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1.
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HLA-DR Expression on Monocytes and Sepsis Index Are Useful in Predicting Sepsis
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Quirant-Sánchez, Bibiana (Universitat Autònoma de Barcelona. Departament de Biologia Celular, de Fisiologia i d'Immunologia) ;
Plans Galván, Oriol (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Lucas, Ester (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Argudo, Eduard (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Martínez Cáceres, Eva Maria (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Arméstar, Fernando (Universitat Autònoma de Barcelona. Departament de Medicina)
2023 -  10.3390/biomedicines11071836
Biomedicines, Vol. 11, Num. 7, 2023. art. 1836
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2.
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9 p, 1.3 MB |
Restrictive diets are unnecessary for colonoscopy : Non-inferiority randomized trial
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Machlab, Salvador (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Martínez-Bauer, Eva (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
López López, Pilar (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Ruiz-Ramirez, Pablo (Hospital Universitari MútuaTerrassa) ;
Gómez, Bárbara (Hospital de Mataró. Consorci Sanitari del Maresme) ;
Gimeno-Garcia, Antonio Z. (Hospital Universitario de Canarias (La Laguna)) ;
Pujals, María del Mar (Hospital Universitari MútuaTerrassa) ;
Tanco, Sara (Hospital de Mataró. Consorci Sanitari del Maresme) ;
Sargatal, Lluïsa (Consorci Sanitari de Terrassa) ;
Pérez, Betty (Hospital Universitario de Canarias (La Laguna)) ;
Justicia, Reyes (Consorci Sanitari de Terrassa) ;
Enguita, Mónica (Navarrabiomed) ;
Piqué, Núria (Universitat de Barcelona Facultat de Farmàcia i Ciències de l'Alimentació) ;
Valero, Oliver (Universitat Autònoma de Barcelona. Departament de Matemàtiques) ;
Calvet Calvo, Xavier (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Campo Fernández de los Rios, Rafael (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT))
Background and study aims In colonoscopy, preparation is often regarded as the most burdensome part of the intervention. Traditionally, specific diets have been recommended, but the evidence to support this policy is insufficient. [...]
2024 - 10.1055/a-2256-5356
Endoscopy International Open, Vol. 12 (march 2024) , p. E352-E360
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3.
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9 p, 526.0 KB |
Burden of refractory and unexplained chronic cough on patients' lives : a cohort study
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Puente, Luis (Hospital Universitario Gregorio Marañón) ;
Dávila, Ignacio (Hospital Clínico Universitario (Salamanca)) ;
Quirce Gancedo, Santiago (Hospital Universitario La Paz (Madrid)) ;
Crespo Lessmann, Astrid (Hospital de la Santa Creu i Sant Pau (Barcelona, Catalunya)) ;
Martínez-Moragón, Eva (Hospital Universitari Doctor Peset (València)) ;
Sola, Javier (Hospital Universitario Ramón y Cajal (Madrid)) ;
Nieto, María Luisa (Hospital Arnau de Vilanova (València)) ;
González-Barcala, Francisco-Javier (Universidad de Santiago de Compostela) ;
Cea-Calvo, Luis (Medical Affairs) ;
Sánchez-Jareño, Marta (Medical Affairs) ;
Rivas-Pardinas, Cristina (Medical Affairs) ;
Domingo, Christian (Parc Taulí Hospital Universitari. Institut d'Investigació i Innovació Parc Taulí (I3PT)) ;
Universitat Autònoma de Barcelona
Chronic cough (cough lasting for ≥8 weeks) can lead to significant impairment in quality of life (QoL). Using patient-reported outcomes, this cohort study assessed the perceived impact of chronic cough on QoL and everyday life in patients from outpatient hospital clinics with refractory chronic cough (RCC) or unexplained chronic cough (UCC). [...]
2023 - 10.1183/23120541.00425-2023
ERJ Open Research, Vol. 9 (september 2023)
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4.
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16 p, 1.1 MB |
Characterization and Factors Associated with Poor Asthma Control in Adults with Severe Eosinophilic Asthma
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Padró-Casas, Clara (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Basagaña, Maria (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Rivera-Ortún, María Luisa (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
García-Olivé, Ignasi (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Pollan-Guisasola, Carlos (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Teniente-Serra, Aina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Martínez-Cáceres, Eva (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Navarro, José Tomás (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Abad Capa, Jorge (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Rosell, Antoni (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Roger, Albert (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Martínez-Rivera, Carlos (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Universitat Autònoma de Barcelona.
Departament de Medicina
A study was conducted in 98 adult patients diagnosed with severe eosinophilic asthma (73. 5% women, mean age 47. 2 years) and followed prospectively for 1 year. The aim of the study was to characterize this population and to identify factors associated with poor prognosis at 1 year of follow-up. [...]
