Dipòsit Digital de Documents de la UAB 30 registres trobats  anterior11 - 20següent  anar al registre: La cerca s'ha fet en 0.01 segons. 
11.
30 p, 2.6 MB Divergent paths for the selection of immunodominant epitopes from distinct antigenic sources / Kim, AeRyon (The Johns Hopkins University. School of Medicine) ; Hartman, Isamu Z. (The Johns Hopkins University. School of Medicine) ; Poore, Brad (Johns Hopkins University. School of Medicine) ; Boronina, Tatiana (The Johns Hopkins University. School of Medicine) ; Cole, Robert N. (The Johns Hopkins University. School of Medicine) ; Song, Nianbin (The Johns Hopkins University. School of Medicine) ; Ciudad, M. Teresa (Institut de Biotecnologia i de Biomedicina "Vicent Villar Palasí") ; Caspi, Rachel R. (National Eye Institute) ; Jaraquemada, Dolores (Universitat Autònoma de Barcelona. Departament de Biologia Cel·lular, de Fisiologia i d'Immunologia) ; Sadegh-Nasseri, Scheherazade (Johns Hopkins University. School of Medicine)
Immunodominant epitopes are few selected epitopes from complex antigens that initiate T cell responses. Here, to provide further insights into this process, we use a reductionist cell-free antigen processing system composed of defined components. [...]
2014 - 10.1038/ncomms6369
Nature communications, Vol. 5 (2014) , art. 5369  
12.
7 p, 1.3 MB Femtolitre chemistry assisted by microfluidic pen lithography / Carbonell Fernández, Carlos (Institut Catala de Nanociencia i Nanotecnologia) ; Stylianou, Kyriakos C. (Institut Catala de Nanociencia i Nanotecnologia) ; Hernando Campos, Jordi (Universitat Autònoma de Barcelona. Departament de Química) ; Evangelio Castells, María Emilia (Institut Catala de Nanociencia i Nanotecnologia) ; Barnett, Sarah A. (Harwell Science and Innovation Campus) ; Nettikadan, Saju (Illinois Science and Technology Park) ; Imaz, Inhar (Institut Catala de Nanociencia i Nanotecnologia) ; Maspoch Comamala, Daniel (Institut Catala de Nanociencia i Nanotecnologia)
Chemical reactions at ultrasmall volumes are becoming increasingly necessary to study biological processes, to synthesize homogenous nanostructures and to perform high-throughput assays and combinatorial screening. [...]
2013 - 10.1038/ncomms3173
Nature communications, Vol. 4 (Jul. 2013) . art. 2173  
13.
8 p, 625.6 KB Responses of sequential and hierarchical phenological events to warming and cooling in alpine meadows / Li, Xine (Zhongguo ke xue yuan. Institute of Tibetan Plateau Research) ; Jiang, Lili (Zhongguo ke xue yuan. Institute of Tibetan Plateau Research) ; Meng, Fandong (Zhongguo ke xue yuan. Institute of Tibetan Plateau Research) ; Wang, Shiping (Zhongguo ke xue yuan. Institute of Tibetan Plateau Research) ; Niu, Haishan (Zhongguo ke xue yuan. Da xue) ; Iler, Amy M. (Aarhus universitet. Aarhus Institute of Advanced Studies) ; Duan, Jichuan (Tianjin da xue) ; Zhang, Zhenhua (Zhongguo ke xue yuan. Xi bei gao yuan sheng wu yan jiu suo) ; Luo, Caiyun (Zhongguo ke xue yuan. Xi bei gao yuan sheng wu yan jiu suo) ; Cui, Shujuan (Zhongguo ke xue yuan. Institute of Tibetan Plateau Research) ; Zhang, Lirong (Zhongguo ke xue yuan. Institute of Tibetan Plateau Research) ; Li, Yaoming (Zhongguo ke xue yuan. Institute of Tibetan Plateau Research) ; Wang, Qi (Zhongguo ke xue yuan. Institute of Tibetan Plateau Research) ; Zhou, Yang (Zhongguo ke xue yuan. Institute of Tibetan Plateau Research) ; Bao, Xiaoying (Zhongguo ke xue yuan. Da xue) ; Dorji, Tsechoe (Zhongguo ke xue yuan. Institute of Tibetan Plateau Research) ; Li, Yingnian (Zhongguo ke xue yuan. Xi bei gao yuan sheng wu yan jiu suo) ; Peñuelas, Josep (Centre de Recerca Ecològica i Aplicacions Forestals) ; Du, Mingyuan (Institute for Agro-Environmental Sciences (Tsukuba, Japan)) ; Zhao, Xinquan (Zhongguo ke xue yuan. Xi bei gao yuan sheng wu yan jiu suo) ; Zhao, Liang (Zhongguo ke xue yuan. Xi bei gao yuan sheng wu yan jiu suo) ; Wang, Guojie (Eastern Oregon Agricultural Research Center)
Organisms’ life cycles consist of hierarchical stages, from a single phenological stage (for example, flowering within a season), to vegetative and reproductive phases, to the total lifespan of the individual. [...]
