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13 p, 786.1 KB A randomized placebo-controlled phase II study of a Pseudomonas vaccine in ventilated ICU patients / Rello, Jordi (Hospital Universitari Vall d'Hebron) ; Krenn, Claus-Georg (Medical University of Vienna) ; Locker, Gottfried (Medical University of Vienna) ; Pilger, Ernst (University Hospital Graz, Graz, Austria) ; Madl, Christian (Medical University of Vienna) ; Balica, Laura (Emergency Clinical Hospital Bucharest) ; Dugernier, Thierry (Clinique St. Pierre, Ottignies, Belgium) ; Laterre, Pierre-Francois (St. Luc University Hospital UCL, Université Catholique de Louvain, Brussels, Belgium) ; Spapen, Herbert (University Hospital Vrije Universiteit Brussels, Brussels, Belgium) ; Depuydt, Pieter (UZ Gent, Gent, Belgium) ; Vincent, Jean-Louis (Erasme University Hospital, Université Libre de Bruxelles, Brussels, Belgium) ; Bogár, Lajos (University of Pécs, Pécs, Hungary) ; Szabó, Zsuzsanna (Uzsoki Hospital, Budapest, Hungary) ; Völgyes, Barbara (Bajcsy Zsilinszky Hospital and Polyclinic, Budapest, Hungary) ; Máñez, Rafael (Hospital Universitari Bellvitge) ; Cakar, Nahit (Istanbul University Capa Medical Faculty, Istanbul, Turkey) ; Ramazanoglu, Atilla (Akdeniz University, Antalya, Turkey) ; Topeli, Arzu (Hacettepe University Hospital, Ankara, Turkey) ; Mastruzzo, Maria A. (Hospital Dr. Carlos Bocalandro, Buenos Aires, Argentina) ; Jasovich, Abel (Sanatorio Güemes, Buenos Aires, Argentina) ; Remolif, Christian G. (Hospital "Heroes de Malvinas", Buenos Aires, Argentina) ; del Carmen Soria, Liliana (Hospital Central Mendoza, Ciudad de Mendoza, Argentina) ; Andresen Hernandez, Max A. (Hospital Clinico, Santiago, Chile) ; Ruiz Balart, Carolina (Hospital Dr. Sótero del Rio, Santiago, Chile) ; Krémer, Ildikó (Flor Ferenc County Hospital, Kistarcsa, Hungary) ; Molnár, Zsolt (University of Szeged, Szeged, Hungary) ; von Sonnenburg, Frank (University of Munich, Germany) ; Lyons, Arthur (Walter Reed Army Institute of Research, Robert Grant Avenue, Silver Spring, MD 20910 USA) ; Joannidis, Michael (Medical University of Innsbruck, Innsbruck, Austria) ; Burgmann, Heinz (Medical University of Vienna) ; Welte, Tobias (Hannover Medical School, Hannover, Germany) ; Klingler, Anton (Assign Data Management and Biostatistics GmbH, Innsbruck, Austria) ; Hochreiter, Romana (Valneva Austria GmbH, Campus Vienna Biocenter 3, Vienna, Austria) ; Westritschnig, Kerstin (Valneva Austria GmbH, Campus Vienna Biocenter 3, Vienna, Austria) ; Universitat Autònoma de Barcelona
Currently, no vaccine against Pseudomonas is available. IC43 is a new, recombinant, protein (OprF/I)-based vaccine against the opportunistic pathogen, Pseudomonas aeruginosa, a major cause of serious hospital-acquired infections. [...]
2017 - 10.1186/s13054-017-1601-9
Critical Care, Vol. 21 (february 2017)  

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