;
Zhang, Yiqing (Baylor College of Medicine. Human Genome Sequencing Center) ;
Zhu, Y. (Baylor College of Medicine. Human Genome Sequencing Center) ;
Anholt, Robert R. H (North Carolina State University. Department of Biological Sciences) ;
Korbel, Jan O. (European Molecular Biology Laboratory) ;
Mittelman, D. (Virginia Tech. Virginia Bioinformatics Institute. Department of Biological Sciences) ;
Muzny, D. M. (Baylor College of Medicine. Human Genome Sequencing Centere) ;
Gibbs, R. A. (Baylor College of Medicine. Human Genome Sequencing Center) ;
Barbadilla Prados, Antonio (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ;
Johnston, J. S. (Texas AandM University. Department of Entomology) ;
Stone, E. A. (North Carolina State University. Department of Biological Sciences) ;
Richards, S. (Baylor College of Medicine. Human Genome Sequencing Center) ;
Deplancke, Bart (Swiss Institute of Bioinformatics) ;
MacKay, T. F. C (North Carolina State University. Department of Biological Sciences)
The Drosophila melanogaster Genetic Reference Panel (DGRP) is a community resource of 205 sequenced inbred lines, derived to improve our understanding of the effects of naturally occurring genetic variation on molecular and organismal phenotypes. [...]
2014 - 10.1101/gr.171546.113
Genome research, Vol. 24, issue 7 (July 2014) , p. 1193-1208
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6 p, 700.6 KB |
IMKT : the integrative McDonald and Kreitman test
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Murga-Moreno, Jesus (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Coronado-Zamora, Marta (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Hervás Fernández, Sergi (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Casillas Viladerrams, Sònia (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ;
Barbadilla Prados, Antonio (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia)
The McDonald and Kreitman test (MKT) is one of the most powerful and widely used methods to detect and quantify recurrent natural selection using DNA sequence data. Here we present iMKT (acronym for integrative McDonald and Kreitman test), a novel web-based service performing four distinct MKT types. [...]
2019 - 10.1093/nar/gkz372
Nucleic acids research, Vol. 47, issue W1 (Jan. 2019) , p. W283-W288
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