2016 - 10.1038/ncomms12489
Nature communications, Vol. 7 (2016) , art. 12489  
14.
8 p, 752.8 KB Environmental variation and the evolution of large brains in birds / Sayol i Altarriba, Ferran (Centre de Recerca Ecològica i Aplicacions Forestals)) ; Maspons, Joan (Centre de Recerca Ecològica i Aplicacions Forestals) ; Lapiedra i González, Oriol (Harvard University. Department of Organismic and Evolutionary Biology) ; Iwaniuk, Andrew N. (University of Lethbridge. Department of Neuroscience) ; Székely, Tamás (University of Bath. Department of Biology and Biochemistry) ; Sol, Daniel (Centre de Recerca Ecològica i Aplicacions Forestals)
Environmental variability has long been postulated as a major selective force in the evolution of large brains. However, assembling evidence for this hypothesis has proved difficult. Here, by combining brain size information for over 1,200 bird species with remote-sensing analyses a to estimate temporal variation in ecosystem productivity, we show that larger brains (relative to body size) are more likely to occur in species exposed to larger environmental variation throughout their geographic range. [...]
2016 - 10.1038/ncomms13971
Nature communications, Vol. 7 (des. 2016) , art. 13971  
15.
6 p, 528.3 KB Generalized laws of thermodynamics in the presence of correlations / Bera, Manabendra N. (Universitat Politècnica de Catalunya. Institut de Ciències Fotòniques) ; Riera, Arnau (Universitat Politècnica de Catalunya. Institut de Ciències Fotòniques) ; Lewenstein, Maciej (Universitat Politècnica de Catalunya. Institut de Ciències Fotòniques) ; Winter, Andreas (Universitat Autònoma de Barcelona. Departament de Física)
The laws of thermodynamics, despite their wide range of applicability, are known to break down when systems are correlated with their environments. Here we generalize thermodynamics to physical scenarios which allow presence of correlations, including those where strong correlations are present. [...]
2017 - 10.1038/s41467-017-02370-x
Nature communications, Vol. 8 (2017) , art. 2180
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16.
13 p, 4.7 MB Uncertainty in soil data can outweigh climate impact signals in crop yield simulations / Folberth, Christian (International Institute for Applied Systems Analysis) ; Rastislav Skalsky (International Institute for Applied Systems Analysis) ; Moltchanova, Elena (International Institute for Applied Systems Analysis) ; Balkovic, Juraj (International Institute for Applied Systems Analysis) ; Azevedo, Ligia B. (International Institute for Applied Systems Analysis) ; Obersteiner, Michael (International Institute for Applied Systems Analysis) ; Van der Velde, Marijn (European Commission. Joint Research Centre)
Global gridded crop models (GGCMs) are increasingly used for agro-environmental assessments and estimates of climate change impacts on food production. Recently, the influence of climate data and weather variability on GGCM outcomes has come under detailed scrutiny, unlike the influence of soil data. [...]
2017 - 10.1038/ncomms1187
Nature communications, Vol. 7 (2016) , art. 11872  
17.