2023 - 10.3390/jpm13071173
Journal of personalized medicine, Vol. 13 Núm. 7 (july 2023)
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5.
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18 p, 3.4 MB |
Single-cell multi-omics analysis of COVID-19 patients with pre-existing autoimmune diseases shows aberrant immune responses to infection
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Barmada, Anis (Department of Medical Genetics. University of Cambridge) ;
Handfield, Louis-François (Wellcome Sanger Institute (Regne Unit)) ;
Godoy-Tena, Gerard (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
de la Calle-Fabregat, Carlos (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Ciudad, Laura (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Arutyunyan, Anna (Wellcome Sanger Institute (Regne Unit)) ;
Andrés-León, Eduardo (Instituto de Parasitología y Biomedicina "López-Neyra") ;
Hoo, Regina (Wellcome Sanger Institute (Regne Unit)) ;
Porter, Tarryn (Wellcome Sanger Institute (Regne Unit)) ;
Oszlanczi, Agnes (Wellcome Sanger Institute (Regne Unit)) ;
Richardson, Laura (Wellcome Sanger Institute (Regne Unit)) ;
Calero-Nieto, Fernando (Department of Haematology and Wellcome & MRC Cambridge Stem Cell Institute. University of Cambridge) ;
Wilson, Nicola K. (Department of Haematology and Wellcome & MRC Cambridge Stem Cell Institute. University of Cambridge) ;
Marchese, Domenica (Centre de Regulació Genòmica) ;
Sancho-Serra, Carmen (Wellcome Sanger Institute. Wellcome Genome Campus) ;
Carrillo, Jorge (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Presas-Rodríguez, Silvia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Ramo-Tello, Cristina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Ruiz-Sanmartin, Adolfo (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Ferrer, Ricard (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Ruiz-Rodriguez, Juan Carlos (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Martínez Gallo, Mónica (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Munera-Campos, Mónica (Institut Germans Trias i Pujol) ;
Carrascosa, José Manuel (Institut Germans Trias i Pujol) ;
Göttgens, Berthold (Department of Haematology and Wellcome & MRC Cambridge Stem Cell Institute. University of Cambridge) ;
Heyn, Holger (Universitat Pompeu Fabra) ;
Prigmore, Elena (Wellcome Sanger Institute (Regne Unit)) ;
Casafont-Solé, Ivette (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Solanich, Xavier (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Sánchez-Cerrillo, Idelfonso (Department of Immunology. Hospital Universitario La Princesa) ;
González-Álvaro, Isidoro (Rheumatology Service. Hospital Universitario La Princesa) ;
Raimondo, Maria Gabriella (Deutsches Zentrum Immuntherapie. Friedrich-Alexander-University Erlangen-Nürnberg and Universitätsklinikum Erlangen) ;
Ramming, Andreas (Deutsches Zentrum Immuntherapie. Friedrich-Alexander-University Erlangen-Nürnberg and Universitätsklinikum Erlangen) ;
Martin, Javier (Instituto de Parasitología y Biomedicina "López-Neyra") ;
Martínez Cáceres, Eva María (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Ballestar, Esteban (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras) ;
Vento-Tormo1, Roser (Wellcome Sanger Institute. Wellcome Genome Campus) ;
Rodríguez-Ubreva, Javier (Institut Germans Trias i Pujol. Institut de Recerca contra la Leucèmia Josep Carreras)
In COVID-19, hyperinflammatory and dysregulated immune responses contribute to severity. Patients with pre-existing autoimmune conditions can therefore be at increased risk of severe COVID-19 and/or associated sequelae, yet SARS-CoV-2 infection in this group has been little studied. [...]
2024 - 10.1002/eji.202350633
European Journal of Immunology, Vol. 54 Núm. 1 (january 2024) , p. 2350633
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6.
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7.
