Dipòsit Digital de Documents de la UAB 3 registres trobats  La cerca s'ha fet en 0.00 segons. 
1.
12 p, 2.5 MB Structural basis for the SUMO protease activity of the atypical ubiquitin-specific protease USPL1 / Li, Ying (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Varejão, Nathalia (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Reverter i Cendrós, David (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí")
Post-translational protein modifications by ubiquitin and ubiquitin-like modifiers regulate many major pathways in the cell. These modifications can be reversed by de-ubiquitinating enzymes such as ubiquitin-specific proteases (USPs). [...]
2022 - 10.1038/s41467-022-29485-0
Nature communications, Vol. 13 (April 2022) , art. 1819  
2.
24 p, 7.8 MB Molecular Mechanisms of DUBs Regulation in Signaling and Disease / Li, Ying (Universitat Autònoma de Barcelona. Departament de Bioquímica i de Biologia Molecular) ; Reverter i Cendrós, David (Universitat Autònoma de Barcelona. Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí")
The large family of deubiquitinating enzymes (DUBs) are involved in the regulation of a plethora of processes carried out inside the cell by protein ubiquitination. Ubiquitination is a basic pathway responsible for the correct protein homeostasis in the cell, which could regulate the fate of proteins through the ubiquitin-proteasome system (UPS). [...]
2021 - 10.3390/ijms22030986
International journal of molecular sciences, Vol. 22, Issue 3 (February 2021) , art. 986  
3.
35 p, 2.1 MB Modeling Fanconi anemia pathogenesis and therapeutics using integration-free patient iPSCs / Liu, Guang-Hui (Salk Institute for Biological Studies (La Jolla, Estats Units d'Amèrica). Laboratory of Gene Expression) ; Suzuki (Salk Institute for Biological Studies (La Jolla, Estats Units d'Amèrica). Laboratory of Gene Expression) ; Li, Mo (Salk Institute for Biological Studies (La Jolla, Estats Units d'Amèrica). Laboratory of Gene Expression) ; Qu, Jing (Salk Institute for Biological Studies (La Jolla, Estats Units d'Amèrica). Laboratory of Gene Expression) ; Montserrat, Núria (Centro de Medicina Regenerativa de Barcelona) ; Tarantino, Carolina (Centro de Medicina Regenerativa de Barcelona) ; Gu, Ying (Salk Institute for Biological Studies (La Jolla, Estats Units d'Amèrica). Laboratory of Gene Expression) ; Yi, Fei (Salk Institute for Biological Studies (La Jolla, Estats Units d'Amèrica). Laboratory of Gene Expression) ; Xu, Xiuling (Zhongguo ke xue yuan. National Laboratory of Biomacromolecules) ; Zhang, Weiqi (Zhongguo ke xue yuan. National Laboratory of Biomacromolecules) ; Ruiz, Sergio (Salk Institute for Biological Studies (La Jolla, Estats Units d'Amèrica). Laboratory of Gene Expression) ; Plongthongkum, Nongluk (University of California. Department of Bioengineering) ; Zhang, Kun (University of California. Department of Bioengineering) ; Masuda, Shigeo (Salk Institute for Biological Studies (La Jolla, Estats Units d'Amèrica). Laboratory of Gene Expression) ; Nivet, Emmanuel (Salk Institute for Biological Studies (La Jolla, Estats Units d'Amèrica). Laboratory of Gene Expression) ; Tsunokawa, Yuji (Salk Institute for Biological Studies (La Jolla, Estats Units d'Amèrica). Laboratory of Gene Expression) ; Soligalla, Rupa Devi (Salk Institute for Biological Studies (La Jolla, Estats Units d'Amèrica). Laboratory of Gene Expression) ; Goebl, April (Salk Institute for Biological Studies (La Jolla, Estats Units d'Amèrica). Laboratory of Gene Expression) ; Aizawa, Emi (Salk Institute for Biological Studies (La Jolla, Estats Units d'Amèrica). Laboratory of Gene Expression) ; Kim, Na Young (Salk Institute for Biological Studies (La Jolla, Estats Units d'Amèrica). Laboratory of Gene Expression) ; Kim, Jessica (Salk Institute for Biological Studies (La Jolla, Estats Units d'Amèrica). Laboratory of Gene Expression) ; Dubova, Ilir (Salk Institute for Biological Studies (La Jolla, Estats Units d'Amèrica). Laboratory of Gene Expression) ; Li, Ying (Zhongguo ke xue yuan. National Laboratory of Biomacromolecules) ; Ren, Ruotong (Zhongguo ke xue yuan. National Laboratory of Biomacromolecules) ; Benner, Chris (Integrative Genomics and Bioinformatics Core. Salk Institute for Biological Studies) ; Sol, Antonio del (Luxembourg Centre for Systems Biomedicine) ; Bueren, Juan (Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz) ; Trujillo Quintero, Juan Pablo (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Surrallés i Calonge, Jordi (Universitat Autònoma de Barcelona. Departament de Genètica i de Microbiologia) ; Cappelli, Enrico (Istituto "Giannina Gaslini" di Genova) ; Dufour, Carlo (Istituto "Giannina Gaslini" di Genova) ; Rodriguez Esteban, Concepción (Salk Institute for Biological Studies (La Jolla, Estats Units d'Amèrica). Laboratory of Gene Expression) ; Izpisua Belmonte, Juan Carlos (Salk Institute for Biological Studies (La Jolla, Estats Units d'Amèrica). Laboratory of Gene Expression)
Fanconi anaemia (FA) is a recessive disorder characterized by genomic instability, congenital abnormalities, cancer predisposition and bone marrow (BM) failure. However, the pathogenesis of FA is not fully understood partly due to the limitations of current disease models. [...]
Altres ajuts: Strategic Priority Research Program of the Chinese Academy of Sciences (XDA01020312), National Basic Research Program of China (973 Program,2014CB964600;2014CB910500), NSFC (81271266, 31222039, 81330008, 31201111, 81371342, 81300261, 81300677), Key Research Program of the Chinese Academy of Sciences (KJZD-EW-TZ-L05), Beijing Natural Science Foundation (7141005; 5142016), the Thousand Young Talents program of China, National Laboratory of Biomacromolecules (012kf02, 2013kf05;2013kf11;2014kf02), and State Key Laboratory of Drug Research (SIMM1302KF-17). [...]

2014 - 10.1038/ncomms5330
Nature communications, Vol. 5, article 4330 (July 2014)  

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