9 p, 1.2 MB Transcriptomic and macroevolutionary evidence for phenotypic uncoupling between frog life history phases / Wollenberg Valero, Katharina C. (Bethune-Cookman University. Department of Natural Sciences) ; Garcia-Porta, J. (Centre de Recerca Ecològica i Aplicacions Forestals) ; Rodríguez, Ariel (Technische Universität Braunschweig. Division of Evolutionary Biology) ; Arias, Mónica (Universität München. Division of Evolutionary Biology) ; Shaha, Abhijeet (Universität München. Division of Evolutionary Biology) ; Randrianiaina, Roger Daniel (Technische Universität Braunschweig. Division of Evolutionary Biology) ; Brown, L. Brown (Southern Illinois University) ; Glaw, Frank (Zoologische Staatssammlung München) ; Amat, Félix (Museu de Granollers. Àrea de Ciències Naturals) ; Künzel, Sven (Max Planck Institute for Developmental Biology) ; Metzler, Dirk (Universität München. Division of Evolutionary Biology) ; Isokpehi, Raphael D. (Bethune-Cookman University. Department of Natural Sciences) ; Vences, Miguel (Technische Universität Braunschweig. Division of Evolutionary Biology)
Anuran amphibians undergo major morphological transitions during development, but the contribution of their markedly different life-history phases to macroevolution has rarely been analysed. Here we generate testable predictions for coupling versus uncoupling of phenotypic evolution of tadpole and adult life-history phases, and for the underlying expression of genes related to morphological feature formation. [...]
2017 - 10.1038/ncomms15213
Nature communications, Vol. 8 (May 2017) , art. 15213  
18.
16 p, 3.8 MB Mutations in SLC39A14 disrupt manganese homeostasis and cause childhood-onset parkinsonism-dystonia / Tuschl, Karin (University College London. Institute of Child Health) ; Meyer, Esther (University College London. Institute of Child Health) ; Valdivia, Leonardo E. (University College London. Department of Cell and Developmental Biology) ; Zhao, Ningning (Oregon Health and Science University. Department of Cell, Development and Cancer Biology) ; Dadswell, Chris (University of Sussex. Department of Chemistry, School of Life Sciences) ; Abdul-Sada, Alaa (University of Sussex. Department of Chemistry, School of Life Sciences) ; Hung, Christina Y. (Harvard Medical School. Division of Genetics and Genomics) ; Simpson, Michael A. (King's College London School of Medicine. Division of Genetics and Molecular Medicine) ; Chong, W.K. (Great Ormond Street Hospital for Children. Department of Radiology (Londres)) ; Jacques, Thomas S. (Great Ormond Street Hospital for Children. Department of Histopathology (Londres)) ; Woltjer, Randy L. (Oregon Health and Science University. Department of Pathology) ; Eaton, Simon (University College London. Institute of Child Health) ; Gregory, Allison (Oregon Health and Science University. Department of Molecular and Medical Genetics) ; Sanford, Lynn (Oregon Health and Science University. Department of Molecular and Medical Genetics) ; Kara, Eleanna (University College London. Institute of Neurology) ; Houlden, Henry (University College London. Institute of Neurology) ; Cuno, Stephan M. (Technical University of Munich. Institute of Human Genetics) ; Prokisch, Holger (Technical University of Munich. Institute of Human Genetics) ; Valletta, Lorella (Oregon Health and Science University. Department of Molecular and Medical Genetics) ; Tiranti, Valeria (Oregon Health and Science University. Department of Molecular and Medical Genetics) ; Younis, Rasha (University of Birmingham. Department of Medical and Molecular Genetics) ; Maher, Eamonn R. (University of Birmingham. Centre for Rare Diseases and Personalised Medicine) ; Spencer, John (University of