Dipòsit Digital de Documents de la UAB 84 registres trobats  anterior11 - 20següentfinal  anar al registre: La cerca s'ha fet en 0.01 segons. 
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13 p, 1.4 MB An improved secretion signal enhances the secretion of model proteins from Pichia pastoris / Barrero, Juan J. (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental) ; Casler, Jason C. (University of Chicago. Department of Molecular Genetics and Cell Biology) ; Valero Barranco, Francisco (Universitat Autònoma de Barcelona. Departament d'Enginyeria Quimica, Biològica i Ambiental) ; Ferrer, Pau (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental) ; Glick, Benjamin S. (University of Chicago. Department of Molecular Genetics and Cell Biology)
Background: proteins can be secreted from a host organism with the aid of N-terminal secretion signals. The budding yeast Pichia pastoris (Komagataella sp. ) is widely employed to secrete proteins of academic and industrial interest. [...]
2018 - 10.1186/s12934-018-1009-5
Microbial cell factories, Vol. 17 (2018) , art. 161  
12.
42 p, 7.3 MB Combinatorial regulation of stilbene synthase genes by WRKY and MYB transcription factors in grapevine (Vitis vinifera L.) / Vannozzi, Alessandro (Università di Padova. Dipartimento di Agronomia, Animali, Alimenti, Risorse naturali e Ambiente) ; Wong, Darren Chern Jan (The Australian National University. Research School of Biology) ; Höll, Janine (Universität Heidelberg. Centre for Organismal Studies) ; Hmma, Ibrahim (Università di Padova. Dipartimento di Agronomia, Animali, Alimenti, Risorse naturali e Ambiente) ; Matus, José Tomás (Centre de Recerca en Agrigenòmica) ; Bogs, Jochen (Universität Heidelberg. Centre for Organismal Studies) ; Ziegler, Tobias (Universität Heidelberg. Centre for Organismal Studies) ; Dry, Ian (Commonwealth Scientific and Industrial Research Organisation (Australia)) ; Barcaccia, Gianni (Università di Padova. Dipartimento di Agronomia, Animali, Alimenti, Risorse naturali e Ambiente) ; Lucchin, Margherita (Università di Padova. Dipartimento di Agronomia, Animali, Alimenti, Risorse naturali e Ambiente)
Stilbene synthase (STS) is the key enzyme leading to the biosynthesis of resveratrol. Recently we reported two R2R3-MYB transcription factor (TF) genes that regulate the stilbene biosynthetic pathway in grapevine: VviMYB14 and VviMYB15. [...]
2018 - 10.1093/pcp/pcy045
Plant & cell physiology, Vol. 59, issue 5 (May 2018) , p. 1043-1059  
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13 p, 3.4 MB Human Pancreatic ß Cell lncRNAs Control Cell-Specific Regulatory Networks / Akerman, Ildem (Institut d'Investigacions Biomèdiques August Pi I Sunyer) ; Tu, Zhidong (Department of Genetics and Genomic Science, Icahn School of Medicine at Mount Sinai) ; Beucher, Anthony (Department of Medicine, Imperial College London) ; Rolando, Delphine M.Y. (Department of Medicine, Imperial College London) ; Sauty-Colace, Claire (Institut du cerveau et de la moelle. Hôpital Pitié-Salpêtrière) ; Benazra, Marion (Institut du cerveau et de la moelle. Hôpital Pitié-Salpêtrière) ; Nakic, Nikolina (Department of Medicine, Imperial College London) ; Yang, Jialiang (Department of Genetics and Genomic Science, Icahn School of Medicine at Mount Sinai) ; Wang, Huan (Department of Genetics and Genomic Science, Icahn School of Medicine at Mount Sinai) ; Pasquali, Lorenzo (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Moran, Ignasi (Department of Medicine, Imperial College London) ; Garcia Hurtado, Javier (Institut d'Investigacions Biomèdiques August Pi I Sunyer) ; Castro, Natalia (Institut d'Investigacions Biomèdiques August Pi I Sunyer) ; Gonzalez Franco, Roser (Department of Medicine, Imperial College London) ; Stewart, Andrew F. (Diabetes, Obesity, and Metabolism Institute, Icahn School of Medicine at Mount Sinai) ; Bonner, Caroline (European Genomic Institute for Diabetes) ; Piemonti, Lorenzo (Diabetes Research Institute (HSR-DRI), San Raffaele Scientific Institute) ; Berney, Thierry (Cell Isolation and Transplantation Center, University of Geneva,) ; Groop, Leif (Department of Clinical Sciences, Lund University Diabetes Centre) ; Kerr-Conte, Julie (European Genomic Institute for Diabetes) ; Pattou, Francois (European Genomic Institute for Diabetes) ; Argmann, Carmen (Department of Genetics and Genomic Science, Icahn School of Medicine at Mount Sinai) ; Schadt, Eric (Department of Genetics and Genomic Science, Icahn School of Medicine at Mount Sinai) ; Ravassard, Phillipe (Institut du cerveau et de la moelle. Hôpital Pitié-Salpêtrière) ; Jorge Ferrer (Institut d'Investigacions Biomèdiques August Pi i Sunyer) ; Universitat Autònoma de Barcelona
Recent studies have uncovered thousands of long non-coding RNAs (lncRNAs) in human pancreatic ß cells. ß cell lncRNAs are often cell type specific and exhibit dynamic regulation during differentiation or upon changing glucose concentrations. [...]
