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19 p, 2.4 MB |
Multi-phenotype analyses of hemostatic traits with cardiovascular events reveal novel genetic associations
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Temprano-Sagrera, Gerard (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Sitlani, C.M. (University of Washington) ;
Bone, W.P. (University of Pennsylvania) ;
Martin-Bornez, M. (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Voight, B.F. (University of Pennsylvania Perelman School of Medicine) ;
Morrison, A.C. ;
Damrauer, S.M. ;
de Vries, P.S. ;
Smith, N.L. ;
Sabater-Lleal, Maria (Institut d'Investigació Biomèdica Sant Pau) ;
Dehghan, A. ;
Heath, A.S. ;
Morrison, A.C. ;
Reiner, A.P. ;
Johnson, A. ;
Richmond, A. ;
Peters, A. ;
van Hylckama Vlieg, A. ;
McKnight, B. ;
Psaty, B.M. ;
Hayward, C. ;
Ward-Caviness, C. ;
O'Donnell, C. ;
Chasman, D. ;
Strachan, D.P. ;
Tregouet, D.A. ;
Mook-Kanamori, D. ;
Gill, D. ;
Thibord, F. ;
Asselbergs, F.W. ;
Leebeek, F.W.G. ;
Rosendaal, F.R. ;
Davies, G. ;
Homuth, G. ;
Temprano, G. ;
Campbell, H. ;
Taylor, H.A. ;
Bressler, J. ;
Huffman, J.E. ;
Rotter, J.I. ;
Yao, J. ;
Wilson, J.F. ;
Bis, J.C. ;
Hahn, J.M. ;
Desch, K.C. ;
Wiggins, K.L. ;
Raffield, L.M. ;
Bielak, L.F. ;
Yanek, L.R. ;
Kleber, M.E. ;
Mueller, M. ;
Kavousi, M. ;
Mangino, M. ;
Liu, M. ;
Brown, M.R. ;
Conomos, M.P. ;
Jhun, M.A. ;
Chen, M.H. ;
de Maat, M.P.M. ;
Pankratz, N. ;
Smith, N.L. ;
Peyser, P.A. ;
Elliot, P. ;
Wei, P. ;
Wild, P.S. ;
Morange, P.E. ;
van der Harst, P. ;
Yang, Q. ;
Le, N.Q. ;
Marioni, R. ;
Li, R. ;
Damrauer, S.M. ;
Cox, S.R. ;
Trompet, S. ;
Felix, S.B. ;
Völker, U. ;
Tang, W. ;
Koenig, W. ;
Jukema, J.W. ;
Guo, X. ;
Lindstrom, S. ;
Wang, L. ;
Smith, E.N. ;
Gordon, W. ;
van Hylckama Vlieg, A. ;
de Andrade, M. ;
Brody, J.A. ;
Pattee, J.W. ;
Haessler, J. ;
Brumpton, B.M. ;
Suchon, P. ;
Chen, M.H. ;
Turman, C. ;
Germain, M. ;
Wiggins, K.L. ;
MacDonald, J. ;
Braekkan, S.K. ;
Armasu, S.M. ;
Pankratz, N. ;
Jackson, R.D. ;
Nielsen, J.B. ;
Giulianini, F. ;
Puurunen, M.K. ;
Ibrahim, M. ;
Heckbert, S.R. ;
Bammler, T.K. ;
Frazer, K.A. ;
McCauley, B.M. ;
Taylor, K. ;
Pankow, James S ;
Reiner, A.P. ;
Gabrielsen, M.E. ;
Deleuze, J.F. ;
O'Donnell, C.J. ;
Kim, J. ;
McKnight, B. ;
Kraft, P. ;
Hansen, J.B. ;
Rosendaal, F.R. ;
Heit, J.A. ;
Psaty, B.M. ;
Tang, W. ;
Kooperberg, C. ;
Hveem, K. ;
Ridker, P.M. ;
Morange, P.E. ;
Johnson, A.D. ;
Kabrhel, C. ;
Trégouët, D.A. ;
Smith, N.L. ;
Malik, R. ;
Chauhan, G. ;
Traylor, M. ;
Sargurupremraj, M. ;
Okada, Y. ;
Mishra, A. ;
Rutten-Jacobs, L. ;
Giese, A.K. ;
van der Laan, S.W. ;
Gretarsdottir, S. ;
Anderson, C. D. ;
Chong, M. ;
Adams, H.H.H. ;
Ago, T. ;
Almgren, P. ;
Amouyel, P. ;
Ay, H. ;
Bartz, T.M. ;
Benavente, O.R. ;
Bevan, S. ;
Boncoraglio, G.B. ;
Brown, R.D. ;
Butterworth, A.S. ;
Carrera, C. ;
Carty, C.L. ;
Chen, W.M. ;
Cole, J.W. ;
Correa, A. ;
Cotlarciuc, I. ;
Cruchaga, C. ;
Danesh, J. ;
de Bakker, P.I.W. ;
DeStefano, A.L. ;
den Hoed, M. ;
Duan, Q. ;
Engelter, S.T. ;
Falcone, G.J. ;
Gottesman, R.F. ;
Grewal, R.P. ;
Gudnason, V. ;
Gustafsson, S. ;
Haessler, J. ;
Harris, T.B. ;
Hassan, A. ;
Havulinna, A.S. ;
Heckbert, S.R. ;
Holliday, E.G. ;
Howard, G. ;
Hsu, F.C. ;
Hyacinth, H.I. ;
Arfan Ikram, M. ;
Ingelsson, E. ;
Irvin, M.R. ;
Jian, X. ;
Jiménez-Conde, J. ;
Johnson, J.A. ;
Jukema, J.W. ;
Kanai, M. ;
Keene, K.L. ;
Kissela, B.M. ;
Kleindorfer, D.O. ;
Kooperberg, C. ;
Kubo, M. ;
Lange, L.A. ;
Langefeld, C.D. ;
Langenberg, C. ;
Launer, L.J. ;
Lee, J.M. ;
Lemmens, R. ;
Leys, D. ;
Lewis, C.M. ;
Lin, W.Y. ;
Lindgren, A.G. ;
Lorentzen, E. ;
Magnusson, P.K. ;
Maguire, J. ;
Manichaikul, A. ;
McArdle, P.F. ;
Meschia, J.F. ;
Mitchell, B.D. ;
Mosley, T.H. ;
Nalls, M.A. ;
Ninomiya, T. ;
O'Donnell, M.J. ;
Psaty, B.M. ;
Pulit, S.L. ;
Rannikmäe, K. ;
Reiner, A.P. ;
Rexrode, K.M. ;
Rice, K. ;
Rich, S.S. ;
Ridker, P.M. ;
Rost, N.S. ;
Rothwell, P.M. ;
Rotter, J.I. ;
Rundek, T. ;
Sacco, R.L. ;
Sakaue, S. ;
Sale, M.M. ;
Salomaa, V. ;
Sapkota, B.R. ;
Schmidt, R. ;
Schmidt, C.O. ;
Schminke, U. ;
Sharma, P. ;
Slowik, A. ;
Sudlow, C.L.M. ;
Tanislav, C. ;
Tatlisumak, T. ;
Taylor, K.D. ;
Thijs, V.N.S. ;
Thorleifsson, G. ;
Thorsteinsdottir, U. ;
Tiedt, S. ;
Trompet, S. ;
Tzourio, C. ;
van Duijn, C.M. ;
Walters, M. ;
Wareham, N.J. ;
Wassertheil-Smoller, S. ;
Wilson, J.G. ;
Wiggins, K.L. ;
Yang, Q. ;
Yusuf, S. ;
Amin, N. ;
Aparicio, H.S. ;
Arnett, D.K. ;
Attia, J. ;
Beiser, A.S. ;
Berr, C. ;
Buring, J.E. ;
Bustamante, M. ;
Caso, V. ;
Cheng, Y.C. ;
Hoan Choi, S. ;
Chowhan, A. ;
Cullell, N. ;
Dartigues, J.F. ;
Delavaran, H. ;
Delgado, P. ;
Dörr, M. ;
Engström, G. ;
Ford, I. ;
Gurpreet, W.S. ;
Hamsten, A. ;
