Dipòsit Digital de Documents de la UAB 3 registres trobats  La cerca s'ha fet en 0.00 segons. 
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2 p, 193.7 KB Ibrutinib repurposing : from B-cell malignancies to solid tumors / Massó Vallés, Daniel (Vall d'Hebron. Institut d'Oncologia) ; Jauset, Toni (Vall d'Hebron. Institut d'Oncologia) ; Soucek, Laura (Vall d'Hebron. Institut d'Oncologia) ; Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular
Ibrutinib (Imbruvica®, also known as PCI-32765) is a first-in-class, irreversible small-molecule inhibitorof Bruton's Tyrosine Kinase (BTK) that binds covalently to cysteine C481 within the ATP-binding pocket. [...]
2016 - 10.18632/oncoscience.310
Oncoscience, Vol. 3, Num. 5-6 (may 2016) , p. 147-148  
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4 p, 1.6 MB Metabostemness : metaboloepigenetic reprogramming of cancer stem-cell functions / Menendez, Javier A. (Institut Català d'Oncologia) ; Corominas-Faja, Bruna (Institut Català d'Oncologia) ; Cuyàs Navarro, Elisabet (Institut Català d'Oncologia) ; Alarcón Cor, Tomás (Centre de Recerca Matematica)
Cancer researchers are currently embarking on one of their field's biggest challenges, namely the understanding of how cellular metabolism or certain classes of elite metabolites (e. g. , oncometabolites) can directly influence chromatin structure and the functioning of epi-transcriptional circuits to causally drive tumour formation. [...]
2014
Oncoscience, Vol. 1 (Dec. 2014) , p. 803-806  
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10 p, 687.1 KB A framework for genomic biomarker actionability and its use in clinical decision making / Vidwans, Smruti J. (CollabRx Inc. (USA)) ; Turski, Michelle L. (CollabRx Inc. (USA)) ; Janku, Filip (University of Texas. MD Anderson Cancer Center (USA)) ; Garrido-Laguna, Ignacio (University of Utah. Huntsman Cancer Institute (USA)) ; Munoz, Javier (Banner MD Anderson Cancer Center (USA)) ; Schwab, Richard (University of California. Moores Cancer Center (USA)) ; Subbiah, Vivek (University of Texas. MD Anderson Cancer Center (USA)) ; Rodón Ahnert, Jordi (Institut d'Oncologia de la Vall Hebron (VHIO)) ; Kurzrock, Razelle (University of California. Moores Cancer Center (USA)) ; Universitat Autònoma de Barcelona
The increasing scope and availability of genetic testing options for patients suffering from cancer has raised questions about how to use results of molecular diagnostics to inform patient care. For some biomarkers (e. [...]
2014 - 10.18632/oncoscience.90
Oncoscience, Vol. 1, Núm. 10 (October 2014) , p. 614-623  

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