Sussex. Department of Chemistry, School of Life Sciences) ; Straatman Iwanowska, Ania (University College London. Laboratory for Molecular Cell Biology and Cell Biology Unit) ; Gissen, Paul (University College London. Institute of Child Health) ; Selim, Laila A.M. (Cairo University Children's Hospital. Department of Paediatric Neurology) ; Pintos Morell, Guillem (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Coroleu Lletget, Wifredo (Institut Germans Trias i Pujol. Hospital Universitari Germans Trias i Pujol) ; Mohammad, Shekeeb S. (University of Sydney. Institute for Neuroscience and Muscle Research) ; Yoganathan, Sangeetha (Christian Medical College Hospital. Department of Neurological Sciences (Vellore, Índia)) ; Dale, Russell C. (University of Sydney. Institute for Neuroscience and Muscle Research) ; Thomas, Maya (Christian Medical College Hospital. Department of Neurological Sciences (Vellore, Índia)) ; Rihel, Jason (University College London. Department of Cell and Developmental Biology) ; Bodamer, Olaf A. (Harvard Medical School. Division of Genetics and Genomics) ; Enns, Caroline A. (Oregon Health & Sciences University. Department of Cell, Development and Cancer Biology) ; Hayflick, Susan J. (Oregon Health and Science University. Department of Molecular and Medical Genetics) ; Clayton, Peter T. (University College London. Institute of Child Health) ; Mills, Philippa B. (University College London. Institute of Child Health) ; Kurian, Manju A. (University College London. Institute of Child Health) ; Wilson, Stephen W. (University College London. Department of Cell and Developmental Biology)
Although manganese is an essential trace metal, little is known about its transport and homeostatic regulation. Here we have identified a cohort of patients with a novel autosomal recessive manganese transporter defect caused by mutations in SLC39A14. [...]
2016 - 10.1038/ncomms11601
Nature communications, Vol. 7 Núm. 11601 (May 2016)  
19.
7 p, 525.4 KB Association of variations in HLA class II and other loci with susceptibility to EGFR-mutated lung adenocarcinoma / Shiraishi, Kouya (National Cancer Center Research Institute (Tòquio, Japó)) ; Okada, Yukinori (Tokyo Medical and Dental University) ; Takahashi, Atsushi (RIKEN Center for Integrative Medical Sciences (Yokohama, Japó)) ; Kamatani, Yoichiro (RIKEN Center for Integrative Medical Sciences (Yokohama, Japó)) ; Momozawa, Yukihide (RIKEN Center for Integrative Medical Sciences (Yokohama, Japó)) ; Ashikawa, Kyota (RIKEN Center for Integrative Medical Sciences (Yokohama, Japó)) ; Kunitoh, Hideo (Japanese Red Cross Medical Center (Tòquio, Japó)) ; Matsumoto, Shingo (National Cancer Center Research Institute (Tòquio, Japó)) ; Takano, Atsushi (The University of Tokyo) ; Shimizu, Kimihiro (Gunma University Hospital (Maebashi, Japó)) ; Goto, Akiteru (Akita University (Akita, Japó)) ; Tsuta, Koji (National Cancer Center Hospital (Tòquio, Japó)) ; Watanabe, Shun-ichi (National Cancer Center Hospital (Tòquio, Japó)) ; Ohe, Yuichiro (National Cancer Center Hospital (Tòquio, Japó)) ; Watanabe, Yukio (National Cancer Center Hospital (Tòquio, Japó)) ; Goto, Yasushi (National Cancer Center Hospital (Tòquio, Japó)) ; Nokihara, Hiroshi (National Cancer Center Hospital (Tòquio, Japó)) ; Furuta, Koh (National Cancer Center Hospital (Tòquio, Japó)) ; Yoshida, Akihiko (National Cancer Center Hospital (Tòquio, Japó)) ; Goto, Koichi (National Cancer Center Hospital East (Chiba, Japó)) ; Hishida, Tomoyuki (National Cancer Center Hospital East (Chiba, Japó)) ; Tsuboi, Masahiro (National Cancer Center Hospital East (Chiba, Japó)) ; Tsuchihara, Katsuya (National Cancer Center Research Institute (Tòquio, Japó)) ; Miyagi, Yohei (Kanagawa Cancer Center Research Institute (Yokohama, Japó)) ; Nakayama, Haruhiko (Kanagawa Cancer Center (Yokohama, Japó)) ; Yokose, Tomoyuki (Kanagawa Cancer Center (Yokohama, Japó)) ; Tanaka, Kazumi (Gunma University Hospital (Maebashi, Japó)) ; Nagashima, Toshiteru (Gunma University Hospital (Maebashi, Japó)) ; Ohtaki, Yoichi (Gunma University Hospital (Maebashi, Japó)) ; Maeda, Daichi (Akita University (Akita, Japó)) ; Imai, Kazuhiro (Akita University (Akita, Japó)) ; Minamiya, Yoshihiro (Akita University (Akita, Japó)) ; Sakamoto, Hiromi (National Cancer Center Research Institute (Tòquio, Japó)) ; Saito, Akira (StaGen Co., Ltd. (Tòquio, Japó)) ; Shimada, Yoko (National Cancer Center Research Institute (Tòquio, Japó)) ; Sunami, Kuniko (National Cancer Center Research Institute (Tòquio, Japó)) ; Saito, Motonobu (National Cancer Center Research Institute (Tòquio, Japó)) ; Inazawa, Johji (Tokyo Medical and Dental University) ; Nakamura, Yusuke (University of Chicago) ; Yoshida, Teruhiko (National Cancer Center Research Institute (Tòquio, Japó)) ; Yokota, Jun (Institut Germans Trias i Pujol. Institut de Medicina Predictiva i Personalitzada del Càncer) ; Matsuda, Fumihiko (Kyoto University) ; Matsuo, Keitaro (Aichi Cancer Center Research Institute (Nagoya, Japó)) ; Daigo, Yataro (The University of Tokyo) ; Kubo, Michiaki (RIKEN Center for Integrative Medical Sciences (Yokohama, Japó)) ; Kohno, Takashi (National Cancer Center Research Institute (Tòquio, Japó))
Lung adenocarcinoma driven by somatic EGFR mutations is more prevalent in East Asians (30-50%) than in European/Americans (10-20%). Here we investigate genetic factors underlying the risk of this disease by conducting a genome-wide association study, followed by two validation studies, in 3,173 Japanese patients with EGFR mutation-positive lung adenocarcinoma and 15,158 controls. [...]
2016 - 10.1038/ncomms12451
Nature Communications, Vol. 7 (August 2016) , art. 12451  
20.
7 p, 617.5 KB Identification of Siglec-1 null individuals infected with HIV-1 / Martínez Picado, Javier (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; McLaren, Paul J. (National HIV and Retrovirology Laboratory (Winnipeg, Canadà)) ; Erkizia, Itziar (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Martin, Maureen P. (Frederick National Laboratory for Cancer Research (Maryland, Estats Units d'Amèrica)) ; Benet, Susana (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Rotger, Margalida (University of Lausanne (Suïssa)) ; Dalmau, Judith (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Ouchi, Dan (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Wolinsky, Steven M. (Northwestern University Feinberg School of Medicine (Chicago, Estats Units d'Amèrica)) ; Penugonda, Sudhir (Northwestern University Feinberg School of Medicine (Chicago, Estats Units d'Amèrica)) ; Günthard, Huldrych F. (University Hospital Zurich (Suïssa)) ; Fellay, Jacques (École Polytechnique Fédérale de Lausanne (Suïssa)) ; Carrington, Mary (Frederick National Laboratory for Cancer Research (Maryland, Estats Units d'Amèrica)) ; Izquierdo Useros, Nuria (Institut Germans Trias i Pujol. Institut de Recerca de la Sida IrsiCaixa) ; Telenti, Amalio (J. Craig Venter Institute (La Jolla, Estats Units d'Amèrica))
Siglec-1/CD169 is a myeloid-cell surface receptor critical for HIV-1 capture and infection of bystander target cells. To dissect the role of SIGLEC1 in natura, we scan a large population genetic database and identify a loss-of-function variant (Glu88Ter) that is found in ∼1% of healthy people. [...]
2016 - 10.1038/ncomms12412
Nature communications, Vol. 7 Núm. 12412 (August 2016)  

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