Heitsch, L. ;
Hozawa, A. ;
Ibanez, L. ;
Ilinca, A. ;
Ingelsson, M. ;
Iwasaki, M. ;
Jackson, R.D. ;
Jood, K. ;
Jousilahti, P. ;
Kaffashian, S. ;
Kalra, L. ;
Kamouchi, M. ;
Kitazono, T. ;
Kjartansson, O. ;
Kloss, M. ;
Koudstaal, P.J. ;
Krupinski, J. ;
Labovitz, D.L. ;
Laurie, C.C. ;
Levi, C.R. ;
Li, L. ;
Lind, L. ;
Lindgren, C.M. ;
Lioutas, V. ;
Mei Liu, Y. ;
Lopez, O.L. ;
Makoto, H. ;
Martinez-Majander, N. ;
Matsuda, K. ;
Minegishi, N. ;
Montaner, J. ;
Morris, A.P. ;
Muiño, E. ;
Müller-Nurasyid, M. ;
Norrving, B. ;
Ogishima, S. ;
Parati, E.A. ;
Reddy Peddareddygari, L. ;
Pedersen, N.L. ;
Pera, J. ;
Perola, M. ;
Pezzini, A. ;
Pileggi, S. ;
Rabionet, R. ;
Riba-Llena, I. ;
Ribasés, M. ;
Romero, J.R. ;
Roquer, J. ;
Rudd, A.G. ;
Sarin, A.P. ;
Sarju, R. ;
Sarnowski, C. ;
Sasaki, M. ;
Satizabal, C.L. ;
Satoh, M. ;
Sattar, N. ;
Sawada, N. ;
Sibolt, G. ;
Sigurdsson, Á. ;
Smith, A. ;
Sobue, K. ;
Soriano-Tárraga, C. ;
Stanne, T. ;
Colin Stine, O. ;
Stott, D.J. ;
Strauch, K. ;
Takai, T. ;
Tanaka, H. ;
Tanno, K. ;
Teumer, A. ;
Tomppo, L. ;
Torres-Aguila, N.P. ;
Touze, E. ;
Tsugane, S. ;
Uitterlinden, A.G. ;
Valdimarsson, E.M. ;
van der Lee, S.J. ;
Völzke, H. ;
Wakai, K. ;
Weir, D. ;
Williams, S.R. ;
Wolfe, C.D.A. ;
Wong, Q. ;
Xu, H. ;
Yamaji, T. ;
Sanghera, D.K. ;
Melander, O. ;
Jern, C. ;
Strbian, D. ;
Fernandez-Cadenas, I. ;
Longstreth, W.T. ;
Rolfs, A. ;
Hata, J. ;
Woo, D. ;
Rosand, J. ;
Pare, G. ;
Hopewell, J.C. ;
Saleheen, D. ;
Stefansson, K. ;
Worrall, B.B. ;
Kittner, S.J. ;
Seshadri, S. ;
Fornage, M. ;
Markus, H. S. ;
Howson, J.M.M. ;
Kamatani, Y. ;
Debette, S. ;
Dichgans, M. ;
Universitat Autònoma de Barcelona
Multi-phenotype analysis of genetically correlated phenotypes can increase the statistical power to detect loci associated with multiple traits, leading to the discovery of novel loci. This is the first study to date to comprehensively analyze the shared genetic effects within different hemostatic traits, and between these and their associated disease outcomes. [...]
2022 -  10.1111/jth.15698
Journal of Thrombosis and Haemostasis, Vol. 20 Núm. 6 (01 2022) , p. 1331-1349
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12 p, 1.3 MB |
Gene-level association analysis of systemic sclerosis : A comparison of African-Americans and White populations
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Gorlova, Olga Y. (Dartmouth College) ;
Li, Yafang (Dartmouth College) ;
Gorlov, Ivan (Dartmouth College) ;
Ying, Jun (University of Texas McGovern Medical School) ;
Chen, Wei V. (UT MD Anderson Cancer Center) ;
Assassi, Shervin (University of Texas McGovern Medical School) ;
Reveille, John D. (University of Texas McGovern Medical School) ;
Arnett, Frank C. (University of Texas McGovern Medical School) ;
Zhou, Xiaodong (University of Texas McGovern Medical School) ;
Bossini-Castillo, Lara (Wellcome Trust Sanger Institute (Regne Unit)) ;
Lopez-Isac, Elena (Institute of Parasitology and Biomedicine López-Neyra) ;
Acosta-Herrera, Marialbert (Institute of Parasitology and Biomedicine López-Neyra) ;
Gregersen, Peter K. (Feinstein Institute for Medical Research) ;
Lee, Annette T. (Robert S. Feinstein Institute for Medical Research) ;
Steen, Virginia D. (Georgetown University Medical Center) ;
Fessler, Barri J. (University of Alabama-Birmingham) ;
Khanna, Dinesh (University of Michigan) ;
Schiopu, Elena (University of Michigan) ;
Silver, Richard M. (Medical University of South Carolina) ;
Molitor, Jerry A. (University of Minnesota) ;
Furst, Daniel E. (University of Florence) ;
Kafaja, Suzanne (University of California-Los Angeles) ;
Simms, Robert W. (Boston University) ;
Lafyatis, Robert A. (University of Pittsburgh) ;
Carreira, Patricia E (Hospital Universitario de Madrid) ;
Simeón-Aznar, Carmen Pilar (Hospital Universitari Vall d'Hebron) ;
Castellvi, Ivan (Institut d'Investigació Biomèdica Sant Pau) ;
Beltran, Emma (Hospital Universitari i Politècnic La Fe (València)) ;
Ortego, Norberto (University Hospital San Cecilio) ;
Amos, Christopher I. (Dartmouth College) ;
Martin, Javier (Institute of Parasitology and Biomedicine López-Neyra. IPBLN-CSIC) ;
Mayes, Maureen D. (University of Texas McGovern Medical School) ;
Universitat Autònoma de Barcelona
Gene-level analysis of ImmunoChip or genome-wide association studies (GWAS) data has not been previously reported for systemic sclerosis (SSc, scleroderma). The objective of this study was to analyze genetic susceptibility loci in SSc at the gene level and to determine if the detected associations were shared in African-American and White populations, using data from ImmunoChip and GWAS genotyping studies. [...]