2017 - 10.1016/j.cmet.2016.11.016
Cell metabolism, Vol. 25 (february 2017) , p. 400-411  
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12 p, 3.1 MB Survivin, a key player in cancer progression, increases in obesity and protects adipose tissue stem cells from apoptosis / Ejarque, Miriam (Hospital Universitari de Tarragona Joan XXIII, Institut d'Investigació Sanitària Pere Virgili) ; Ceperuelo Mallafré, Victòria (Hospital Universitari de Tarragona Joan XXIII, Institut d'Investigació Sanitària Pere Virgili) ; Serena, Carolina (Hospital Universitari de Tarragona Joan XXIII, Institut d'Investigació Sanitària Pere Virgili) ; Pachón, Gisela (CIBER de Diabetes y Enfermedades Metabólicas Asociadas, Instituto de Salud Carlos III, Madrid) ; Núñez Álvarez, Yaiza (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Terrón Puig, Margarida (Hospital Universitari de Tarragona Joan XXIII, Institut d'Investigació Sanitària Pere Virgili) ; Calvo, Enrique (Hospital Universitari de Tarragona Joan XXIII, Institut d'Investigació Sanitària Pere Virgili) ; Núñez Roa, Catalina (Hospital Universitari de Tarragona Joan XXIII, Institut d'Investigació Sanitària Pere Virgili) ; Oliva Olivera, Wilfredo (CIBER de la Fisiopatología de la Obesidad y la Nutrición, Instituto de Salud Carlos III, Madrid) ; Tinahones, Francisco J (CIBER de la Fisiopatología de la Obesidad y la Nutrición, Instituto de Salud Carlos III, Madrid) ; Peinado, Miguel Angel (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Vendrell, Joan (Hospital Universitari de Tarragona Joan XXIII, Institut d'Investigació Sanitària Pere Virgili) ; Fernández Veledo, Sonia (Hospital Universitari de Tarragona Joan XXIII, Institut d'Investigació Sanitària Pere Virgili) ; Universitat Autònoma de Barcelona
Adipose tissue (AT) has a central role in obesity-related metabolic imbalance through the dysregulated production of cytokines and adipokines. In addition to its known risk for cardiovascular disease and diabetes, obesity is also a major risk for cancer. [...]