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10 p, 1.8 MB |
A proposed approach to chronic airway disease (CAD) using therapeutic goals and treatable traits : A look to the future
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Pérez de Llano, Luis (University Hospital Lucus Augusti (Lugo, Galícia)) ;
Miravitlles, Marc (Hospital Universitari Vall d'Hebron. Institut de Recerca) ;
Golpe, Rafael (University Hospital Lucus Augusti (Lugo, Galícia)) ;
Alvarez Gutiérrez, Francisco Javier (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
Cisneros, Carolina (Hospital Universitario La Princesa (Madrid)) ;
Almonacid, Carlos (Hospital Universitario Ramón y Cajal (Madrid)) ;
Martínez-Moragón, Eva (Hospital Universitari Doctor Peset (València)) ;
González-Barcala, Francisco-Javier (Universidade de Santiago de Compostela) ;
Ramos-Barbón, David (Institut d'Investigació Biomèdica Sant Pau) ;
Plaza, Vicente (Institut d'Investigació Biomèdica Sant Pau) ;
López-Campos, José Luis (Hospital Universitario Virgen del Rocío (Sevilla, Andalusia)) ;
De Torres, Juan Pablo (Queen's University) ;
Casanova Macario, Ciro (Hospital Universitario Nuestra Señora de Candelaria (Santa Cruz de Tenerife)) ;
García-Rivero, J. L. (Hospital de Laredo) ;
Rodriguez Hermosa, Juan Luis (Hospital Clínico San Carlos (Madrid)) ;
Calle Rubio, Myriam (Hospital Clínico San Carlos (Madrid)) ;
Soler-Cataluña, Juan José (Hospital Arnau de Vilanova (València)) ;
Cosio, Borja G (Clínica Quirón-Rotger) ;
Universitat Autònoma de Barcelona
Chronic airflow obstruction affects a wide range of airway diseases, the most frequent of which are asthma, COPD, and bronchiectasis; they are clearly identifiable in their extremes, but quite frequently overlap in some of their pathophysiological and clinical characteristics. [...]
2020 - 10.2147/COPD.S263430
International journal of COPD, Vol. 15 (2020) , p. 2091-2100
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8.
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9 p, 1.0 MB |
Cytotoxic NK cells phenotype and activated lymphocytes are the main characteristics of patients with alcohol-associated liver disease
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Zurera Egea, Coral (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Teniente Serra, Aina (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ;
Fuster, Daniel (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Martínez Cáceres, Eva María (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Muga, Roberto (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Zuluaga Blanco, Yenny Paola (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Universitat Autònoma de Barcelona
T cells, natural killer (NK) and NKT cells have opposing actions in the development of alcohol-associated liver fibrosis. We aimed to evaluate the phenotype of NK cells, NKT cells and activated T cells in patients with alcohol use disorder (AUD) according to the presence of advanced liver fibrosis (ALF). [...]
2023 - 10.1007/s10238-023-01121-1
Clinical and Experimental Medicine, Vol. 23, Num. 7 (november 2023) , p. 3539-3547
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9.
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19 p, 7.5 MB |
Assessing Blood-Based Biomarkers to Define a Therapeutic Window for Natalizumab
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Granell-Geli, Júlia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Izquierdo-Gracia, Cristina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Sellés-Rius, Ares (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Teniente Serra, Aina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Presas-Rodríguez, Silvia (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Mansilla Lopez, Maria Jose (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Brieva Ruiz, Luis (Hospital Universitari Arnau de Vilanova) ;
Sotoca Fernández, Javier (Hospital Universitari MútuaTerrassa (Terrassa, Catalunya)) ;
Mañé-Martínez, María Alba (Hospital Universitari Joan XXIII de Tarragona) ;
Moral, Ester (Hospital de Sant Joan Despí Moisès Broggi) ;
Bragado, Irene (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Goelz, Susan (Biogen Idec) ;
Martínez Cáceres, Eva María (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Ramo-Tello, Cristina (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Universitat Autònoma de Barcelona
Natalizumab is a monoclonal antibody that binds CD49d. Although it is one of the most effective treatments for Relapsing-Remitting Multiple Sclerosis (RRMS), a dosing regimen has not been optimized for safety and efficacy in individual patients. [...]
2021 - 10.3390/jpm11121347
Journal of personalized medicine, Vol. 11 (december 2021)
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10.
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12 p, 3.7 MB |
Skewed Cellular Distribution and Low Activation of Functional T-Cell Responses in SARS-CoV-2 Non-Seroconvertors
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Kilpeläinen, Athina (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Jiménez-Moyano, Esther (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Blanch-Lombarte, Oscar (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Ouchi, Dan (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Peña, Ruth (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Quirant, Bibiana (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Pérez-Caballero, Raúl (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Chamorro, Anna (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Blanco Guillermo, Ignacio (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Martínez Cáceres, Eva María (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Paredes, Roger (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Mateu, Lourdes (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ;
Carrillo, Jorge (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Blanco, Julià (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Brander, Christian (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Massanella, Marta (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Clotet Sala, Bonaventura (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Prado, Julia G. (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ;
Universitat Autònoma de Barcelona
The role of T cells in the control of SARS-CoV-2 infection has been underestimated in favor of neutralizing antibodies. However, cellular immunity is essential for long-term viral control and protection from disease severity. [...]
2022 - 10.3389/fimmu.2022.815041
Frontiers in immunology, Vol. 13 (may 2022)
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