2018 - 10.1371/journal.pone.0189498
PloS one, Vol. 13 Núm. 1 (january 2018) , p. e0189498
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17 p, 3.2 MB |
β2-adrenergic stimulation potentiates spontaneous calcium release by increasing signal mass and co-activation of ryanodine receptor clusters
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Nolla-Colomer, Carme (Universitat Politècnica de Catalunya. Department Automatic Control) ;
Casabella Ramón, Sergi (Institut d'Investigació Biomèdica Sant Pau) ;
Jiménez-Sábado, Verónica (Institut d'Investigació Biomèdica Sant Pau) ;
Vallmitjana, Alexander (Universitat Politècnica de Catalunya. Department Automatic Control) ;
Tarifa, Carmen (Institut d'Investigacions Biomèdiques de Barcelona) ;
Herraiz-Martínez, Adela (Institut d'Investigacions Biomèdiques de Barcelona) ;
Llach, Anna (IIB Sant Pau) ;
Taurón, Manel (Institut d'Investigació Biomèdica Sant Pau) ;
Montiel, José (Institut d'Investigació Biomèdica Sant Pau) ;
Cinca, J. (Universitat Autònoma de Barcelona) ;
Chen, S.R.W. (Department of Physiology and Pharmacology. University of Calgary) ;
Benitez, R. (Universitat Politècnica de Catalunya. Departament d'Enginyeria de Sistemes, Automàtica i Informàtica Industrial) ;
Hove-Madsen, Leif (Institut d'Investigació Biomèdica Sant Pau) ;
Universitat Autònoma de Barcelona
Aims: It is unknown how β-adrenergic stimulation affects calcium dynamics in individual RyR2 clusters and leads to the induction of spontaneous calcium waves. To address this, we analysed spontaneous calcium release events in green fluorescent protein (GFP)-tagged RyR2 clusters. [...]
2022 - 10.1111/apha.13736
Acta Physiologica, Vol. 234 Núm. 4 (april 2022) , p. e13736
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33 p, 892.7 KB |
Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors
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Mullins, Niamh ;
Kang, JooEun ;
Campos, Adrian I. ;
Coleman, Jonathan R.I. ;
Edwards, Alexis C. ;
Galfalvy, Hanga ;
Levey, Daniel F. ;
Lori, Adriana ;
Shabalin, Andrey ;
Starnawska, Anna ;
Su, Mei-Hsin ;
Watson, Hunna J. ;
Adams, Mark ;
Awasthi, Swapnil ;
Gandal, Michael ;
Hafferty, Jonathan D. ;
Hishimoto, Akitoyo ;
Kim, Minsoo ;
Okazaki, Satoshi ;
Otsuka, Ikuo ;
Ripke, Stephan ;
Ware, Erin B. ;
Bergen, Andrew W. ;
Berrettini, Wade H. ;
Bohus, Martin ;
Brandt, Harry ;
Chang, Xiao ;
Chen, Wei J. ;
Chen, Hsi-Chung ;
Crawford, Steven ;
Crow, Scott ;
DiBlasi, Emily ;
Duriez, Philibert ;
Fernández-Aranda, Fernando (Hospital Universitari de Bellvitge) ;
Fichter, Manfred M. ;
Gallinger, Steven ;
Glatt, Stephen J. ;
Gorwood, Philip ;
Guo, Yiran ;
Hakonarson, Hakon ;
Halmi, Katherine A. ;
Hwu, Hai-Gwo ;
Jain, Sonia ;
Jamain, Stéphane ;
Jiménez-Murcia, Susana (Hospital Universitari de Bellvitge) ;
Johnson, Craig ;
Kaplan, Allan S. ;
Kaye, Walter H. ;
Keel, Pamela K. ;
Kennedy, James L. ;
Klump, Kelly L. ;
Li, Dong (Children's Hospital of Philadelphia (Pennsilvània)) ;
Liao, Shih-Cheng ;
Lieb, Klaus ;
Lilenfeld, Lisa ;
Liu, Chih-Min ;
Magistretti, Pierre J. ;
Marshall, Christian R. ;
Mitchell, James E. ;
Monson, Eric T. ;
Myers, Richard M. ;
Pinto, Dalila ;
Powers, Abigail ;
Ramoz, Nicolas ;
Roepke, Stefan ;
Rozanov, Vsevolod ;
Scherer, Stephen W. ;
Schmahl, Christian ;
Sokolowski, Marcus ;
Strober, Michael ;
Thornton, Laura M. ;
Treasure, Janet ;
Tsuang, Ming T. ;
Witt, Stephanie H. ;
Woodside, D. Blake ;
Yilmaz, Zeynep ;
Zillich, Lea ;
Adolfsson, Rolf ;
Agartz, Ingrid ;
Air, Tracy M. ;
Alda, Martin ;
Alfredsson, Lars ;
Andreassen, Ole A. ;
Anjorin, Adebayo ;
Appadurai, Vivek ;
Soler Artigas, María (Hospital Universitari Vall d'Hebron) ;
Van der Auwera, Sandra ;
Azevedo, M. Helena ;
Bass, Nicholas ;
Bau, Claiton Henrique Dotto ;
Baune, Bernhard T. ;
Bellivier, Frank ;
Berger, Klaus ;
Biernacka, Joanna M. ;
Bigdeli, Tim B. ;
Binder, Elisabeth B. ;
Boehnke, Michael ;
Boks, Marco P. ;
Bosch, Rosa (Hospital Universitari Vall d'Hebron) ;
Braff, David L. ;
Bryant, Richard ;
Budde, Monika ;
Byrne, Enda M. ;
Cahn, Wiepke ;
Casas Brugué, Miquel (Hospital Universitari Vall d'Hebron) ;
Castelao, Enrique ;
Cervilla, Jorge A. ;
Chaumette, Boris ;
Cichon, Sven ;
Corvin, Aiden ;
Craddock, Nicholas ;
Craig, David ;
Degenhardt, Franziska ;
Djurovic, Srdjan ;
Edenberg, Howard J. ;
Fanous, Ayman H. ;
Foo, Jerome C. ;
Forstner, Andreas J. ;
Frye, Mark ;
Fullerton, Janice M. ;
Gatt, Justine M. ;
Gejman, Pablo V. ;
Giegling, Ina ;
Grabe, Hans J. ;
Green, Melissa J. ;
Grevet, Eugenio H. ;
Grigoroiu-Serbanescu, Maria ;
Gutierrez, Blanca ;
Guzman-Parra, Jose ;
Hamilton, Steven P. ;
Hamshere, Marian L. ;
Hartmann, Annette ;
Hauser, Joanna ;
Heilmann-Heimbach, Stefanie ;
Hoffmann, Per ;
Ising, Marcus ;
Jones, Ian ;
Jones, Lisa A. ;
Jonsson, Lina ;
Kahn, René S. ;
Kelsoe, John R. ;
Kendler, Kenneth S. ;
Kloiber, Stefan ;
Koenen, Karestan C. ;
Kogevinas, M ;
Konte, Bettina ;
Krebs, Marie-Odile ;
Landén, Mikael ;
Lawrence, Jacob ;