2017 - 10.1038/cddis.2017.209
Cell Death and Disease, Núm. 8 (2017) , p. 1-12  
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16 p, 4.9 MB The Nuclear Receptor LXR Limits Bacterial Infection of Host Macrophages through a Mechanism that Impacts Cellular NAD Metabolism / Matalonga, Jonathan (Universitat de Barcelona. Departament de Biologia Cel·lular, Fisiologia i Immunologia) ; Glaria, Estibaliz (Universitat de Barcelona. Departament de Biologia Cel·lular, Fisiologia i Immunologia) ; Bresque, Mariana (Institut Pasteur Montevideo) ; Escande, Carlos (Institut Pasteur Montevideo) ; Carbó, José María (Universitat de Barcelona. Departament de Biologia Cel·lular, Fisiologia i Immunologia) ; Kiefer, Kerstin (Universitat Pompeu Fabra. Departament de Ciències experimentals i de la Salut) ; Vicente, Ruben (Universitat Pompeu Fabra. Departament de Ciències experimentals i de la Salut) ; León, Theresa E. (Universitat de Barcelona. Departament de Biologia Cel·lular, Fisiologia i Immunologia) ; Beceiro, Susana (Instituto de Investigaciones Biomédicas "Alberto Sols" de Madrid) ; Pascual-García, Mónica (Universitat de Barcelona. Departament de Biologia Cel·lular, Fisiologia i Immunologia) ; Serret, Joan (Parc Científic de Barcelona) ; Sanjurjo, Lucía (Institut Germans Trias i Pujol) ; Morón-Ros,Samantha (Universitat de Barcelona. Departament de Biologia Cel·lular, Fisiologia i Immunologia) ; Riera, Antoni (IRB Barcelona) ; Paytubi, Sonia (Universitat de Barcelona. Departament de Química Orgànica) ; Antonio Juarez,Antonio (Universitat de Barcelona. Departament de Química Orgànica) ; Sotillo, Fernando (IRB Barcelona) ; Lindbom, Lennart (Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm) ; Caelles, Carme (Universitat de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Sarrias, Maria-Rosa (Institut Germans Trias i Pujol) ; Sancho, Jaime (Institute of Parasitology and Biomedicine "López-Neyra") ; Castrillo, Antonio (Instituto de Investigaciones Biomédicas "Alberto Sols" de Madrid) ; Chini ,Eduardo N. (Mayo Clinic College of Medicine) ; Valledor, Annabel F. (Universitat de Barcelona. Departament de Biologia Cel·lular, Fisiologia i Immunologia)
Macrophages exert potent effector functions against invading microorganisms but constitute, paradoxically, a preferential niche for many bacterial strains to replicate. Using a model of infection by Salmonella Typhimurium, we have identified a molecular mechanism regulated by the nuclear receptor LXR that limits infection of host macrophages through transcriptional activation of the multifunctional enzyme CD38. [...]
2017 - 10.1016/j.celrep.2017.01.007
Cell reports, Vol. 18, Issue 5 (January 2017) , p. 1241-1255  
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47 p, 1.4 MB The circadian clock sets the time of DNA replication licensing to regulate growth in Arabidopsis / Fung, Jorge (Centre de Recerca en Agrigenòmica) ; Lee, Kyounghee (Sungkyunkwan University. Department of Biological Sciences) ; Seo, Pil Joon (Sungkyunkwan University. Department of Biological Sciences) ; Polyn, Stefanie (Universiteit Gent. Department of Plant Biotechnology and Bioinformatics) ; De Veylder, Lieven (Universiteit Gent. Department of Plant Biotechnology and Bioinformatics) ; Mas, Paloma (Centre de Recerca en Agrigenòmica)
The circadian clock and cell cycle as separate pathways have been well documented in plants. Elucidating whether these two oscillators are connected is critical for understanding plant growth. We found that a slow-running circadian clock decelerates the cell cycle and, conversely, a fast clock speeds it up. [...]
2018 - 10.1016/j.devcel.2018.02.022
Developmental Cell, Vol. 45, issue 1 (April 2018) , p. 101-113  
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14 p, 1.9 MB Low doses of LPS exacerbate the inflammatory response and trigger death on TLR3-primed human monocytes / Monguió Tortajada, Marta (Institut Germans Trias i Pujol) ; Franquesa, Marcella (Institut Germans Trias i Pujol) ; Sarrias, Maria-Rosa (Network for Biomedical Research in Hepatic and Digestive Diseases (CIBERehd)) ; Borràs, Francesc E. (Institut Germans Trias i Pujol) ; Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia
TLR sensing of pathogens triggers monocyte activation to initiate the host innate immune response to infection. Monocytes can dynamically adapt to different TLR agonists inducing different patterns of inflammatory response, and the sequence of exposure to TLRs can dramatically modulate cell activation. [...]
2018 - 10.1038/s41419-018-0520-2
Cell death and disease, Vol. 9 (May 2018) , art. 499  
18.
