Baselga, J. - Resultats de la cerca - Dipòsit Digital de Documents de la UAB

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11.

132 p, 3.3 MB

Development and validation of predictive model for identification of MLH1 and MSH2 mutation carriers in Lynch syndrome / Balmaña Gelpí, Judith ; Brunet, Joan (dir.) ; Baselga Torres, Josep, 1959-2021, dir. (Hospital Universitari Vall d'Hebron) ; Universitat Autònoma de Barcelona. Departament de Medicina
Lynch syndrome is the most frequent hereditary colorectal cancer syndrome. It is estimated to account for 1-3% of all colorectal cancer patients and endometrial cancer patients14. Many studies have been published to attempt to address the prevalence of this syndrome and the heterogeneity is huge, mostly because population-based studies are few, geographical distribution of carriers may differ due to founder mutations, or studies may include testing of different type of mismatch repair (MMR) genes15-28. [...]
Bellaterra : Universitat Autònoma de Barcelona, 2010

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12.

80 p, 310.3 KB

Telomerasa : regulación, diana terapéutica y significado clínico en neoplasias humanas / Albanell Mestres, Joan ; Baselga Torres, Josep, 1959-2021, dir. (Hospital Universitari Vall d'Hebron) ; Moore, Malcolm A. S., dir.
Las células malignas deben adquirir un potencial de replicación ilimitado (inmortalidad celular) para la formación de tumores avanzados. La adquisición de inmortalidad celular depende de la reactivación de la telomerasa, una enzima que permite compensar el problema de replicación terminal del ADN asociado a cada división celular. [...]
Malignant cells have to acquire a limitless replicative potential (immortality) to be able to form an advanced tumor. The acquisition of cellular imortality is linked to the reactivation of telomerase, an enzyme that has the potential to overcome the DNA end replication problem that occurs during each round of cell división. [...]
Bellaterra : Universitat Autònoma de Barcelona, 2002

3 documents

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Vegeu també: autors amb noms similars
1	Baselga, JM.
1	Baselga, Javier

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