Leboyer, Marion ;
Lee, Phil H. ;
Levinson, Douglas F. ;
Liao, Calwing ;
Lissowska, Jolanta ;
Lucae, Susanne ;
Mayoral-Cleries, Fermín ;
McElroy, Susan L. ;
McGrath, Patrick ;
McGuffin, Peter ;
McQuillin, Andrew ;
Medland, Sarah E. ;
Mehta, Divya ;
Melle, Ingrid ;
Milaneschi, Yuri ;
Mitchell, Philip B. ;
Molina, Esther ;
Morken, Gunnar ;
Bo Mortensen, Preben ;
Müller-Myhsok, Bertram ;
Nievergelt, Caroline ;
Nimgaonkar, Vishwajit ;
Nöthen, Markus M. ;
O'Donovan, Michael C. (Cardiff University) ;
Ophoff, Roel A. ;
Owen, Michael J. ;
Pato, Carlos ;
Pato, Michele T. ;
Penninx, Brenda WJH ;
Pimm, Jonathan ;
Pistis, Giorgio ;
Potash, James B. ;
Power, Robert A. ;
Preisig, Martin ;
Quested, Digby ;
Ramos-Quiroga, Josep Antoni (Hospital Universitari Vall d'Hebron) ;
Reif, Andreas ;
Ribasés Haro, Marta (Hospital Universitari Vall d'Hebron) ;
Richarte, Vanesa (Hospital Universitari Vall d'Hebron) ;
Rietschel, Marcella ;
Rivera, Margarita ;
Roberts, Andrea ;
Roberts, Gloria ;
Rouleau, Guy A. ;
Rovaris, Diego L. ;
Rujescu, Dan ;
Sánchez-Mora, Cristina (Hospital Universitari Vall d'Hebron) ;
Sanders, Alan R. ;
Schofield, Peter R. ;
Schulze, Thomas G. ;
Scott, Laura J. ;
Serretti, Alessandro ;
Shi, Jianxin ;
Shyn, Stanley I. ;
Sirignano, Lea ;
Sklar, Pamela ;
Smeland, Olav B. ;
Smoller, Jordan W. ;
Sonuga-Barke, Edmund J.S. ;
Spalletta, Gianfranco ;
Strauss, John S. ;
Świątkowska, Beata ;
Trzaskowski, Maciej ;
Turecki, Gustavo ;
Vilar-Ribó, L (Hospital Universitari Vall d'Hebron) ;
Vincent, John B. ;
Völzke, Henry ;
Walters, James T.R. ;
Weickert, Cynthia Shannon ;
Weickert, Thomas W. ;
Weissman, Myrna M. ;
Williams, Leanne M. ;
Wray, Naomi R. ;
Zai, Clement C. ;
Ashley-Koch, Allison E. ;
Beckham, Jean C. ;
Hauser, Elizabeth R. ;
Hauser, Michael A. ;
Kimbrel, Nathan A. ;
Lindquist, Jennifer H. ;
McMahon, Benjamin ;
Oslin, David W. ;
Qin, Xuejun ;
Agerbo, Esben ;
Børglum, Anders D. ;
Breen, Gerome ;
Erlangsen, Annette ;
Esko, Tõnu ;
Gelernter, Joel ;
Hougaard, David M. ;
Kessler, Ronald C. ;
Kranzler, Henry R. ;
Li, Qingqin S. ;
Martin, Nicholas G. ;
McIntosh, Andrew M. ;
Mors, Ole ;
Nordentoft, Merete ;
Olsen, Catherine M. ;
Porteous, David ;
Ursano, Robert J. ;
Wasserman, Danuta ;
Werge, Thomas ;
Whiteman, David C. ;
Bulik, Cynthia M. ;
Coon, Hilary ;
Demontis, Ditte ;
Docherty, Anna R. ;
Kuo, Po-Hsiu ;
Lewis, Cathryn M. ;
Mann, J. John ;
Rentería, Miguel E. ;
Smith, Daniel J. ;
Stahl, Eli A. ;
Stein, Murray B. ;
Streit, Fabian ;
Willour, Virginia ;
Ruderfer, Douglas M. ;
Universitat Autònoma de Barcelona
Suicide is a leading cause of death worldwide, and nonfatal suicide attempts, which occur far more frequently, are a major source of disability and social and economic burden. Both have substantial genetic etiology, which is partially shared and partially distinct from that of related psychiatric disorders. [...]
2021 - 10.1016/j.biopsych.2021.05.029
Biological psychiatry, Vol. 91 (september 2021) , p. 313-327
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11 p, 519.8 KB |
Prevalence and clinical impact of alcohol withdrawal syndrome in alcohol-associated hepatitis and the potential role of prophylaxis : a multinational, retrospective cohort study
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Marti-Aguado, David (Institut d'Investigació Biomèdica (INCLIVA)) ;
Gougol, Amir (University of California) ;
Gomez-Medina, Concepcion (Institut d'Investigació Biomèdica (INCLIVA)) ;
Jamali, Arsia (University of Pittsburgh Medical Center) ;
Abo-Zed, Abdelrhman (University of Pittsburgh Medical Center) ;
Morales-Arraez, Dalia (Hospital Universitario de Canarias (La Laguna)) ;
Jimenez-Sosa, Alejandro (Hospital Universitario de Canarias (La Laguna)) ;
Burns, Keith (University of Pittsburgh Medical Center) ;
Bawa, Aditi (University of Pittsburgh Medical Center) ;
Hernández, Anjara (Hospital Universitario de Canarias (La Laguna)) ;
Pujol, Claudia (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Alvarado-Tapias, Edilmar (Institut d'Investigació Biomèdica Sant Pau) ;
Szafranska, Justyna (Institut d'Investigació Biomèdica Sant Pau) ;
Chiu, Wai Kan (University of Pittsburgh Medical Center) ;
Villagrasa, Ares (Hospital Universitari Vall d'Hebron) ;
Ventura-Cots, Meritxell (Hospital Universitari Vall d'Hebron) ;
Gandicheruvu, Haritha (University of Pittsburgh Medical Center) ;
Lluch, Paloma (Institut d'Investigació Biomèdica (INCLIVA)) ;
Chen, Hui-Wei (Allegheny General Hospital) ;
Rachakonda, Vikrant (University of California) ;
Duarte-Rojo, Andres (University of Pittsburgh Medical Center) ;
Bataller, Ramon (Hospital Clínic i Provincial de Barcelona) ;
Universitat Autònoma de Barcelona
The prevalence and impact of alcohol withdrawal syndrome (AWS) in patients with alcohol-associated hepatitis (AH) are unknown. In this study, we aimed to investigate the prevalence, predictors, management, and clinical impact of AWS in patients hospitalized with AH. [...]