13 p, 1.7 MB Metabolic flux analysis and the NAD(P)H/NAD(P) + ratios in chemostat cultures of Azotobacter vinelandii / García, Andres (Universidad Autónoma de México. Instituto de Biotecnologia) ; Ferrer, Pau (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental) ; Albiol i Sala, Joan (Universitat Autònoma de Barcelona. Departament d'Enginyeria Química, Biològica i Ambiental) ; Castillo, Tania (Universidad Autónoma de México. Instituto de Biotecnologia) ; Segura, Daniel (Universidad Nacional Autònoma de México. Instituto de Biotecnologia) ; Peña, Carlos (Universidad Autónoma de México. Instituto de Biotecnologia)
Azotobacter vinelandii is a bacterium that produces alginate and polyhydroxybutyrate (P3HB); however, the role of NAD(P)H/NAD(P) + ratios on the metabolic fluxes through biosynthesis pathways of these biopolymers remains unknown. [...]
2018 - 10.1186/s12934-018-0860-8
Microbial cell factories, Vol. 17 (January 2018) , art. 10  
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69 p, 2.7 MB Water potential regulation, stomatal behaviour and hydraulic transport under drought : deconstructing the iso/anisohydric concept / Martínez Vilalta, Jordi, 1975- (Centre de Recerca Ecològica i Aplicacions Forestals) ; García Forner, Núria (Centre de Recerca Ecològica i Aplicacions Forestals)
In this review, we address the relationship between stomatal behaviour, water potential regulation and hydraulic transport in plants, focusing on the implications for the iso/anisohydric classification of plant drought responses at seasonal timescales. [...]
2017 - 10.1111/pce.12846
Plant, cell & environment, Vol. 40, issue 6 (June 2017) , p. 962-976  
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14 p, 1.9 MB Detailed Characterization of Mesenchymal Stem/Stromal Cells from a Large Cohort of AML Patients Demonstrates a Definitive Link to Treatment Outcomes / Diaz de la Guardia, Rafael (Centro de Investigación Biomédica en Red-Oncología (CIBERONC), ISCIII) ; Lopez-Millan, Belen (Centro de Investigación Biomédica en Red-Oncología (CIBERONC), ISCIII, Madrid) ; Lavoie, Jessie R. (Regulatory Research Division, Centre for Biologics Evaluation, Biologics and Genetic Therapies Directorate, Health Canada, Ottawa, ON K1A 0L2, Canada) ; Bueno, Clara (Centro de Investigación Biomédica en Red-Oncología (CIBERONC), ISCIII, Madrid) ; Castaño Cardoso, Julio (Centro de Investigación Biomédica en Red-Oncología (CIBERONC), ISCIII, Madrid) ; Gómez-Casares, Maite (Servicio de Hematología, Hospital Universitario de Gran Canaria Dr. Negrin, Las Palmas de Gran Canaria) ; Vives, Susana (Josep Carreras Leukemia Research Institute, Universitat Autònoma Barcelona) ; Palomo Sanchis, Laura (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ; Juan, Manel (Servicio de Inmunología, Hospital Clínico de Barcelona) ; Delgado, Julio (Servicio de Hematología, Hospital Clínico de Barcelona) ; Blanco, Maria L. (Institut d'Investigació Biomèdica Sant Pau) ; Nomdedeu, Josep (Institut d'Investigació Biomèdica Sant Pau) ; Chaparro, Alberto (Hematology Department, Hospital Clínico San Carlos, Universidad Complutense de Madrid) ; Fuster, Jose Luis (Sección de Oncohematología Pediátrica, Hospital Clínico Virgen de Arrixaca, Murcia) ; Anguita, Eduardo (Hematology Department, Hospital Clínico San Carlos, Universidad Complutense de Madrid) ; Rosu-Myles, Michael (Regulatory Research Division, Centre for Biologics Evaluation, Biologics and Genetic Therapies Directorate, Health Canada, Ottawa,Canada) ; Menéndez, Pablo (Instituciò Catalana de Recerca i Estudis Avançats (ICREA), Barcelona)
Bone marrow mesenchymal stem/stromal cells (BM-MSCs) are key components of the hematopoietic niche thought to have a direct role in leukemia pathogenesis. BM-MSCs from patients with acute myeloid leukemia (AML) have been poorly characterized due to disease heterogeneity. [...]
2017 - 10.1016/j.stemcr.2017.04.019
Stem cell reports, Vol. 8 (may 2017) , p. 1573-1586  

Dipòsit Digital de Documents de la UAB : 84 registres trobats   anterior11 - 20següentfinal  anar al registre:
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