2023 - 10.1016/j.eclinm.2023.102046
EClinicalMedicine, Vol. 61 (june 2023)
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6.
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14 p, 1.4 MB |
Comparative genomics reveals the hybrid origin of a macaque group
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Zhang, Baolin (Chinese Academy of Sciences) ;
Chen, Wu (Guangzhou Zoo and Guangzhou Wildlife Research Center) ;
Wang, Zefu (Sichuan University) ;
Pang, Wey (Chinese Academy of Sciences) ;
Luo, Meng-Ting (Chinese Academy of Sciences) ;
Wang, Sheng (Chinese Academy of Sciences) ;
Shao, Yong (Chinese Academy of Sciences) ;
He, Wen-Qiang (Chinese Academy of Sciences) ;
Deng, Yuan (University of Copenhagen) ;
Zhou, Long (Zhejiang University School of Medicine) ;
Chen, Jiawei (BGI-Shenzhen) ;
Yang, Min-Min (Chinese Academy of Sciences) ;
Wu, Yajiang (Guangzhou Zoo and Guangzhou Wildlife Research Center) ;
Wang, Lu (Northwest University) ;
Fernández-Bellon, Hugo (Zoo de Barcelona) ;
Molloy, Sandra (Dublin Zoo) ;
Meunier, Hélène (Université de Strasbourg) ;
Wanert, Fanélie (Université de Strasbourg) ;
Kuderna, Lukas (Illumina Inc) ;
Marques-Bonet, Tomas 1975- (Institut Català de Paleontologia Miquel Crusafont) ;
Roos, Christian (German Primate Center) ;
Qi, Xiao-Guang (Northwest University) ;
Li, Ming (Chinese Academy of Sciences) ;
Liu, Zhijin (Capital Normal University) ;
Schierup, Mikkel Heide (Aarhus University) ;
Cooper, David N. (Cardiff University) ;
Liu, Jianquan (Sichuan University) ;
Zheng, Yong-Tang (Chinese Academy of Sciences) ;
Zhang, Guojie (Zhejiang University Medical Cente) ;
Wu, Dong-Dong (Chinese Academy of Sciences)
Although species can arise through hybridization, compelling evidence for hybrid speciation has been reported only rarely in animals. Here, we present phylogenomic analyses on genomes from 12 macaque species and show that the fascicularis group originated from an ancient hybridization between the sinica and silenus groups ~3. [...]
2023 - 10.1126/sciadv.add3580
Science advances, Vol. 9, Issue 22 (June 2023) , art. eadd3580
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7.
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13 p, 2.9 MB |
Impact of R-Carvedilol on β2-Adrenergic Receptor-Mediated Spontaneous Calcium Release in Human Atrial Myocytes
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Casabella Ramón, Sergi (Institut d'Investigació Biomèdica Sant Pau) ;
Jiménez-Sábado, Verónica (Institut d'Investigació Biomèdica Sant Pau) ;
Tarifa, C. (Instituto de Investigaciones Biomédicas de Barcelona) ;
Casellas, Sandra (Institut d'Investigació Biomèdica Sant Pau) ;
Lu, T.T. (Faculty of Medicine. University of British Columbia) ;
Izquierdo-Castro, Paloma (Instituto de Investigaciones Biomédicas de Barcelona) ;
Gich, Ignasi (Institut d'Investigació Biomèdica Sant Pau) ;
Jiménez, M. (Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas) ;
Ginel, Antonino (Institut d'Investigació Biomèdica Sant Pau) ;
Guerra Ramos, José María (Institut d'Investigació Biomèdica Sant Pau) ;
Chen, S.R.W. (Department of Physiology and Pharmacology. Libin Cardiovascular Institute of Alberta. University of Calgary) ;
Benítez, Raúl (Universitat Politècnica de Catalunya. Departament d'Enginyeria de Sistemes, Automàtica i Informàtica Industrial) ;
Hove-Madsen, Leif (Institut d'Investigació Biomèdica Sant Pau) ;
Universitat Autònoma de Barcelona
A hallmark of atrial fibrillation is an excess of spontaneous calcium release events, which can be mimicked by β1- or β2-adrenergic stimulation. Because β1-adrenergic receptor blockers (β1-blockers) are primarily used in clinical practice, we here examined the impact of β2-adrenergic stimulation on spontaneous calcium release and assessed whether the R- and S-enantiomers of the non-selective β- blocker carvedilol could reverse these effects. [...]
2022 - 10.3390/biomedicines10071759
Biomedicines, Vol. 10 Núm. 7 (july 2022) , p. 1759
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8.
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12 p, 4.8 MB |
Global impact of COVID-19 on stroke care
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Nogueira, Raul G. (Grady Memorial Hospital) ;
Abdalkader, Mohamad (Boston Medical Center) ;
Qureshi, Muhammed M. (Boston Medical Center) ;
Frankel, Michael R. (Grady Memorial Hospital) ;
Mansour, Ossama Yassin (Alexandria University Hospital) ;
Yamagami, Hiroshi (Osaka National Hospital) ;
Qiu, Zhongming (Xinqiao Hospital of the Army Medical University) ;
Farhoudi, Mehdi (Tabriz University) ;
Siegler, James E (Cooper Neurological Institute) ;
Yaghi, Shadi (New York University School of Medicine) ;
Raz, Eytan (New York University School of Medicine) ;
Sakai, Nobuyuki (Kobe City Medical Center General Hospital) ;
Ohara, Nobuyuki (Kobe City Medical Center General Hospital) ;
Piotin, Michel (Fondation Ophtalmologique Adolphe de Rothschild) ;
Mechtouff, Laura (Hospices Civils de Lyon) ;
Eker, Omer (Hospices Civils de Lyon) ;
Chalumeau, Vanessa (Hôpital Bicetre) ;
Kleinig, Timothy J. (Royal Adelaide Hospital) ;
Pop, Raoul (Hôpitaux Universitaires de Strasbourg) ;
Liu, Jianmin (Changhai Hospital) ;
Winters, Hugh S. (Royal Prince Alfred Hospital) ;
Shang, Xianjin (Yijishan Hospital of Wannan Medical College) ;
Rodriguez Vasquez, Alejandro (Hospital Clínic i Provincial de Barcelona) ;
Blasco, Jordi (Hospital Clínic i Provincial de Barcelona) ;
Arenillas, Juan F (Hospital Clínico Universitario de Valladolid) ;
Martinez-Galdamez, Mario (Hospital Clínico Universitario de Valladolid) ;
Brehm, Alex (University Hospital Basel (Basilea, Suïssa)) ;
Psychogios, Marios-Nikos (University Hospital Basel (Basilea, Suïssa)) ;
Lylyk, Pedro (Clínica Sagrada Familia (Buenos Aires, Argentina)) ;
Haussen, Diogo C. (Emory University (Altanta, Georgia)) ;
Al-Bayati, Alhamza R. (Emory University (Altanta, Georgia)) ;
Mohammaden, Mahmoud H. (Emory University (Altanta, Georgia)) ;
Fonseca, Luísa (Centro Hospitalar Universitário de São João (Portugal)) ;
Luís Silva, M. (Centro Hospitalar Universitário de São João (portugal)) ;
Montalverne, Francisco (Hospital Geral de Fortaleza (Brasil)) ;
Renieri, Leonardo (Careggi University Hospital (Florència, Itàlia)) ;
Mangiafico, Salvatore (Careggi University Hospital (Florència, Itàlia)) ;
Fischer, Urs (University Hospital Bern (Bern, Suïssa)) ;
Gralla, Jan (University Hospital Bern (Bern, Suïssa)) ;
Frei, Donald (Swedish Medical Center (USA)) ;
Chugh, Chandril (MAX Superspecialty Hospital (India)) ;
Mehta, Brijesh P. (Memorial Neuroscience Institute (Florida, USA)) ;
Nagel, Simon (University Hospital Heidelberg (Heidelberg, Alemanya)) ;
Mohlenbruch, Markus (University Hospital Heidelberg (Heidelberg, Alemanya)) ;
Ortega-Gutierrez, Santiago (University of Iowa (Iowa, USA)) ;
Farooqui, Mudassir (University of Iowa (Iowa, USA)) ;
Hassan, Ameer E (Valley Baptist Medical Center (Texas, USA)) ;
Taylor, Allan (University of Cape Town (Cape Town, Sud Àfrica)) ;
Lapergue, Bertrand (Hôpital Foch (Foch , França)) ;
Consoli, Arturo (Hôpital Foch (Foch , França)) ;
Campbell, Bruce C.V. (Royal Melbourne Hospital (Melbourne, Austràlia)) ;
Sharma, Malveeka (University of Washington (Seattle, USA)) ;
Walker, Melanie (University of Washington (Seattle, USA)) ;
Van Horn, Noel (Universitätsklinikum Hamburg-Eppendorf (Hamburg-Eppendorf, Alemanya)) ;
Fiehler, Jens (Universitätsklinikum Hamburg-Eppendorf (Hamburg-Eppendorf, Alemanya)) ;
Nguyen, Huy Thang (People's 115 Hospital (Vietnam)) ;
Nguyen, Quoc T. (People's 115 Hospital (Vietnam)) ;
Watanabe, Daisuke (IMS Tokyo-Katsushika General Hospital (Tokio, Japó)) ;
Zhang, Hao ;
Le, Huynh V. ;
Nguyen, Viet Q. (Hue Central Hospital (Vietnam)) ;
Shah, Ruchir (Erlanger Medical Center (USA)) ;
Devlin, Thomas (Erlanger Medical Center (USA)) ;
Khandelwal, Priyank (Rutgers University (USA)) ;
Linfante, Italo (Miami Cardiac and Vascular Institute ( USA)) ;
Izzath, Wazim (Nottingham University Hospitals NHS Trust (Regne Unit)) ;
Lavados, Pablo M. (Clínica Alemana Universidad del Desarrollo) ;
Olavarría, Veronica V. (Clínica Alemana Universidad del Desarrollo) ;
Sampaio Silva, Gisele (Hospital Israelita Albert Einstein (Sao Paolo, Brasil)) ;
de Carvalho Sousa, Anna Verena (Hospital Israelita Albert Einstein (Sao Paolo, Brasil)) ;
Kirmani, Jawad (Hackensack Meridian Health (New Jersey, USA)) ;
Bendszus, Martin (University Hospital Heidelberg (Alemanya)) ;
Amano, Tatsuo (Kyorin University (Japó)) ;
Yamamoto, Ryoo (Yokohama Brain and Spine Center (Japó)) ;
Doijiri, Ryosuke (Iwate Prefectural Central Hospital (Japó)) ;
Tokuda, Naoki (Japanese Red Cross Kyoto Daiichi Hospital (Japó)) ;
Yamada, Takehiro (Kyoto Second Red Cross Hospital (Japó)) ;
Terasaki, Tadashi (Japanese Red Cross Kumamoto Hospital (Japó)) ;
Yazawa, Yukako (Kohnan Hospital (Japó)) ;
Morris, Jane G. (Maine Medical Center (USA)) ;
Griffin, Emma (Beaumont Hospital (Dublín, Irlanda)) ;
Thornton, John (Beaumont Hospital (Dublín, Irlanda)) ;
Lavoie, Pascale (Hopital Enfant Jesus (Quebec, Canadà)) ;
Matouk, Charles (Yale New Haven Hospital (USA)) ;
Hill, M. D (University of Calgary (Calgary, Canadà)) ;
Demchuk, Andrew M. (University of Calgary (Calgary, Canadà)) ;
Killer-Oberpfalzer, Monika (University Hospital Salzburg (Salzburg, Àustria)) ;
Nahab, Fadi (Emory University School of Medicine (USA)) ;
Altschul, Dorothea (Valley Hospital (New Jersey, USA)) ;
Ramos-Pachón, Anna (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Pérez de la Ossa, Natalia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Kikano, Raghid (Lau Medical Center (Beirut, Líban)) ;
Boisseau, William (CHU Montreal (Canadà)) ;
Walker, Gregory (University of Ottawa (Canadà)) ;
Cordina, Steve M. (University of South Alabama (USA)) ;
Puri, Ajit (University of Massachusetts Medical Center (USA)) ;
Luisa Kuhn, Anna (University of Massachusetts Medical Center (USA)) ;
Gandhi, Dheeraj (University of Maryland (USA)) ;
Ramakrishnan, Pankajavalli (Riverside Regional Medical Center (Virginia, USA)) ;
Novakovic-White, Roberta (UT Southwestern (Texas, USA)) ;
Chebl, Alex (Henry Ford Health System (Detroit, USA)) ;
Kargiotis, Odysseas (Metropolitan Hospital (Piraeus, Grecia)) ;
Czap, Alexandra L (UTHealth McGovern Medical School (Houston, USA)) ;
Zha, Alicia M (UTHealth McGovern Medical School (Houston, USA)) ;
Masoud, Hesham E. (SUNY Upstate Medical University Hospital (USA)) ;
Lopez, Carlos (SUNY Upstate Medical University Hospital (USA)) ;
Ozretic, David (University Hospital Centre Zagreb (Croàcia)) ;
Al-Mufti, Fawaz (Westchester Medical Center (USA)) ;
Zie, Wenjie (Xinqiao Hospital of the Army Medical University) ;
Duan, Zhenhui (Wuhan No.1 Hospital) ;
Yuan, Zhengzhou (Affiliated Hospital of Southwest Medical University) ;
Huang, Wenguo (Maoming Traditional Chinese Medicine Hospital) ;
Hao, Yonggang (Shaw Shaw Hospital) ;
Luo, Jun (Mianyang 404 Hospital) ;
Kalousek, Vladimir (University Clinical Hospital Center Sestre Milosrdnice (Croàcia)) ;
Bourcier, Romain (CHU Nantes (França)) ;
Guile, Romain (CHU Nantes (França)) ;
Hetts, Steven (University of California San Francisco (USA)) ;
Al-Jehani, Hosam M. (King Fahad Hospital of the University (Aràbia Saudi)) ;
AlHazzani, Adel (King Saud University) ;
Sadeghi-Hokmabadi, Elyar (Tabriz University) ;
Teleb, Mohamed (Banner Desert Medical Center (USA)) ;
Payne, Jeremy (Banner Desert Medical Center) ;
Lee, Jin Soo (Ajou University Hospital) ;
Hong, Ji Man (Ajou University Hospital) ;
Sohn, Sung-Il (Kyemyung University) ;
Hwang, Yang-Ha (Kyungpook National University Hospital) ;
Shin, Dong Hoon (Gachon University Gil Hospital) ;
Roh, Hong Gee (Konkuk University Hospital) ;
Edgell, Randy (St. Louis University) ;
Khatri, Rakesh (Texas Tech University) ;
Smith, Ainsley (Cooper University Hospital) ;
Malik, Amer (University of Miami) ;
Liebeskind, David (UCLA) ;
Herial, Nabeel (Thomas Jefferson University Hospital) ;
Jabbour, Pascal (Thomas Jefferson University Hospital) ;
Magalhaes, Pedro (Hospital Sao Jose) ;
Ozdemir, Atilla Ozcan (Eskisehir Osmangazi University) ;
Aykac, Ozlem (Eskisehir Osmangazi University) ;
Uwatoko, Takeshi (Saga-ken Medical Centre Koseikan) ;
Dembo, Tomohisa (Saitama Medical Center) ;
Shimizu, Hisao (Nara City Hospital) ;
Sugiura, Yuri (Toyonaka Municipal Hospital) ;
Miyashita, Fumio (Kagoshima City Hospital) ;
Fukuda, Hiroki (Japanese Red Cross Matsue Hospital) ;
Miyake, Kosuke (Shiroyama Hospital) ;
Shimbo, Junsuke (Niigata City General Hospital) ;
Sugimura, Yusuke (Sugimura Hospital) ;
Beer-Furlan, Andre (Rush University Medical Center) ;
Joshi, Krishna (Rush University Medical Center) ;
Catanese, Luciana (McMaster University (Canadà)) ;
Abud, Daniel Giansante (Ribeirão Preto Medical School) ;
Neto, Octavio Giansante (Ribeirão Preto Medical School) ;
Mehrpour, Masoud (Shahid Beheshti University) ;
Al Hashmi, Amal (Khoula Hospital) ;
Saqqur, Mahar (Hamad Medical Corporation) ;
Mostafa, Abdulrahman (Alexandria University Hospital) ;
Fifi, Johanna T. (Mount Sinai Health System) ;
Hussain, Syed (Cleveland Clinic Abu Dhabi) ;
John, Seby (Cleveland Clinic Abu Dhabi) ;
Gupta, Rishi (WellStar Health) ;
Sivan-Hoffmann, Rotem (Rambam Health Care) ;
Reznik, Anna (Rambam Health Care) ;
Sani, Achmad Fidaus (General Hospital Dr) ;
Geyik, Serdar (Istanbul Aydın University) ;
Akıl, Eşref (Istanbul Aydın University) ;
Churojana, Anchalee (Siriraj Hospital) ;
Ghoreishi, Abdoreza (Zanjan University) ;
Saadatnia, Mohammad (Isfahan University) ;
Sharifipour, Ehsan (Qom University) ;
Ma, Alice (Royal North Shore Hospital) ;
Faulder, Ken (Royal North Shore Hospital) ;
Wu, Teddy (Christchurch Hospital) ;
Leung, Lester (Tufts Medical Center) ;
Malek, Adel (Tufts Medical Center) ;
Voetsch, Barbara (Beth Israel Lahey Health) ;
Wakhloo, Ajay (Beth Israel Lahey Health) ;
Rivera, Rodrigo (Instituto de Neurocirugia Dr. Asengo) ;
Barrientos Iman, Danny Moises (National Institute of Neurological Sciences of Lima) ;
Pikula, Aleksandra (University of Toronto (Canadà)) ;
Lioutas, Vasileios-Arsenios (Beth Israel Lahey Health) ;
Thomalla, Gotz (Universitätsklinikum Hamburg-Eppendorf) ;
Birnbaum, Lee (University of Texas San Antonio) ;
Machi, Paolo (Geneva University Hospitals (Suïssa)) ;
Bernava, Gianmarco (Geneva University Hospitals (Suïssa)) ;
McDermott, Mollie (University of Michigan) ;
Kleindorfer, Dawn (University of Michigan) ;
Wong, Ken (Royal London Hospital) ;
Patterson, Mary S. (Bon Secours Mercy Health) ;
Fiorot, Jose Antonio (Hospital-Estadual Central (Brasil)) ;
Huded, Vikram (NH Mazumdar Shaw Medical Center) ;
Mack, William (University of Southern California) ;
Tenser, Matthew (University of Southern California) ;
Eskey, Clifford (Dartmouth Hitchcock Medical Center) ;
Multani, Sumeet (Bayhealth Medical Center) ;
Kelly, Michael (University of Saskatchewan) ;
Janardhan, Vallabh (Medical City Plano Texas) ;
Cornett, Oriana (St. Joseph's University Medical Center) ;
Singh, Varsha (St. Joseph's University Medical Center) ;
Murayama, Yuichi (Jikei University School of Medicine) ;
Mokin, Maxim (University of South Florida) ;
Yang, Pengfei (Changhai Hospital) ;
Zhang, Xiaoxi (Changhai Hospital) ;
Yin, Congguo (Affiliated Hangzhou First People's Hospital) ;
Han, Hongxing (Linyi City People Hospital) ;
Peng, Ya (First People's Hospital) ;
Chen, Wenhuo (Zhangzhou Municipal Hospital) ;
Crosa, Roberto (Centro Endovascular Neurológico Médica) ;
Frudit, Michel E. (Universidade Federal de Sao Paulo) ;
Pandian, Jeyaraj D. (Christian Medical College) ;
Kulkarni, Anirudh (Christian Medical College) ;
Yagita, Yoshiki (Kawasaki Medical School) ;
Takenobu, Yohei (Osaka Red Cross Hospital) ;
Matsumaru, Yuji (University of Tsukuba) ;
Yamada, Satoshi (Saiseikai Central Hospital) ;
Kono, Ryuhei (Kinikyochuo Hospital) ;
Kanamaru, Takuya (NTT Medical Center) ;
Yamazaki, Hidekazu (UT Southwestern) ;
Sakaguchi, Manabu (Osaka General Medical Center) ;
Todo, Kenichi (Osaka University Graduate School of Medicine) ;
Yamamoto, Nobuaki (Tokushima University Graduate School of Biomedical Sciences) ;
Sonoda, Kazutaka (Saiseikai Fukuoka General Hospital) ;
Yoshida, Tomoko (Tane General Hospital) ;
Hashimoto, Hiroyuki (Osaka Rosai Hospital) ;
Nakahara, Ichiro (Fujita Health University School of Medicine) ;
Cora, Elena (Dalhousie University (Canadà)) ;
Volders, David (Dalhousie University (Canadà)) ;
Ducroux, Celina (CHU Montreal) ;
Shoamanesh, Ashkan (McMaster University (Canadà)) ;
Ospel, Johanna (University of Calgary) ;
Kaliaev, Artem (Boston Medical Center) ;
Ahmed, Saima (Lahore General Hospital) ;
Rashid, Umair (Lahore General Hospital) ;
Rebello, Leticia C. (Hospital Brasilia) ;
Pereira, Vitor Mendes (University of Toronto) ;
Fahed, Robert (University of Ottawa) ;
Chen, Michael (Rush University Medical Center) ;
Sheth, Sunil A. (UTHealth McGovern Medical School) ;
Palaiodimou, Lina (National Kapodistrian University of Athens) ;
Tsivgoulis, Georgios (National Kapodistrian University of Athens) ;
Chandra, Ronil (Monash Medical Center) ;
Koyfman, Feliks (New York-Presbyterian Queens) ;
Leung, Thomas (Prince of Wales Hospital (Australia)) ;
Khosravani, Houman (Sunnybrook Health Sciences Centre) ;
Dharmadhikari, Sushrut (Baptist Health) ;
Frisullo, Giovanni (Fondazione Policlinico Universitario A.Gemelli) ;
Calabresi, Paolo (Fondazione Policlinico Universitario A.Gemelli) ;
Tsiskaridze, Alexander (Ivane Javakhishvili Tbilisi State University) ;
Lobjanidze, Nino (Ivane Javakhishvili Tbilisi State University) ;
Grigoryan, Mikayel (Adventist Health Glendale) ;
Czlonkowska, Anna (Institute Psychiatry and Neurology) ;
de Sousa, Diana A. (Hospital de Santa Maria) ;
Demeestere, Jelle (Leuven University Hospital) ;
Liang, Conrad (Neurointerventional Radiology) ;
Sangha, Navdeep (Kaiser Permanente (California, USA)) ;
Lutsep, Helmi L. (Oregon University (USA)) ;
Ayo-Martín, Óscar (Complejo Hospitalario Universitario de Albacete) ;
Cruz-Culebras, Antonio (Hospital Universitario Ramón y Cajal (Madrid)) ;
Tran, Anh D. (Hue Central Hospital (Vietnam)) ;
Young, Chang Y. (Asan Medical Center) ;
Cordonnier, Charlotte (CHU de Lille) ;
Caparros, Francois (CHU de Lille) ;
De Lecinana, Maria Alonso (Hospital Universitario La Paz (Madrid)) ;
Fuentes, Blanca (Hospital Universitario La Paz (Madrid)) ;
Yavagal, Dileep (University of Miami) ;
Jovin, Tudor (Cooper University Hospital) ;
Spelle, Laurent (Hôpital Bicetre) ;
Moret, Jacques (Hôpital Bicetre) ;
Khatri, Pooja (University of Cincinnati) ;
Zaidat, Osama (Bon Secours Mercy Health) ;
Raymond, Jean (CHU Montreal (Canadà)) ;
Martins, Sheila (Hospital de Clínicas de Porto Alegre (Brasil)) ;
Nguyen, Thanh N (Boston Medical Center) ;
Universitat Autònoma de Barcelona
Background: The COVID-19 pandemic led to profound changes in the organization of health care systems worldwide. Aims: We sought to measure the global impact of the COVID-19 pandemic on the volumes for mechanical thrombectomy, stroke, and intracranial hemorrhage hospitalizations over a three-month period at the height of the pandemic (1 March-31 May 2020) compared with two control three-month periods (immediately preceding and one year prior). [...]
2021 - 10.1177/1747493021991652
International Journal of Stroke, Vol. 16 Núm. 5 (july 2021) , p. 573-584
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9.
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17 p, 2.6 MB |
DNA methylation analyses identify an intronic ZDHHC6 locus associated with time to recurrent stroke in the Vitamin Intervention for Stroke Prevention (VISP) clinical trial
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Davis Armstrong, N.M. (East Carolina University. Department of Biology) ;
Chen, Wei-Min (University of Virginia. Department of Public Health Sciences) ;
Hsu, F.C. (Wake Forest School of Medicine) ;
Brewer, M.S. (East Carolina University. Department of Biology) ;
Cullell, Natalia (Fundació per la Recerca Biomèdica i Social Mútua de Terrassa) ;
Fernandez-Cadenas, Israel (Institut d'Investigació Biomèdica Sant Pau) ;
Williams, S.R. (University of Virginia. Department of Neurology) ;
Sale, M.M. (University of Virginia. Department of Public Health Sciences) ;
Worrall, B.B. (University of Virginia. Department of Neurology) ;
Keene, K.L. (East Carolina University. Brody School of Medicine)
Aberrant DNA methylation profiles have been implicated in numerous cardiovascular diseases; however, few studies have investigated how these epigenetic modifications contribute to stroke recurrence. The aim of this study was to identify methylation loci associated with the time to recurrent cerebro- and cardiovascular events in individuals of European and African descent. [...]
2021 - 10.1371/journal.pone.0254562
PloS one, Vol. 16 Núm. 7 July (july 2021) , p. e0254562
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10.
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132 p, 6.7 MB |
Characterization of the movement of a circadian protein in the temperature-dependent root synchronization of Arabidopsis thaliana
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Chen, Weiwei ;
Más Martínez, Paloma, dir. ;
Tolrà Rovira, Roser, dir.
El rellotge circadià està sincronitzat per senyals mediambientals externes, principalment la llum i la temperatura. Entendre com respon el rellotge circadià de la planta a les oscil·lacions de temperatura és crucial per comprendre la capacitat de resposta de la planta a l'entorn. [...]
El reloj circadiano está sincronizado por señales medioambientales externas, principalmente la luz y la temperatura. Entender cómo responde el reloj circadiano de la planta a las oscilaciones de temperatura es crucial para comprender la capacidad de respuesta de la planta al medio ambiente. [...]
The circadian clock is synchronized by external environment cues, mostly through light and temperature. Explaining how the plant circadian clock responds to temperature oscillations is crucial to understanding plant responsiveness to the environment. [...]
2020
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